Beta-adrenoceptor pathway enhances mitochondrial function in human neural stem cells via rotary cell culture system

Journal of Neuroscience Methods

Volumn 207, Issue 2, 2012, Pages 130-136

  Chiang, Ming Chang ^a   Lin, Heng ^b   Cheng, Yi Chuan ^c   Yen, Chia Hui ^d   Huang, Rong Nan ^e   Lin, Kuan Hung ^f  

^a FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c CHANG GUNG UNIVERSITY   (Taiwan)

^d MING CHUAN UNIVERSITY   (Taiwan)

^e NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^f CHINESE CULTURE UNIVERSITY   (Taiwan)

Author keywords

Human neural stem cells; Mitochondrial function; PGC1 ; Rotary cell culture system

Indexed keywords

BETA ADRENERGIC RECEPTOR; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GA BINDING PROTEIN; MITOCHONDRIAL TRANSCRIPTION FACTOR A; NUCLEAR RESPIRATORY FACTOR 1;

ARTICLE; CELL FUNCTION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MICROGRAVITY; MITOCHONDRION; NEURAL STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHEAR STRENGTH;

CELL CULTURE TECHNIQUES; CELL SURVIVAL; HUMANS; MITOCHONDRIA; NEURAL PATHWAYS; NEURAL STEM CELLS; RECEPTORS, ADRENERGIC, BETA; SIGNAL TRANSDUCTION; UP-REGULATION; WEIGHTLESSNESS SIMULATION;

EID: 84860336997     PISSN: 01650270     EISSN: 1872678X     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2012.04.005     Document Type: Article

References (48)

1. Cai Y., Wu P., Ozen M., Yu Y., Wang J., Ittmann M., et al. Gene expression profiling and analysis of signaling pathways involved in priming and differentiation of human neural stem cells. Neuroscience 2006, 138:133-148.
2. Cameron H.A., McKay R.D. Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus. J Comp Neurol 2001, 435:406-417.
3. Chen J., Chen R., Gao S. Morphological characteristics and proliferation of keratocytes cultured under simulated microgravity. Artif Organs 2007, 31:722-731.
4. Chiang M.C., Chen H.M., Lai H.L., Chen H.W., Chou S.Y., Chen C.M., et al. The A2A adenosine receptor rescues the urea cycle deficiency of Huntington's disease by enhancing the activity of the ubiquitin-proteasome system. Hum Mol Genet 2009, 18:2929-2942.
5. Chiang M.C., Chern Y., Huang R.N. PPARgamma rescue of the mitochondrial dysfunction in Huntington's disease. Neurobiol Dis 2012, 45:322-328.
6. Chiang M.C., Chern Y., Juo C.G. The dysfunction of hepatic transcriptional factors in mice with Huntington's disease. Biochim Biophys Acta 2011, 1812:1111-1120.
7. Clement J.Q., Lacy S.M., Wilson B.L. Gene expression profiling of human epidermal keratinocytes in simulated microgravity and recovery cultures. Genomics Proteomics Bioinformatics 2008, 6:8-28.
8. Cummings L.J., Waters S.L. Tissue growth in a rotating bioreactor. Part II: fluid flow and nutrient transport problems. Math Med Biol 2007, 24:169-208.
9. Dabos K.J., Nelson L.J., Bradnock T.J., Parkinson J.A., Sadler I.H., Hayes P.C., et al. The simulated microgravity environment maintains key metabolic functions and promotes aggregation of primary porcine hepatocytes. Biochim Biophys Acta 2001, 1526:119-130.
10. Dai Z.Q., Wang R., Ling S.K., Wan Y.M., Li Y.H. Simulated microgravity inhibits the proliferation and osteogenesis of rat bone marrow mesenchymal stem cells. Cell Prolif 2007, 40:671-684.
11. Di Loreto S., Sebastiani P., Benedetti E., Zimmitti V., Caracciolo V., Amicarelli F., et al. Transient maintenance in bioreactor improves health of neuronal cells. In Vitro Cell Dev Biol Anim 2006, 42:134-142.
12. Fournier M.V., Martin K.J. Transcriptome profiling in clinical breast cancer: from 3D culture models to prognostic signatures. J Cell Physiol 2006, 209:625-630.
13. Hahn H., Muller M., Lowenheim H. Whole organ culture of the postnatal sensory inner ear in simulated microgravity. J Neurosci Methods 2008, 171:60-71.
14. Hallbergson A.F., Gnatenco C., Peterson D.A. Neurogenesis and brain injury: managing a renewable resource for repair. J Clin Invest 2003, 112:1128-1133.
15. Handschin C., Rhee J., Lin J., Tarr P.T., Spiegelman B.M. An autoregulatory loop controls peroxisome proliferator-activated receptor gamma coactivator 1alpha expression in muscle. Proc Natl Acad Sci USA 2003, 100:7111-7116.
16. Herzig S., Hedrick S., Morantte I., Koo S.H., Galimi F., Montminy M. CREB controls hepatic lipid metabolism through nuclear hormone receptor PPAR-gamma. Nature 2003, 426:190-193.
17. Jhaveri D.J., Mackay E.W., Hamlin A.S., Marathe S.V., Nandam L.S., Vaidya V.A., et al. Norepinephrine directly activates adult hippocampal precursors via beta3-adrenergic receptors. J Neurosci 2010, 30:2795-2806.
18. Karamitri A., Shore A.M., Docherty K., Speakman J.R., Lomax M.A. Combinatorial transcription factor regulation of the cyclic AMP-response element on the Pgc-1alpha promoter in white 3T3-L1 and brown HIB-1B preadipocytes. J Biol Chem 2009, 284:20738-20752.
19. Kleinman H.K., Luckenbill-Edds L., Cannon F.W., Sephel G.C. Use of extracellular matrix components for cell culture. Anal Biochem 1987, 166:1-13.
20. Kruger G.M., Mosher J.T., Bixby S., Joseph N., Iwashita T., Morrison S.J. Neural crest stem cells persist in the adult gut but undergo changes in self-renewal, neuronal subtype potential, and factor responsiveness. Neuron 2002, 35:657-669.
21. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227:680-685.
22. Lie D.C., Song H., Colamarino S.A., Ming G.L., Gage F.H. Neurogenesis in the adult brain: new strategies for central nervous system diseases. Annu Rev Pharmacol Toxicol 2004, 44:399-421.
23. Lin H.J., O'Shaughnessy T.J., Kelly J., Ma W. Neural stem cell differentiation in a cell-collagen-bioreactor culture system. Brain Res Dev Brain Res 2004, 153:163-173.
24. Lindvall O., Kokaia Z. Stem cells for the treatment of neurological disorders. Nature 2006, 441:1094-1096.
25. Mantamadiotis T., Lemberger T., Bleckmann S.C., Kern H., Kretz O., Martin Villalba A., et al. Disruption of CREB function in brain leads to neurodegeneration. Nat Genet 2002, 31:47-54.
26. Mayr B., Montminy M. Transcriptional regulation by the phosphorylation-dependent factor CREB. Nat Rev Mol Cell Biol 2001, 2:599-609.
27. McGill J.K., Beal M.F. PGC-1alpha: a new therapeutic target in Huntington's disease?. Cell 2006, 127:465-468.
28. Nakagawa S., Kim J.E., Lee R., Malberg J.E., Chen J., Steffen C., et al. Regulation of neurogenesis in adult mouse hippocampus by cAMP and the cAMP response element-binding protein. J Neurosci 2002, 22:3673-3682.
29. Nistor G., Seiler M.J., Yan F., Ferguson D., Keirstead H.S. Three-dimensional early retinal progenitor 3D tissue constructs derived from human embryonic stem cells. J Neurosci Methods 2010, 190:63-70.
30. Norsk P. Cardiovascular and fluid volume control in humans in space. Curr Pharm Biotechnol 2005, 6:325-330.
31. Puigserver P., Spiegelman B.M. Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1alpha): transcriptional coactivator and metabolic regulator. Endocr Rev 2003, 24:78-90.
32. Quintanilla R.A., Jin Y.N., Fuenzalida K., Bronfman M., Johnson G.V. Rosiglitazone treatment prevents mitochondrial dysfunction in mutant huntingtin-expressing cells: possible role of peroxisome proliferator-activated receptor-gamma (PPARgamma) in the pathogenesis of Huntington disease. J Biol Chem 2008, 283:25628-25637.
33. Reh T.A. Neural stem cells: form and function. Nat Neurosci 2002, 5:392-394.
34. Roberts T.J., Price J., Williams S.C., Modo M. Preservation of striatal tissue and behavioral function after neural stem cell transplantation in a rat model of Huntington's disease. Neuroscience 2006, 139:1187-1199.
35. Schenk P.W., Snaar-Jagalska B.E. Signal perception and transduction: the role of protein kinases. Biochim Biophys Acta 1999, 1449:1-24.
36. Schwarz R.P., Goodwin T.J., Wolf D.A. Cell culture for three-dimensional modeling in rotating-wall vessels: an application of simulated microgravity. J Tissue Cult Method 1992, 14:51-57.
37. Song H.J., Stevens C.F., Gage F.H. Neural stem cells from adult hippocampus develop essential properties of functional CNS neurons. Nat Neurosci 2002, 5:438-445.
38. St-Pierre J., Drori S., Uldry M., Silvaggi J.M., Rhee J., Jager S., et al. Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators. Cell 2006, 127:397-408.
39. Stoker A.W., Streuli C.H., Martins-Green M., Bissell M.J. Designer microenvironments for the analysis of cell and tissue function. Curr Opin Cell Biol 1990, 2:864-874.
40. Temple S. The development of neural stem cells. Nature 2001, 414:112-117.
41. Ursino M.G., Vasina V., Raschi E., Crema F., De Ponti F. The beta3-adrenoceptor as a therapeutic target: current perspectives. Pharmacol Res 2009, 59:221-234.
42. Vincent L., Avancena P., Cheng J., Rafii S., Rabbany S.Y. Simulated microgravity impairs leukemic cell survival through altering VEGFR-2/VEGF-A signaling pathway. Ann Biomed Eng 2005, 33:1405-1410.
43. Vunjak-Novakovic G., Searby N., De Luis J., Freed L.E. Microgravity studies of cells and tissues. Ann N Y Acad Sci 2002, 974:504-517.
44. Walton M.R., Dragunow I. Is CREB a key to neuronal survival?. Trends Neurosci 2000, 23:48-53.
45. Wang S.S., Good T.A. Effect of culture in a rotating wall bioreactor on the physiology of differentiated neuron-like PC12 and SH-SY5Y cells. J Cell Biochem 2001, 83:574-584.
46. Ward N.E., Pellis N.R., Risin S.A., Risin D. Gene expression alterations in activated human T-cells induced by modeled microgravity. J Cell Biochem 2006, 99:1187-1202.
47. Waters S.L., Cummings L.J., Shakesheff K.M., Rose F.R. Tissue growth in a rotating bioreactor. Part I: mechanical stability. Math Med Biol 2006, 23:311-337.
48. Wilson-Fritch L., Burkart A., Bell G., Mendelson K., Leszyk J., Nicoloro S., et al. Mitochondrial biogenesis and remodeling during adipogenesis and in response to the insulin sensitizer rosiglitazone. Mol Cell Biol 2003, 23:1085-1094.