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Volumn 58, Issue 7, 2010, Pages 893-904

Erythropoietin markedly attenuates brain infarct size and improves neurological function in the rat

Author keywords

Acute ischemic stroke; EPO treatment

Indexed keywords

CASPASE 3; CHEMOKINE RECEPTOR CXCR4; DOUBLECORTIN; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERLEUKIN 18; MESSENGER RNA; PLASMINOGEN ACTIVATOR INHIBITOR; PROTEIN BAX; PROTEIN BCL 2; RECOMBINANT ERYTHROPOIETIN; STROMAL CELL DERIVED FACTOR 1; TOLL LIKE RECEPTOR 4; VON WILLEBRAND FACTOR; PLASMINOGEN ACTIVATOR INHIBITOR 1;

EID: 85008256418     PISSN: 17088267     EISSN: None     Source Type: Journal    
DOI: 10.2310/jim.0b013e3181e80c40     Document Type: Article
Times cited : (14)

References (38)
  • 1
    • 2342448263 scopus 로고    scopus 로고
    • American Heart Association, Dallas, TX: American Heart Association
    • American Heart Association. Stroke Statistics. Dallas, TX: American Heart Association; 2002.
    • (2002) Stroke Statistics
  • 2
    • 0032997755 scopus 로고    scopus 로고
    • Stroke: How large a public health problem, and how can the neurologist help?
    • Hankey GJ. Stroke: how large a public health problem, and how can the neurologist help? Arch Neurol. 1999;56:748-754.
    • (1999) Arch. Neurol. , vol.56 , pp. 748-754
    • Hankey, G.J.1
  • 3
    • 0003438833 scopus 로고    scopus 로고
    • World Health Organization, Geneva, Switzerland: World Health Organization
    • World Health Organization. World Health Report 1999-Making a Difference. Geneva, Switzerland: World Health Organization; 1999.
    • (1999) World Health Report 1999-making A Difference
  • 4
    • 0027514354 scopus 로고
    • Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment
    • Adams HP Jr, Bendixen BH, Kappelle LJ, et al. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke. 1993;24:35-41.
    • (1993) Stroke , vol.24 , pp. 35-41
    • Adams Jr., H.P.1    Bendixen, B.H.2    Kappelle, L.J.3
  • 5
    • 0034074730 scopus 로고    scopus 로고
    • Indications for early aspirin use in acute ischemic stroke: A combined analysis of 40 000 randomized patients from the Chinese Acute Stroke Trial and the International Stroke Trial
    • Chen Z, Sandercock P, Pan H, et al. Indications for early aspirin use in acute ischemic stroke: a combined analysis of 40 000 randomized patients from the Chinese Acute Stroke Trial and the International Stroke Trial. Stroke. 2000;31:1240-1249.
    • (2000) Stroke , vol.31 , pp. 1240-1249
    • Chen, Z.1    Sandercock, P.2    Pan, H.3
  • 6
    • 0035164329 scopus 로고    scopus 로고
    • Risk factors, outcome, and treatment in subtypes of ischemic stroke: The German stroke data bank
    • Grau AJ, Weimar C, Buggle F, et al. Risk factors, outcome, and treatment in subtypes of ischemic stroke: the German stroke data bank. Stroke. 2001;32:2559-2566.
    • (2001) Stroke , vol.32 , pp. 2559-2566
    • Grau, A.J.1    Weimar, C.2    Buggle, F.3
  • 7
    • 0029784380 scopus 로고    scopus 로고
    • Comparison of neurological scales and scoring systems for acute stroke prognosis
    • Muir KW, Weir CJ, Murray GD, et al. Comparison of neurological scales and scoring systems for acute stroke prognosis. Stroke. 1996;27:1817-1820.
    • (1996) Stroke , vol.27 , pp. 1817-1820
    • Muir, K.W.1    Weir, C.J.2    Murray, G.D.3
  • 8
    • 23844482259 scopus 로고    scopus 로고
    • Link between platelet activity and outcomes after an ischemic stroke
    • Yip HK, Liou CW, Chang HW, et al. Link between platelet activity and outcomes after an ischemic stroke. Cerebrovasc Dis. 2005;20:120-128.
    • (2005) Cerebrovasc Dis. , vol.20 , pp. 120-128
    • Yip, H.K.1    Liou, C.W.2    Chang, H.W.3
  • 9
    • 33846347159 scopus 로고    scopus 로고
    • Thrombolysis with alteplase for acute ischaemic stroke in the Safe Implementation of Thrombolysis in Stroke-monitoring Study (SITS-MOST): An observational study
    • Wahlgren N, Ahmed N, Davalos A, et al. Thrombolysis with alteplase for acute ischaemic stroke in the Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST): an observational study. Lancet. 2007;369:275-282.
    • (2007) Lancet , vol.369 , pp. 275-282
    • Wahlgren, N.1    Ahmed, N.2    Davalos, A.3
  • 11
    • 41249092747 scopus 로고    scopus 로고
    • Guidelines for the early management of adults with ischemic stroke: A guideline from the American Heart Association/American stroke association stroke council, clinical cardiology council, cardiovascular radiology and intervention council, and the atherosclerotic peripheral vascular disease and quality of care outcomes in research interdisciplinary working groups
    • Adams HP Jr, del Zoppo G, Alberts MJ, et al. Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: the American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists. Circulation. 2007;115: e478-e534.
    • (2007) Circulation , vol.115
    • Adams Jr., H.P.1    Del Zoppo, G.2    Alberts, M.J.3
  • 12
    • 17844407412 scopus 로고    scopus 로고
    • Intravenous thrombolysis in acute ischaemic stroke: Optimising its use in routine clinical practice
    • Bravata DM. Intravenous thrombolysis in acute ischaemic stroke: optimising its use in routine clinical practice. CNS Drugs. 2005;19:295-302.
    • (2005) CNS Drugs , vol.19 , pp. 295-302
    • Bravata, D.M.1
  • 13
    • 2542530145 scopus 로고    scopus 로고
    • Cost-effectiveness of thrombolysis with recombinant tissue plasminogen activator for acute ischemic stroke assessed by a model based on UK NHS costs
    • Sandercock P, Berge E, Dennis M, et al. Cost-effectiveness of thrombolysis with recombinant tissue plasminogen activator for acute ischemic stroke assessed by a model based on UK NHS costs. Stroke. 2004;35:1490-1497.
    • (2004) Stroke , vol.35 , pp. 1490-1497
    • Sandercock, P.1    Berge, E.2    Dennis, M.3
  • 14
    • 33846606371 scopus 로고    scopus 로고
    • Two tales: Hemorrhagic transformation but not parenchymal hemorrhage after thrombolysis is related to severity and duration of ischemia: MRI study of acute stroke patients treated with intravenous tissue plasminogen activator within 6 hours
    • Thomalla G, Sobesky J, Kohrmann M, et al. Two tales: hemorrhagic transformation but not parenchymal hemorrhage after thrombolysis is related to severity and duration of ischemia: MRI study of acute stroke patients treated with intravenous tissue plasminogen activator within 6 hours. Stroke. 2007;38:313-318.
    • (2007) Stroke , vol.38 , pp. 313-318
    • Thomalla, G.1    Sobesky, J.2    Kohrmann, M.3
  • 15
    • 0037447256 scopus 로고    scopus 로고
    • Recombinant human erythropoietin protects the myocardium from ischemia-reperfusion injury and promotes beneficial remodeling
    • Calvillo L, Latini R, Kajstura J, et al. Recombinant human erythropoietin protects the myocardium from ischemia-reperfusion injury and promotes beneficial remodeling. Proc Natl Acad Sci. 2003;100:4802-4806.
    • (2003) Proc. Natl. Acad. Sci. , vol.100 , pp. 4802-4806
    • Calvillo, L.1    Latini, R.2    Kajstura, J.3
  • 16
    • 33745250458 scopus 로고    scopus 로고
    • Erythropoietin enhances neovascularization of ischemic myocardium and improves left ventricular dysfunction after myocardial infarction in dogs
    • Hirata A, Minamino T, Asanuma H, et al. Erythropoietin enhances neovascularization of ischemic myocardium and improves left ventricular dysfunction after myocardial infarction in dogs. J Am Coll Cardiol. 2006;48:176-184.
    • (2006) J. Am. Coll. Cardiol. , vol.48 , pp. 176-184
    • Hirata, A.1    Minamino, T.2    Asanuma, H.3
  • 17
    • 0141593556 scopus 로고    scopus 로고
    • Erythropoietin reduces myocardial infarction and left ventricular functional decline after coronary artery ligation in rats
    • Moon C, Krawczyk M, Ahn D, et al. Erythropoietin reduces myocardial infarction and left ventricular functional decline after coronary artery ligation in rats. Proc Natl Acad Sci. 2003;100:11612-11617.
    • (2003) Proc. Natl. Acad. Sci. , vol.100 , pp. 11612-11617
    • Moon, C.1    Krawczyk, M.2    Ahn, D.3
  • 18
    • 0041659121 scopus 로고    scopus 로고
    • Erythropoietin protects cardiac myocytes from hypoxia-induced apoptosis through an Akt-dependent pathway
    • Tramontano AF, Muniyappa R, Black AD, et al. Erythropoietin protects cardiac myocytes from hypoxia-induced apoptosis through an Akt-dependent pathway. Biochem Biophys Res Commun. 2003;308:990-994.
    • (2003) Biochem. Biophys. Res. Commun. , vol.308 , pp. 990-994
    • Tramontano, A.F.1    Muniyappa, R.2    Black, A.D.3
  • 19
    • 0034641710 scopus 로고    scopus 로고
    • Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury
    • Brines ML, Ghezzi P, Keenan S, et al. Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury. Proc Natl Acad Sci. 2000;97:10526-10531.
    • (2000) Proc. Natl. Acad. Sci. , vol.97 , pp. 10526-10531
    • Brines, M.L.1    Ghezzi, P.2    Keenan, S.3
  • 20
    • 57049120087 scopus 로고    scopus 로고
    • Hypoxic preconditioning protects rat hearts against ischaemia-reperfusion injury: Role of erythropoietin on progenitor cell mobilization
    • Lin JS, Chen YS, Chiang HS, et al. Hypoxic preconditioning protects rat hearts against ischaemia-reperfusion injury: role of erythropoietin on progenitor cell mobilization. J Physiol. 2008;586:5757-5769.
    • (2008) J. Physiol. , vol.586 , pp. 5757-5769
    • Lin, J.S.1    Chen, Y.S.2    Chiang, H.S.3
  • 21
    • 4644227714 scopus 로고    scopus 로고
    • Timing of erythropoietin treatment for cardioprotection in ischemia/reperfusion
    • Lipsic E, van der Meer P, Henning RH, et al. Timing of erythropoietin treatment for cardioprotection in ischemia/reperfusion. J Cardiovasc Pharmacol. 2004;44:473-479.
    • (2004) J. Cardiovasc. Pharmacol. , vol.44 , pp. 473-479
    • Lipsic, E.1    Van Der Meer, P.2    Henning, R.H.3
  • 22
    • 1542286103 scopus 로고    scopus 로고
    • Erythropoietin in cardiovascular diseases
    • van der Meer P, Voors AA, Lipsic E, et al. Erythropoietin in cardiovascular diseases. Eur Heart J. 2004;25:285-291.
    • (2004) Eur. Heart J , vol.25 , pp. 285-291
    • Van Der Meer, P.1    Voors, A.A.2    Lipsic, E.3
  • 23
    • 0141784841 scopus 로고    scopus 로고
    • Erythropoietin selectively attenuates cytokine production and inflammation in cerebral ischemia by targeting neuronal apoptosis
    • Villa P, Bigini P, Mennini T, et al. Erythropoietin selectively attenuates cytokine production and inflammation in cerebral ischemia by targeting neuronal apoptosis. J Exp Med. 2003;198:971-975.
    • (2003) J. Exp. Med. , vol.198 , pp. 971-975
    • Villa, P.1    Bigini, P.2    Mennini, T.3
  • 24
    • 0035833541 scopus 로고    scopus 로고
    • Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades
    • Digicaylioglu M, Lipton SA. Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades. Nature. 2001;412:641-647.
    • (2001) Nature , vol.412 , pp. 641-647
    • Digicaylioglu, M.1    Lipton, S.A.2
  • 25
    • 0035914398 scopus 로고    scopus 로고
    • Erythropoietin receptor-mediated inhibition of exocytotic glutamate release confers neuroprotection during chemical ischemia
    • Kawakami M, Sekiguchi M, Sato K, et al. Erythropoietin receptor-mediated inhibition of exocytotic glutamate release confers neuroprotection during chemical ischemia. J Biol Chem. 2001;276:39469-39475.
    • (2001) J. Biol. Chem. , vol.276 , pp. 39469-39475
    • Kawakami, M.1    Sekiguchi, M.2    Sato, K.3
  • 26
    • 3042688444 scopus 로고    scopus 로고
    • Treatment of stroke with erythropoietin enhances neurogenesis and angiogenesis and improves neurological function in rats
    • Wang L, Zhang Z, Wang Y, et al. Treatment of stroke with erythropoietin enhances neurogenesis and angiogenesis and improves neurological function in rats. Stroke. 2004;35:1732-1737.
    • (2004) Stroke , vol.35 , pp. 1732-1737
    • Wang, L.1    Zhang, Z.2    Wang, Y.3
  • 27
    • 0036791849 scopus 로고    scopus 로고
    • Behavioral tests after intracerebral hemorrhage in rat
    • Hua Y, Schallert T, Keep RF, et al. Behavioral tests after intracerebral hemorrhage in rat. Stroke. 2002;33:2478-2484.
    • (2002) Stroke , vol.33 , pp. 2478-2484
    • Hua, Y.1    Schallert, T.2    Keep, R.F.3
  • 28
    • 33646117041 scopus 로고    scopus 로고
    • Erythroid cells play essential roles in angiogenesis by bone marrow cell implantation
    • Ozawa T, Toba K, Kato K, et al. Erythroid cells play essential roles in angiogenesis by bone marrow cell implantation. J Mol Cell Cardiol. 2006;40:629-638.
    • (2006) J. Mol. Cell. Cardiol. , vol.40 , pp. 629-638
    • Ozawa, T.1    Toba, K.2    Kato, K.3
  • 29
    • 33749452454 scopus 로고    scopus 로고
    • Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect
    • Bowie MB, McKnight KD, Kent DG, et al. Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect. J Clin Invest. 2006;116:2808-2816.
    • (2006) J. Clin. Invest. , vol.116 , pp. 2808-2816
    • Bowie, M.B.1    McKnight, K.D.2    Kent, D.G.3
  • 30
    • 23844513413 scopus 로고    scopus 로고
    • Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: Pivotal role of the SDF-1-CXCR4 axis
    • Kucia M, Reca R, Miekus K, et al. Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: pivotal role of the SDF-1-CXCR4 axis. Stem Cells. 2005;23:879-894.
    • (2005) Stem. Cells , vol.23 , pp. 879-894
    • Kucia, M.1    Reca, R.2    Miekus, K.3
  • 31
    • 36148997260 scopus 로고    scopus 로고
    • Cloning and expression pattern of dog SDF-1 and the implications of altered expression of SDF-1 in ischemic myocardium
    • Wei YJ, Tang Y, Li J, et al. Cloning and expression pattern of dog SDF-1 and the implications of altered expression of SDF-1 in ischemic myocardium. Cytokine. 2007;40:52-59.
    • (2007) Cytokine , vol.40 , pp. 52-59
    • Wei, Y.J.1    Tang, Y.2    Li, J.3
  • 32
    • 11144356195 scopus 로고    scopus 로고
    • Overexpression of CXCR4 on human CD34+ progenitors increases their proliferation, migration, and NOD/SCID repopulation
    • Kahn J, Byk T, Jansson-Sjostrand L, et al. Overexpression of CXCR4 on human CD34+ progenitors increases their proliferation, migration, and NOD/SCID repopulation. Blood. 2004;103:2942-2949.
    • (2004) Blood , vol.103 , pp. 2942-2949
    • Kahn, J.1    Byk, T.2    Jansson-Sjostrand, L.3
  • 33
    • 0037432293 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1 effects on ex vivo expanded endothelial progenitor cell recruitment for ischemic neovascularization
    • Yamaguchi J, Kusano KF, Masuo O, et al. Stromal cell-derived factor-1 effects on ex vivo expanded endothelial progenitor cell recruitment for ischemic neovascularization. Circulation. 2003;107:1322-1328.
    • (2003) Circulation , vol.107 , pp. 1322-1328
    • Yamaguchi, J.1    Kusano, K.F.2    Masuo, O.3
  • 34
    • 39149089319 scopus 로고    scopus 로고
    • Over-expression of CXCR4 on mesenchymal stem cells augments myoangiogenesis in the infarcted myocardium
    • Zhang D, Fan GC, Zhou X, et al. Over-expression of CXCR4 on mesenchymal stem cells augments myoangiogenesis in the infarcted myocardium. J Mol Cell Cardiol. 2008;44:281-292.
    • (2008) J. Mol. Cell. Cardiol. , vol.44 , pp. 281-292
    • Zhang, D.1    Fan, G.C.2    Zhou, X.3
  • 35
    • 9344255481 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1alpha plays a critical role in stem cell recruitment to the heart after myocardial infarction but is not sufficient to induce homing in the absence of injury
    • Abbott JD, Huang Y, Liu D, et al. Stromal cell-derived factor-1alpha plays a critical role in stem cell recruitment to the heart after myocardial infarction but is not sufficient to induce homing in the absence of injury. Circulation. 2004;110:3300-3305.
    • (2004) Circulation , vol.110 , pp. 3300-3305
    • Abbott, J.D.1    Huang, Y.2    Liu, D.3
  • 36
    • 34548174756 scopus 로고    scopus 로고
    • Stromal cell derived factor-1 alpha confers protection against myocardial ischemia/reperfusion injury: Role of the cardiac stromal cell derived factor-1 alpha CXCR4 axis
    • Hu X, Dai S, Wu WJ, et al. Stromal cell derived factor-1 alpha confers protection against myocardial ischemia/reperfusion injury: role of the cardiac stromal cell derived factor-1 alpha CXCR4 axis. Circulation. 2007;116:654-663.
    • (2007) Circulation , vol.116 , pp. 654-663
    • Hu, X.1    Dai, S.2    Wu, W.J.3
  • 37
    • 67650477577 scopus 로고    scopus 로고
    • Bone marrow-derived mononuclear cell therapy alleviates left ventricular remodeling and improves heart function in rat-dilated cardiomyopathy
    • Sun CK, Chang LT, Sheu JJ, et al. Bone marrow-derived mononuclear cell therapy alleviates left ventricular remodeling and improves heart function in rat-dilated cardiomyopathy. Crit Care Med. 2009;37:1197-1205.
    • (2009) Crit. Care Med. , vol.37 , pp. 1197-1205
    • Sun, C.K.1    Chang, L.T.2    Sheu, J.J.3
  • 38
    • 48749128239 scopus 로고    scopus 로고
    • Autologous bone marrow-derived mononuclear cell therapy prevents the damage of viable myocardium and improves rat heart function following acute anterior myocardial infarction
    • Yip H-K, Chang L-T, Wu C-J, et al. Autologous bone marrow-derived mononuclear cell therapy prevents the damage of viable myocardium and improves rat heart function following acute anterior myocardial infarction. Circulation J. 2008;72:1336-1345.
    • (2008) Circulation J , vol.72 , pp. 1336-1345
    • Yip, H.-K.1    Chang, L.-T.2    Wu, C.-J.3


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