Obesity and gastric cancer

Frontiers in Bioscience

Volumn 17, Issue 7, 2011, Pages 2383-2390

  Li, Qiang ^a   Zhang, Jun ^a   Zhou, Yongning ^a   Qiao, Liang ^b  

^a LANZHOU UNIVERSITY   (China)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Body mass index; Gastric cancer; Helicobacter pylori; Life style; Obesity; Review

Indexed keywords

ANIMALIA; HELICOBACTER PYLORI;

EID: 84860306579     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/4059     Document Type: Article

References (92)

1. World Health Organization, Obesity and overweight. http://www.who.int/ mediacentre/factsheets/fs311/en/index.html (2011)
2. Candib LM: Obesity and diabetes in vulnerable populations: reflection on proximal and distal causes. Ann Fam Med 5, 547-556 (2007) (Pubitemid 350248587)
3. Poirier P, Giles TD, Bray GA, Hong Y, Stern JS, Pi-Sunyer FX, Eckel RH: Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss. Arterioscler Thromb Vasc Biol 26, 968-976 (2006) (Pubitemid 43732100)
4. Lahmann PH, Gullberg B, Olsson H, Boeing H, Berglund G, Lissner L: Birth weight is associated with postmenopausal breast cancer risk in Swedish women. Br J Cancer 91, 1666-1668 (2004) (Pubitemid 39546139)
5. Kim Y, Kim Y, Lee S: An association between colonic adenoma and abdominal obesity: a crosssectional study. BMC Gastroenterol 9, 1-6 (2009)
6. Thomas JA 2nd, Freedland SJ: Obesity and prostate cancer: collateral damage in the battle of the bulge. Front Biosci (Schol Ed) 3, 594-605 (2011)
7. Mijovic T, How J, Payne RJ: Obesity and thyroid cancer. Front Biosci (Schol Ed) 3, 555-564 (2011)
8. Renehan AG, Tyson M, Egger M, Heller RF, Zwahlen M: Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies. Lancet 371, 569-578 (2008) (Pubitemid 351232031)
9. Calle EE, Kaaks R. Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms. Nat Rev Cancer 4, 579-591 (2004) (Pubitemid 39025053)
10. Fontaine KR, Redden DT, Wang C, Westfall AO, Allison DB: Years of life lost due to obesity. JAMA 289, 187-193 (2003) (Pubitemid 36068706)
11. Pan C, Yoo HJ, Ho LT: Perspectives of CB1 Antagonist in Treatment of Obesity: Experience of RIOAsia. J Obes 29, 1-11 (2010)
12. Flegal KM, Carroll MD, Ogden CL, Curtin LR: Prevalence and trends in obesity among US adults, 1999-2008. JAMA 303, 235-241 (2010)
13. Frieden TR; Centers for Disease Control and Prevention (CDC): Forward: CDC Health Disparities and Inequalities Report-United States, 2011. MMWR Surveill Summ 60, 1-2 (2011)
14. Yanovski SZ, Yanovski JA: Obesity prevalence in the United States-up, down, or sideways? N Engl J Med 364, 987-989 (2011)
15. Musingarimi P: Obesity in the UK: A review and comparative analysis of policies within the devolved administrations. Health Policy 91, 10-16 (2009)
16. Kim DM, Ahn CW, Nam SY: Prevalence of obesity in Korea. Obes Rev 6, 117-121 (2005)
17. Wu Y: Overweight and obesity in China. British Medical Journal 333, 362-363 (2006) (Pubitemid 44298059)
18. Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM: Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 127, 2893-2917 (2010)
19. Zhu HP, Xia X, Yu CH, Adnan A, Liu SF, Du YK: Application of Weibull model for survival of patients with gastric cancer. BMC Gastroenterol 11, 1-6 (2011)
20. Crew KD, Neugut AI: Epidemiology of gastric cancer. World J Gastroenterol 12, 354-362 (2006) (Pubitemid 43329250)
21. Ricci V, Romano M, Boquet P: Molecular cross-talk between Helicobacter pylori and human gastric mucosa. World J Gastroenterol 17, 1383-1399 (2011)
22. Yamamoto E, Suzuki H, Takamaru H, Yamamoto H, Toyota M, Shinomura Y: Role of DNA methylation in the development of diffuse-type gastric cancer. Digestion 83, 241-249 (2011)
23. Ryan AM, Rowley S, Fitzgerald AP, Ravi N, Reynolds JV: Adenocarcinoma of the oesophagus and gastric cardia: Male preponderance in association with obesity. Eur J Cancer 42, 1151-1158 (2006)
24. Campbell PT, Sloan M, Kreiger N: Dietary patterns and risk of incident gastric adenocarcinoma. Am J Epidemiol 167, 295-304 (2008) (Pubitemid 351197586)
25. Lindblad M, Rodríguez LA, Lagergren J: Body mass, tobacco and alcohol and risk of esophageal, gastric cardia, and gastric non-cardia adenocarcinoma among men and women in a nested case-control study. Cancer Causes Control 16, 285-294 (2005) (Pubitemid 40897847)
26. Jansson C, Johasson A, Nyrén O, Lagergren J: Socioeconomic factors and risk of esophageal adenocarcinoma: a nationwide Swedish case-control study. Cancer Epidemiol Biomarkers Prev 14, 1754-1761 (2005) (Pubitemid 40995091)
27. Zhang J, Su XQ, Wu XJ, Liu YH, Wang H, Zong XN, Wang Y, Ji JF: Effect of body mass index on adenocarcinoma of gastric cardia. World J Gastroentero 19, 2658-2661 (2003) (Pubitemid 38054434)
28. Corley DA, Kubo A: Influence of site classification on cancer incidence rates: an analysis of gastric cardia carcinomas. J Natl Cancer Inst 96, 1383-1387 (2004) (Pubitemid 39406172)
29. Kubo A, Corley DA: Body mass index and adenocarcinomas of the esophagus or gastric cardia: a systematic review and meta-analysis. Cancer Epidemiol Biomarkers Prev 15, 872-878 (2006) (Pubitemid 43823511)
30. Zhou Y, Zhang Z, Zhang Z, Wu J, Ren D, Yan X, Wang Q, Wang Y, Wang H, Zhang J, Zhu X, Yang Y, Luo C, Guo X, Tang C, Qiao L: A rising trend of gastric cardia cancer in Gansu Province of China. Cancer Lett 269, 18-25 (2008)
31. Merry AH, Schouten LJ, Goldbohm RA, van den Brandt PA: Body mass index, height and risk of adenocarcinoma of the oesophagus and gastric cardia: a prospective cohort study. Gut 56, 1503-1511 (2007) (Pubitemid 350033186)
32. Paz-Filho G, Lim EL, Wong ML, Licinio J: Associations between adipokines and obesity-related cancer. Front Biosci 16, 1634-1650 (2011)
33. Huang XF, Chen JZ: Obesity, the PI3K/Akt signal pathway and colon cancer. Obes Rev 6, 610-616 (2009)
34. Bai JG, Lv Y, Dang CX: Adenocarcinoma of the Esophagogastric Junction in China according to Siewert's classification. Jpn J Clin Oncol 36, 364-367 (2006) (Pubitemid 44043925)
35. Ji BT, Chow WH, Yang G, McLaughlin JK, Gao RN, Zheng W, Shu XO, Jin F, Fraumeni JF Jr, Gao YT: Body mass index and the risk of cancers of the gastric cardia and distal stomach in Shanghai, China. Cancer Epidemiol Biomarkers Prev 6, 481-485 (1997) (Pubitemid 27295225)
36. MacInnis RJ, English DR, Hopper JL, Giles GG: Body size and composition and the risk of gastric and oesophageal adenocarcinoma. Int J Cancer 118, 2628-2631 (2006)
37. Abnet CC, Freedman ND, Hollenbeck AR, Fraumeni JF Jr, Leitzmann M, Schatzkin A: A prospective study of BMI and risk of oesophageal and gastric adenocarcinoma. Eur J Cancer 44, 465-471 (2008)
38. Corley DA, Kubo A, Zhao W: Abdominal obesity and the risk of esophageal and gastric cardia carcinomas. Cancer Epidemiol Biomarkers Prev 17, 352-358 (2008) (Pubitemid 351272786)
39. Terry P, Lagergren J, Wolk A, Nyrén O: Refluxinducing dietary factors and risk of adenocarcinoma of the esophagus and gastric cardia. Nutr Cancer 38, 186-191 (2002)
40. Jacobson BC, Somers SC, Fuchs CS, Kelly CP, Camargo CA Jr: Body-mass index and symptoms of gastroesophageal reflux in women. N Engl J Med 354, 2340-2348 (2006) (Pubitemid 43801279)
41. Barak N, Ehrenpreis ED, Harrison JR, Sitrin MD: Gastro-oesophageal reflux disease in obesity: pathophysiological and therapeutic considerations. Obes Rev 3, 9-15 (2002) (Pubitemid 34827141)
42. Furuta T, Shirai N, Xiao F, Takashima M, Hanai H: Effect of Helicobacter pylori infection and its eradication on nutrition. Aliment Pharmacol Ther 16, 799-806 (2002) (Pubitemid 34407529)
43. Ishaq S, Jankowski JA: Barrett's metaplasia: clinical implications. World J Gastroenterol 7, 563-565 (2001) (Pubitemid 32780672)
44. Gupta K, Krishnaswamy G, Karnad A, Peiris AN: Insulin: a novel factor in carcinogenesis. Am J Med Sci 323, 140-145 (2002)
45. Chen J, Huang XF, Qiao L, Katsifis A: Insulin caused drug resistance to oxaliplatin in colon cancer cell line HT29.J Gastrointest Oncol 2: 27-33 (2011)
46. Renehan AG, Zwahlen M, Minder C, O'Dwyer ST, Shalet SM, Egger M: Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis. Lancet 363, 1346-1353 (2004) (Pubitemid 38529873)
47. Khandwala HM, McCutcheon IE, Flyvbjerg A, Friend KE: The effects of insulin-like growth factors on tumorigenesis and neoplastic growth. Endocr Rev 21, 215-244 (2000) (Pubitemid 32275588)
48. Terry KL, Tworoger SS, Gates MA, Cramer DW, Hankinson SE: Common genetic variation in IGF1, IGFBP1 and IGFBP3 and ovarian cancer risk. Carcinogenesis 30, 2042-2046 (2009)
49. Kim WY, Jin Q, Oh SH, Kim ES, Yang YJ, Lee DH, Feng L, Behrens C, Prudkin L, Miller YE, Lee JJ, Lippman SM, Hong WK, Wistuba II, Lee HY: Elevated epithelial insulin-like growth factor expression is a risk factor for lung cancer development. Cancer Res 69, 7439-7448 (2009)
50. Lima GA, Corrêa LL, Gabrich R, Miranda LC, Gadelha MR: IGF-I, insulin and prostate cancer. Arq Bras Endocrinol Metabol 53, 969-975 (2009)
51. Fürstenberger G, Senn HJ: Insulin-like growth factors and cancer. Lancet Oncol 3, 298-302 (2002) (Pubitemid 34546447)
52. Seker M, Bilici A, Sonmez B, Ustaalioǧlu BB, Gumus M, Gozu H, Sargin M, Orcun A, Gezen C, Eser M, Bildik N, Salepci T: The association of serum adiponectin levels with histopathological variables in gastric cancer patients. Med Oncol 27, 1319-1323 (2010)
53. Otake S, Takeda H, Fujishima S, Fukui T, Orii T, Sato T, Sasaki Y, Nishise S, Kawata S: Decreased levels of plasma adiponectin associated with increased risk of colorectal cancer. World J Gastroenterol 16, 1252-1257 (2010)
54. Miyoshi Y, Funahashi T, Kihara S, Taguchi T, Tamaki Y, Matsuzawa Y, Noguchi S: Association of serum adiponectin levels with breast cancer risk. Clin Cancer Res 9, 5699-5704 (2003) (Pubitemid 37499493)
55. Wang Y, Lam JB, Lam KS, Liu J, Lam MC, Hoo RL, Wu D, Cooper GJ, Xu A: Adiponectin modulates the glycogen synthase kinase-3beta/beta-catenin signaling pathway and attenuates mammary tumorigenesis of MDA-MB-231 cells in nude mice. Cancer Res 66, 11462-11470 (2006) (Pubitemid 46009979)
56. Ishikawa M, Kitayama J, Kazama S, Hiramatsu T, Hatano K, Nagawa H: Plasma adiponectin and gastric cancer. Clin Cancer Res 11, 466-472 (2005) (Pubitemid 40116868)
57. Ishikawa M, Kitayama J, Yamauchi T, Kadowaki T, Maki T, Miyato H, Yamashita H, Nagawa H: Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specific membrane receptors AdipoR1 and AdipoR2. Cancer Sci 98, 1120-1127 (2007) (Pubitemid 46865400)
58. Otani K, Kitayama J, Kamei T, Soma D, Miyato H, Yamauchi T, Kadowaki T, Nagawa H: Adiponectin receptors are downregulated in human gastric cancer. J Gastroenterol 45, 918-927 (2010)
59. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM: Positional cloning of the mouse obese gene and its human homologue. Nature 372, 425-432 (1994) (Pubitemid 24365442)
60. Paz-Filho G, Wong ML, Licinio J: Ten years of leptin replacement therapy. Obes Rev 12, e315-323 (2011)
61. Maffei M, Halaas J, Ravussin E, Pratley RE, Lee GH, Zhang Y, Fei H, Kim S, Lallone R, Ranganathan S: Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med 1, 1155-1161 (1995)
62. Ceddia RB, Koistinen HA, Zierath JR, Sweeney G: Analysis of paradoxical observations on the association between leptin and insulin resistance. FASEB J 16, 1163-1176 (2002) (Pubitemid 34815404)
63. Filho G, Lim EL, Wong ML, Licinio J. Associations between adipokines and obesity-related cancer. Front Biosci 16, 1634-50 (2011)
64. Howard JM, Pidgeon GP, Reynolds JV. Leptin and gastro-intestinal malignancies. Obes Rev 11, 863-74 (2010)
65. Friedman JM: Leptin and the regulation of body weigh. Keio J Med 60, 1-9 (2011)
66. Zhao L, Shen ZX, Luo HS, Luo HS, Shen L: Possible involvement of leptin and leptin receptor in developing gastric adenocarcinoma. World J Gastroenterol 11, 7666-7670 (2005) (Pubitemid 43168434)
67. Ishikawa M, Kitayama J, Nagawa H: Expression pattern of leptin and leptin receptor (OB-R) in human gastric cancer. World J Gastroenterol 12, 5517-5522 (2006) (Pubitemid 44501812)
68. Mix H, Widjaja A, Jandl O, Cornberg M, Kaul A, Göke M, Beil W, Kuske M, Brabant G, Manns MP, Wagner S: Expression of leptin and leptin receptor isoforms in the human stomach. Gut 47, 481-486 (2000)
69. Yudkin JS: Adipose tissue, insulin action and vascular disease: inflammatory signals. Int J Obes Relat Metab Disord 27, 25-28 (2003)
70. Heikkilä K, Harris R, Lowe G, Rumley A, Yarnell J, Gallacher J, Ben-Shlomo Y, Ebrahim S, Lawlor DA: Associations of circulating C-reactive protein and interleukin-6 with cancer risk: findings from two prospective cohorts and a meta-analysis. Cancer Causes Control 20, 15-26 (2009)
71. Wu Y, Zhou BP: TNF-alpha/NF-kappaB/Snail pathway in cancer cell migration and invasion. Br J Cancer 102, 639-644 (2010)
72. Naugler WE, Sakurai T, Kim S, Maeda S, Kim K, Elsharkawy AM, Karin M: Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production. Science 317, 121-124 (2007) (Pubitemid 47056470)
73. Galgani M, Matarese G: Editorial: acute inflammation in obesity: IL-17A in the middle of the battle. J Leukoc Biol 87, 17-18 (2010)
74. Stamenkovic-Pejkovic D, Starcevic V, Trajkovic V, Micic D. Increased activity of interleukin-23/interleukin-17 proinflammatory axis in obese women. Int J Obes (Lond) 33, 151-156 (2009)
75. Gislette T, Chen J: The possible role of IL-17 in obesity-associated cancer. TheScientificWorldJOURNAL 16, 2265-2271(2010)
76. Canedo P, Durães C, Pereira F, Regalo G, Lunet N, Barros H, Carneiro F, Seruca R, Rocha J, Machado JC: Tumor necrosis factor alpha extended haplotypes and risk of gastric carcinoma. Cancer Epidemiol Biomarkers Prev 17, 2416-2420 (2008)
77. Kai H, Kitadai Y, Kodama M, Cho S, Kuroda T, Ito M, Tanaka S, Ohmoto Y, Chayama K: Involvement of proinflammatory cytokines IL-1beta and IL-6 in progression of human gastric carcinoma. Anticancer Res 25, 709-713 (2005) (Pubitemid 40546835)
78. Kuroda T, Kitadai Y, Tanaka S, Yang X, Mukaida N, Yoshihara M, Chayama K: Monocyte chemoattractant protein-1 transfection induces angiogenesis and tumorigenesis of gastric carcinoma in nude mice via macrophage recruitment. Clin Cancer Res 11, 7629-7636 (2005) (Pubitemid 41611603)
79. Chen J: The IL-23/IL-17 axis may be important in obesityassociated cancer by way of the activation of multiple signal pathways. Int J Obes (Lond) 34, 1227-1228 (2010)
80. Bodger K, Bromelow K, Wyatt JI, Heatley RV: Interleukin 10 in Helicobacter pylori associated gastritis: immunohistochemical localisation and in vitro effects on cytokine secretion. J Clin Pathol 54, 285-292 (2001) (Pubitemid 32270011)
81. Chung HY, Cha B, Kim H: Inhibition of serine-threonine protein phosphatases in monocyte chemoattractant protein-1 expression in Helicobacter pylori-stimulated gastric epithelial cells. Ann N Y Acad Sci 1095, 220-227 (2007) (Pubitemid 47092454)
82. Sheh A, Lee CW, Masumura K, Rickman BH, Nohmi T, Wogan GN, Fox JG, Schauer DB: Mutagenic potency of Helicobacter pylori in the gastric mucosa of mice is determined by sex and duration of infection. Proc Natl Acad Sci U S A 107, 15217-15222 (2010)
83. Maeda S, Mentis AF: Pathogenesis of Helicobacter pylori infection. Helicobacter 12, 10-14 (2007) (Pubitemid 47312373)
84. Salih BA: Helicobacter pylori infection in developing countries: the burden for how long? Saudi J Gastroenterol 15, 201-207 (2009)
85. Wu MS, Lee WJ, Wang HH, Huang SP, Lin JT: A casecontrol study of association of Helicobacter pylori infection with morbid obesity in Taiwan. Arch Intern Med 165, 1552-1555 (2005)
86. Arslan E, Atilgan H, Yavaşoǧlu I: The prevalence of Helicobacter pylori in obese subjects. Eur J Intern Med 20, 695-697 (2009)
87. Loffeld RJ: Helicobacter pylori, obesity and gastrooesophageal reflux disease. Is there a relation? A personal view. Neth J Med 63, 344-347 (2005) (Pubitemid 41748588)
88. Francois F, Roper J, Joseph N, Pei Z, Chhada A, Shak JR, de Perez AZ, Perez-Perez GI, Blaser MJ: The effect of H. pylori eradication on meal-associated changes in plasma ghrelin and leptin. BMC Gastroenterol 11, 1-9 (2011)
89. Higgins SC, Gueorguiev M, Korbonits M: Ghrelin, the peripheral hunger hormone. Ann Med 39, 116-136 (2007) (Pubitemid 46598179)
90. Murphy G, Kamangar F, Dawsey SM, Stanczyk FZ, Weinstein SJ, Taylor PR, Virtamo J, Abnet CC, Albanes D, Freedman ND: The relationship between serum ghrelin and the risk of gastric and esophagogastric junctional adenocarcinomas. J Natl Cancer Inst 103, 1123-1129 (2011)
91. Dixit VD, Schaffer EM, Pyle RS, Collins GD, Sakthivel SK, Palaniappan R, Lillard JW Jr, Taub DD: Ghrelin inhibits leptin-and activation-induced proinflammatory cytokine expression by human monocytes and T cells. J Clin Invest 114, 57-66 (2004) (Pubitemid 39071644)
92. Isomoto H, Ueno H, Saenko VA, Mondal MS, Nishi Y, Kawano N, Ohnita K, Mizuta Y, Ohtsuru A, Yamashita S, Nakazato M, Kohno S: Impact of Helicobacter pylori infection on gastric and plasma ghrelin dynamics in humans. Am J Gastroenterol 100, 1711-1720 (2005) (Pubitemid 41648423)