Cell-based therapy to promote angiogenesis in the brain following ischemic damage

Current Vascular Pharmacology

Volumn 10, Issue 3, 2012, Pages 285-288

  Uemura, Masahiro ^a   Kasahara, Yukiko ^a   Nagatsuka, Kazuyuki ^a   Taguchi, Akihiko ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Angiogenesis; CD34 positive cells; Neural stem cells; Neurogenesis; Stroke

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; ERYTHROPOIETIN; GRANULOCYTE COLONY STIMULATING FACTOR; VASCULOTROPIN;

ANGIOGENESIS; BONE MARROW TRANSPLANTATION; BRAIN BLOOD VESSEL; BRAIN ISCHEMIA; BRAIN MICROCIRCULATION; CELL THERAPY; ENDOTHELIAL PROGENITOR CELL; HUMAN; MEDICAL RESEARCH; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL TRANSPLANTATION; NEUROPROTECTION; NONHUMAN; REVIEW;

ANIMALS; ANTIGENS, CD34; BRAIN; BRAIN ISCHEMIA; HUMANS; MICROVESSELS; NEOVASCULARIZATION, PHYSIOLOGIC; NEUROGENESIS; REGENERATION; STEM CELL TRANSPLANTATION; STROKE;

EID: 84860311713     PISSN: 15701611     EISSN: 18756212     Source Type: Journal    
DOI: 10.2174/157016112799959369     Document Type: Review

References (43)

1. Pearson TA. Cardiovascular disease in developing countries: myths, realities, and opportunities. Cardiovasc Drugs Ther 1999; 13: 95-104.
2. Hacke W, Donnan G, Fieschi C, et al. Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials. Lancet 2004; 363: 768-74.
3. Lansberg MG, Albers GW, Wijman CA. Symptomatic intracerebral hemorrhage following thrombolytic therapy for acute ischemic stroke: a review of the risk factors. Cerebrovasc Dis 2007; 24: 1-10.
4. Kondziolka D, Wechsler L, Goldstein S, et al. Transplantation of cultured human neuronal cells for patients with stroke. Neurology 2000; 55: 565-9.
5. Savitz SI, Dinsmore J, Wu J, et al. Neurotransplantation of fetal porcine cells in patients with basal ganglia infarcts: a preliminary safety and feasibility study. Cerebrovasc Dis 2005; 20: 101-7.
6. Taguchi A, Ohtani M, Soma T, et al. Therapeutic angiogenesis by autologous bone-marrow transplantation in a general hospital setting. Eur J Vasc Endovasc Surg 2003; 25: 276-8.
7. Schächinger V, Erbs S, Elsässer A, et al. Improved clinical outcome after intracoronary administration of bone-marrow-derived progenitor cells in acute myocardial infarction: final 1-year results of the REPAIR-AMI trial. Eur Heart J 2006; 27: 2775-83.
8. Alvarez-Buylla A, Garcia-Verdugo JM. Neurogenesis in adult subventricular zone. J Neurosci 2002; 22: 629-34.
9. Alvarez-Buylla A, Herrera DG, Wichterle H. The subventricular zone: source of neuronal precursors for brain repair. Prog Brain Res 2000; 127: 1-11.
10. Ma DK, Bonaguidi MA, Ming GL, Song H. Adult neural stem cells in the mammalian central nervous system. Cell Res 2009; 19: 6726-82.
11. Lledo PM, Alonso M, Grubb MS. Adult neurogenesis and functional plasticity in neuronal circuits. Nat Rev Neurosci 2006; 7: 179-93.
12. Gage FH. Molecular and cellular mechanisms contributing to the regulation, proliferation and differentiation of neural stem cells in the adult dentate gyrus. Keio J Med 2010; 59: 79-83.
13. Suh H, Consiglio A, Ray J, et al. In vivo fate analysis reveals the multipotent and self-renewal capacities of Sox2+ neural stem cells in the adult hippocampus. Cell Stem Cell 2007; 1: 515-28.
14. Morshead CM, Reynolds BA, Craig CG, et al. Neural stem cells in the adult mammalian forebrain: a relatively quiescent subpopulation of subependymal cells. Neuron 1994; 13: 1071-82.
15. Yanamoto H, Miyamoto S, Tohnai N, et al. Induced spreading depression activates persistent neurogenesis in the subventricular zone, generating cells with markers for divided and early committed neurons in the caudate putamen and cortex. Stroke 2005; 36: 1544-50.
16. Nakagomi T, Taguchi A, Fujimori Y, et al. Isolation and characterization of neural stem/progenitor cells from post-stroke cerebral cortex in mice. Eur J Neurosci 2009; 29: 1842-52.
17. Nakayama D, Matsuyama T, Ishibashi-Ueda H, et al. Injuryinduced neural stem/progenitor cells in post-stroke human cerebral cortex. Eur J Neurosci 2010; 31: 90-8.
18. Arvidsson A, Collin T, Kirik D, et al. Neuronal replacement from endogenous precursors in the adult brain after stroke. Nat Med 2002; 8: 963-70.
19. Nakagomi N, Nakagomi T, Kubo S, et al. Endothelial cells support survival, proliferation, and neuronal differentiation of transplanted adult ischemia-induced neural stem/progenitor cells after cerebral infarction. Stem Cells 2009; 27: 2185-95.
20. Taguchi A, Soma T, Tanaka H, et al. Administration of CD34+ cells after stroke enhances neurogenesis via angiogenesis in a mouse model. J Clin Invest 2004; 114: 330-8.
21. Louissaint A, Jr., Rao S, Leventhal C, et al. Coordinated interaction of neurogenesis and angiogenesis in the adult songbird brain. Neuron 2002; 34: 945-60.
22. Sun J, Sha B, Zhou W, et al. VEGF-mediated angiogenesis stimulates neural stem cell proliferation and differentiation in the premature brain. Biochem Biophys Res Commun. 2010; 394: 146-52.
23. Taguchi A, Zhu P, Cao F, et al. Reduced ischemic brain injury by partial rejuvenation of bone marrow cells in aged rats. J Cereb Blood Flow Metab 2011; 31: 855-67.
24. Lambrechts D, Storkebaum E, Carmeliet P. VEGF: necessary to prevent motoneuron degeneration, sufficient to treat ALS? Trends Mol Med 2004; 10: 275-82.
25. Mizugishi K, Hatayama M, Tohmonda T, et al. Myogenic repressor I-mfa interferes with the function of Zic family proteins. Biochem Biophys Res Commun 2004; 320: 233-40.
26. Shin HY, Kim JH, Phi JH, et al. Endogenous neurogenesis and neovascularization in the neocortex of the rat after focal cerebral ischemia. J Neurosci Res 2008; 86: 356-67.
27. Hayashi T, Abe K, Itoyama Y. Reduction of ischemic damage by application of vascular endothelial growth factor in rat brain after transient ischemia. J Cereb Blood Flow Metab 1998; 18: 887-95.
28. Zhang ZG, Zhang L, Jiang Q, et al. VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain. J Clin Invest 2000; 106: 829-38.
29. Kawamoto A, Katayama M, Handa N, et al. Intramuscular transplantation of G-CSF-mobilized CD34(+) cells in patients with critical limb ischemia: a phase I/IIa, multicenter, single-blinded, doseescalation clinical trial. Stem Cells 2009; 27: 2857-64.
30. Kuethe F, Figulla HR, Voth M, et al. Mobilization of stem cells by granulocyte colony-stimulating factor for the regeneration of myocardial tissue after myocardial infarction. Dtsch Med Wochenschr 2004; 129: 424-8.
31. Gibson CL, Bath PM, Murphy SP. G-CSF administration is neuroprotective following transient cerebral ischemia even in the absence of a functional NOS-2 gene. J Cereb Blood Flow Metab 2010; 30: 739-43.
32. Taguchi A, Wen Z, Myojin K, et al. Granulocyte colonystimulating factor has a negative effect on stroke outcome in a murine model. Eur J Neurosci 2007; 26: 126-33.
33. Schabitz WR, Schwab S, Spranger M, et al. Intraventricular brainderived neurotrophic factor reduces infarct size after focal cerebral ischemia in rats. J Cereb Blood Flow Metab 1997; 17: 500-6.
34. Yanamoto H, Nagata I, Sakata M, et al. Infarct tolerance induced by intra-cerebral infusion of recombinant brain-derived neurotrophic factor. Brain Res 2000; 859: 240-8.
35. Kitagawa Y, Tanaka N, Hata Y, et al. Three-dimensional structure of Cu, Zn-superoxide dismutase from spinach at 2.0 A resolution. J Biochem 1991; 109: 477-85.
36. Yuen CM, Leu S, Lee FY, et al. Erythropoietin markedly attenuates brain infarct size and improves neurological function in the rat. J Investig Med 2010; 58: 893-904.
37. Asahara T, Murohara T, Sullivan A, et al. Isolation of putative progenitor endothelial cells for angiogenesis. Science1997; 275: 964-7.
38. Majka M, Janowska-Wieczorek A, Ratajczak J, et al. Numerous growth factors, cytokines, and chemokines are secreted by human CD34(+) cells, myeloblasts, erythroblasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner. Blood 2001; 97: 3075-85.
39. Taguchi A, Matsuyama T, Moriwaki H, et al. Circulating CD34-positive cells provide an index of cerebrovascular function. Circulation 2004; 109: 2972-5.
40. Taguchi A, Nakagomi N, Matsuyama T, et al. Circulating CD34-positive cells have prognostic value for neurologic function in patients with past cerebral infarction. J Cereb Blood Flow Metab 2009; 29: 34-8.
41. Taguchi A, Matsuyama T, Nakagomi T, et al. Circulating CD34-positive cells provide a marker of vascular risk associated with cognitive impairment. J Cereb Blood Flow Metab 2008; 28: 445-9.
42. Yoshihara T, Taguchi A, Matsuyama T, et al. Increase in circulating CD34-positive cells in patients with angiographic evidence of moyamoya-like vessels. J Cereb Blood Flow Metab 2008; 28: 1086-9.
43. Taguchi A, Kasahara Y, Nakagomi T, et al. A reproducible and simple model of permanent cerebral ischemia in CB-17 and SCID Mice. J Exp Stroke Transl Med 2010; 3: 28-33.