메뉴 건너뛰기




Volumn 29, Issue 3, 2009, Pages 233-241

Cytokine profiling of chemical allergens in mice: Impact of mitogen on selectivity of response

Author keywords

2,4 dinitrochlorobenzene; Chemical allergens; Cytokines; Mitogen; Trimellitic anhydride

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; MITOGENIC AGENT; TRIMELLITIC ANHYDRIDE;

EID: 64549157633     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.1401     Document Type: Article
Times cited : (8)

References (50)
  • 1
    • 33845286199 scopus 로고    scopus 로고
    • Animal models to test respiratory allergy of low molecular weight chemicals: A guidance
    • DOI: 10.1016/j.ymeth.2006.07.005
    • Arts JH, Kuper CF. 2007. Animal models to test respiratory allergy of low molecular weight chemicals: a guidance. Methods 41: 61-71. DOI: 10.1016/j.ymeth.2006.07.005
    • (2007) Methods , vol.41 , pp. 61-71
    • Arts, J.H.1    Kuper, C.F.2
  • 2
    • 28844463398 scopus 로고    scopus 로고
    • TDI can induce respiratory allergy with Th2-dominated response in mice
    • DOI: 10.1016/j.tox.2005.09.013
    • Ban M, Morel G, Langonne I, Huguet N, Pepin E, Binet S. 2006. TDI can induce respiratory allergy with Th2-dominated response in mice. Toxicology 218: 39-47. DOI: 10.1016/j.tox.2005.09.013
    • (2006) Toxicology , vol.218 , pp. 39-47
    • Ban, M.1    Morel, G.2    Langonne, I.3    Huguet, N.4    Pepin, E.5    Binet, S.6
  • 4
    • 0037114422 scopus 로고    scopus 로고
    • Temporal changes in cytokine gene expression profiles induced in mice by trimellitic anhydride
    • DOI: 10.1016/S0378-4272(02)00299-8
    • Betts CJ, Dearman RJ, Flanagan BF, Kimber I. 2002. Temporal changes in cytokine gene expression profiles induced in mice by trimellitic anhydride. Toxicol. Lett. 136: 121-132. DOI: 10.1016/S0378-4272(02)00299-8
    • (2002) Toxicol. Lett , vol.136 , pp. 121-132
    • Betts, C.J.1    Dearman, R.J.2    Flanagan, B.F.3    Kimber, I.4
  • 5
    • 4043075557 scopus 로고    scopus 로고
    • Intradermal exposure of BALB/c strain mice to peanut protein elicits a type 2 cytokine response
    • DOI: 10.1016/j.fct.2004.05.004
    • Betts CJ, Flanagan BF, Caddick HT, Dearman RJ, Kimber I. 2004. Intradermal exposure of BALB/c strain mice to peanut protein elicits a type 2 cytokine response. Food Chem. Toxicol. 42: 1589-1599. DOI: 10.1016/j.fct.2004.05.004
    • (2004) Food Chem. Toxicol , vol.42 , pp. 1589-1599
    • Betts, C.J.1    Flanagan, B.F.2    Caddick, H.T.3    Dearman, R.J.4    Kimber, I.5
  • 7
    • 0035073918 scopus 로고    scopus 로고
    • Cytokine fingerprinting and hazard assessment of chemical respiratory allergy
    • DOI: 10.1002/jat743
    • Dearman RJ, Kimber I. 2001. Cytokine fingerprinting and hazard assessment of chemical respiratory allergy. J. Appl. Toxicol. 21 : 153163. DOI: 10.1002/jat743
    • (2001) J. Appl. Toxicol , vol.21 , pp. 153163
    • Dearman, R.J.1    Kimber, I.2
  • 8
    • 84940627661 scopus 로고
    • Inhalation exposure of mice to trimellitic anhydride induces both IgG and IgE anti-hapten antibody
    • Dearman RJ, Hegarty JM, Kimber I. 1991. Inhalation exposure of mice to trimellitic anhydride induces both IgG and IgE anti-hapten antibody. Int. Arch. Allergy Appl. Immunol. 95: 70-76.
    • (1991) Int. Arch. Allergy Appl. Immunol , vol.95 , pp. 70-76
    • Dearman, R.J.1    Hegarty, J.M.2    Kimber, I.3
  • 9
    • 0036708569 scopus 로고    scopus 로고
    • Interleukins 5 and 13 characterize immune responses to respiratory sensitizing acid anhydrides
    • DOI: 10.1002/jat.865
    • Dearman RJ, Filby A, Humphreys IR, Kimber I. 2002a. Interleukins 5 and 13 characterize immune responses to respiratory sensitizing acid anhydrides. J. Appl. Toxicol. 22: 317-325. DOI: 10.1002/jat.865
    • (2002) J. Appl. Toxicol , vol.22 , pp. 317-325
    • Dearman, R.J.1    Filby, A.2    Humphreys, I.R.3    Kimber, I.4
  • 10
    • 0036888288 scopus 로고    scopus 로고
    • Cytokine fingerprinting of chemical allergens: Species comparisons and statistical analyses
    • DOI: 10.1016/S0278- 6915(02)00179-5
    • Dearman RJ, Warbrick EV, Skinner R, Kimber I. 2002b. Cytokine fingerprinting of chemical allergens: species comparisons and statistical analyses. Food Chem. Toxicol. 40: 107-118. DOI: 10.1016/S0278- 6915(02)00179-5
    • (2002) Food Chem. Toxicol , vol.40 , pp. 107-118
    • Dearman, R.J.1    Warbrick, E.V.2    Skinner, R.3    Kimber, I.4
  • 12
    • 17744397362 scopus 로고    scopus 로고
    • Allergen-induced cytokine phenotypes in mice: Role of CD4 and CD8 T cell populations
    • DOI: 10.111365-2222.2005.02209.X
    • Dearman RJ, Humphreys N, Skinner RA, Kimber I. 2005. Allergen-induced cytokine phenotypes in mice: role of CD4 and CD8 T cell populations. Clin. Exp. Allergy 35: 498-505. DOI: 10.111365-2222.2005.02209.X
    • (2005) Clin. Exp. Allergy , vol.35 , pp. 498-505
    • Dearman, R.J.1    Humphreys, N.2    Skinner, R.A.3    Kimber, I.4
  • 13
    • 53249093699 scopus 로고    scopus 로고
    • Cytokine profiling of chemical allergens in mice: Measurement of message versus protein
    • Dearman RJ, Betts CJ, Caddick HT, Flanagan BF, Kimber I. 2008. Cytokine profiling of chemical allergens in mice: measurement of message versus protein. Toxicology 252: 17-25.
    • (2008) Toxicology , vol.252 , pp. 17-25
    • Dearman, R.J.1    Betts, C.J.2    Caddick, H.T.3    Flanagan, B.F.4    Kimber, I.5
  • 14
    • 0027197709 scopus 로고
    • Allergen exposure induces the activation of allergen-specific Th2 cells in the airway mucosa of patients with allergic respiratory disorders
    • Del Prete GF, De Carli M, D'Elios MM, Maestrelli P, Ricci M, Fabbri L, Romagnani S. 1993. Allergen exposure induces the activation of allergen-specific Th2 cells in the airway mucosa of patients with allergic respiratory disorders. Eur. J. Immunol. 23: 1445-1449.
    • (1993) Eur. J. Immunol , vol.23 , pp. 1445-1449
    • Del Prete, G.F.1    De Carli, M.2    D'Elios, M.M.3    Maestrelli, P.4    Ricci, M.5    Fabbri, L.6    Romagnani, S.7
  • 15
    • 0030587789 scopus 로고    scopus 로고
    • Naive and effector CD4 T cells differ in their requirements for T cell receptor versus costimulatory signals
    • Dubey C, Croft M, Swain SL. 1996. Naive and effector CD4 T cells differ in their requirements for T cell receptor versus costimulatory signals. J. Immunol. 157: 3280-3289.
    • (1996) J. Immunol , vol.157 , pp. 3280-3289
    • Dubey, C.1    Croft, M.2    Swain, S.L.3
  • 16
    • 2942711806 scopus 로고    scopus 로고
    • Allergic rhinitis induced by intranasal sensitization and challenge with trimellitic anhydride but not with dinitrochlorobenzene or oxazolone in A/J mice
    • DOI: 10.1093/toxsci/kfh112
    • Farraj AK, Harkema JR, Kaminski NE. 2004. Allergic rhinitis induced by intranasal sensitization and challenge with trimellitic anhydride but not with dinitrochlorobenzene or oxazolone in A/J mice. Toxicol. Sci. 79: 315-325. DOI: 10.1093/toxsci/kfh112
    • (2004) Toxicol. Sci , vol.79 , pp. 315-325
    • Farraj, A.K.1    Harkema, J.R.2    Kaminski, N.E.3
  • 17
    • 33745593443 scopus 로고    scopus 로고
    • Topical application versus intranasal instillation: A qualitative comparison of the effect of route of sensitization on trimellitic anhydride-induced allergic rhinitis in A/J mice
    • DOI: 10.1093/toxsci/kfj191
    • Farraj AK, Harkema JR, Kaminski NE. 2006. Topical application versus intranasal instillation: a qualitative comparison of the effect of route of sensitization on trimellitic anhydride-induced allergic rhinitis in A/J mice. Toxicol. Sci. 92: 321-328. DOI: 10.1093/toxsci/kfj191
    • (2006) Toxicol. Sci , vol.92 , pp. 321-328
    • Farraj, A.K.1    Harkema, J.R.2    Kaminski, N.E.3
  • 18
    • 0030219762 scopus 로고    scopus 로고
    • The immunology of respiratory allergies
    • Frew AJ. 1996. The immunology of respiratory allergies. Toxicol. Lett. 86: 65-72.
    • (1996) Toxicol. Lett , vol.86 , pp. 65-72
    • Frew, A.J.1
  • 19
    • 0035070195 scopus 로고    scopus 로고
    • Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets
    • DOI: 10.1016/51074-7613(01) 00103-0
    • Grogan JL, Mohrs M, Harman B, Lacy DA, Sedat JW, Locksley RM. 2001. Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets. Immunity 14: 205-215. DOI: 10.1016/51074-7613(01) 00103-0
    • (2001) Immunity , vol.14 , pp. 205-215
    • Grogan, J.L.1    Mohrs, M.2    Harman, B.3    Lacy, D.A.4    Sedat, J.W.5    Locksley, R.M.6
  • 20
    • 0035891551 scopus 로고    scopus 로고
    • Assessment of preferential Th1 or Th2 induction by low-molecular-weight compounds using a reverse transcription-polymerase chain reaction method: Comparison of two mouse strains, C57BL/6 and BALB/c
    • DOI: 10.1006/taap.2001.9286
    • Hayashi M, Higashi K, Kato H, Kaneko H. 2001. Assessment of preferential Th1 or Th2 induction by low-molecular-weight compounds using a reverse transcription-polymerase chain reaction method: comparison of two mouse strains, C57BL/6 and BALB/c. Toxicol. Appl. Pharmacol. 177: 38-45. DOI: 10.1006/taap.2001.9286
    • (2001) Toxicol. Appl. Pharmacol , vol.177 , pp. 38-45
    • Hayashi, M.1    Higashi, K.2    Kato, H.3    Kaneko, H.4
  • 22
    • 42049117573 scopus 로고    scopus 로고
    • Chemical respiratory allergy and occupational asthma: What are the key areas of uncertainty?
    • DOI: 10.1002/jat.1336
    • Isola D, Kimber I, Sarlo K, Lalko J, Stipes IG. 2008. Chemical respiratory allergy and occupational asthma: what are the key areas of uncertainty? J. Appl. Toxicol. 28: 249-253. DOI: 10.1002/jat.1336
    • (2008) J. Appl. Toxicol , vol.28 , pp. 249-253
    • Isola, D.1    Kimber, I.2    Sarlo, K.3    Lalko, J.4    Stipes, I.G.5
  • 24
    • 0025815575 scopus 로고
    • Comparison of clinical and experimental data from an animal model of pulmonary immunologic sensitivity
    • Karol M. 1991. Comparison of clinical and experimental data from an animal model of pulmonary immunologic sensitivity. Ann. Allergy 66: 485-489.
    • (1991) Ann. Allergy , vol.66 , pp. 485-489
    • Karol, M.1
  • 25
    • 30744466671 scopus 로고    scopus 로고
    • The role of T lymphocytes in asthma
    • DOI: 10.1159/000090230
    • Kay AB. 2006. The role of T lymphocytes in asthma. Chem. Immunol. Allergy 91: 59-75. DOI: 10.1159/000090230
    • (2006) Chem. Immunol. Allergy , vol.91 , pp. 59-75
    • Kay, A.B.1
  • 26
    • 33644928728 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate protects toluene diisocyanate-induced airway inflammation in a murine model of asthma
    • DOI: 10.1016/j.febslet.2006.02.052
    • Kim SH, Park HJ, Lee CM, Chol IW, Moon DO, Roh HJ, Lee HK, Park YM. 2006. Epigallocatechin-3-gallate protects toluene diisocyanate-induced airway inflammation in a murine model of asthma. FEBS Lett. 580: 1883-1890. DOI: 10.1016/j.febslet.2006.02.052
    • (2006) FEBS Lett , vol.580 , pp. 1883-1890
    • Kim, S.H.1    Park, H.J.2    Lee, C.M.3    Chol, I.W.4    Moon, D.O.5    Roh, H.J.6    Lee, H.K.7    Park, Y.M.8
  • 27
    • 0031154749 scopus 로고    scopus 로고
    • Cell and molecular biology of chemical allergy
    • Kimber I, Dearman RJ. 1997. Cell and molecular biology of chemical allergy. Clin. Rev. Allergy Immunol. 15: 145-168.
    • (1997) Clin. Rev. Allergy Immunol , vol.15 , pp. 145-168
    • Kimber, I.1    Dearman, R.J.2
  • 28
    • 0037184811 scopus 로고    scopus 로고
    • Chemical respiratory allergy: Role of IgE antibody and relevance of route of exposure
    • DOI: 10.1016/S0300-483X(02)00299-8
    • Kimber I, Dearman RJ. 2002. Chemical respiratory allergy: role of IgE antibody and relevance of route of exposure. Toxicology 181-182: 311-315. DOI: 10.1016/S0300-483X(02)00299-8
    • (2002) Toxicology , vol.181-182 , pp. 311-315
    • Kimber, I.1    Dearman, R.J.2
  • 29
    • 20444364564 scopus 로고    scopus 로고
    • Airway inflammation and immunological events in a rat model exposed to toluene diisocyanate
    • DOI: 10.1016/j.fct2005.03.05
    • Kouadio K, Zheng KC, Tuekpe MKN, Todokiri H, Ariizumi M. 2005. Airway inflammation and immunological events in a rat model exposed to toluene diisocyanate. Food Chem. Toxicol. 43: 1281-1288. DOI: 10.1016/j.fct2005.03.05
    • (2005) Food Chem. Toxicol , vol.43 , pp. 1281-1288
    • Kouadio, K.1    Zheng, K.C.2    Tuekpe, M.K.N.3    Todokiri, H.4    Ariizumi, M.5
  • 30
    • 0038744380 scopus 로고    scopus 로고
    • Kinetics and STAT4- or STAT6-mediated regulation of genes involved in lymphocyte polarization to Th1 and Th2 cells
    • DOI: 10.1002/eji.200323899
    • Lund RJ, Ylikoski EK, Aittokallio T, Nevalainen O, Lahesmaa R. 2003. Kinetics and STAT4- or STAT6-mediated regulation of genes involved in lymphocyte polarization to Th1 and Th2 cells. Eur. J. Immunol. 33: 1105-1116. DOI: 10.1002/eji.200323899
    • (2003) Eur. J. Immunol , vol.33 , pp. 1105-1116
    • Lund, R.J.1    Ylikoski, E.K.2    Aittokallio, T.3    Nevalainen, O.4    Lahesmaa, R.5
  • 32
    • 0035869314 scopus 로고    scopus 로고
    • The determination of draining lymph node cell cytokine mRNA levels in BALB/c mice following dermal sodium lauryl sulfate, dinitrofluorobenzene, and toluene diisocyanate exposure
    • DOI: 10.1006/taap.2000.9123
    • Manetz TC, Pettit DA, Meade BJ. 2001. The determination of draining lymph node cell cytokine mRNA levels in BALB/c mice following dermal sodium lauryl sulfate, dinitrofluorobenzene, and toluene diisocyanate exposure. Toxicol. Appl. Pharm. 171: 174-183. DOI: 10.1006/taap.2000.9123
    • (2001) Toxicol. Appl. Pharm , vol.171 , pp. 174-183
    • Manetz, T.C.1    Pettit, D.A.2    Meade, B.J.3
  • 34
    • 0034830261 scopus 로고    scopus 로고
    • Importance of inflammatory and immune components in a mouse model of airway reactivity to toluene diisocyanate
    • DOI: 10.1165/rcmb.4614
    • Matheson JM, Lange RW, Lemus R, Karol MH, Luster MI. 2001. Importance of inflammatory and immune components in a mouse model of airway reactivity to toluene diisocyanate. Clin. Exp. Allergy 31: 1067-1076. DOI: 10.1165/rcmb.4614
    • (2001) Clin. Exp. Allergy , vol.31 , pp. 1067-1076
    • Matheson, J.M.1    Lange, R.W.2    Lemus, R.3    Karol, M.H.4    Luster, M.I.5
  • 35
    • 0031804074 scopus 로고    scopus 로고
    • + T cells in mice following primary exposure to chemical allergens: Evidence for functional differentiation of T lymphocytes
    • DOI: 10.1159/000023934
    • + T cells in mice following primary exposure to chemical allergens: evidence for functional differentiation of T lymphocytes. Int. Arch. Allergy Immunol. 116: 116-123. DOI: 10.1159/000023934
    • (1998) Int. Arch. Allergy Immunol , vol.116 , pp. 116-123
    • Moussavi, A.1    Dearman, R.J.2    Kimber, I.3    Kemeny, D.M.4
  • 36
    • 0027514718 scopus 로고
    • Exposure to methylene diphenyl diisocyanate in coal mines
    • Nemery B, Lenaerts L. 1993. Exposure to methylene diphenyl diisocyanate in coal mines. Lancet 341: 318.
    • (1993) Lancet , vol.341 , pp. 318
    • Nemery, B.1    Lenaerts, L.2
  • 37
    • 0242578407 scopus 로고    scopus 로고
    • Respiratory hypersensitivity to trimellitic anhydride in Brown Norway rats: Analysis of dose-response following topical induction and time course following repeated inhalation challenge
    • DOI: 10.1010/S0300-483X(03)00285-3
    • Pauluhn J. 2003. Respiratory hypersensitivity to trimellitic anhydride in Brown Norway rats: analysis of dose-response following topical induction and time course following repeated inhalation challenge. Toxicology 194: 1-17. DOI: 10.1010/S0300-483X(03)00285-3
    • (2003) Toxicology , vol.194 , pp. 1-17
    • Pauluhn, J.1
  • 38
    • 37349032531 scopus 로고    scopus 로고
    • Brown Norway rat asthma model of diphenylmethane- 4,4'-diisocyanate (MDI): Impact of vehicle for topical induction
    • DOI: 10.1016/j.ytph.2007.09.003
    • Pauluhn J. 2008. Brown Norway rat asthma model of diphenylmethane- 4,4'-diisocyanate (MDI): impact of vehicle for topical induction. Regul. Toxicol. Pharmacol. 50: 144-154. DOI: 10.1016/j.ytph.2007.09.003
    • (2008) Regul. Toxicol. Pharmacol , vol.50 , pp. 144-154
    • Pauluhn, J.1
  • 40
    • 12344260785 scopus 로고    scopus 로고
    • Cytokine mRNA profiles for isocyanates with known and unknown potential to induce respiratory sensitization
    • DOI: 10.1016/j.tox.2004.11.001
    • Plitnick LM, Loveless SL, Ladics GS, Holsapple MP, Selgrade MJ, Sailstad DM, Smialowicz RJ. 2005. Cytokine mRNA profiles for isocyanates with known and unknown potential to induce respiratory sensitization. Toxicology 207: 487-499. DOI: 10.1016/j.tox.2004.11.001
    • (2005) Toxicology , vol.207 , pp. 487-499
    • Plitnick, L.M.1    Loveless, S.L.2    Ladics, G.S.3    Holsapple, M.P.4    Selgrade, M.J.5    Sailstad, D.M.6    Smialowicz, R.J.7
  • 41
    • 0028348113 scopus 로고
    • Induction of respiratory hypersensitivity to diphenylmethane-4,4'-diisocyanate (MDI) in guinea pigs. Influence of route of exposure
    • Rattray NJ, Botham PA, Hext PM, Woodcock DR, Fielding I, Dearman RJ, Kimber I. 1994. Induction of respiratory hypersensitivity to diphenylmethane-4,4'-diisocyanate (MDI) in guinea pigs. Influence of route of exposure. Toxicology 88: 15-30.
    • (1994) Toxicology , vol.88 , pp. 15-30
    • Rattray, N.J.1    Botham, P.A.2    Hext, P.M.3    Woodcock, D.R.4    Fielding, I.5    Dearman, R.J.6    Kimber, I.7
  • 42
    • 0032536172 scopus 로고    scopus 로고
    • Inducible interleukin 4 (IL-4) production and mRNA expression following exposure of mice to chemical allergens
    • Ryan CA, Dearman RJ, Kimber I, Gerberick GF. 1998. Inducible interleukin 4 (IL-4) production and mRNA expression following exposure of mice to chemical allergens. Toxicol. Lett. 94: 1-11.
    • (1998) Toxicol. Lett , vol.94 , pp. 1-11
    • Ryan, C.A.1    Dearman, R.J.2    Kimber, I.3    Gerberick, G.F.4
  • 44
  • 45
    • 0034761322 scopus 로고    scopus 로고
    • Cytokine expression profiles during murine contact allergy: T helper 2 cytokines are expressed irrespective of the type of contact allergen
    • DOI: 10.1007/s002040100267
    • Ulrich P, Grenet O, Bluemel J, Vohr HV, Weimann C, Grundler O, Suter W. 2001. Cytokine expression profiles during murine contact allergy: T helper 2 cytokines are expressed irrespective of the type of contact allergen. Arch. Toxicol. 75: 470-479. DOI: 10.1007/s002040100267
    • (2001) Arch. Toxicol , vol.75 , pp. 470-479
    • Ulrich, P.1    Grenet, O.2    Bluemel, J.3    Vohr, H.V.4    Weimann, C.5    Grundler, O.6    Suter, W.7
  • 46
    • 0034650371 scopus 로고    scopus 로고
    • Assessment of preferential T-helper 1 or T-helper 2 induction by low molecular weight compounds using the local lymph node assay in conjunction with RT-PCR and ELISA for interferon-σ and interleukin-4
    • DOI:10.1006/taap.1999.8841
    • Vandebriel RJ, De Jong WH, Spiekstra SW, Van Djik M, Fluitman A, Garssen J, Van Loveren H. 2000. Assessment of preferential T-helper 1 or T-helper 2 induction by low molecular weight compounds using the local lymph node assay in conjunction with RT-PCR and ELISA for interferon-σ and interleukin-4. Toxicol. Appl. Pharmacol. 162: 77-85. DOI:10.1006/taap.1999.8841
    • (2000) Toxicol. Appl. Pharmacol , vol.162 , pp. 77-85
    • Vandebriel, R.J.1    De Jong, W.H.2    Spiekstra, S.W.3    Van Djik, M.4    Fluitman, A.5    Garssen, J.6    Van Loveren, H.7
  • 47
    • 0037718337 scopus 로고    scopus 로고
    • Impact of exposure duration by low molecular weight compounds on interferon- gamma and interleukin-4 mRNA expression and production in the draining lymph nodes of mice
    • DOI: 10.1016/ S0300-483X(02)00742-4
    • Vandebriel RJ, De Jong WH, Hendriks JJA, Van Loveren H. 2003. Impact of exposure duration by low molecular weight compounds on interferon- gamma and interleukin-4 mRNA expression and production in the draining lymph nodes of mice. Toxicology 188: 1-13. DOI: 10.1016/ S0300-483X(02)00742-4
    • (2003) Toxicology , vol.188 , pp. 1-13
    • Vandebriel, R.J.1    De Jong, W.H.2    Hendriks, J.J.A.3    Van Loveren, H.4
  • 48
    • 0031866496 scopus 로고    scopus 로고
    • Warbrick EV, Dearman RJ, Basketter DA, Gerberick GF, Ryan CA, Kimber I. 1998. Analysis of cytokine mRNA expression following repeated exposure of mice to chemical contact and respiratory allergens. J. Appl. Toxicol. 18: 205-213. DOI: 10.1002/(SICI)1099-1263(199805/ 06)18:3>205::AID- JAT502<3.0.CO;2-N
    • Warbrick EV, Dearman RJ, Basketter DA, Gerberick GF, Ryan CA, Kimber I. 1998. Analysis of cytokine mRNA expression following repeated exposure of mice to chemical contact and respiratory allergens. J. Appl. Toxicol. 18: 205-213. DOI: 10.1002/(SICI)1099-1263(199805/ 06)18:3>205::AID- JAT502<3.0.CO;2-N
  • 49
    • 0027534132 scopus 로고
    • Allergen-dependent induction of interleukin- 4 synthesis in vivo
    • Yang X, Hayglass KT. 1993. Allergen-dependent induction of interleukin- 4 synthesis in vivo. Immunology 78: 74-79.
    • (1993) Immunology , vol.78 , pp. 74-79
    • Yang, X.1    Hayglass, K.T.2
  • 50
    • 33751407004 scopus 로고    scopus 로고
    • Airway responses in Brown Norway rats following inhalation sensitization and challenge with trimellitic anhydride
    • DOI: 10.1093/ toxsci/kfl107
    • Zhang XD, Andrew ME, Hubbs AF, Siegel PD. 2006. Airway responses in Brown Norway rats following inhalation sensitization and challenge with trimellitic anhydride. Toxicol. Sci. 94: 322-329. DOI: 10.1093/ toxsci/kfl107
    • (2006) Toxicol. Sci , vol.94 , pp. 322-329
    • Zhang, X.D.1    Andrew, M.E.2    Hubbs, A.F.3    Siegel, P.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.