TAC3/TACR3 mutations reveal preferential activation of gonadotropin- releasing hormone release by neurokinin B in neonatal life followed by reversal in adulthood

Journal of Clinical Endocrinology and Metabolism

Volumn 95, Issue 6, 2010, Pages 2857-2867

  Gianetti, Elena ^a   Tusset, Cintia ^b   Noel, Sekoni D ^c   Au, Margaret G ^a   Dwyer, Andrew A ^a   Hughes, Virginia A ^a   Abreu, Ana Paula ^c   Carroll, Jessica ^c   Trarbach, Ericka ^b   Silveira, Leticia F G ^b   Costa, Elaine M F ^b   De Mendonça, Berenice Bilharinho ^b   De Castro, Margaret ^b   Lofrano, Adriana ^d   Hall, Janet E ^a   Bolu, Erol ^e   Ozata, Metin ^e   Quinton, Richard ^f   Amory, John K ^g   Stewart, Susan E ^h   Arlt, Wiebke ⁱ   Cole, Trevor R ^h   Crowley, William F ^a   Kaiser, Ursula B ^c   Latronico, Ana Claudia ^b   Seminara, Stephanie B ^a   more..

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d HOSPITAL UNIVERSITÁRIO DE BRASÍLIA   (Brazil)

^e GULHANE SCHOOL OF MEDICINE   (Turkey)

^f NEWCASTLE UNIVERSITY   (United Kingdom)

^g UNIVERSITY OF WASHINGTON MEDICAL CENTER   (United States)

^h BIRMINGHAM CHILDREN S HOSPITAL NHS FOUNDATION TRUST   (United Kingdom)

ⁱ UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GONADORELIN; NEUROKININ B; NEUROKININ 3 RECEPTOR; TACHYKININ; TACHYKININ RECEPTOR;

ADULT; ARTICLE; BASE PAIRING; BREAST DEVELOPMENT; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; GENE; GENE DELETION; GENE MUTATION; GENE SEQUENCE; GENETIC SCREENING; GENETIC VARIABILITY; GENOTYPE PHENOTYPE CORRELATION; HOMOZYGOSITY; HORMONE RELEASE; HUMAN; HYPOGONADOTROPIC HYPOGONADISM; HYPOTHALAMUS HYPOPHYSIS GONAD SYSTEM; IN VITRO STUDY; MAJOR CLINICAL STUDY; MALE; MICROPENIS; NEWBORN; NONSENSE MUTATION; NUCLEOTIDE SEQUENCE; PREVALENCE; PRIORITY JOURNAL; SEXUAL DEVELOPMENT; TAC3 GENE; TACR3 GENE; ADOLESCENT; AMINO ACID SEQUENCE; ANIMAL; CELL STRAIN COS1; CERCOPITHECUS; ETHNIC GROUP; FERTILITY; GENETIC TRANSFECTION; GENETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; PEDIGREE; PHYSIOLOGY; PUBERTY; STOP CODON;

ADOLESCENT; ADULT; AMINO ACID SEQUENCE; ANIMALS; CERCOPITHECUS AETHIOPS; CODON, NONSENSE; COS CELLS; DNA MUTATIONAL ANALYSIS; ETHNIC GROUPS; FEMALE; FERTILITY; GENETIC VARIATION; GONADOTROPIN-RELEASING HORMONE; HUMANS; INFANT, NEWBORN; MALE; MOLECULAR SEQUENCE DATA; MUTATION; NEUROKININ B; PEDIGREE; PUBERTY; RECEPTORS, NEUROKININ-3; RECEPTORS, TACHYKININ; SEX CHARACTERISTICS; TACHYKININS; TRANSFECTION; YOUNG ADULT;

EID: 77954517193     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2009-2320     Document Type: Article

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