Interaction between the N- and C-Terminal domains modulates the stability and lipid binding of apolipoprotein A-I

Biochemistry

Volumn 48, Issue 11, 2009, Pages 2529-2537

  Koyama, Mao ^a,b   Tanaka, Masafumi ^a,b   Dhanasekaran, Padmaja ^a,b   Sissel, Lund Katz ^a,b   Phillips, Michael C ^a,b   Saito, Hiroyuki ^a,b  

^a KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN A-I; APOLIPOPROTEIN A-I (APOA-I); C-TERMINAL DOMAINS; CHEMICAL DENATURATIONS; CONFORMATIONAL STABILITIES; DIMYRISTOYL; HELICAL SEGMENTS; HELIX BUNDLES; INTRA-MOLECULAR INTERACTIONS; LIPID BINDINGS; N- AND C- TERMINAL DOMAINS; N-TERMINAL DOMAINS; N-TERMINAL HELIXES; PHOSPHATIDYLCHOLINE; PROTEIN STABILITIES; SITE SPECIFICS; SPATIAL PROXIMITIES; TERTIARY STRUCTURES; TWO DOMAINS;

BINDING ENERGY; CONFORMATIONS; QUENCHING; STABILITY; UREA;

PLANTS (BOTANY);

APOLIPOPROTEIN A1; DIMYRISTOYLPHOSPHATIDYLCHOLINE; PHOSPHATIDYLCHOLINE;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; DENATURATION; HYDROPHOBICITY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN TERTIARY STRUCTURE; SOLUBILIZATION;

ANIMALS; APOLIPOPROTEIN A-I; HUMANS; KINETICS; MICE; PHOSPHATIDYLCHOLINES; PROTEIN BINDING; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY;

EID: 64849086373     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi802317v     Document Type: Article

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