메뉴 건너뛰기




Volumn 86, Issue 10, 2011, Pages 866-868

Possible new LNK mutations in myeloproliferative neoplasms

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; JANUS KINASE 2; LYMPHOCYTE ADAPTOR PROTEIN; PROTEIN SH2; UNCLASSIFIED DRUG;

EID: 84860412097     PISSN: 03618609     EISSN: 10968652     Source Type: Journal    
DOI: 10.1002/ajh.22107     Document Type: Letter
Times cited : (17)

References (20)
  • 1
    • 38349101871 scopus 로고    scopus 로고
    • Classification and diagnosis of myeloproliferative neoplasms: The 2008 World Health Organization criteria and point-of-care diagnostic algorithms
    • Tefferi A, Vardiman JW. Classification and diagnosis of myeloproliferative neoplasms: The 2008 World Health Organization criteria and point-of-care diagnostic algorithms. Leukemia 2008; 22: 14-22.
    • (2008) Leukemia , vol.22 , pp. 14-22
    • Tefferi, A.1    Vardiman, J.W.2
  • 2
    • 20144363192 scopus 로고    scopus 로고
    • Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
    • Baxter EJ, Scott LM, Campbell PJ, et al. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet 2005; 365: 1054-1061.
    • (2005) Lancet , vol.365 , pp. 1054-1061
    • Baxter, E.J.1    Scott, L.M.2    Campbell, P.J.3
  • 3
    • 33746437130 scopus 로고    scopus 로고
    • MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia
    • Pikman Y, Lee BH, Mercher T, et al. MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia. PLoS Med 2006; 3: e270.
    • (2006) PLoS Med , vol.3
    • Pikman, Y.1    Lee, B.H.2    Mercher, T.3
  • 4
    • 77954581139 scopus 로고    scopus 로고
    • Novel mutations and their functional and clinical relevance in myeloproliferative neoplasms: JAK2, MPL, TET2, ASXL1, CBL, IDH and IKZF1
    • Tefferi A. Novel mutations and their functional and clinical relevance in myeloproliferative neoplasms: JAK2, MPL, TET2, ASXL1, CBL, IDH and IKZF1. Leukemia 2010; 24: 1128-1138.
    • (2010) Leukemia , vol.24 , pp. 1128-1138
    • Tefferi, A.1
  • 5
    • 77953529304 scopus 로고    scopus 로고
    • JAK2 V617F and beyond: Role of genetics and aberrant signaling in the pathogenesis of myeloproliferative neoplasms
    • Oh ST, Gotlib J. JAK2 V617F and beyond: Role of genetics and aberrant signaling in the pathogenesis of myeloproliferative neoplasms. Expert Rev Hematol 2010; 3: 323-337.
    • (2010) Expert Rev Hematol , vol.3 , pp. 323-337
    • Oh, S.T.1    Gotlib, J.2
  • 6
    • 27144443646 scopus 로고    scopus 로고
    • Clinical implications of the JAK2 V617F mutation in essential thrombocythemia
    • Antonioli E, Guglielmelli P, Pancrazzi A, et al. Clinical implications of the JAK2 V617F mutation in essential thrombocythemia. Leukemia 2005; 19: 1847-1849.
    • (2005) Leukemia , vol.19 , pp. 1847-1849
    • Antonioli, E.1    Guglielmelli, P.2    Pancrazzi, A.3
  • 7
    • 33748684367 scopus 로고    scopus 로고
    • The JAK2-V617F mutation is frequently present at diagnosis in patients with essential thrombocythemia and polycythemia vera
    • Lippert E, Boissinot M, Kralovics R, et al. The JAK2-V617F mutation is frequently present at diagnosis in patients with essential thrombocythemia and polycythemia vera. Blood 2006; 108: 1865-1867.
    • (2006) Blood , vol.108 , pp. 1865-1867
    • Lippert, E.1    Boissinot, M.2    Kralovics, R.3
  • 8
    • 33846660947 scopus 로고    scopus 로고
    • JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis
    • Scott LM, Tong W, Levine RL, et al. JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis. N Engl J Med 2007; 356: 459-468.
    • (2007) N Engl J Med , vol.356 , pp. 459-468
    • Scott, L.M.1    Tong, W.2    Levine, R.L.3
  • 9
    • 33750534561 scopus 로고    scopus 로고
    • MPL515 mutations in myeloproliferative and other myeloid disorders: A study of 1182 patients
    • Pardanani AD, Levine RL, Lasho T, et al. MPL515 mutations in myeloproliferative and other myeloid disorders: A study of 1182 patients. Blood 2006; 108: 3472-3476.
    • (2006) Blood , vol.108 , pp. 3472-3476
    • Pardanani, A.D.1    Levine, R.L.2    Lasho, T.3
  • 10
    • 4544277651 scopus 로고    scopus 로고
    • Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis
    • Tong W, Lodish HF. Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis. J Exp Med 2004; 200: 569-580.
    • (2004) J Exp Med , vol.200 , pp. 569-580
    • Tong, W.1    Lodish, H.F.2
  • 11
    • 20444426803 scopus 로고    scopus 로고
    • Lnk inhibits erythropoiesis and Epo-dependent JAK2 activation and downstream signaling pathways
    • Tong W, Zhang J, Lodish HF. Lnk inhibits erythropoiesis and Epo-dependent JAK2 activation and downstream signaling pathways. Blood 2005; 105: 4604-4612.
    • (2005) Blood , vol.105 , pp. 4604-4612
    • Tong, W.1    Zhang, J.2    Lodish, H.F.3
  • 12
    • 0035811366 scopus 로고    scopus 로고
    • Lnk adaptor: novel negative regulator of B cell lymphopoiesis
    • Rudd CE. Lnk adaptor: novel negative regulator of B cell lymphopoiesis. Sci STKE. 2001; 2001: pe1.
    • (2001) Sci STKE. , vol.2001
    • Rudd, C.E.1
  • 13
    • 36148995898 scopus 로고    scopus 로고
    • Adaptor protein Lnk negatively regulates the mutant MPL, MPLW515L associated with myeloproliferative disorders
    • Gery S, Gueller S, Chumakova K, et al. Adaptor protein Lnk negatively regulates the mutant MPL, MPLW515L associated with myeloproliferative disorders. Blood 2007; 110: 3360-3364.
    • (2007) Blood , vol.110 , pp. 3360-3364
    • Gery, S.1    Gueller, S.2    Chumakova, K.3
  • 14
    • 67149083222 scopus 로고    scopus 로고
    • Lnk inhibits myeloproliferative disorder-associated JAK2 mutant, JAK2V617F
    • Gery S, Cao Q, Gueller S, et al. Lnk inhibits myeloproliferative disorder-associated JAK2 mutant, JAK2V617F. J Leukoc Biol 2009; 85: 957-965.
    • (2009) J Leukoc Biol , vol.85 , pp. 957-965
    • Gery, S.1    Cao, Q.2    Gueller, S.3
  • 15
    • 0037124306 scopus 로고    scopus 로고
    • Cytokine signaling and hematopoietic homeostasis are disrupted in Lnk-deficient mice
    • Velazquez L, Cheng AM, Fleming HE, et al. Cytokine signaling and hematopoietic homeostasis are disrupted in Lnk-deficient mice. J Exp Med 2002; 195: 1599-1611.
    • (2002) J Exp Med , vol.195 , pp. 1599-1611
    • Velazquez, L.1    Cheng, A.M.2    Fleming, H.E.3
  • 16
    • 77953485892 scopus 로고    scopus 로고
    • Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms
    • Oh ST, Simonds EF, Jones C, et al. Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms. Blood 2010; 116: 988-992.
    • (2010) Blood , vol.116 , pp. 988-992
    • Oh, S.T.1    Simonds, E.F.2    Jones, C.3
  • 17
    • 77958021645 scopus 로고    scopus 로고
    • LNK mutation studies in blast-phase myeloproliferative neoplasms, and in chronic-phase disease with TET2, IDH, JAK2 or MPL mutations
    • Pardanani A, Lasho T, Finke C, et al. LNK mutation studies in blast-phase myeloproliferative neoplasms, and in chronic-phase disease with TET2, IDH, JAK2 or MPL mutations. Leukemia 2010; 24: 1713-1718.
    • (2010) Leukemia , vol.24 , pp. 1713-1718
    • Pardanani, A.1    Lasho, T.2    Finke, C.3
  • 18
    • 77956670899 scopus 로고    scopus 로고
    • LNK mutations in JAK2 mutation-negative erythrocytosis
    • Lasho TL, Pardanani A, Tefferi A. LNK mutations in JAK2 mutation-negative erythrocytosis. N Engl J Med 2010; 363: 1189-1190.
    • (2010) N Engl J Med , vol.363 , pp. 1189-1190
    • Lasho, T.L.1    Pardanani, A.2    Tefferi, A.3
  • 19
    • 78650279826 scopus 로고    scopus 로고
    • Expression level and differential JAK2-V617F-binding of the adaptor protein Lnk regulates JAK2-mediated signals in myeloproliferative neoplasms
    • Baran-Marszak F, Magdoud H, Desterke C, et al. Expression level and differential JAK2-V617F-binding of the adaptor protein Lnk regulates JAK2-mediated signals in myeloproliferative neoplasms. Blood 2010; 116: 5961-5971.
    • (2010) Blood , vol.116 , pp. 5961-5971
    • Baran-Marszak, F.1    Magdoud, H.2    Desterke, C.3
  • 20
    • 77953193307 scopus 로고    scopus 로고
    • Lnk constrains myeloproliferative diseases in mice
    • Bersenev A, Wu C, Balcerek J, et al. Lnk constrains myeloproliferative diseases in mice. J Clin Invest 2010; 120: 2058-2069.
    • (2010) J Clin Invest , vol.120 , pp. 2058-2069
    • Bersenev, A.1    Wu, C.2    Balcerek, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.