Influence of N-terminal helix bundle stability on the lipid-binding properties of human apolipoprotein A-I

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1811, Issue 1, 2011, Pages 25-30

  Tanaka, Masafumi ^a   Dhanasekaran, Padmaja ^b   Nguyen, David ^b   Nickel, Margaret ^b   Takechi, Yuki ^c   Lund Katz, Sissel ^b   Phillips, Michael C ^b   Saito, Hiroyuki ^a,c  

^a KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Amphipathic helix; Apolipoprotein A I; Helix bundle structure; Lipid binding; Proline substitution

Indexed keywords

APOLIPOPROTEIN A1; MUTANT PROTEIN; PROLINE;

ALPHA HELIX; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; HYDROPHOBICITY; MUTATION; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN LIPID INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; STRUCTURE ACTIVITY RELATION; THERMODYNAMICS;

AMINO ACID SUBSTITUTION; APOLIPOPROTEIN A-I; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MUTATION, MISSENSE; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY;

EID: 78649798979     PISSN: 13881981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbalip.2010.10.003     Document Type: Article

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