Lipid membrane templates the ordering and induces the fibrillogenesis of Alzheimer's disease amyloid-β peptide

Proteins: Structure, Function and Genetics

Volumn 72, Issue 1, 2008, Pages 1-24

  Chi, Eva Y ^a   Ege, Canay ^a   Winans, Amy ^a   Majewski, Jaroslaw ^b   Wu, Guohui ^a   Kjaer, Kristian ^c,d   Lee, Ka Yee C ^a,e  

^a UNIVERSITY OF CHICAGO   (United States)

^b LOS ALAMOS NATIONAL LABORATORY   (United States)

^c MAX PLANCK INSTITUTE OF COLLOIDS AND INTERFACES   (Germany)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

^e UNIVERSITY OF CHICAGO   (United States)

Author keywords

Alzheimer's disease; Fibril formation; Grazing incidence X ray diffraction; Lipid monolayer; Lipid vesicles; Protein aggregation; Protein conformation; Protein lipid interactions; X ray reflectivity

Indexed keywords

1 PALMITOYL 2 OLEOLYL SN GLYCERO 3 [PHOSPHO RAC (1 GLYCEROL)]; 1,2 DIPALMITOYL 3 TRIMETHYLAMMONIUM PROPANE; 1,2 DIPALMITOYL SN GLYCERO 3 [PHOSPHO RAC (1 GLYCEROL)]; AMPHOLYTE; AMYLOID; AMYLOID BETA PROTEIN; CRYSTALLIN; DIPALMITOYLPHOSPHATIDYLCHOLINE; GLYCEROPHOSPHOLIPID; LIPID;

ALZHEIMER DISEASE; ARTICLE; BETA SHEET; FIBER; INCIDENCE; LIPID ABSORPTION; LIPID MEMBRANE; LIPID MONOLAYER; LIPID VESICLE; NEUTRON SCATTERING; PRIORITY JOURNAL; PROTEIN STRUCTURE; X RAY; X RAY DIFFRACTION;

ADSORPTION; AIR; ALZHEIMER DISEASE; AMYLOID; AMYLOID BETA-PROTEIN; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIMYRISTOYLPHOSPHATIDYLCHOLINE; FLUORESCENCE; LIPID BILAYERS; NEUTRONS; PROPANE; QUATERNARY AMMONIUM COMPOUNDS; SCATTERING, RADIATION; WATER; X-RAYS;

EID: 44949154514     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.21887     Document Type: Article

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