Insulin analogues differently activate insulin receptor isoforms and post-receptor signalling

Diabetologia

Volumn 53, Issue 8, 2010, Pages 1743-1753

  Sciacca, L ^a   Cassarino, M F ^a   Genua, M ^a   Pandini, G ^a   Le Moli, R ^a   Squatrito, S ^a   Vigneri, R ^a  

^a UNIVERSITY OF CATANIA   (Italy)

Author keywords

IGF1R; Insulin analogues; Insulin receptor; Insulin receptor isoforms; Intracellular signalling; Mitogenic effects

Indexed keywords

INSULIN; INSULIN ASPART; INSULIN DERIVATIVE; INSULIN DETEMIR; INSULIN GLARGINE; INSULIN GLULISINE; INSULIN LISPRO; INSULIN RECEPTOR; LONG ACTING DRUG; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; SHORT ACTING DRUG; SOMATOMEDIN;

ANIMAL CELL; ARTICLE; CELL GROWTH; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; DRUG PROTEIN BINDING; DRUG RECEPTOR BINDING; ENZYME ACTIVATION; ENZYME KINETICS; ENZYME SUBSTRATE; FIBROBLAST; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANALOGS AND DERIVATIVES; ANALYSIS OF VARIANCE; ANIMAL; CELL CULTURE; DRUG EFFECTS; HUMAN; METABOLISM; PHOSPHORYLATION; WESTERN BLOTTING;

ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; CELL PROLIFERATION; CELLS, CULTURED; HUMANS; INSULIN; MICE; PHOSPHORYLATION; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION;

EID: 77955515434     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-010-1760-6     Document Type: Article

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