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Volumn 83, Issue 4, 2011, Pages 241-249

Role of DNA methylation in the development of diffuse-type gastric cancer

Author keywords

Diffuse type gastric cancer; DNA methylation; Epstein Barr virus; Helicobacter pylori

Indexed keywords

UVOMORULIN;

EID: 79151478956     PISSN: 00122823     EISSN: None     Source Type: Journal    
DOI: 10.1159/000320453     Document Type: Article
Times cited : (60)

References (80)
  • 3
    • 0042886962 scopus 로고    scopus 로고
    • Control of gut differentiation and intestinal-type gastric carcinogenesis
    • DOI 10.1038/nrc1141
    • Yuasa Y: Control of gut differentiation and intestinal-type gastric carcinogenesis. Nat Rev Cancer 2003; 3: 592-600. (Pubitemid 37328831)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.8 , pp. 592-600
    • Yuasa, Y.1
  • 4
    • 0032148121 scopus 로고    scopus 로고
    • Helicobacter pylori infection and gastric neoplasia: Correlations with histological gastritis and tumor histology
    • DOI 10.1111/j.1572-0241.1998.00408.x, PII S0002927098002895
    • Komoto K, Haruma K, Kamada T, Tanaka S, Yoshihara M, Sumii K, Kajiyama G, Talley NJ: Helicobacter pylori infection and gastric neoplasia: correlations with histological gastritis and tumor histology. Am J Gastroenterol 1998; 93: 1271-1276. (Pubitemid 29076926)
    • (1998) American Journal of Gastroenterology , vol.93 , Issue.8 , pp. 1271-1276
    • Komoto, K.1    Haruma, K.2    Kamada, T.3    Tanaka, S.4    Yoshihara, M.5    Sumii, K.6    Kajiyama, G.7    Talley, N.J.8
  • 6
    • 0029113003 scopus 로고
    • The sequential accumulation of genetic alterations characteristic of the colorectal adenoma- carcinoma sequence does not occur between gastric adenoma and adenocarcinoma
    • Maesawa C, Tamura G, Suzuki Y, Ogasawara S, Sakata K, Kashiwaba M, Satodate R: The sequential accumulation of genetic alterations characteristic of the colorectal adenoma- carcinoma sequence does not occur between gastric adenoma and adenocarcinoma. J Pathol 1995; 176: 249-258.
    • (1995) J Pathol , vol.176 , pp. 249-258
    • Maesawa, C.1    Tamura, G.2    Suzuki, Y.3    Ogasawara, S.4    Sakata, K.5    Kashiwaba, M.6    Satodate, R.7
  • 12
    • 1442310498 scopus 로고    scopus 로고
    • Focus on gastric cancer
    • DOI 10.1016/S1535-6108(04)00033-9, PII S1535610804000339
    • Ushijima T, Sasako M: Focus on gastric cancer. Cancer Cell 2004; 5: 121-125. (Pubitemid 38283798)
    • (2004) Cancer Cell , vol.5 , Issue.2 , pp. 121-125
    • Ushijima, T.1    Sasako, M.2
  • 13
    • 33847065486 scopus 로고    scopus 로고
    • The Epigenomics of Cancer
    • DOI 10.1016/j.cell.2007.01.029, PII S0092867407001274
    • Jones PA, Baylin SB: The epigenomics of cancer. Cell 2007; 128: 683-692. (Pubitemid 46273572)
    • (2007) Cell , vol.128 , Issue.4 , pp. 683-692
    • Jones, P.A.1    Baylin, S.B.2
  • 14
    • 25844530426 scopus 로고    scopus 로고
    • Epigenetic changes in solid and hematopoietic tumors
    • Toyota M, Issa JP: Epigenetic changes in solid and hematopoietic tumors. Semin Oncol 2005; 32: 521-530.
    • (2005) Semin Oncol , vol.32 , pp. 521-530
    • Toyota, M.1    Issa, J.P.2
  • 15
    • 20044369539 scopus 로고    scopus 로고
    • Aberrant methylations in cancer cells: Where do they come from?
    • DOI 10.1111/j.1349-7006.2005.00035.x
    • Ushijima T, Okochi-Takada E: Aberrant methylations in cancer cells: where do they come from? Cancer Sci 2005; 96: 206-211. (Pubitemid 40767056)
    • (2005) Cancer Science , vol.96 , Issue.4 , pp. 206-211
    • Ushijima, T.1    Okochi-Takada, E.2
  • 17
    • 0032848687 scopus 로고    scopus 로고
    • Distinct methylation pattern and microsatellite instability in sporadic gastric cancer
    • DOI 10.1002/(SICI)1097-0215(19991029)83:3<309::AID-IJC4>3.0.CO;2-Z
    • Suzuki H, Itoh F, Toyota M, Kikuchi T, Kakiuchi H, Hinoda Y, Imai K: Distinct methylation pattern and microsatellite instability in sporadic gastric cancer. Int J Cancer 1999; 83: 309-313. (Pubitemid 29455752)
    • (1999) International Journal of Cancer , vol.83 , Issue.3 , pp. 309-313
    • Suzuki, H.1    Itoh, F.2    Toyota, M.3    Kikuchi, T.4    Kakiuchi, H.5    Hinoda, Y.6    Imai, K.7
  • 18
    • 0033804078 scopus 로고    scopus 로고
    • Microsatellite alterations in differentiated-type adenocarcinomas and precancerous lesions of the stomach with special reference to cellular phenotype
    • Ohmura K, Tamura G, Endoh Y, Sakata K, Takahashi T, Motoyama T: Microsatellite alterations in differentiated-type adenocarcinomas and precancerous lesions of the stomach with special reference to cellular phenotype. Hum Pathol 2000; 31: 1031-1035.
    • (2000) Hum Pathol , vol.31 , pp. 1031-1035
    • Ohmura, K.1    Tamura, G.2    Endoh, Y.3    Sakata, K.4    Takahashi, T.5    Motoyama, T.6
  • 19
    • 33644757018 scopus 로고    scopus 로고
    • Alterations of tumor suppressor and tumor-related genes in the development and progression of gastric cancer
    • Tamura G: Alterations of tumor suppressor and tumor-related genes in the development and progression of gastric cancer. World J Gastroenterol 2006; 12: 192-198. (Pubitemid 43336916)
    • (2006) World Journal of Gastroenterology , vol.12 , Issue.2 , pp. 192-198
    • Tamura, G.1
  • 20
  • 21
    • 0036966214 scopus 로고    scopus 로고
    • Promoter methylation status of E-cadherin, hMLH1, and p16 genes in nonneoplastic gastric epithelia
    • Waki T, Tamura G, Tsuchiya T, Sato K, Nishizuka S, Motoyama T: Promoter methylation status of E-cadherin, hMLH1, and p16 genes in non-neoplastic gastric epithelia. Am J Pathol 2002; 161: 399-403. (Pubitemid 36142148)
    • (2002) American Journal of Pathology , vol.161 , Issue.2 , pp. 399-403
    • Waki, T.1    Tamura, G.2    Tsuchiya, T.3    Sato, K.4    Nishizuka, S.5    Motoyama, T.6
  • 23
    • 0141537154 scopus 로고    scopus 로고
    • Aberrant CpG island hypermethylation of chronic gastritis, in relation to aging, gender, intestinal metaplasia, and chronic inflammation
    • Kang GH, Lee HJ, Hwang KS, Lee S, Kim JH, Kim JS: Aberrant CpG island hypermethylation of chronic gastritis, in relation to aging, gender, intestinal metaplasia, and chronic inflammation. Am J Pathol 2003; 163: 1551-1556. (Pubitemid 37175101)
    • (2003) American Journal of Pathology , vol.163 , Issue.4 , pp. 1551-1556
    • Kang, G.H.1    Lee, H.J.2    Hwang, K.S.3    Lee, S.4    Kim, J.-H.5    Kim, J.-S.6
  • 26
    • 28344433041 scopus 로고    scopus 로고
    • Frequent epigenetic inactivation of Wnt inhibitory factor-1 in human gastrointestinal cancers
    • DOI 10.1038/sj.onc.1208910, PII 1208910
    • Taniguchi H, Yamamoto H, Hirata T, Miyamoto N, Oki M, Nosho K, Adachi Y, Endo T, Imai K, Shinomura Y: Frequent epigenetic inactivation of Wnt inhibitory factor-1 in human gastrointestinal cancers. Oncogene 2005; 24: 7946-7952. (Pubitemid 41715201)
    • (2005) Oncogene , vol.24 , Issue.53 , pp. 7946-7952
    • Taniguchi, H.1    Yamamoto, H.2    Hirata, T.3    Miyamoto, N.4    Oki, M.5    Nosho, K.6    Adachi, Y.7    Endo, T.8    Imai, K.9    Shinomura, Y.10
  • 29
    • 33645801603 scopus 로고    scopus 로고
    • Genetic, epigenetic, and clinicopathologic features of gastric carcinomas with the CpG island methylator phenotype and an association with Epstein-Barr virus
    • Kusano M, Toyota M, Suzuki H, Akino K, Aoki F, Fujita M, Hosokawa M, Shinomura Y, Imai K, Tokino T: Genetic, epigenetic, and clinicopathologic features of gastric carcinomas with the CpG island methylator phenotype and an association with Epstein-Barr virus. Cancer 2006; 106: 1467-1479.
    • (2006) Cancer , vol.106 , pp. 1467-1479
    • Kusano, M.1    Toyota, M.2    Suzuki, H.3    Akino, K.4    Aoki, F.5    Fujita, M.6    Hosokawa, M.7    Shinomura, Y.8    Imai, K.9    Tokino, T.10
  • 31
    • 35548932394 scopus 로고    scopus 로고
    • E-cadherin and hereditary diffuse gastric cancer
    • DOI 10.1016/j.surg.2007.06.006, PII S0039606007003650
    • Pedrazzani C, Corso G, Marrelli D, Roviello F: E-cadherin and hereditary diffuse gastric cancer. Surgery 2007; 142: 645-657. (Pubitemid 350018845)
    • (2007) Surgery , vol.142 , Issue.5 , pp. 645-657
    • Pedrazzani, C.1    Corso, G.2    Marrelli, D.3    Roviello, F.4
  • 32
    • 53949103559 scopus 로고    scopus 로고
    • Hereditary diffuse gastric cancer: Implications of genetic testing for screening and prophylactic surgery
    • Cisco RM, Ford JM, Norton JA: Hereditary diffuse gastric cancer: implications of genetic testing for screening and prophylactic surgery. Cancer 2008; 113(suppl):1850-1856.
    • (2008) Cancer , vol.113 , Issue.SUPPL. , pp. 1850-1856
    • Cisco, R.M.1    Ford, J.M.2    Norton, J.A.3
  • 33
    • 0035211026 scopus 로고    scopus 로고
    • Incidence of gastric cancer and breast cancer in CDH1 (E-cadherin) mutation carriers from hereditary diffuse gastric cancer families
    • Pharoah PD, Guilford P, Caldas C: International Gastric Cancer Linkage Consortium. Incidence of gastric cancer and breast cancer in CDH1 (E-cadherin) mutation carriers from hereditary diffuse gastric cancer families. Gastroenterology 2001; 121: 1348-1353. (Pubitemid 33140452)
    • (2001) Gastroenterology , vol.121 , Issue.6 , pp. 1348-1353
    • Pharoah, P.D.P.1    Guilford, P.2    Caldas, C.3
  • 34
    • 56749176437 scopus 로고    scopus 로고
    • Cadherins and cancer: How does cadherin dysfunction promote tumor progression?
    • Jeanes A, Gottardi CJ, Yap AS: Cadherins and cancer: how does cadherin dysfunction promote tumor progression? Oncogene 2008; 27: 6920-6929.
    • (2008) Oncogene , vol.27 , pp. 6920-6929
    • Jeanes, A.1    Gottardi, C.J.2    Yap, A.S.3
  • 35
    • 38449100410 scopus 로고    scopus 로고
    • Molecular pathology of familial gastric cancer, with an emphasis on hereditary diffuse gastric cancer
    • DOI 10.1136/jcp.2006.043679
    • Carneiro F, Oliveira C, Suriano G, Seruca R: Molecular pathology of familial gastric cancer, with an emphasis on hereditary diffuse gastric cancer. J Clin Pathol 2008; 61: 25-30. (Pubitemid 351158221)
    • (2008) Journal of Clinical Pathology , vol.61 , Issue.1 , pp. 25-30
    • Carneiro, F.1    Oliveira, C.2    Suriano, G.3    Seruca, R.4
  • 39
    • 40149083881 scopus 로고    scopus 로고
    • Endogastric capsule for E-cadherin gene (CDH1) promoter hypermethylation assessment in DNA from gastric juice of diffuse gastric cancer patients
    • DOI 10.1093/annonc/mdm493
    • Muretto P, Ruzzo A, Pizzagalli F, Graziano F, Maltese P, Zingaretti C, Berselli E, Donnarumma N, Magnani M: Endogastric capsule for E-cadherin gene (CDH1) promoter hypermethylation assessment in DNA from gastric juice of diffuse gastric cancer patients. Ann Oncol 2008; 19: 516-519. (Pubitemid 351325673)
    • (2008) Annals of Oncology , vol.19 , Issue.3 , pp. 516-519
    • Muretto, P.1    Ruzzo, A.2    Pizzagalli, F.3    Graziano, F.4    Maltese, P.5    Zingaretti, C.6    Berselli, E.7    Donnarumma, N.8    Magnani, M.9
  • 40
    • 1042301963 scopus 로고    scopus 로고
    • Epstein-Barr Virus and Cancer
    • DOI 10.1158/1078-0432.CCR-0670-3
    • Thompson MP, Kurzrock R: Epstein-Barr virus and cancer. Clin Cancer Res 2004; 10: 803-821. (Pubitemid 38198878)
    • (2004) Clinical Cancer Research , vol.10 , Issue.3 , pp. 803-821
    • Thompson, M.P.1    Kurzrock, R.2
  • 41
    • 50149120544 scopus 로고    scopus 로고
    • Epstein- Barr virus and gastric carcinoma: Virus-host interactions leading to carcinoma
    • Fukayama M, Hino R, Uozaki H: Epstein- Barr virus and gastric carcinoma: virus-host interactions leading to carcinoma. Cancer Sci 2008; 99: 1726-1733.
    • (2008) Cancer Sci , vol.99 , pp. 1726-1733
    • Fukayama, M.1    Hino, R.2    Uozaki, H.3
  • 42
    • 38949215436 scopus 로고    scopus 로고
    • Epstein-Barr virus associated gastric carcinoma: Epidemiological and clinicopathological features
    • DOI 10.1111/j.1349-7006.2007.00674.x
    • Akiba S, Koriyama C, Herrera-Goepfert R, Eizuru Y: Epstein-Barr virus associated gastric carcinoma: epidemiological and clinicopathological features. Cancer Sci 2008; 99: 195-201. (Pubitemid 351228470)
    • (2008) Cancer Science , vol.99 , Issue.2 , pp. 195-201
    • Akiba, S.1    Koriyama, C.2    Herrera-Goepfert, R.3    Eizuru, Y.4
  • 43
    • 50149086269 scopus 로고    scopus 로고
    • Epstein-Barr virus and gastric carcinoma - Viral carcinogenesis through epigenetic mechanisms
    • Uozaki H, Fukayama M: Epstein-Barr virus and gastric carcinoma - viral carcinogenesis through epigenetic mechanisms. Int J Clin Exp Pathol 2008; 1: 198-216.
    • (2008) Int J Clin Exp Pathol , vol.1 , pp. 198-216
    • Uozaki, H.1    Fukayama, M.2
  • 44
    • 0025422532 scopus 로고
    • Lymphoepithelial carcinoma of the stomach with Epstein-Barr virus demonstrated by polymerase chain reaction
    • Burke AP, Yen TS, Shekitka KM, Sobin LH: Lymphoepithelial carcinoma of the stomach with Epstein-Barr virus demonstrated by polymerase chain reaction. Mod Pathol 1990; 3: 377-380.
    • (1990) Mod Pathol , vol.3 , pp. 377-380
    • Burke, A.P.1    Yen, T.S.2    Shekitka, K.M.3    Sobin, L.H.4
  • 46
    • 0036121312 scopus 로고    scopus 로고
    • Epstein-Barr virus-positive gastric carcinoma demonstrates frequent aberrant methylation of multiple genes and constitutes CpG island methylator phenotype-positive gastric carcinoma
    • Kang GH, Lee S, Kim WH, Lee HW, Kim JC, Rhyu MG, Ro JY: Epstein-Barr virus-positive gastric carcinoma demonstrates frequent aberrant methylation of multiple genes and constitutes CpG island methylator phenotype-positive gastric carcinoma. Am J Pathol 2002; 160: 787-794. (Pubitemid 34224568)
    • (2002) American Journal of Pathology , vol.160 , Issue.3 , pp. 787-794
    • Kang, G.H.1    Lee, S.2    Kim, W.H.3    Lee, H.W.4    Kim, J.C.5    Rhyu, M.-G.6    Ro, J.Y.7
  • 51
    • 0141867776 scopus 로고    scopus 로고
    • Detection of Epstein-Barr virus in gastric carcinoma cells and surrounding lymphocytes
    • DOI 10.1007/s10120-003-0247-2
    • Oda K, Koda K, Takiguchi N, Nunomura M, Seike K, Miyazaki M: Detection of Epstein- Barr virus in gastric carcinoma cells and surrounding lymphocytes. Gastric Cancer 2003; 6: 173-178. (Pubitemid 37221568)
    • (2003) Gastric Cancer , vol.6 , Issue.3 , pp. 173-178
    • Oda, K.1    Koda, K.2    Takiguchi, N.3    Nunomura, M.4    Seike, K.5    Miyazaki, M.6
  • 54
    • 33646268625 scopus 로고    scopus 로고
    • Mechanisms inactivating the gene for E-cadherin in sporadic gastric carcinomas
    • Chen TW, Hsu HM: Mechanisms inactivating the gene for E-cadherin in sporadic gastric carcinomas. World J Gastroenterol 2006; 12: 2168-2173.
    • (2006) World J Gastroenterol , vol.12 , pp. 2168-2173
    • Chen, T.W.1    Hsu, H.M.2
  • 55
    • 0038339107 scopus 로고    scopus 로고
    • Age-related methylation of tumor suppressor and tumor-related genes: An analysis of autopsy samples
    • DOI 10.1038/sj.onc.1206651
    • Waki T, Tamura G, Sato M, Motoyama T: Age-related methylation of tumor suppressor and tumor-related genes: an analysis of autopsy samples. Oncogene 2003; 22: 4128-4133. (Pubitemid 36819653)
    • (2003) Oncogene , vol.22 , Issue.26 , pp. 4128-4133
    • Waki, T.1    Tamura, G.2    Sato, M.3    Motoyama, T.4
  • 56
    • 76649145629 scopus 로고    scopus 로고
    • Inflammatory processes triggered by Helicobacter pylori infection cause aberrant DNA methylation in gastric epithelial cells
    • Niwa T, Tsukamoto T, Toyoda T, Mori A, Tanaka H, Maekita T, Ichinose M, Tatematsu M, Ushijima T: Inflammatory processes triggered by Helicobacter pylori infection cause aberrant DNA methylation in gastric epithelial cells. Cancer Res 2010; 70: 1430-1440.
    • (2010) Cancer Res , vol.70 , pp. 1430-1440
    • Niwa, T.1    Tsukamoto, T.2    Toyoda, T.3    Mori, A.4    Tanaka, H.5    Maekita, T.6    Ichinose, M.7    Tatematsu, M.8    Ushijima, T.9
  • 57
    • 33748939095 scopus 로고    scopus 로고
    • Multiple tumor suppressor genes are increasingly methylated with age in non-neoplastic gastric epithelia
    • DOI 10.1111/j.1349-7006.2006.00302.x
    • So K, Tamura G, Honda T, Homma N, Waki T, Togawa N, Nishizuka S, Motoyama T: Multiple tumor suppressor genes are increasingly methylated with age in non-neoplastic gastric epithelia. Cancer Sci 2006; 97: 1155-1158. (Pubitemid 44430640)
    • (2006) Cancer Science , vol.97 , Issue.11 , pp. 1155-1158
    • So, K.1    Tamura, G.2    Honda, T.3    Homma, N.4    Waki, T.5    Togawa, N.6    Nishizuka, S.7    Motoyama, T.8
  • 58
    • 0037537477 scopus 로고    scopus 로고
    • Promoter methylation of E-cadherin gene in gastric mucosa associated with Helicobacter pylori infection and in gastric cancer
    • DOI 10.1136/gut.52.4.502
    • Chan AO, Lam SK, Wong BC, Wong WM, Yuen MF, Yeung YH, Hui WM, Rashid A, Kwong YL: Promoter methylation of E-cadherin gene in gastric mucosa associated with Helicobacter pylori infection and in gastric cancer. Gut 2003; 52: 502-506. (Pubitemid 36363400)
    • (2003) Gut , vol.52 , Issue.4 , pp. 502-506
    • Chan, A.O.-O.1    Lam, S.-K.2    Wong, B.C.-Y.3    Wong, W.-M.4    Yuen, M.-F.5    Yeung, Y.-H.6    Hui, W.-M.7    Rashid, A.8    Kwong, Y.-L.9
  • 60
    • 33745389259 scopus 로고    scopus 로고
    • DNA methylation as a marker for the past and future
    • DOI 10.1007/s00535-006-1846-6
    • Ushijima T, Nakajima T, Maekita T: DNA methylation as a marker for the past and future. J Gastroenterol 2006; 41: 401-407. (Pubitemid 43941905)
    • (2006) Journal of Gastroenterology , vol.41 , Issue.5 , pp. 401-407
    • Ushijima, T.1    Nakajima, T.2    Maekita, T.3
  • 61
    • 38149040758 scopus 로고    scopus 로고
    • CpG island hypermethylation of tumor-suppressor genes in H. pylori - Infected non-neoplastic gastric mucosa is linked with gastric cancer risk
    • Kaise M, Yamasaki T, Yonezawa J, Miwa J, Ohta Y, Tajiri H: CpG island hypermethylation of tumor-suppressor genes in H. pylori - infected non-neoplastic gastric mucosa is linked with gastric cancer risk. Helicobacter 2008; 13: 35-41.
    • (2008) Helicobacter , vol.13 , pp. 35-41
    • Kaise, M.1    Yamasaki, T.2    Yonezawa, J.3    Miwa, J.4    Ohta, Y.5    Tajiri, H.6
  • 64
  • 65
    • 0028956798 scopus 로고
    • Helicobacter pylori eradication in the treatment and differential diagnosis of giant folds in the corpus and fundus of the stomach
    • Stolte M, Bätz CH, Bayerdörffer E, Eidt S: Helicobacter pylori eradication in the treatment and differential diagnosis of giant folds in the corpus and fundus of the stomach. Z Gastroenterol 1995; 33: 198-201.
    • (1995) Z Gastroenterol , vol.33 , pp. 198-201
    • Stolte, M.1    Bätz, C.H.2    Bayerdörffer, E.3    Eidt, S.4
  • 67
    • 0032720948 scopus 로고    scopus 로고
    • Morphological and functional restoration of parietal cells in Helicobacter pylori associated enlarged fold gastritis after eradication
    • Murayama Y, Miyagawa J, Shinomura Y, Kanayama S, Yasunaga Y, Nishibayashi H, Yamamori K, Higashimoto Y, Matsuzawa Y: Morphological and functional restoration of parietal cells in Helicobacter pylori associated enlarged fold gastritis after eradication. Gut 1999; 45: 653-661. (Pubitemid 29492136)
    • (1999) Gut , vol.45 , Issue.5 , pp. 653-661
    • Murayama, Y.1    Miyagawa, J.2    Shinomura, Y.3    Kanayama, S.4    Yasunaga, Y.5    Nishibayashi, H.6    Yamamori, K.7    Higashimoto, Y.8    Matsuzawa, Y.9
  • 70
    • 2342557977 scopus 로고    scopus 로고
    • A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements
    • Yang AS, Estécio MR, Doshi K, Kondo Y, Tajara EH, Issa JP: A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements. Nu cleic Acids Res 2004; 32:e38.
    • (2004) Nu Cleic Acids Res , vol.32
    • Yang, A.S.1    Estécio, M.R.2    Doshi, K.3    Kondo, Y.4    Tajara, E.H.5    Issa, J.P.6
  • 71
    • 0033814412 scopus 로고    scopus 로고
    • Hypomethylation of LINE1 retrotransposon in human hepatocellular carcinomas, but not in surrounding liver cirrhosis
    • Takai D, Yagi Y, Habib N, Sugimura T, Ushijima T: Hypomethylation of LINE1 retrotransposon in human hepatocellular carcinomas, but not in surrounding liver cirrhosis. Jpn J Clin Oncol 2000; 30: 306-309.
    • (2000) Jpn J Clin Oncol , vol.30 , pp. 306-309
    • Takai, D.1    Yagi, Y.2    Habib, N.3    Sugimura, T.4    Ushijima, T.5
  • 74
    • 43049130760 scopus 로고    scopus 로고
    • LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer
    • DOI 10.1002/ijc.23470
    • Ogino S, Kawasaki T, Nosho K, Ohnishi M, Suemoto Y, Kirkner GJ, Fuchs CS: LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer. Int J Cancer 2008; 122: 2767-2773. (Pubitemid 351631379)
    • (2008) International Journal of Cancer , vol.122 , Issue.12 , pp. 2767-2773
    • Ogino, S.1    Kawasaki, T.2    Nosho, K.3    Ohnishi, M.4    Suemoto, Y.5    Kirkner, G.J.6    Fuchs, C.S.7
  • 75
    • 61349143203 scopus 로고    scopus 로고
    • Prognostic implications of and relationship between CpG island hypermethylation and repetitive DNA hypomethylation in hepatocellular carcinoma
    • Lee HS, Kim BH, Cho NY, Yoo EJ, Choi M, Shin SH, Jang JJ, Suh KS, Kim YS, Kang GH: Prognostic implications of and relationship between CpG island hypermethylation and repetitive DNA hypomethylation in hepatocellular carcinoma. Clin Cancer Res 2009; 15: 812-820.
    • (2009) Clin Cancer Res , vol.15 , pp. 812-820
    • Lee, H.S.1    Kim, B.H.2    Cho, N.Y.3    Yoo, E.J.4    Choi, M.5    Shin, S.H.6    Jang, J.J.7    Suh, K.S.8    Kim, Y.S.9    Kang, G.H.10
  • 76
    • 5044220735 scopus 로고    scopus 로고
    • Methylation pattern of CDH13 gene in digestive tract cancers
    • DOI 10.1038/sj.bjc.6602095
    • Hibi K, Kodera Y, Ito K, Akiyama S, Nakao A: Methylation pattern of CDH13 gene in digestive tract cancers. Br J Cancer 2004; 91: 1139-1142. (Pubitemid 39336253)
    • (2004) British Journal of Cancer , vol.91 , Issue.6 , pp. 1139-1142
    • Hibi, K.1    Kodera, Y.2    Ito, K.3    Akiyama, S.4    Nakao, A.5


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