Oxidation of apolipoprotein A-I by myeloperoxidase impairs the initial interactions with ABCA1 required for signaling and cholesterol export

Journal of Lipid Research

Volumn 51, Issue 7, 2010, Pages 1849-1858

  Shao, Baohai ^a   Tang, Chongren ^a   Heinecke, Jay W ^a   Oram, John F ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Atherogenesis; ATP binding cassette transporter A1; High density lipoprotein; Hydrogen peroxide; Hypochlorous acid; Janis kinase 2; Oxidation; Peroxynitrite

Indexed keywords

3 CHLOROTYROSINE; 3 NITROTYROSINE; ABC TRANSPORTER A1; APOLIPOPROTEIN A1; HIGH DENSITY LIPOPROTEIN; JANUS KINASE 2; MYELOPEROXIDASE; PHOSPHOLIPID; ABC TRANSPORTER; ABCA1 PROTEIN, HUMAN; CHOLESTEROL; PEROXIDASE;

ANIMAL CELL; ARTICLE; ATHEROGENESIS; CHLORINATION; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; MACROPHAGE; MOUSE; NITRATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN LIPID INTERACTION; PROTEIN METABOLISM; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; ANIMAL; CELL LINE; CHEMISTRY; HUMAN; METABOLISM; OXIDATION REDUCTION REACTION; PHYSIOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; APOLIPOPROTEIN A-I; ATP BINDING CASSETTE TRANSPORTER 1; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; CELL LINE; CHOLESTEROL; HUMANS; JANUS KINASE 2; OXIDATION-REDUCTION; PEROXIDASE; SIGNAL TRANSDUCTION;

EID: 77953497990     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M004085     Document Type: Article

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