An intravenous exposure mouse model for prediction of potential drug-sensitization using reporter antigens popliteal lymph node assay

Journal of Applied Toxicology

Volumn 32, Issue 6, 2012, Pages 395-401

  Lin, Mingbao ^a   Sun, Wei ^b   Wang, Yingchao ^a   Li, Xiang ^a   Jin, Yecheng ^a   Gong, Wan ^a   Fan, Xiaohui ^a   Wang, Yi ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Immune mediated drug hypersensitivity reaction; Intravenous; Mouse model; Popliteal lymph node assay; Reporter antigen

Indexed keywords

CONCANAVALIN A; DICLOFENAC; GAMMA INTERFERON; IMMUNOGLOBULIN G1; INTERLEUKIN 4; OVALBUMIN; TRINITROPHENYL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCING CELL; ARTICLE; CD4+ T LYMPHOCYTE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG HYPERSENSITIVITY; FEMALE; IMMUNE RESPONSE; IMMUNOASSAY; MOUSE; NONHUMAN; POPLITEAL LYMPH NODE ASSAY; PREDICTION; PRIORITY JOURNAL; TH1 CELL; TH2 CELL;

ADJUVANTS, IMMUNOLOGIC; ALLERGENS; ANIMALS; ANTIGEN-ANTIBODY REACTIONS; ANTIGENS; CELL PROLIFERATION; CONCANAVALIN A; DICLOFENAC; DRUG HYPERSENSITIVITY; FEMALE; INJECTIONS, INTRAVENOUS; LOCAL LYMPH NODE ASSAY; LYMPH NODES; MICE; MICE, INBRED BALB C; OVALBUMIN; RISK ASSESSMENT; TRINITROBENZENES;

MUS;

EID: 84860248863     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.1696     Document Type: Article

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