Induction of Foxp3-expressing regulatory T-cells by donor blood transfusion is required for tolerance to rat liver allografts

PLoS ONE

Volumn 4, Issue 11, 2009, Pages

  Abe, Yuta ^a   Urakami, Hidejiro ^a   Ostanin, Dmitry ^a   Zibari, Gazi ^b   Hayashida, Tetsu ^c   Kitagawa, Yuko ^c   Grisham, Matthew B ^a  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b Louisiana State University School of Medicine Shreveport   (United States)

^c KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIGEN; INTERLEUKIN 2 RECEPTOR ALPHA; TRANSCRIPTION FACTOR FOXP3; CYTOKINE; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, RAT; IMMUNOSUPPRESSIVE AGENT;

ALLOTRANSPLANTATION; ANIMAL EXPERIMENT; ARTICLE; BLOOD TRANSFUSION; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL FUNCTION; CELL PROLIFERATION; CONTROLLED STUDY; GENE EXPRESSION; LIVER GRAFT REJECTION; LIVER TRANSPLANTATION; MALE; NONHUMAN; PHENOTYPE; RAT; REGULATORY T LYMPHOCYTE; SURVIVAL TIME; T LYMPHOCYTE ACTIVATION; ANIMAL; CHEMISTRY; CYTOLOGY; GRAFT REJECTION; IMMUNOLOGY; KINETICS; LEWIS RAT; METABOLISM; METHODOLOGY; PHYSIOLOGY;

AGOUTI; RATTUS;

ANIMALS; BLOOD TRANSFUSION; CD4-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CYTOKINES; FORKHEAD TRANSCRIPTION FACTORS; GRAFT REJECTION; IMMUNOSUPPRESSIVE AGENTS; ISOANTIGENS; KINETICS; LIVER TRANSPLANTATION; MALE; RATS; RATS, INBRED LEW; T-LYMPHOCYTES, REGULATORY;

EID: 71049123596     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0007840     Document Type: Article

References (26)

1. 2007 Annual Report of the US Organ Procurement and Transplantation Network and the Scientific Registry of Transplant Recipients. Transplant Data 1997-2006; Health Resources and Services Admin; Healthcare Systems Bureau, Division of Transplantation, Rockville, MD. 2007.
2. Jain A, Nalesnik M, Reyes J, Pokharna R, Mazariegos G, et al. (2002) Posttransplant lymphoproliferative disorders in liver transplantation: a 20-year experience. Ann Surg 236: 429-436.
3. Patel R, Paya CV (1997) Infections in solid-organ transplant recipients. Clin Microbiol Rev 10: 86-124.
4. Katz MR, Barnhart GR, Goldman MH, Rider S, Hastillo A, et al. (1987) Pretransplant transfusions in cardiac allograft recipients. Transplantation 43: 499-501.
5. Opelz G, Vanrenterghem Y, Kirste G, Gray DW, Horsburgh T, et al. (1997) Prospective evaluation of pretransplant blood transfusions in cadaver kidney recipients. Transplantation 63: 964-967.
6. Alexander JW, Babcock GF, First MR, Davies CB, Madden RL, et al. (1992) The induction of immunologic hyporesponsiveness by preoperative donor-specific transfusions and cyclosporine in human cadaveric transplants. A preliminary trial. Transplantation 53: 423-427.
7. Baquerizo A, Kamada N, Millis JM, Iwaki Y, Terasaki PI, et al. (1989) Donor-specific serum transfusion prolongs survival of orthotopic liver transplantation in the rat. Transplant Proc 21: 1179-1180.
8. Flye MW, Burton K, Mohanakumar T, Brennan D, Keller C, et al. (1995) Donor-specific transfusions have long-term beneficial effects for human renal allografts. Transplantation 60: 1395-1401.
9. Potter DE, Portale AA, Melzer JS, Feduska NJ, Garovoy MR, et al. (1991) Are blood transfusions beneficial in the cyclosporine era? Pediatr Nephrol 5: 168-172.
10. Quigley RL, Wood KJ, Morris PJ (1989) Transfusion induces blood donor-specific suppressor cells. J Immunol 142: 463-470.
11. van Twuyver E, Mooijaart RJ, ten Berge IJ, van der Horst AR, Wilmink JM, et al. (1991) Pretransplantation blood transfusion revisited. N Engl J Med 325: 1210-1213.
12. Yamaguchi Y, Harland RC, Wyble C, Bollinger RR (1989) The role of class I major histocompatibility complex antigens in prolonging the survival of hepatic allografts in the rat. Transplantation 47: 171-177.
13. Josien R, Douillard P, Guillot C, Muschen M, Anegon I, et al. (1998) A critical role for transforming growth factor-beta in donor transfusion-induced allograft tolerance. J Clin Invest 102: 1920-1926.
14. Miyanari N, Yamaguchi Y, Matsuno K, Tominaga A, Goto M, et al. (1997) Persistent infiltration of CD. Hepatology 25: 1008-1013.
15. Yamaguchi Y, Goto M, Makino Y, Kikuchi N, Hamaguchi H (1996) Prolonged survival of rat hepatic allografts pretreated with a single donor-specific blood transfusion: the distribution of donor cells expressing class I major histocompatibility complex antigens in the recipient. J Surg Res 61: 23-29.
16. Kitade H, Kawai M, Rutgeerts O, Landuyt W, Waer M, et al. (2005) Early presence of regulatory cells in transplanted rats rendered tolerant by donor-specific blood transfusion. J Immunol 175: 4963-4970.
17. Kamada N, Calne RY (1979) Orthotopic liver transplantation in the rat. Technique using cuff for portal vein anastomosis and biliary drainage. Transplantation 28: 47-50.
18. Urakami H, Ostanin DV, Hunig T, Grisham MB (2006) Combination of donorspecific blood transfusion with anti-CD28 antibody synergizes to prolong graft survival in rat liver transplantation. Transplant Proc 38: 3244-3246.
19. Degauque N, Lair D, Braudeau C, Haspot F, Sebille F, et al. (2007) Development of. Eur J Immunol 37: 147-156.
20. Kataoka M, Margenthaler JA, Ku G, Flye MW (2003) Development of infectious tolerance after donor-specific transfusion and rat heart transplantation. J Immunol 171: 204-211.
21. Dallman MJ, Wood KJ, Morris PJ (1987) Specific cytotoxic T cells are found in the nonrejected kidneys of blood-transfused rats. J Exp Med 165: 566-571.
22. Douillard P, Vignes C, Josien R, Chiffoleau E, Heslan JM, et al. (1999) Reassessment of the role of CD8+ T cells in the induction of allograft tolerance by donor-specific blood transfusion. Eur J Immunol 29: 1919-1924.
23. Shimizu Y, Otomo N, Yu S, Margenthaler JA, Flye MW (2001) Donor-specific antigen transfusion-mediated cardiac allograft tolerance is prevented by prior treatment with anti-CD8, but not anti-CD4, antibody. Transplant Proc 33: 150-151.
24. Olson TS, Bamias G, Naganuma M, Rivera-Nieves J, Burcin TL, et al. (2004) Expanded B cell population blocks regulatory T cells and exacerbates ileitis in a murine model of Crohn disease. J Clin Invest 114: 389-398.
25. Armstrong HE, Bolton EM, McMillan I, Spencer SC, Bradley JA (1987) Prolonged survival of actively enhanced rat renal allografts despite accelerated cellular infiltration and rapid induction of both class I and class II MHC antigens. J Exp Med 165: 891-907.
26. Bugeon L, Cuturi MC, Hallet MM, Paineau J, Chabannes D, et al. (1992) Peripheral tolerance of an allograft in adult rats-characterization by low interleukin-2 and interferon-gamma mRNA levels and by strong accumulation of major histocompatibility complex transcripts in the graft. Transplantation 54: 219-225.