Systemic leptin administration in supraphysiological doses maintains bone mineral density and mechanical strength despite significant weight loss

Endocrinology

Volumn 153, Issue 5, 2012, Pages 2245-2253

  Stunes, Astrid K ^a   Westbroek, Irene ^b   Gordeladze, Jan O ^c   Gustafsson, Björn I ^a,d   Reseland, Janne E ^e   Syversen, Unni ^a,d  

^a NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^b ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^c UNIVERSITY OF OSLO   (Norway)

^d TRONDHEIM UNIVERSITY HOSPITAL   (Norway)

^e UNIVERSITY OF OSLO   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; BODY WEIGHT; BONE DENSITY; BONE STRENGTH; CONTINUOUS INFUSION; CONTROLLED STUDY; DRUG MEGADOSE; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; FEMUR; FISCHER 344 RAT; LOW DRUG DOSE; METAPHYSIS; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; PINCH STRENGTH; PRIORITY JOURNAL; RAT; WEIGHT REDUCTION;

ANIMALS; BODY WEIGHT; BONE DENSITY; FEMALE; FEMUR; LEPTIN; RATS; RATS, INBRED F344; WEIGHT LOSS;

EID: 84860316770     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2011-1848     Document Type: Article

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