Venlafaxine loaded chitosan NPs for brain targeting: Pharmacokinetic and pharmacodynamic evaluation

Carbohydrate Polymers

Volumn 89, Issue 1, 2012, Pages 72-79

  Haque, Shadabul ^a,b   Md, Shadab ^a   Fazil, Mohammad ^a   Kumar, Manish ^c   Sahni, Jasjeet Kaur ^a   Ali, Javed ^a   Baboota, Sanjula ^a  

^a HAMDARD UNIVERSITY   (India)

^b RANBAXY RESEARCH LABORATORIES   (India)

^c JAWAHARLAL NEHRU UNIVERSITY   (India)

Author keywords

Biodistribution; Brain targeting; Chitosan; Confocal microscopy; Intranasal route; Venlafaxine

Indexed keywords

BIODISTRIBUTIONS; BRAIN TISSUE; BRAIN UPTAKE; CHITOSAN NANOPARTICLES; CONFOCAL LASER SCANNING MICROSCOPY; DRUG TRANSPORT; ENCAPSULATION EFFICIENCY; IN-VITRO; INTRANASAL; VENLAFAXINE;

CHITOSAN; CONFOCAL MICROSCOPY; DRUG PRODUCTS; ENCAPSULATION; ZETA POTENTIAL;

MULTILAYERS;

ANTIDEPRESSANT AGENT; CHITOSAN; CYCLOHEXANOL DERIVATIVE; NANOPARTICLE; VENLAFAXINE;

ANIMAL; ANIMAL BEHAVIOR; BRAIN; CHEMISTRY; DRUG EFFECTS; DRUG FORMULATION; FEMALE; IN VITRO STUDY; INTRANASAL DRUG ADMINISTRATION; MALE; METABOLISM; MOTOR ACTIVITY; NOSE MUCOSA; WISTAR RAT;

ADMINISTRATION, INTRANASAL; ANIMALS; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; BEHAVIOR, ANIMAL; BRAIN; CHITOSAN; CYCLOHEXANOLS; DRUG COMPOUNDING; FEMALE; IN VITRO TECHNIQUES; MALE; MOTOR ACTIVITY; NANOPARTICLES; NASAL MUCOSA; RATS, WISTAR;

EID: 84860214736     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2012.02.051     Document Type: Article

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