-
1
-
-
7244239389
-
Endothelial NOS is main mediator for shear stress-dependent angiogenesis in skeletal muscle after prazosin administration
-
Baum O, Da Silva-Azevedo L, Willerding G, Wockel A, Planitzer G, Gossrau R, Pries AR, Zakrzewicz A. Endothelial NOS is main mediator for shear stress-dependent angiogenesis in skeletal muscle after prazosin administration. Am J Physiol Heart Circ Physiol 287: H2300-H2308, 2004.
-
(2004)
Am J Physiol Heart Circ Physiol
, vol.287
-
-
Baum, O.1
Da Silva-Azevedo, L.2
Willerding, G.3
Wockel, A.4
Planitzer, G.5
Gossrau, R.6
Pries, A.R.7
Zakrzewicz, A.8
-
2
-
-
0033844886
-
Combretastatin A-4 prodrug: a potent inhibitor of malignant hemangioendothelioma cell proliferation
-
Bohle AS, Leuschner I, Kalthoff H, Henne-Bruns D. Combretastatin A-4 prodrug: a potent inhibitor of malignant hemangioendothelioma cell proliferation. Int J Cancer 87: 838-843, 2000.
-
(2000)
Int J Cancer
, vol.87
, pp. 838-843
-
-
Bohle, A.S.1
Leuschner, I.2
Kalthoff, H.3
Henne-Bruns, D.4
-
3
-
-
0032950870
-
Anti-vascular approaches to solid tumour therapy: evaluation of combretastatin A4 phosphate
-
Chaplin DJ, Pettit GR, Hill SA. Anti-vascular approaches to solid tumour therapy: evaluation of combretastatin A4 phosphate. Anticancer Res 19: 189-195, 1999.
-
(1999)
Anticancer Res
, vol.19
, pp. 189-195
-
-
Chaplin, D.J.1
Pettit, G.R.2
Hill, S.A.3
-
4
-
-
0036401545
-
Vascular endothelial growth factor is expressed in endothelial cells isolated from skeletal muscles of nitric oxide synthase knockout mice during prazosin-induced angiogenesis
-
Da Silva-Azevedo L, Baum O, Zakrzewicz A, Pries AR. Vascular endothelial growth factor is expressed in endothelial cells isolated from skeletal muscles of nitric oxide synthase knockout mice during prazosin-induced angiogenesis. Biochem Biophys Res Commun 297: 1270-1276, 2002.
-
(2002)
Biochem Biophys Res Commun
, vol.297
, pp. 1270-1276
-
-
Da Silva-Azevedo, L.1
Baum, O.2
Zakrzewicz, A.3
Pries, A.R.4
-
5
-
-
0030951899
-
Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature
-
Dark GG, Hill SA, Prise VE, Tozer GM, Pettit GR, Chaplin DJ. Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature. Cancer Res 57: 1829-1834, 1997.
-
(1997)
Cancer Res
, vol.57
, pp. 1829-1834
-
-
Dark, G.G.1
Hill, S.A.2
Prise, V.E.3
Tozer, G.M.4
Pettit, G.R.5
Chaplin, D.J.6
-
6
-
-
0020081554
-
Endothelial cell proliferation as a novel approach to targeting tumour therapy
-
Denekamp J. Endothelial cell proliferation as a novel approach to targeting tumour therapy. Br J Cancer 45: 136-139, 1982.
-
(1982)
Br J Cancer
, vol.45
, pp. 136-139
-
-
Denekamp, J.1
-
7
-
-
59849107870
-
Invited review: activity-induced angiogenesis
-
Egginton S. Invited review: activity-induced angiogenesis. Pflugers Arch 457: 963-977, 2009.
-
(2009)
Pflugers Arch
, vol.457
, pp. 963-977
-
-
Egginton, S.1
-
8
-
-
84860232962
-
Physiological factors influencing capillary growth
-
Egginton S. Physiological factors influencing capillary growth. Acta Physiol 202: 1633-1638, 2011.
-
(2011)
Acta Physiol
, vol.202
, pp. 1633-1638
-
-
Egginton, S.1
-
9
-
-
0027548170
-
Fine structure of capillaries in ischaemic and non ischaemic rat striated muscle. Effect of torbafylline
-
Egginton S, Hudlicka O, Glover M. Fine structure of capillaries in ischaemic and non ischaemic rat striated muscle. Effect of torbafylline. Int J Microcirc Clin Exp 12: 33-44, 1993.
-
(1993)
Int J Microcirc Clin Exp
, vol.12
, pp. 33-44
-
-
Egginton, S.1
Hudlicka, O.2
Glover, M.3
-
10
-
-
0035895762
-
Unorthodox angiogenesis in skeletal muscle
-
Egginton S, Zhou AL, Brown MD, Hudlicka O. Unorthodox angiogenesis in skeletal muscle. Cardiovasc Res 49: 634-646, 2001.
-
(2001)
Cardiovasc Res
, vol.49
, pp. 634-646
-
-
Egginton, S.1
Zhou, A.L.2
Brown, M.D.3
Hudlicka, O.4
-
11
-
-
0028929803
-
Angiogenesis in cancer, vascular, rheumatoid and other disease
-
Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1: 27-31, 1995.
-
(1995)
Nat Med
, vol.1
, pp. 27-31
-
-
Folkman, J.1
-
12
-
-
24644500063
-
Rho, Rac, Pak and angiogenesis: old roles and newly identified responsibilities in endothelial cells
-
Fryer BH, Field J. Rho, Rac, Pak and angiogenesis: old roles and newly identified responsibilities in endothelial cells. Cancer Lett 229: 13-23, 2005.
-
(2005)
Cancer Lett
, vol.229
, pp. 13-23
-
-
Fryer, B.H.1
Field, J.2
-
13
-
-
0031594958
-
The effect of alpha 1 adrenoceptor antagonist prazosin on capillary supply, blood flow and performance in a rat model of chronic muscle ischaemia
-
Fulgenzi G, Graciotti L, Collis MG, Hudlicka O. The effect of alpha 1 adrenoceptor antagonist prazosin on capillary supply, blood flow and performance in a rat model of chronic muscle ischaemia. Eur J Vasc Endovasc Surg 16: 71-77, 1998.
-
(1998)
Eur J Vasc Endovasc Surg
, vol.16
, pp. 71-77
-
-
Fulgenzi, G.1
Graciotti, L.2
Collis, M.G.3
Hudlicka, O.4
-
14
-
-
0035064594
-
Effects of combretastatin A4 phosphate on endothelial cell morphology in vitro and relationship to tumour vascular targeting activity in vivo
-
Galbraith SM, Chaplin DJ, Lee F, Stratford MR, Locke RJ, Vojnovic B, Tozer GM. Effects of combretastatin A4 phosphate on endothelial cell morphology in vitro and relationship to tumour vascular targeting activity in vivo. Anticancer Res 21: 93-102, 2001.
-
(2001)
Anticancer Res
, vol.21
, pp. 93-102
-
-
Galbraith, S.M.1
Chaplin, D.J.2
Lee, F.3
Stratford, M.R.4
Locke, R.J.5
Vojnovic, B.6
Tozer, G.M.7
-
16
-
-
0033679623
-
Matrix metalloproteinase activity is required for activity-induced angiogenesis in rat skeletal muscle
-
Haas TL, Milkiewicz M, Davis SJ, Zhou AL, Egginton S, Brown MD, Madri JA, Hudlicka O. Matrix metalloproteinase activity is required for activity-induced angiogenesis in rat skeletal muscle. Am J Physiol Heart Circ Physiol 279: H1540-H1547, 2000.
-
(2000)
Am J Physiol Heart Circ Physiol
, vol.279
-
-
Haas, T.L.1
Milkiewicz, M.2
Davis, S.J.3
Zhou, A.L.4
Egginton, S.5
Brown, M.D.6
Madri, J.A.7
Hudlicka, O.8
-
17
-
-
0030636277
-
Role of fibrin and plasminogen activators in repair-associated angiogenesis: in vitro studies with human endothelial cells
-
van Hinsbergh VW, Koolwijk P, Hanemaaijer R. Role of fibrin and plasminogen activators in repair-associated angiogenesis: in vitro studies with human endothelial cells. EXS 79: 391-411, 1997.
-
(1997)
EXS
, vol.79
, pp. 391-411
-
-
van Hinsbergh, V.W.1
Koolwijk, P.2
Hanemaaijer, R.3
-
18
-
-
0032729686
-
Antitumor effects due to irreversible stoppage of tumor tissue blood flow: evaluation of a novel combretastatin A-4 derivative, AC7700
-
Hori K, Saito S, Nihei Y, Suzuki M, Sato Y. Antitumor effects due to irreversible stoppage of tumor tissue blood flow: evaluation of a novel combretastatin A-4 derivative, AC7700. Jpn J Cancer Res 90: 1026-1038, 1999.
-
(1999)
Jpn J Cancer Res
, vol.90
, pp. 1026-1038
-
-
Hori, K.1
Saito, S.2
Nihei, Y.3
Suzuki, M.4
Sato, Y.5
-
19
-
-
49249107471
-
Fluid shear attenuates endothelial pseudopodia formation into the capillary lumen
-
Hueck IS, Rossiter K, Artmann GM, Schmid-Schonbein GW. Fluid shear attenuates endothelial pseudopodia formation into the capillary lumen. Microcirculation 15: 531-542, 2008.
-
(2008)
Microcirculation
, vol.15
, pp. 531-542
-
-
Hueck, I.S.1
Rossiter, K.2
Artmann, G.M.3
Schmid-Schonbein, G.W.4
-
20
-
-
41149138113
-
Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer
-
Jain RK. Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer. Nat Rev Cancer 8: 309-316, 2008.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 309-316
-
-
Jain, R.K.1
-
21
-
-
0037085753
-
The tumor vascular targeting agent combretastatin A-4-phosphate induces reorganization of the actin cytoskeleton and early membrane blebbing in human endothelial cells
-
Kanthou C, Tozer GM. The tumor vascular targeting agent combretastatin A-4-phosphate induces reorganization of the actin cytoskeleton and early membrane blebbing in human endothelial cells. Blood 99: 2060-2069, 2002.
-
(2002)
Blood
, vol.99
, pp. 2060-2069
-
-
Kanthou, C.1
Tozer, G.M.2
-
22
-
-
5044220051
-
Cyclic mechanical strain inhibits skeletal myogenesis through activation of focal adhesion kinase, Rac-1 GTPase, and NF-kappaB transcription factor
-
Kumar A, Murphy R, Robinson P, Wei L, Boriek AM. Cyclic mechanical strain inhibits skeletal myogenesis through activation of focal adhesion kinase, Rac-1 GTPase, and NF-kappaB transcription factor. FASEB J 18: 1524-1535, 2004.
-
(2004)
FASEB J
, vol.18
, pp. 1524-1535
-
-
Kumar, A.1
Murphy, R.2
Robinson, P.3
Wei, L.4
Boriek, A.M.5
-
23
-
-
77950976702
-
Disrupting established tumor blood vessels: an emerging therapeutic strategy for cancer
-
McKeage MJ, Baguley BC. Disrupting established tumor blood vessels: an emerging therapeutic strategy for cancer. Cancer 116: 1859-1871, 2010.
-
(2010)
Cancer
, vol.116
, pp. 1859-1871
-
-
McKeage, M.J.1
Baguley, B.C.2
-
24
-
-
79952455505
-
The VEGF/Rho GTPase signalling pathway: a promising target for anti-angiogenic/anti-invasion therapy
-
van der Meel R, Symons MH, Kudernatsch R, Kok RJ, Schiffelers RM, Storm G, Gallagher WM, Byrne AT. The VEGF/Rho GTPase signalling pathway: a promising target for anti-angiogenic/anti-invasion therapy. Drug Discov Today 16: 219-228, 2011.
-
(2011)
Drug Discov Today
, vol.16
, pp. 219-228
-
-
van der Meel, R.1
Symons, M.H.2
Kudernatsch, R.3
Kok, R.J.4
Schiffelers, R.M.5
Storm, G.6
Gallagher, W.M.7
Byrne, A.T.8
-
25
-
-
0037324359
-
Involvement of RhoA/Rho kinase signaling in VEGF-induced endothelial cell migration and angiogenesis in vitro
-
van Nieuw Amerongen GP, Koolwijk P, Versteilen A, van Hinsbergh VW. Involvement of RhoA/Rho kinase signaling in VEGF-induced endothelial cell migration and angiogenesis in vitro. Arterioscler Thromb Vasc Biol 23: 211-217, 2003.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 211-217
-
-
van Nieuw Amerongen, G.P.1
Koolwijk, P.2
Versteilen, A.3
van Hinsbergh, V.W.4
-
26
-
-
0033817283
-
Determinants of anti-vascular action by combretastatin A-4 phosphate: role of nitric oxide
-
Parkins CS, Holder AL, Hill SA, Chaplin DJ, Tozer GM. Determinants of anti-vascular action by combretastatin A-4 phosphate: role of nitric oxide. Br J Cancer 83: 811-816, 2000.
-
(2000)
Br J Cancer
, vol.83
, pp. 811-816
-
-
Parkins, C.S.1
Holder, A.L.2
Hill, S.A.3
Chaplin, D.J.4
Tozer, G.M.5
-
27
-
-
0023065565
-
Isolation, structure, and synthesis of combretastatins A-1 and B-1, potent new inhibitors of microtubule assembly, derived from Combretum caffrum
-
Pettit GR, Singh SB, Niven ML, Hamel E, Schmidt JM. Isolation, structure, and synthesis of combretastatins A-1 and B-1, potent new inhibitors of microtubule assembly, derived from Combretum caffrum. J Nat Prod 50: 119-131, 1987.
-
(1987)
J Nat Prod
, vol.50
, pp. 119-131
-
-
Pettit, G.R.1
Singh, S.B.2
Niven, M.L.3
Hamel, E.4
Schmidt, J.M.5
-
28
-
-
0029044610
-
Antineoplastic agents 322. synthesis of combretastatin A-4 prodrugs
-
Pettit GR, Temple C Jr., Narayanan VL, Varma R, Simpson MJ, Boyd MR, Rener GA, Bansal N. Antineoplastic agents 322. synthesis of combretastatin A-4 prodrugs. Anticancer Drug Des 10: 299-309, 1995.
-
(1995)
Anticancer Drug Des
, vol.10
, pp. 299-309
-
-
Pettit, G.R.1
Temple Jr., C.2
Narayanan, V.L.3
Varma, R.4
Simpson, M.J.5
Boyd, M.R.6
Rener, G.A.7
Bansal, N.8
-
29
-
-
0038387873
-
Conserved microtubule-actin interactions in cell movement and morphogenesis
-
Rodriguez OC, Schaefer AW, Mandato CA, Forscher P, Bement WM, Waterman-Storer CM. Conserved microtubule-actin interactions in cell movement and morphogenesis. Nat Cell Biol 5: 599-609, 2003.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 599-609
-
-
Rodriguez, O.C.1
Schaefer, A.W.2
Mandato, C.A.3
Forscher, P.4
Bement, W.M.5
Waterman-Storer, C.M.6
-
30
-
-
0042386700
-
Phase I clinical trial of weekly combretastatin A4 phosphate: clinical and pharmacokinetic results
-
Rustin GJ, Galbraith SM, Anderson H, Stratford M, Folkes LK, Sena L, Gumbrell L, Price PM. Phase I clinical trial of weekly combretastatin A4 phosphate: clinical and pharmacokinetic results. J Clin Oncol 21: 2815-2822, 2003.
-
(2003)
J Clin Oncol
, vol.21
, pp. 2815-2822
-
-
Rustin, G.J.1
Galbraith, S.M.2
Anderson, H.3
Stratford, M.4
Folkes, L.K.5
Sena, L.6
Gumbrell, L.7
Price, P.M.8
-
31
-
-
65249123159
-
Anti-vascular actions of microtubule-binding drugs
-
Schwartz EL. Anti-vascular actions of microtubule-binding drugs. Clin Cancer Res 15: 2594-2601, 2009.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2594-2601
-
-
Schwartz, E.L.1
-
32
-
-
65549090459
-
A review and update of the current status of the vasculature-disabling agent combretastatin-A4 phosphate (CA4P)
-
Siemann DW, Chaplin DJ, Walicke PA. A review and update of the current status of the vasculature-disabling agent combretastatin-A4 phosphate (CA4P). Expert Opin Investig Drugs 18: 189-197, 2009.
-
(2009)
Expert Opin Investig Drugs
, vol.18
, pp. 189-197
-
-
Siemann, D.W.1
Chaplin, D.J.2
Walicke, P.A.3
-
33
-
-
0035417875
-
Mechanisms associated with tumor vascular shut-down induced by combretastatin A-4 phosphate: intravital microscopy and measurement of vascular permeability
-
Tozer GM, Prise VE, Wilson J, Cemazar M, Shan S, Dewhirst MW, Barber PR, Vojnovic B, Chaplin DJ. Mechanisms associated with tumor vascular shut-down induced by combretastatin A-4 phosphate: intravital microscopy and measurement of vascular permeability. Cancer Res 61: 6413-6422, 2001.
-
(2001)
Cancer Res
, vol.61
, pp. 6413-6422
-
-
Tozer, G.M.1
Prise, V.E.2
Wilson, J.3
Cemazar, M.4
Shan, S.5
Dewhirst, M.W.6
Barber, P.R.7
Vojnovic, B.8
Chaplin, D.J.9
-
34
-
-
0033119771
-
Combretastatin A-4 phosphate as a tumor vascular-targeting agent: early effects in tumors and normal tissues
-
Tozer GM, Prise VE, Wilson J, Locke RJ, Vojnovic B, Stratford MR, Dennis MF, Chaplin DJ. Combretastatin A-4 phosphate as a tumor vascular-targeting agent: early effects in tumors and normal tissues. Cancer Res 59: 1626-1634, 1999.
-
(1999)
Cancer Res
, vol.59
, pp. 1626-1634
-
-
Tozer, G.M.1
Prise, V.E.2
Wilson, J.3
Locke, R.J.4
Vojnovic, B.5
Stratford, M.R.6
Dennis, M.F.7
Chaplin, D.J.8
-
35
-
-
27644466314
-
Combretastatin A4 phosphate induces rapid regression of tumor neovessels and growth through interference with vascular endothelial-cadherin signaling
-
Vincent L, Kermani P, Young LM, Cheng J, Zhang F, Shido K, Lam G, Bompais-Vincent H, Zhu Z, Hicklin DJ, Bohlen P, Chaplin DJ, May C, Rafii S. Combretastatin A4 phosphate induces rapid regression of tumor neovessels and growth through interference with vascular endothelial-cadherin signaling. J Clin Invest 115: 2992-3006, 2005.
-
(2005)
J Clin Invest
, vol.115
, pp. 2992-3006
-
-
Vincent, L.1
Kermani, P.2
Young, L.M.3
Cheng, J.4
Zhang, F.5
Shido, K.6
Lam, G.7
Bompais-Vincent, H.8
Zhu, Z.9
Hicklin, D.J.10
Bohlen, P.11
Chaplin, D.J.12
May, C.13
Rafii, S.14
-
36
-
-
33645853180
-
A differential role for nitric oxide in two forms of physiological angiogenesis in mouse
-
Williams JL, Cartland D, Hussain A, Egginton S. A differential role for nitric oxide in two forms of physiological angiogenesis in mouse. J Physiol 570: 445-454, 2006.
-
(2006)
J Physiol
, vol.570
, pp. 445-454
-
-
Williams, J.L.1
Cartland, D.2
Hussain, A.3
Egginton, S.4
-
37
-
-
0031655427
-
Capillary growth in overloaded, hypertrophic adult rat skeletal muscle: an ultrastructural study
-
Zhou AL, Egginton S, Brown MD, Hudlicka O. Capillary growth in overloaded, hypertrophic adult rat skeletal muscle: an ultrastructural study. Anat Rec 252: 49-63, 1998.
-
(1998)
Anat Rec
, vol.252
, pp. 49-63
-
-
Zhou, A.L.1
Egginton, S.2
Brown, M.D.3
Hudlicka, O.4
-
38
-
-
0031874862
-
Internal division of capillaries in rat skeletal muscle in response to chronic vasodilator treatment with alpha1-antagonist prazosin
-
Zhou A, Egginton S, Hudlicka O, Brown MD. Internal division of capillaries in rat skeletal muscle in response to chronic vasodilator treatment with alpha1-antagonist prazosin. Cell Tissue Res 293: 293-303, 1998.
-
(1998)
Cell Tissue Res
, vol.293
, pp. 293-303
-
-
Zhou, A.1
Egginton, S.2
Hudlicka, O.3
Brown, M.D.4
|