Steroids as central regulators of organismal development and lifespan

PLoS Biology

Volumn 10, Issue 4, 2012, Pages

  Lee, Siu Sylvia ^a   Schroeder, Frank C ^b  

^a Department of Molecular Biology and Genetics   (United States)

^b United States Department of Agriculture   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; CELL NUCLEUS RECEPTOR; DAFACHRONIC ACID; ENZYME; LIVER X RECEPTOR; PHEROMONE; PROTEIN DAF 12; PROTEIN DHS 16; STEROID; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR; CAENORHABDITIS ELEGANS PROTEIN; CELL RECEPTOR; CHOLESTANE DERIVATIVE; DAF 12 PROTEIN, C ELEGANS; DAF-12 PROTEIN, C ELEGANS; LIGAND;

ARTICLE; BIOSYNTHESIS; CAENORHABDITIS ELEGANS; DEVELOPMENT; DIAPAUSE; ENVIRONMENTAL FACTOR; GENE EXPRESSION; LIFESPAN; NEUROENDOCRINE SYSTEM; NONHUMAN; ORGANISMAL DEVELOPMENT; POPULATION DENSITY; PROTEIN FUNCTION; PROTEIN STRUCTURE; REGULATORY MECHANISM; REPRODUCTIVE DEVELOPMENT; STEROIDOGENESIS; ADAPTATION; ANIMAL; ENVIRONMENT; GROWTH, DEVELOPMENT AND AGING; LIFE EXPECTANCY; METABOLISM; PHYSIOLOGY;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; BIOSYNTHETIC PATHWAYS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CHOLESTENES; ENVIRONMENT; LIFE EXPECTANCY; LIGANDS; PHEROMONES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; STEROIDS;

EID: 84859992571     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1001307     Document Type: Article

References (29)

1. Hu P. J, (2007) Dauer. pp. 1-19 WormBook.
2. Kenyon C. J., The genetics of ageing. Nature 464: 504-512.
3. Golden J. W, Riddle D. L, (1982) A pheromone influences larval development in the nematode Caenorhabditis elegans. Science 218: 578-580.
4. Golden J. W, Riddle D. L, (1984) The Caenorhabditis elegans dauer larva: developmental effects of pheromone, food, and temperature. Dev Biol 102: 368-378.
5. Thomas J. H, Birnby D. A, Vowels J. J, (1993) Evidence for parallel processing of sensory information controlling dauer formation in Caenorhabditis elegans. Genetics 134: 1105-1117.
6. Vowels J. J, Thomas J. H, (1992) Genetic analysis of chemosensory control of dauer formation in Caenorhabditis elegans. Genetics 130: 105-123.
7. Gottlieb S, Ruvkun G, (1994) daf-2, daf-16 and daf-23: genetically interacting genes controlling Dauer formation in Caenorhabditis elegans. Genetics 137: 107-120.
8. Riddle D. L, Swanson M. M, Albert P. S, (1981) Interacting genes in nematode dauer larva formation. Nature 290: 668-671.
9. Patterson G. I, Padgett R. W, (2000) TGF beta-related pathways. Roles in Caenorhabditis elegans development. Trends Genet 16: 27-33.
10. Antebi A, Yeh W. H, Tait D, Hedgecock E. M, Riddle D. L, (2000) daf-12 encodes a nuclear receptor that regulates the dauer diapause and developmental age in C. elegans. Genes Dev 14: 1512-1527.
11. Albert P. S, Riddle D. L, (1988) Mutants of Caenorhabditis elegans that form dauer-like larvae. Dev Biol 126: 270-293.
12. Gerisch B, Weitzel C, Kober-Eisermann C, Rottiers V, Antebi A, (2001) A hormonal signaling pathway influencing C. elegans metabolism, reproductive development, and life span. Dev Cell 1: 841-851.
13. Jia K, Albert P. S, Riddle D. L, (2002) DAF-9, a cytochrome P450 regulating C. elegans larval development and adult longevity. Development 129: 221-231.
14. Gerisch B, Antebi A, (2004) Hormonal signals produced by DAF-9/cytochrome P450 regulate C. elegans dauer diapause in response to environmental cues. Development 131: 1765-1776.
15. Jeong P. Y, Jung M, Yim Y. H, Kim H, Park M, et al. (2005) Chemical structure and biological activity of the Caenorhabditis elegans dauer-inducing pheromone. Nature 433: 541-545.
16. Butcher R. A, Fujita M, Schroeder F. C, Clardy J, (2007) Small-molecule pheromones that control dauer development in Caenorhabditis elegans. Nat Chem Biol 3: 420-422.
17. Butcher R. A, Ragains J. R, Kim E, Clardy J, (2008) A potent dauer pheromone component in Caenorhabditis elegans that acts synergistically with other components. Proc Natl Acad Sci U S A 105: 14288-14292.
18. Pungaliya C, Srinivasan J, Fox B. W, Malik R. U, Ludewig A. H, et al. (2009) A shortcut to identifying small molecule signals that regulate behavior and development in Caenorhabditis elegans. Proc Natl Acad Sci U S A 106: 7708-7713.
19. Srinivasan J, Kaplan F, Ajredini R, Zachariah C, Alborn H. T, et al. (2008) A blend of small molecules regulates both mating and development in Caenorhabditis elegans. Nature 454: 1115-1118.
20. Kim K, Sato K, Shibuya M, Zeiger D. M, Butcher R. A, et al. (2009) Two chemoreceptors mediate developmental effects of dauer pheromone in C. elegans. Science 326: 994-998.
21. McGrath P. T, Xu Y, Ailion M, Garrison J. L, Butcher R. A, et al. Parallel evolution of domesticated Caenorhabditis species targets pheromone receptor genes. Nature 477: 321-325.
22. Motola D. L, Cummins C. L, Rottiers V, Sharma K. K, Li T, et al. (2006) Identification of ligands for DAF-12 that govern dauer formation and reproduction in C. elegans. Cell 124: 1209-1223.
23. Sommer R. J, Ogawa A., Hormone signaling and phenotypic plasticity in nematode development and evolution. Curr Biol 21: R758-R766.
24. Gerisch B, Rottiers V, Li D, Motola D. L, Cummins C. L, et al. (2007) A bile acid-like steroid modulates Caenorhabditis elegans lifespan through nuclear receptor signaling. Proc Natl Acad Sci U S A 104: 5014-5019.
25. Rottiers V, Motola D. L, Gerisch B, Cummins C. L, Nishiwaki K, et al. (2006) Hormonal control of C. elegans dauer formation and life span by a Rieske-like oxygenase. Dev Cell 10: 473-482.
26. Dumas K. J, Guo C, Wang X, Burkhart K. B, Adams E. J, et al. Functional divergence of dafachronic acid pathways in the control of C. elegans development and lifespan. Dev Biol 340: 605-612.
27. Patel D. S, Fang L. L, Svy D. K, Ruvkun G, Li W, (2008) Genetic identification of HSD-1, a conserved steroidogenic enzyme that directs larval development in Caenorhabditis elegans. Development 135: 2239-2249.
28. Kimura K. D, Tissenbaum H. A, Liu Y, Ruvkun G, (1997) daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 277: 942-946.
29. Shaw W. M, Luo S, Landis J, Ashraf J, Murphy C. T, (2007) The C. elegans TGF-beta Dauer pathway regulates longevity via insulin signaling. Curr Biol 17: 1635-1645.