-
1
-
-
0028940007
-
p53 mutation in the myelodysplastic syndromes
-
Adamson D.J., Dawson A., Bennett B., King D.J. & Haites N.E. (1995) p53 mutation in the myelodysplastic syndromes. British Journal Haematology 89, 61-66.
-
(1995)
British Journal Haematology
, vol.89
, pp. 61-66
-
-
Adamson, D.J.1
Dawson, A.2
Bennett, B.3
King, D.J.4
Haites, N.E.5
-
2
-
-
79959525954
-
SNP array-based karyotyping: differences and similarities between aplastic anemia and hypocellular myelodysplastic syndromes
-
Afable M.G., Wlodarski M., Makishima H., Shaik M., Sekeres M.A., Tiu R.V., Kalaycio M., O'Keefe C.L. & Maciejewski J.P. (2011) SNP array-based karyotyping: differences and similarities between aplastic anemia and hypocellular myelodysplastic syndromes. Blood 117, 6876-6884.
-
(2011)
Blood
, vol.117
, pp. 6876-6884
-
-
Afable, M.G.1
Wlodarski, M.2
Makishima, H.3
Shaik, M.4
Sekeres, M.A.5
Tiu, R.V.6
Kalaycio, M.7
O'Keefe, C.L.8
Maciejewski, J.P.9
-
3
-
-
79952164235
-
Unraveling the molecular pathophysiology of myelodysplastic syndromes
-
Bejar R., Levine R. & Ebert B.L. (2011) Unraveling the molecular pathophysiology of myelodysplastic syndromes. Journal of Clinical Oncology 29, 504-515.
-
(2011)
Journal of Clinical Oncology
, vol.29
, pp. 504-515
-
-
Bejar, R.1
Levine, R.2
Ebert, B.L.3
-
4
-
-
79959794787
-
Clinical effect of point mutations in myelodysplastic syndromes
-
Bejar R., Stevenson K., Abdel-Wahab O., Galili N., Nilsson B., Garcia-Manero G., Kantarjian H., Raza A., Levine R.L., Neuberg D. & Ebert B.L. (2011) Clinical effect of point mutations in myelodysplastic syndromes. New England Journal of Medicine 364, 2496-2506.
-
(2011)
New England Journal of Medicine
, vol.364
, pp. 2496-2506
-
-
Bejar, R.1
Stevenson, K.2
Abdel-Wahab, O.3
Galili, N.4
Nilsson, B.5
Garcia-Manero, G.6
Kantarjian, H.7
Raza, A.8
Levine, R.L.9
Neuberg, D.10
Ebert, B.L.11
-
5
-
-
10544255085
-
Microsatellite instability and p53 mutations in therapy-related leukemia suggest mutator phenotype
-
Ben-Yehuda D., Krichevsky S., Caspi O., Rund D., Polliack A., Abeliovich D., Zelig O., Yahalom V., Paltiel O., Or R., Peretz T., Ben-Neriah S., Yehuda O. & Rachmilewitz E.A. (1996) Microsatellite instability and p53 mutations in therapy-related leukemia suggest mutator phenotype. Blood 88, 4296.
-
(1996)
Blood
, vol.88
, pp. 4296
-
-
Ben-Yehuda, D.1
Krichevsky, S.2
Caspi, O.3
Rund, D.4
Polliack, A.5
Abeliovich, D.6
Zelig, O.7
Yahalom, V.8
Paltiel, O.9
Or, R.10
Peretz, T.11
Ben-Neriah, S.12
Yehuda, O.13
Rachmilewitz, E.A.14
-
6
-
-
0036113177
-
Expression and prognostic significance of Bcl-2 family proteins in myelodysplastic syndromes
-
Boudard D., Vasselon C., Bertheas M.F., Jaubert J., Mounier C., Reynaud J., Viallet A., Chautard S., Guyotat D. & Campos L. (2002) Expression and prognostic significance of Bcl-2 family proteins in myelodysplastic syndromes. American Journal of Hematology 70, 115-125.
-
(2002)
American Journal of Hematology
, vol.70
, pp. 115-125
-
-
Boudard, D.1
Vasselon, C.2
Bertheas, M.F.3
Jaubert, J.4
Mounier, C.5
Reynaud, J.6
Viallet, A.7
Chautard, S.8
Guyotat, D.9
Campos, L.10
-
7
-
-
68049129840
-
Increase of telomerase activity and hTERT expression in myelodysplastic syndromes
-
Briatore F., Barrera G., Pizzimenti S., Toaldo C., Casa C.D., Laurora S., Pettazzoni P., Dianzani M.U. & Ferrero D. (2009) Increase of telomerase activity and hTERT expression in myelodysplastic syndromes. Cancer Biology and Therapeutics 8, 883-889.
-
(2009)
Cancer Biology and Therapeutics
, vol.8
, pp. 883-889
-
-
Briatore, F.1
Barrera, G.2
Pizzimenti, S.3
Toaldo, C.4
Casa, C.D.5
Laurora, S.6
Pettazzoni, P.7
Dianzani, M.U.8
Ferrero, D.9
-
8
-
-
0038011942
-
Significant correlation between the degree of WT1 expression and the International Prognostic Scoring System Score in patients with myelodysplastic syndromes
-
Piedmont Study Group on Myelodysplastic Syndromes..
-
Cilloni D., Gottardi E., Messa F., Fava M., Scaravaglio P., Bertini M., Girotto M., Marinone C., Ferrero D., Gallamini A., Levis A. & Saglio G.Piedmont Study Group on Myelodysplastic Syndromes. (2003) Significant correlation between the degree of WT1 expression and the International Prognostic Scoring System Score in patients with myelodysplastic syndromes. Journal of Clinical Oncology 21, 1988-1995.
-
(2003)
Journal of Clinical Oncology
, vol.21
, pp. 1988-1995
-
-
Cilloni, D.1
Gottardi, E.2
Messa, F.3
Fava, M.4
Scaravaglio, P.5
Bertini, M.6
Girotto, M.7
Marinone, C.8
Ferrero, D.9
Gallamini, A.10
Levis, A.11
Saglio, G.12
-
9
-
-
70349643737
-
Low RPS14 expression is common in myelodysplastic syndromes without 5q-aberration and defines a subgroup of patients with prolonged survival
-
Czibere A., Burns I., Junge B., Singh R., Kobbe G., Haas R. & Germing U. (2009) Low RPS14 expression is common in myelodysplastic syndromes without 5q-aberration and defines a subgroup of patients with prolonged survival. Haematologica 94, 1453-1455.
-
(2009)
Haematologica
, vol.94
, pp. 1453-1455
-
-
Czibere, A.1
Burns, I.2
Junge, B.3
Singh, R.4
Kobbe, G.5
Haas, R.6
Germing, U.7
-
10
-
-
0032171391
-
Bcl-2 expression by myeloid precursors in myelodysplastic syndromes: impact on disease progression
-
Davis R.E. & Greenberg P.L. (1998) Bcl-2 expression by myeloid precursors in myelodysplastic syndromes: impact on disease progression. Leukemia Research 22, 767-777.
-
(1998)
Leukemia Research
, vol.22
, pp. 767-777
-
-
Davis, R.E.1
Greenberg, P.L.2
-
11
-
-
77955715121
-
Mutation analysis for RUNX1, MLL-PTD, FLT3-ITD, NPM1 and NRAS in 269 patients with MDS or secondary AML
-
Dicker F., Haferlach C., Sundermann J., Wendland N., Weiss T., Kern W., Haferlach T. & Schnittger S. (2010) Mutation analysis for RUNX1, MLL-PTD, FLT3-ITD, NPM1 and NRAS in 269 patients with MDS or secondary AML. Leukemia 24, 1528-1532.
-
(2010)
Leukemia
, vol.24
, pp. 1528-1532
-
-
Dicker, F.1
Haferlach, C.2
Sundermann, J.3
Wendland, N.4
Weiss, T.5
Kern, W.6
Haferlach, T.7
Schnittger, S.8
-
12
-
-
38349088899
-
Identification of RPS14 as a 5q-syndrome gene by RNA interference screen
-
Ebert B.L., Pretz J., Bosco J., Chang C.Y., Tamayo P., Galili N., Raza A., Root D.E., Attar E., Ellis S.R. & Golub T.R. (2008) Identification of RPS14 as a 5q-syndrome gene by RNA interference screen. Nature 451, 335-339.
-
(2008)
Nature
, vol.451
, pp. 335-339
-
-
Ebert, B.L.1
Pretz, J.2
Bosco, J.3
Chang, C.Y.4
Tamayo, P.5
Galili, N.6
Raza, A.7
Root, D.E.8
Attar, E.9
Ellis, S.R.10
Golub, T.R.11
-
13
-
-
70350720044
-
MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation
-
Figueroa M.E., Skrabanek L., Li Y., Jiemjit A., Fandy T.E., Paietta E., Fernandez H., Tallman M.S., Greally J.M., Carraway H., Licht J.D., Gore S.D. & Melnick A. (2009) MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation. Blood 114, 3448-3458.
-
(2009)
Blood
, vol.114
, pp. 3448-3458
-
-
Figueroa, M.E.1
Skrabanek, L.2
Li, Y.3
Jiemjit, A.4
Fandy, T.E.5
Paietta, E.6
Fernandez, H.7
Tallman, M.S.8
Greally, J.M.9
Carraway, H.10
Licht, J.D.11
Gore, S.D.12
Melnick, A.13
-
14
-
-
38949123096
-
Chromosomal lesions and uniparental disomy detected by SNP arrays in MDS, MDS/MPD, and MDS-derived AML
-
Gondek L.P., Tiu R., O'Keefe C.L., Sekeres M.A., Theil K.S. & Maciejewski J.P. (2008) Chromosomal lesions and uniparental disomy detected by SNP arrays in MDS, MDS/MPD, and MDS-derived AML. Blood 111, 1534-1542.
-
(2008)
Blood
, vol.111
, pp. 1534-1542
-
-
Gondek, L.P.1
Tiu, R.2
O'Keefe, C.L.3
Sekeres, M.A.4
Theil, K.S.5
Maciejewski, J.P.6
-
15
-
-
84928625307
-
Clinical and prognostic characterization of myelodysplastic syndrome
-
(ed. P.L. Greenberg), Cambridge University Press, Cambridge, England.
-
Greenberg P.L. (2006a) Clinical and prognostic characterization of myelodysplastic syndrome. In: Myelodysplastic Syndromes: Clinical and Biological Advances (ed. P.L. Greenberg ), 1-32. Cambridge University Press, Cambridge, England.
-
(2006)
Myelodysplastic Syndromes: Clinical and Biological Advances
, pp. 1-32
-
-
Greenberg, P.L.1
-
16
-
-
84928639100
-
Pathogenetic mechanisms underlying myelodysplastic syndrome
-
(ed. P.L. Greenberg), Cambridge University Press, Cambridge, England.
-
Greenberg P.L. (2006b) Pathogenetic mechanisms underlying myelodysplastic syndrome. In: Myelodysplastic Syndromes: Clinical and Biological Advances (ed. P.L. Greenberg ), 63-94. Cambridge University Press, Cambridge, England.
-
(2006)
Myelodysplastic Syndromes: Clinical and Biological Advances
, pp. 63-94
-
-
Greenberg, P.L.1
-
17
-
-
0030897009
-
International scoring system for evaluating prognosis in myelodysplastic syndromes
-
Greenberg P., Cox C., Le Beau M.M., Fenaux P., Morel P., Sanz G., Sanz M., Vallespi T., Hamblin T., Oscier D., Ohyashiki K., Toyama K., Aul C., Mufti G. & Bennett J. (1997) International scoring system for evaluating prognosis in myelodysplastic syndromes. Blood 89, 2079-2088.
-
(1997)
Blood
, vol.89
, pp. 2079-2088
-
-
Greenberg, P.1
Cox, C.2
Le Beau, M.M.3
Fenaux, P.4
Morel, P.5
Sanz, G.6
Sanz, M.7
Vallespi, T.8
Hamblin, T.9
Oscier, D.10
Ohyashiki, K.11
Toyama, K.12
Aul, C.13
Mufti, G.14
Bennett, J.15
-
18
-
-
83055173257
-
Revised International Prognostic Scoring System (IPSS-R), developed by the International Prognostic Working Group for Prognosis in MDS (IWG-PM)
-
Greenberg P., Tuechler H., Schanz J., Sole F., Bennett J.M., Garcia-Manero G., Levis A., Malcovati L., Cazzola M., Sanz G., Cermak J., Fonatsch C., Le Beau M., Slovak M., Krieger O., Luebbert M., Magalhaes S., Miyazaki Y., Pfeilstoecker M., Sekeres M., Maciejewski J., Stauder R., Tauro S., van de Loosdrecht A., Germing U., Fenaux P. & Haase D. (2011) Revised International Prognostic Scoring System (IPSS-R), developed by the International Prognostic Working Group for Prognosis in MDS (IWG-PM). Leukemia Research 35(Suppl 1), S6.
-
(2011)
Leukemia Research
, vol.35
, Issue.SUPPL. 1
-
-
Greenberg, P.1
Tuechler, H.2
Schanz, J.3
Sole, F.4
Bennett, J.M.5
Garcia-Manero, G.6
Levis, A.7
Malcovati, L.8
Cazzola, M.9
Sanz, G.10
Cermak, J.11
Fonatsch, C.12
Le Beau, M.13
Slovak, M.14
Krieger, O.15
Luebbert, M.16
Magalhaes, S.17
Miyazaki, Y.18
Pfeilstoecker, M.19
Sekeres, M.20
Maciejewski, J.21
Stauder, R.22
Tauro, S.23
van de Loosdrecht, A.24
Germing, U.25
Fenaux, P.26
Haase, D.27
more..
-
19
-
-
1542373639
-
High incidence of somatic mutations in the AML1/RUNX1 gene in myelodysplastic syndrome and low blast percentage myeloid leukemia with myelodysplasia
-
Harada H., Harada Y., Niimi H., Kyo T., Kimura A. & Inaba T. (2004) High incidence of somatic mutations in the AML1/RUNX1 gene in myelodysplastic syndrome and low blast percentage myeloid leukemia with myelodysplasia. Blood 103, 2316-2324.
-
(2004)
Blood
, vol.103
, pp. 2316-2324
-
-
Harada, H.1
Harada, Y.2
Niimi, H.3
Kyo, T.4
Kimura, A.5
Inaba, T.6
-
20
-
-
0032868343
-
Distinct genetic involvement of the TP53 gene in therapy-related leukemia and myelodysplasia with chromosomal losses of Nos 5 and/or 7 and its possible relationship to replication error phenotype
-
Horiike S., Misawa S., Kaneko H., Sasai Y., Kobayashi M., Fujii H., Tanaka S., Yagita M., Abe T., Kashima K. & Taniwaki M. (1999) Distinct genetic involvement of the TP53 gene in therapy-related leukemia and myelodysplasia with chromosomal losses of Nos 5 and/or 7 and its possible relationship to replication error phenotype. Leukemia 13, 1235.
-
(1999)
Leukemia
, vol.13
, pp. 1235
-
-
Horiike, S.1
Misawa, S.2
Kaneko, H.3
Sasai, Y.4
Kobayashi, M.5
Fujii, H.6
Tanaka, S.7
Yagita, M.8
Abe, T.9
Kashima, K.10
Taniwaki, M.11
-
21
-
-
0037409886
-
Configuration of the TP53 gene as an independent prognostic parameter of myelodysplastic syndrome
-
Horiike S., Kita-Sasai Y., Nakao M. & Taniwaki M. (2003) Configuration of the TP53 gene as an independent prognostic parameter of myelodysplastic syndrome. Leukaemia & Lymphoma 44, 915-922.
-
(2003)
Leukaemia & Lymphoma
, vol.44
, pp. 915-922
-
-
Horiike, S.1
Kita-Sasai, Y.2
Nakao, M.3
Taniwaki, M.4
-
22
-
-
77950529126
-
Epigenetic changes in the myelodysplastic syndrome
-
Issa P. (2010) Epigenetic changes in the myelodysplastic syndrome. Hematology/oncology Clinics of North America 24, 317-330.
-
(2010)
Hematology/oncology Clinics of North America
, vol.24
, pp. 317-330
-
-
Issa, P.1
-
23
-
-
79956291339
-
TP53 mutations in low-risk myelodysplastic syndromes with del(5q) predict disease progression
-
Jädersten M., Saft L., Smith A., Kulasekararaj A., Pomplun S., Göhring G., Hedlund A., Hast R., Schlegelberger B., Porwit A., Hellström-Lindberg E. & Mufti G.J. (2011) TP53 mutations in low-risk myelodysplastic syndromes with del(5q) predict disease progression. Journal of Clinical Oncology 29, 1971-1979.
-
(2011)
Journal of Clinical Oncology
, vol.29
, pp. 1971-1979
-
-
Jädersten, M.1
Saft, L.2
Smith, A.3
Kulasekararaj, A.4
Pomplun, S.5
Göhring, G.6
Hedlund, A.7
Hast, R.8
Schlegelberger, B.9
Porwit, A.10
Hellström-Lindberg, E.11
Mufti, G.J.12
-
24
-
-
67650588639
-
Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms
-
Jankowska A.M., Szpurka H., Tiu R.V., Makishima H., Afable M., Huh J., O'Keefe C.L., Ganetzky R., McDevitt M.A. & Maciejewski J.P. (2009) Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms. Blood 113, 6403-6410.
-
(2009)
Blood
, vol.113
, pp. 6403-6410
-
-
Jankowska, A.M.1
Szpurka, H.2
Tiu, R.V.3
Makishima, H.4
Afable, M.5
Huh, J.6
O'Keefe, C.L.7
Ganetzky, R.8
McDevitt, M.A.9
Maciejewski, J.P.10
-
26
-
-
0035725856
-
International prognostic scoring system and TP53 mutations are independent prognostic indicators for patients with myelodysplastic syndrome
-
Kita-Sasai Y., Horiike S., Misawa S., Kaneko H., Kobayashi M., Nakao M., Nakagawa H., Fujii H. & Taniwaki M. (2001) International prognostic scoring system and TP53 mutations are independent prognostic indicators for patients with myelodysplastic syndrome. British Journal Haematology 115, 309-312.
-
(2001)
British Journal Haematology
, vol.115
, pp. 309-312
-
-
Kita-Sasai, Y.1
Horiike, S.2
Misawa, S.3
Kaneko, H.4
Kobayashi, M.5
Nakao, M.6
Nakagawa, H.7
Fujii, H.8
Taniwaki, M.9
-
27
-
-
70350438115
-
TET2 mutation is an independent favorable prognostic factor in myelodysplastic syndromes
-
Kosmider O., Gelsi-Boyer V., Cheok M., Grabar S., Della-Valle V., Picard F., Viguie′ F., Quesnel B., Beyne-Rauzy O., Solary E., Vey N., Hunault-Berger M., Fenaux P., Mansat-De Mas V., Delabesse E., Guardiola P., Lacombe C., Vainchenker W., Preudhomme C., Dreyfus F., Bernard O.A., Birnbaum D. & Fontenay M. (2009) TET2 mutation is an independent favorable prognostic factor in myelodysplastic syndromes. Blood 114, 3285-3291.
-
(2009)
Blood
, vol.114
, pp. 3285-3291
-
-
Kosmider, O.1
Gelsi-Boyer, V.2
Cheok, M.3
Grabar, S.4
Della-Valle, V.5
Picard, F.6
Viguie′, F.7
Quesnel, B.8
Beyne-Rauzy, O.9
Solary, E.10
Vey, N.11
Hunault-Berger, M.12
Fenaux, P.13
Mansat-De Mas, V.14
Delabesse, E.15
Guardiola, P.16
Lacombe, C.17
Vainchenker, W.18
Preudhomme, C.19
Dreyfus, F.20
Bernard, O.A.21
Birnbaum, D.22
Fontenay, M.23
more..
-
28
-
-
76649089645
-
Telomere shortening and chromosomal instability in myelodysplastic syndromes
-
Lange K., Holm L., Vang Nielsen K., Hahn A., Hofmann W., Kreipe H., Schlegelberger B. & Göhring G. (2010) Telomere shortening and chromosomal instability in myelodysplastic syndromes. Genes Chromosomes Cancer 49, 260-269.
-
(2010)
Genes Chromosomes Cancer
, vol.49
, pp. 260-269
-
-
Lange, K.1
Holm, L.2
Vang Nielsen, K.3
Hahn, A.4
Hofmann, W.5
Kreipe, H.6
Schlegelberger, B.7
Göhring, G.8
-
29
-
-
78651307662
-
Impact of adjunct cytogenetic abnormalities for prognostic stratification in patients with myelodysplastic syndrome and deletion 5q
-
Mallo M., Cervera J., Schanz J., Such E., García-Manero G., Luño E., Steidl C., Espinet B., Vallespí T., Germing U., Blum S., Ohyashiki K., Grau J., Pfeilstöcker M., Hernández J.M., Noesslinger T., Giagounidis A., Aul C., Calasanz M.J., Martín M.L., Valent P., Collado R., Haferlach C., Fonatsch C., Lübbert M., Stauder R., Hildebrandt B., Krieger O., Pedro C., Arenillas L., Sanz M.Á., Valencia A., Florensa L., Sanz G.F., Haase D. & Solé F. (2011) Impact of adjunct cytogenetic abnormalities for prognostic stratification in patients with myelodysplastic syndrome and deletion 5q. Leukemia 25, 110-120.
-
(2011)
Leukemia
, vol.25
, pp. 110-120
-
-
Mallo, M.1
Cervera, J.2
Schanz, J.3
Such, E.4
García-Manero, G.5
Luño, E.6
Steidl, C.7
Espinet, B.8
Vallespí, T.9
Germing, U.10
Blum, S.11
Ohyashiki, K.12
Grau, J.13
Pfeilstöcker, M.14
Hernández, J.M.15
Noesslinger, T.16
Giagounidis, A.17
Aul, C.18
Calasanz, M.J.19
Martín, M.L.20
Valent, P.21
Collado, R.22
Haferlach, C.23
Fonatsch, C.24
Lübbert, M.25
Stauder, R.26
Hildebrandt, B.27
Krieger, O.28
Pedro, C.29
Arenillas, L.30
Sanz, M.Á.31
Valencia, A.32
Florensa, L.33
Sanz, G.F.34
Haase, D.35
Solé, F.36
more..
-
30
-
-
70349249936
-
Microarray-based classifiers and prognosis models identify subgroups with distinct clinical outcomes and high risk of AML transformation of myelodysplastic syndrome
-
Mills K., Kohlmann A., Williams P.M., Wieczorek L., Liu W.M., Li R., Wei W., Bowen D.T., Loeffler H., Hernandez J.M., Hofmann W.K. & Haferlach T. (2009) Microarray-based classifiers and prognosis models identify subgroups with distinct clinical outcomes and high risk of AML transformation of myelodysplastic syndrome. Blood 114, 1063-1072.
-
(2009)
Blood
, vol.114
, pp. 1063-1072
-
-
Mills, K.1
Kohlmann, A.2
Williams, P.M.3
Wieczorek, L.4
Liu, W.M.5
Li, R.6
Wei, W.7
Bowen, D.T.8
Loeffler, H.9
Hernandez, J.M.10
Hofmann, W.K.11
Haferlach, T.12
-
31
-
-
0029619252
-
Mutations of the p53 gene in myelodysplastic syndrome and overt leukemia
-
Mori N., Hidai H., Yokota J., Okada M., Motoji T., Oshimi K. & Mizoguchi H. (1995) Mutations of the p53 gene in myelodysplastic syndrome and overt leukemia. Leukemia Research 19, 869.
-
(1995)
Leukemia Research
, vol.19
, pp. 869
-
-
Mori, N.1
Hidai, H.2
Yokota, J.3
Okada, M.4
Motoji, T.5
Oshimi, K.6
Mizoguchi, H.7
-
32
-
-
3042541853
-
Novel loss-of-function mutations of the haematopoiesis-related transcription factor, acute myeloid leukaemia 1/runt-related transcription factor 1, detected in acute myeloblastic leukaemia and myelodysplastic syndrome
-
Nakao M., Horiike S., Fukushima-Nakase Y., Nishimura M., Fujita Y., Taniwaki M. & Okuda T. (2004) Novel loss-of-function mutations of the haematopoiesis-related transcription factor, acute myeloid leukaemia 1/runt-related transcription factor 1, detected in acute myeloblastic leukaemia and myelodysplastic syndrome. British Journal Haematology 125, 709-719.
-
(2004)
British Journal Haematology
, vol.125
, pp. 709-719
-
-
Nakao, M.1
Horiike, S.2
Fukushima-Nakase, Y.3
Nishimura, M.4
Fujita, Y.5
Taniwaki, M.6
Okuda, T.7
-
33
-
-
0028210052
-
Mutations in the ras proto-oncogenes in patients with myelodysplastic syndromes
-
Neubauer A., Greenberg P., Negrin R., Ginzton N. & Liu E. (1994) Mutations in the ras proto-oncogenes in patients with myelodysplastic syndromes. Leukemia 8, 638.
-
(1994)
Leukemia
, vol.8
, pp. 638
-
-
Neubauer, A.1
Greenberg, P.2
Negrin, R.3
Ginzton, N.4
Liu, E.5
-
34
-
-
0032902504
-
Telomere stability is frequently impaired in high-risk groups of patients with myelodysplastic syndromes
-
Ohyashiki J.H., Iwama H., Yahata N., Ando K., Hayashi S., Shay J.W. & Ohyashiki K. (1999) Telomere stability is frequently impaired in high-risk groups of patients with myelodysplastic syndromes. Clinical Cancer Research 5, 1155-1160.
-
(1999)
Clinical Cancer Research
, vol.5
, pp. 1155-1160
-
-
Ohyashiki, J.H.1
Iwama, H.2
Yahata, N.3
Ando, K.4
Hayashi, S.5
Shay, J.W.6
Ohyashiki, K.7
-
36
-
-
17344371122
-
RAS, FMS and p53 mutations and poor clinical outcome in myelodysplasias: a 10-year follow-up
-
Padua R.A., Guinn B., Al-Sabah A.I., Smith M., Taylor C., Pettersson T., Ridge S., Carter G., White D., Oscier D., Chevret S. & West R. (1998) RAS, FMS and p53 mutations and poor clinical outcome in myelodysplasias: a 10-year follow-up. Leukemia 12, 887-892.
-
(1998)
Leukemia
, vol.12
, pp. 887-892
-
-
Padua, R.A.1
Guinn, B.2
Al-Sabah, A.I.3
Smith, M.4
Taylor, C.5
Pettersson, T.6
Ridge, S.7
Carter, G.8
White, D.9
Oscier, D.10
Chevret, S.11
West, R.12
-
37
-
-
80054010617
-
Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts
-
Papaemmanuil E., Cazzola M., Boultwood J., Malcovati L., Vyas P., Bowen D., Pellagatti A., Wainscoat J.S., Hellstrom-Lindberg E., Gambacorti-Passerini C., Godfrey A.L., Rapado I., Cvejic A., Rance R., McGee C., Ellis P., Mudie L.J., Stephens P.J., McLaren S., Massie C.E., Tarpey P.S., Varela I., Nik-Zainal S., Davies H.R., Shlien A., Jones D., Raine K., Hinton J., Butler A.P., Teague J.W., Baxter E.J., Score J., Galli A., Della Porta M.G., Travaglino E., Groves M., Tauro S., Munshi N.C., Anderson K.C., El-Naggar A., Fischer A., Mustonen V., Warren A.J., Cross N.C., Green A.R., Futreal P.A., Stratton M.R. & Campbell P.J. (2011) Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts. New England Journal of Medicine 365, 1384-1395.
-
(2011)
New England Journal of Medicine
, vol.365
, pp. 1384-1395
-
-
Papaemmanuil, E.1
Cazzola, M.2
Boultwood, J.3
Malcovati, L.4
Vyas, P.5
Bowen, D.6
Pellagatti, A.7
Wainscoat, J.S.8
Hellstrom-Lindberg, E.9
Gambacorti-Passerini, C.10
Godfrey, A.L.11
Rapado, I.12
Cvejic, A.13
Rance, R.14
McGee, C.15
Ellis, P.16
Mudie, L.J.17
Stephens, P.J.18
McLaren, S.19
Massie, C.E.20
Tarpey, P.S.21
Varela, I.22
Nik-Zainal, S.23
Davies, H.R.24
Shlien, A.25
Jones, D.26
Raine, K.27
Hinton, J.28
Butler, A.P.29
Teague, J.W.30
Baxter, E.J.31
Score, J.32
Galli, A.33
Della Porta, M.G.34
Travaglino, E.35
Groves, M.36
Tauro, S.37
Munshi, N.C.38
Anderson, K.C.39
El-Naggar, A.40
Fischer, A.41
Mustonen, V.42
Warren, A.J.43
Cross, N.C.44
Green, A.R.45
Futreal, P.A.46
Stratton, M.R.47
Campbell, P.J.48
more..
-
38
-
-
0027181645
-
N-ras mutations are associated with poor prognosis and increased risk of leukemia in myelodysplastic syndrome
-
Paquette R.L., Landaw E., Pierre R.V., Kahan J., Lübbert M., Lazcano O., Isaac G., McCormick F. & Koeffler H.P. (1993) N-ras mutations are associated with poor prognosis and increased risk of leukemia in myelodysplastic syndrome. Blood 82, 590-599.
-
(1993)
Blood
, vol.82
, pp. 590-599
-
-
Paquette, R.L.1
Landaw, E.2
Pierre, R.V.3
Kahan, J.4
Lübbert, M.5
Lazcano, O.6
Isaac, G.7
McCormick, F.8
Koeffler, H.P.9
-
39
-
-
0034551738
-
The role of apoptosis, proliferation, and the Bcl-2-related proteins in the myelodysplastic syndromes and acute myeloid leukemia secondary to MDS
-
Parker J.E., Mufti G., Rasool F., Mijovic A., Devereux S. & Pagliuca A. (2000) The role of apoptosis, proliferation, and the Bcl-2-related proteins in the myelodysplastic syndromes and acute myeloid leukemia secondary to MDS. Blood 96, 3932-3938.
-
(2000)
Blood
, vol.96
, pp. 3932-3938
-
-
Parker, J.E.1
Mufti, G.2
Rasool, F.3
Mijovic, A.4
Devereux, S.5
Pagliuca, A.6
-
40
-
-
77950943405
-
Deregulated gene expression pathways in myelodysplastic syndrome hematopoietic stem cells
-
Pellagatti A., Cazzola M., Giagounidis A., Perry J., Malcovati L., Della Porta M.G., Jädersten M., Killick S., Verma A., Norbury C.J., Hellström-Lindberg E., Wainscoat J.S. & Boultwood J. (2010a) Deregulated gene expression pathways in myelodysplastic syndrome hematopoietic stem cells. Leukemia 24, 756-764.
-
(2010)
Leukemia
, vol.24
, pp. 756-764
-
-
Pellagatti, A.1
Cazzola, M.2
Giagounidis, A.3
Perry, J.4
Malcovati, L.5
Della Porta, M.G.6
Jädersten, M.7
Killick, S.8
Verma, A.9
Norbury, C.J.10
Hellström-Lindberg, E.11
Wainscoat, J.S.12
Boultwood, J.13
-
41
-
-
77950988337
-
Induction of p53 and up-regulation of the p53 pathway in the human 5q-syndrome
-
Pellagatti A., Marafioti T., Paterson J.C., Barlow J.L., Drynan L.F., Giagounidis A., Pileri S.A., Cazzola M., McKenzie A.N., Wainscoat J.S. & Boultwood J. (2010b) Induction of p53 and up-regulation of the p53 pathway in the human 5q-syndrome. Blood 115, 2721-2723.
-
(2010)
Blood
, vol.115
, pp. 2721-2723
-
-
Pellagatti, A.1
Marafioti, T.2
Paterson, J.C.3
Barlow, J.L.4
Drynan, L.F.5
Giagounidis, A.6
Pileri, S.A.7
Cazzola, M.8
McKenzie, A.N.9
Wainscoat, J.S.10
Boultwood, J.11
-
42
-
-
80053503649
-
Marked down-regulation of nucleophosmin-1 is associated with advanced del(5q) myelodysplastic syndrome
-
Pellagatti A., Cazzola M., Giagounidis A., Perry J., Malcovati L., Della Porta M., Jadersten M., Killick S., Vyas P., Hellstrom-Lindberg E., Wainscoat J. & Boultwood J. (2011) Marked down-regulation of nucleophosmin-1 is associated with advanced del(5q) myelodysplastic syndrome. British Journal of Haematology 155, 272-274.
-
(2011)
British Journal of Haematology
, vol.155
, pp. 272-274
-
-
Pellagatti, A.1
Cazzola, M.2
Giagounidis, A.3
Perry, J.4
Malcovati, L.5
Della Porta, M.6
Jadersten, M.7
Killick, S.8
Vyas, P.9
Hellstrom-Lindberg, E.10
Wainscoat, J.11
Boultwood, J.12
-
43
-
-
0032523011
-
Methylation of the p15(INK4b) gene in myelodysplastic syndromes is frequent and acquired during disease progression
-
Quesnel B., Guillerm G., Vereecque R., Wattel E., Preudhomme C., Bauters F., Vanrumbeke M. & Fenaux P. (1998) Methylation of the p15(INK4b) gene in myelodysplastic syndromes is frequent and acquired during disease progression. Blood 91, 2985-2990.
-
(1998)
Blood
, vol.91
, pp. 2985-2990
-
-
Quesnel, B.1
Guillerm, G.2
Vereecque, R.3
Wattel, E.4
Preudhomme, C.5
Bauters, F.6
Vanrumbeke, M.7
Fenaux, P.8
-
44
-
-
0029957664
-
Altered oncogene expression and apoptosis in myelodysplastic syndrome marrow cells
-
Rajapaksa R., Ginzton N., Rott L. & Greenberg P.L. (1996) Altered oncogene expression and apoptosis in myelodysplastic syndrome marrow cells. Blood 88, 4275-4287.
-
(1996)
Blood
, vol.88
, pp. 4275-4287
-
-
Rajapaksa, R.1
Ginzton, N.2
Rott, L.3
Greenberg, P.L.4
-
45
-
-
0025190309
-
FMS mutations in myelodysplastic, leukemic, and normal subjects
-
Ridge S.A., Worwood M., Oscier D., Jacobs A. & Padua RA. (1990) FMS mutations in myelodysplastic, leukemic, and normal subjects. Proceedings of the National Academy of Sciences of the United States of America 87, 1377.
-
(1990)
Proceedings of the National Academy of Sciences of the United States of America
, vol.87
, pp. 1377
-
-
Ridge, S.A.1
Worwood, M.2
Oscier, D.3
Jacobs, A.4
Padua, R.A.5
-
46
-
-
77955081371
-
Combined mutations of ASXL1, CBL, FLT3, IDH1, IDH2, JAK2, KRAS, NPM1, NRAS, RUNX1, TET2 and WT1 genes in myelodysplastic syndromes and acute myeloid leukemias
-
Rocquain J., Carbuccia N., Trouplin V., Raynaud S., Murati A., Nezri M., Tadrist Z., Olschwang S., Vey N., Birnbaum D., Gelsi-Boyer V. & Mozziconacci M.J. (2010) Combined mutations of ASXL1, CBL, FLT3, IDH1, IDH2, JAK2, KRAS, NPM1, NRAS, RUNX1, TET2 and WT1 genes in myelodysplastic syndromes and acute myeloid leukemias. Biomed Central Cancer 10, 401-408.
-
(2010)
Biomed Central Cancer
, vol.10
, pp. 401-408
-
-
Rocquain, J.1
Carbuccia, N.2
Trouplin, V.3
Raynaud, S.4
Murati, A.5
Nezri, M.6
Tadrist, Z.7
Olschwang, S.8
Vey, N.9
Birnbaum, D.10
Gelsi-Boyer, V.11
Mozziconacci, M.J.12
-
47
-
-
84858830672
-
A new comprehensive cytogenetic scoring system for primary myelodysplastic syndromes and oligoblastic AML following MDS derived from an international database merge
-
in press.
-
Schanz J., Tuechler H., Sole F., Mallo M., Luno E., Cervera J., Granada I., Hildebrandt B., Slovak M., Ohyashiki K., Steidl C., Fonatsch C., Pfeilstöcker M., Nösslinger T., Valent P., Giagounidis A., Aul C., Lübbert M., Stauder R., Krieger O., Garcia-Manero G., Faderl S., Pierce S., Le Beau M.M., Bennett J., Greenberg P., Germing U. & Haase D (2012) A new comprehensive cytogenetic scoring system for primary myelodysplastic syndromes and oligoblastic AML following MDS derived from an international database merge. J Clin Oncology, in press.
-
(2012)
J Clin Oncology
-
-
Schanz, J.1
Tuechler, H.2
Sole, F.3
Mallo, M.4
Luno, E.5
Cervera, J.6
Granada, I.7
Hildebrandt, B.8
Slovak, M.9
Ohyashiki, K.10
Steidl, C.11
Fonatsch, C.12
Pfeilstöcker, M.13
Nösslinger, T.14
Valent, P.15
Giagounidis, A.16
Aul, C.17
Lübbert, M.18
Stauder, R.19
Krieger, O.20
Garcia-Manero, G.21
Faderl, S.22
Pierce, S.23
Le Beau, M.M.24
Bennett, J.25
Greenberg, P.26
Germing, U.27
Haase, D.28
more..
-
48
-
-
1542503817
-
Acquisition of FLT3 or N-ras mutations is frequently associated with progression of myelodysplastic syndrome to acute myeloid leukemia
-
Shih L.Y., Huang C., Wang P.N., Wu J.H., Lin T.L., Dunn P. & Kuo M.C. (2004a) Acquisition of FLT3 or N-ras mutations is frequently associated with progression of myelodysplastic syndrome to acute myeloid leukemia. Leukemia 18, 466-475.
-
(2004)
Leukemia
, vol.18
, pp. 466-475
-
-
Shih, L.Y.1
Huang, C.2
Wang, P.N.3
Wu, J.H.4
Lin, T.L.5
Dunn, P.6
Kuo, M.C.7
-
49
-
-
4143053704
-
Internal tandem duplication of fms-like tyrosine kinase 3 is associated with poor outcome in patients with myelodysplastic syndrome
-
Shih L.Y., Lin T., Wang P.N., Wu J.H., Dunn P., Kuo M.C. & Huang C.F. (2004b) Internal tandem duplication of fms-like tyrosine kinase 3 is associated with poor outcome in patients with myelodysplastic syndrome. Cancer 101, 989-998.
-
(2004)
Cancer
, vol.101
, pp. 989-998
-
-
Shih, L.Y.1
Lin, T.2
Wang, P.N.3
Wu, J.H.4
Dunn, P.5
Kuo, M.C.6
Huang, C.F.7
-
50
-
-
74049098354
-
Relationship of differential gene expression profiles in CD34+ myelodysplastic syndrome marrow cells to disease subtype and progression
-
Sridhar K., Ross D., Tibshirani R., Butte A. & Greenberg P.L. (2009) Relationship of differential gene expression profiles in CD34+ myelodysplastic syndrome marrow cells to disease subtype and progression. Blood 114, 4847-4858.
-
(2009)
Blood
, vol.114
, pp. 4847-4858
-
-
Sridhar, K.1
Ross, D.2
Tibshirani, R.3
Butte, A.4
Greenberg, P.L.5
-
51
-
-
73849121794
-
Identification of miR-145 and miR-146a as mediators of the 5q-syndrome phenotype
-
Starczynowski D.T., Kuchenbauer F., Argiropoulos B., Sung S., Morin R., Muranyi A., Hirst M., Hogge D., Marra M., Wells R.A., Buckstein R., Lam W., Humphries R.K. & Karsan A. (2010) Identification of miR-145 and miR-146a as mediators of the 5q-syndrome phenotype. Nature Medicine 16, 49-58.
-
(2010)
Nature Medicine
, vol.16
, pp. 49-58
-
-
Starczynowski, D.T.1
Kuchenbauer, F.2
Argiropoulos, B.3
Sung, S.4
Morin, R.5
Muranyi, A.6
Hirst, M.7
Hogge, D.8
Marra, M.9
Wells, R.A.10
Buckstein, R.11
Lam, W.12
Humphries, R.K.13
Karsan, A.14
-
52
-
-
0027247412
-
Mutations of the p53 gene in myelodysplastic syndrome (MDS) and MDS-derived leukemia
-
Sugimoto K., Hirano N., Toyoshima H., Chiba S., Mano H., Takaku F., Yazaki Y. & Hirai H. (1993) Mutations of the p53 gene in myelodysplastic syndrome (MDS) and MDS-derived leukemia. Blood 81, 3022.
-
(1993)
Blood
, vol.81
, pp. 3022
-
-
Sugimoto, K.1
Hirano, N.2
Toyoshima, H.3
Chiba, S.4
Mano, H.5
Takaku, F.6
Yazaki, Y.7
Hirai, H.8
-
53
-
-
84984571820
-
p53 mutation in advanced stage of primary myelodysplastic syndrome
-
Tang J.L., Tien H., Lin M.T., Chen P.J. & Chen Y.C. (1998) p53 mutation in advanced stage of primary myelodysplastic syndrome. Anticancer Research 18, 3757.
-
(1998)
Anticancer Research
, vol.18
, pp. 3757
-
-
Tang, J.L.1
Tien, H.2
Lin, M.T.3
Chen, P.J.4
Chen, Y.C.5
-
54
-
-
79959317767
-
Prognostic significance of ASXL1 mutations in patients with myelodysplastic syndromes
-
Thol F., Friesen I., Damm F., Yun H., Weissinger E.M., Krauter J., Wagner K., Chaturvedi A., Sharma A., Wichmann M., Göhring G., Schumann C., Bug G., Ottmann O., Hofmann W.K., Schlegelberger B., Heuser M. & Ganser A. (2011) Prognostic significance of ASXL1 mutations in patients with myelodysplastic syndromes. Journal of Clinical Oncology 29, 2499-2506.
-
(2011)
Journal of Clinical Oncology
, vol.29
, pp. 2499-2506
-
-
Thol, F.1
Friesen, I.2
Damm, F.3
Yun, H.4
Weissinger, E.M.5
Krauter, J.6
Wagner, K.7
Chaturvedi, A.8
Sharma, A.9
Wichmann, M.10
Göhring, G.11
Schumann, C.12
Bug, G.13
Ottmann, O.14
Hofmann, W.K.15
Schlegelberger, B.16
Heuser, M.17
Ganser, A.18
-
55
-
-
0025276780
-
Mutation of the human FMS gene (M-CSF receptor) in myelodysplastic syndromes and acute myeloid leukemia
-
Tobal K., Pagliuca A., Bhatt B., Bailey N., Layton D. & Mufti G.J. (1990) Mutation of the human FMS gene (M-CSF receptor) in myelodysplastic syndromes and acute myeloid leukemia. Leukemia 4, 486.
-
(1990)
Leukemia
, vol.4
, pp. 486
-
-
Tobal, K.1
Pagliuca, A.2
Bhatt, B.3
Bailey, N.4
Layton, D.5
Mufti, G.J.6
-
56
-
-
70349256226
-
The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes
-
Vardiman J.W., Thiele J., Arber D.A., Brunning R.D., Borowitz M.J., Porwit A., Harris N.L., Le Beau M.M., Hellström-Lindberg E., Tefferi A. & Bloomfield C.D. (2009) The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. Blood 114, 937-951.
-
(2009)
Blood
, vol.114
, pp. 937-951
-
-
Vardiman, J.W.1
Thiele, J.2
Arber, D.A.3
Brunning, R.D.4
Borowitz, M.J.5
Porwit, A.6
Harris, N.L.7
Le Beau, M.M.8
Hellström-Lindberg, E.9
Tefferi, A.10
Bloomfield, C.D.11
-
57
-
-
79960255863
-
Recurrent DNMT3A mutations in patients with myelodysplastic syndromes
-
Walter M.J., Ding L., Shen D., Shao J., Grillot M., McLellan M., Fulton R., Schmidt H., Kalicki-Veizer J., O'Laughlin M., Kandoth C., Baty J., Westervelt P., DiPersio J.F., Mardis E.R., Wilson R.K., Ley T.J. & Graubert T.A. (2011) Recurrent DNMT3A mutations in patients with myelodysplastic syndromes. Leukemia 25, 1153-1158.
-
(2011)
Leukemia
, vol.25
, pp. 1153-1158
-
-
Walter, M.J.1
Ding, L.2
Shen, D.3
Shao, J.4
Grillot, M.5
McLellan, M.6
Fulton, R.7
Schmidt, H.8
Kalicki-Veizer, J.9
O'Laughlin, M.10
Kandoth, C.11
Baty, J.12
Westervelt, P.13
DiPersio, J.F.14
Mardis, E.R.15
Wilson, R.K.16
Ley, T.J.17
Graubert, T.A.18
-
58
-
-
0028172868
-
p53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies
-
Wattel E., Preudhomme C., Hecquet B., Anrumbeke M., Quesnel B., Dervite I., Morel P. & Fenaux P. (1994) p53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies. Blood 84, 3148.
-
(1994)
Blood
, vol.84
, pp. 3148
-
-
Wattel, E.1
Preudhomme, C.2
Hecquet, B.3
Anrumbeke, M.4
Quesnel, B.5
Dervite, I.6
Morel, P.7
Fenaux, P.8
-
59
-
-
80053900941
-
Frequent pathway mutations of splicing machinery in myelodysplasia
-
Yoshida K., Masashi Sanada M., Yuichi Shiraishi Y., Nowak D., Nagata Y., Yamamoto R., Sato Y., Sato-Otsubo A., Kon A., Nagasaki M., Chalkidis G., Suzuki Y., Shiosaka M., Kawahata R., Yamaguchi T., Otsu M., Obara N., Sakata-Yanagimoto M., Ishiyama K., Mori H., Nolte F., Hofmann W.K., Miyawaki S., Sugano S., Haferlach C., Koeffler H.P., Shih L.Y., Haferlach T., Chiba S., Nakauchi H., Miyano S. & Ogawa S. (2011) Frequent pathway mutations of splicing machinery in myelodysplasia. Nature 478, 64-69.
-
(2011)
Nature
, vol.478
, pp. 64-69
-
-
Yoshida, K.1
Masashi Sanada, M.2
Yuichi Shiraishi, Y.3
Nowak, D.4
Nagata, Y.5
Yamamoto, R.6
Sato, Y.7
Sato-Otsubo, A.8
Kon, A.9
Nagasaki, M.10
Chalkidis, G.11
Suzuki, Y.12
Shiosaka, M.13
Kawahata, R.14
Yamaguchi, T.15
Otsu, M.16
Obara, N.17
Sakata-Yanagimoto, M.18
Ishiyama, K.19
Mori, H.20
Nolte, F.21
Hofmann, W.K.22
Miyawaki, S.23
Sugano, S.24
Haferlach, C.25
Koeffler, H.P.26
Shih, L.Y.27
Haferlach, T.28
Chiba, S.29
Nakauchi, H.30
Miyano, S.31
Ogawa, S.32
more..
|