-
1
-
-
0014308111
-
How does the ribosome work? A hypothesis based on the two subunit construction of the ribosome
-
Spirin AS (1968) How does the ribosome work? A hypothesis based on the two subunit construction of the ribosome. Curr Mod Biol 2:115-127.
-
(1968)
Curr Mod Biol
, vol.2
, pp. 115-127
-
-
Spirin, A.S.1
-
2
-
-
0014422075
-
Translocation in protein synthesis: A hybrid structure model
-
Bretscher MS (1968) Translocation in protein synthesis: A hybrid structure model. Nature 218:675-677.
-
(1968)
Nature
, vol.218
, pp. 675-677
-
-
Bretscher, M.S.1
-
3
-
-
77449133028
-
Elongation in translation as a dynamic interaction among the ribosome, tRNA, and elongation factors EF-G and EF-Tu
-
Agirrezabala X, Frank J (2009) Elongation in translation as a dynamic interaction among the ribosome, tRNA, and elongation factors EF-G and EF-Tu. Q Rev Biophys 42:159-200.
-
(2009)
Q Rev Biophys
, vol.42
, pp. 159-200
-
-
Agirrezabala, X.1
Frank, J.2
-
4
-
-
38049178477
-
The process of mRNA-tRNA translocation
-
Frank J, Gao H, Sengupta J, Gao N, Taylor DJ (2007) The process of mRNA-tRNA translocation. Proc Natl Acad Sci USA 104:19671-19678.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 19671-19678
-
-
Frank, J.1
Gao, H.2
Sengupta, J.3
Gao, N.4
Taylor, D.J.5
-
5
-
-
0024458904
-
Intermediate states in the movement of transfer RNA in the ribosome
-
DOI 10.1038/342142a0
-
Moazed D, Noller HF (1989) Intermediate states in the movement of transfer RNA in the ribosome. Nature 342:142-148. (Pubitemid 19277015)
-
(1989)
Nature
, vol.342
, Issue.6246
, pp. 142-148
-
-
Moazed, D.1
Noller, H.F.2
-
6
-
-
0034691576
-
A ratchet-like inter-subunit reorganization of the ribosome during translocation
-
DOI 10.1038/35018597
-
Frank J, Agrawal RK (2000) A ratchet-like inter-subunit reorganization of the ribosome during translocation. Nature 406:318-322. (Pubitemid 30604411)
-
(2000)
Nature
, vol.406
, Issue.6793
, pp. 318-322
-
-
Frank, J.1
Agrawal, R.K.2
-
7
-
-
27644491082
-
Structures of the bacterial ribosome at 3.5 A resolution
-
DOI 10.1126/science.1117230
-
Schuwirth BS, et al. (2005) Structures of the bacterial ribosome at 3.5 A resolution. Science 310:827-834. (Pubitemid 41567336)
-
(2005)
Science
, vol.310
, Issue.5749
, pp. 827-834
-
-
Schuwirth, B.S.1
Borovinskaya, M.A.2
Hau, C.W.3
Zhang, W.4
Vila-Sanjurjo, A.5
Holton, J.M.6
Cate, J.H.D.7
-
8
-
-
78649873931
-
Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites
-
Ratje AH, et al. (2010) Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites. Nature 468:713-716.
-
(2010)
Nature
, vol.468
, pp. 713-716
-
-
Ratje, A.H.1
-
9
-
-
34247560812
-
Structures of modified eEF2.80S ribosome complexes reveal the role of GTP hydrolysis in translocation
-
DOI 10.1038/sj.emboj.7601677, PII 7601677
-
Taylor DJ, et al. (2007) Structures of modified eEF2 80S ribosome complexes reveal the role of GTP hydrolysis in translocation. EMBO J 26:2421-2431. (Pubitemid 46685859)
-
(2007)
EMBO Journal
, vol.26
, Issue.9
, pp. 2421-2431
-
-
Taylor, D.J.1
Nilsson, J.2
Merrill, A.R.3
Andersen, G.R.4
Nissen, P.5
Frank, J.6
-
10
-
-
1842576803
-
Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation
-
DOI 10.1038/sj.emboj.7600102
-
Spahn CM, et al. (2004) Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation. EMBO J 23:1008-1019. (Pubitemid 38436866)
-
(2004)
EMBO Journal
, vol.23
, Issue.5
, pp. 1008-1019
-
-
Spahn, C.M.T.1
Gomez-Lorenzo, M.G.2
Grassucci, R.A.3
Jorgensen, R.4
Andersen, G.R.5
Beckmann, R.6
Penczek, P.A.7
Ballesta, J.P.G.8
Frank, J.9
-
11
-
-
55949134736
-
Structure of ratcheted ribosomes with tRNAs in hybrid states
-
Julian P, et al. (2008) Structure of ratcheted ribosomes with tRNAs in hybrid states. Proc Natl Acad Sci USA 105:16924-16927.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 16924-16927
-
-
Julian, P.1
-
12
-
-
4444313551
-
tRNA dynamics on the ribosome during translation
-
DOI 10.1073/pnas.0403884101
-
Blanchard SC, Kim HD, Gonzalez RL, Jr., Puglisi JD, Chu S (2004) tRNA dynamics on the ribosome during translation. Proc Natl Acad Sci USA 101:12893-12898. (Pubitemid 39167554)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.35
, pp. 12893-12898
-
-
Blanchard, S.C.1
Kim, H.D.2
Gonzalez Jr., R.L.3
Puglisi, J.D.4
Chu, S.5
-
13
-
-
42949126723
-
Coupling of Ribosomal L1 Stalk and tRNA Dynamics during Translation Elongation
-
DOI 10.1016/j.molcel.2008.03.012, PII S1097276508002128
-
Fei J, Kosuri P, MacDougall DD, Gonzalez RL, Jr. (2008) Coupling of ribosomal L1 stalk and tRNA dynamics during translation elongation. Mol Cell 30:348-359. (Pubitemid 351615315)
-
(2008)
Molecular Cell
, vol.30
, Issue.3
, pp. 348-359
-
-
Fei, J.1
Kosuri, P.2
MacDougall, D.D.3
Gonzalez Jr., R.L.4
-
14
-
-
44449125068
-
Spontaneous Intersubunit Rotation in Single Ribosomes
-
DOI 10.1016/j.molcel.2008.05.004, PII S1097276508003341
-
Cornish PV, Ermolenko DN, Noller HF, Ha T (2008) Spontaneous intersubunit rotation in single ribosomes. Mol Cell 30:578-588. (Pubitemid 351760964)
-
(2008)
Molecular Cell
, vol.30
, Issue.5
, pp. 578-588
-
-
Cornish, P.V.1
Ermolenko, D.N.2
Noller, H.F.3
Ha, T.4
-
15
-
-
54049116765
-
Visualization of the hybrid state of tRNA binding promoted by spontaneous ratcheting of the ribosome
-
Agirrezabala X, et al. (2008) Visualization of the hybrid state of tRNA binding promoted by spontaneous ratcheting of the ribosome. Mol Cell 32:190-197.
-
(2008)
Mol Cell
, vol.32
, pp. 190-197
-
-
Agirrezabala, X.1
-
16
-
-
34250220008
-
Observation of Intersubunit Movement of the Ribosome in Solution Using FRET
-
DOI 10.1016/j.jmb.2007.04.042, PII S0022283607005190
-
Ermolenko DN, et al. (2007) Observation of intersubunit movement of the ribosome in solution using FRET. J Mol Biol 370:530-540. (Pubitemid 46898430)
-
(2007)
Journal of Molecular Biology
, vol.370
, Issue.3
, pp. 530-540
-
-
Ermolenko, D.N.1
Majumdar, Z.K.2
Hickerson, R.P.3
Spiegel, P.C.4
Clegg, R.M.5
Noller, H.F.6
-
17
-
-
67651178174
-
The ribosome as a conveying thermal ratchet machine
-
Spirin AS (2009) The ribosome as a conveying thermal ratchet machine. J Biol Chem 284:21103-21119.
-
(2009)
J Biol Chem
, vol.284
, pp. 21103-21119
-
-
Spirin, A.S.1
-
19
-
-
77953625418
-
Structure and dynamics of a processive Brownian motor: The translating ribosome
-
Frank J, Gonzalez RL, Jr. (2010) Structure and dynamics of a processive Brownian motor: The translating ribosome. Annu Rev Biochem 79:381-412.
-
(2010)
Annu Rev Biochem
, vol.79
, pp. 381-412
-
-
Frank, J.1
Gonzalez Jr., R.L.2
-
20
-
-
33847024820
-
Kinetically Competent Intermediates in the Translocation Step of Protein Synthesis
-
DOI 10.1016/j.molcel.2007.01.014, PII S1097276507000366
-
Pan D, Kirillov SV, Cooperman BS (2007) Kinetically competent intermediates in the translocation step of protein synthesis. Mol Cell 25:519-529. (Pubitemid 46274443)
-
(2007)
Molecular Cell
, vol.25
, Issue.4
, pp. 519-529
-
-
Pan, D.1
Kirillov, S.V.2
Cooperman, B.S.3
-
21
-
-
70349470607
-
Allosteric collaboration between elongation factor G and the ribosomal L1 stalk directs tRNA movements during translation
-
Fei J, et al. (2009) Allosteric collaboration between elongation factor G and the ribosomal L1 stalk directs tRNA movements during translation. Proc Natl Acad Sci USA 106:15702-15707.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 15702-15707
-
-
Fei, J.1
-
22
-
-
62449216538
-
Following movement of the L1 stalk between three functional states in single ribosomes
-
Cornish PV, et al. (2009) Following movement of the L1 stalk between three functional states in single ribosomes. Proc Natl Acad Sci USA 106:2571-2576.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 2571-2576
-
-
Cornish, P.V.1
-
23
-
-
77149151868
-
A fast dynamic mode of the EF-G-bound ribosome
-
Munro JB, Altman RB, Tung CS, Sanbonmatsu KY, Blanchard SC (2010) A fast dynamic mode of the EF-G-bound ribosome. EMBO J 29:770-781.
-
(2010)
EMBO J
, vol.29
, pp. 770-781
-
-
Munro, J.B.1
Altman, R.B.2
Tung, C.S.3
Sanbonmatsu, K.Y.4
Blanchard, S.C.5
-
24
-
-
78649830457
-
Correlated conformational events in EF-G and the ribosome regulate translocation
-
Munro JB, Wasserman MR, Altman RB, Wang L, Blanchard SC (2010) Correlated conformational events in EF-G and the ribosome regulate translocation. Nat Struct Mol Biol 17:1470-1477.
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 1470-1477
-
-
Munro, J.B.1
Wasserman, M.R.2
Altman, R.B.3
Wang, L.4
Blanchard, S.C.5
-
25
-
-
79953777970
-
MRNA translocation occurs during the second step of ribosomal intersubunit rotation
-
Ermolenko DN, Noller HF (2011) mRNA translocation occurs during the second step of ribosomal intersubunit rotation. Nat Struct Mol Biol 18:457-462.
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 457-462
-
-
Ermolenko, D.N.1
Noller, H.F.2
-
26
-
-
79955494464
-
Single-molecule fluorescence measurements of ribosomal translocation dynamics
-
Chen C, et al. (2011) Single-molecule fluorescence measurements of ribosomal translocation dynamics. Mol Cell 42:367-377.
-
(2011)
Mol Cell
, vol.42
, pp. 367-377
-
-
Chen, C.1
-
27
-
-
34249887127
-
The antibiotic viomycin traps the ribosome in an intermediate state of translocation
-
DOI 10.1038/nsmb1243, PII NSMB1243
-
Ermolenko DN, et al. (2007) The antibiotic viomycin traps the ribosome in an intermediate state of translocation. Nat Struct Mol Biol 14:493-497. (Pubitemid 46871807)
-
(2007)
Nature Structural and Molecular Biology
, vol.14
, Issue.6
, pp. 493-497
-
-
Ermolenko, D.N.1
Spiegel, P.C.2
Majumdar, Z.K.3
Hickerson, R.P.4
Clegg, R.M.5
Noller, H.F.6
-
28
-
-
33847051154
-
Identification of Two Distinct Hybrid State Intermediates on the Ribosome
-
DOI 10.1016/j.molcel.2007.01.022, PII S1097276507000457
-
Munro JB, Altman RB, O'Connor N, Blanchard SC (2007) Identification of two distinct hybrid state intermediates on the ribosome. Mol Cell 25:505-517. (Pubitemid 46274447)
-
(2007)
Molecular Cell
, vol.25
, Issue.4
, pp. 505-517
-
-
Munro, J.B.1
Altman, R.B.2
O'Connor, N.3
Blanchard, S.C.4
-
29
-
-
77954650144
-
Ribosome dynamics and tRNA movement by time-resolved electron cryomicroscopy
-
Fischer N, Konevega AL, Wintermeyer W, Rodnina MV, Stark H (2010) Ribosome dynamics and tRNA movement by time-resolved electron cryomicroscopy. Nature 466:329-333.
-
(2010)
Nature
, vol.466
, pp. 329-333
-
-
Fischer, N.1
Konevega, A.L.2
Wintermeyer, W.3
Rodnina, M.V.4
Stark, H.5
-
30
-
-
79953216748
-
Cryoelectron microscopy structures of the ribosome complex in intermediate states during tRNA translocation
-
Fu J, Munro JB, Blanchard SC, Frank J (2011) Cryoelectron microscopy structures of the ribosome complex in intermediate states during tRNA translocation. Proc Natl Acad Sci USA 108:4817-4821.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 4817-4821
-
-
Fu, J.1
Munro, J.B.2
Blanchard, S.C.3
Frank, J.4
-
31
-
-
69249112231
-
Structures of the ribosome in intermediate states of ratcheting
-
Zhang W, Dunkle JA, Cate JH (2009) Structures of the ribosome in intermediate states of ratcheting. Science 325:1014-1017.
-
(2009)
Science
, vol.325
, pp. 1014-1017
-
-
Zhang, W.1
Dunkle, J.A.2
Cate, J.H.3
-
32
-
-
33845939047
-
Disentangling conformational states of macromolecules in 3D-EM through likelihood optimization
-
DOI 10.1038/nmeth992, PII NMETH992
-
Scheres SH, et al. (2007) Disentangling conformational states of macromolecules in 3DEM through likelihood optimization. Nat Methods 4:27-29. (Pubitemid 46029470)
-
(2007)
Nature Methods
, vol.4
, Issue.1
, pp. 27-29
-
-
Scheres, S.H.W.1
Gao, H.2
Valle, M.3
Herman, G.T.4
Eggermont, P.P.B.5
Frank, J.6
Carazo, J.-M.7
-
33
-
-
79955020725
-
Structural insights into cognate versus near-cognate discrimination during decoding
-
Agirrezabala X, et al. (2011) Structural insights into cognate versus near-cognate discrimination during decoding. EMBO J 30:1497-1507.
-
(2011)
EMBO J
, vol.30
, pp. 1497-1507
-
-
Agirrezabala, X.1
-
34
-
-
42949089487
-
Flexible Fitting of Atomic Structures into Electron Microscopy Maps Using Molecular Dynamics
-
DOI 10.1016/j.str.2008.03.005, PII S0969212608001330
-
Trabuco LG, Villa E, Mitra K, Frank J, Schulten K (2008) Flexible fitting of atomic structures into electron microscopy maps using molecular dynamics. Structure 16:673-683. (Pubitemid 351615021)
-
(2008)
Structure
, vol.16
, Issue.5
, pp. 673-683
-
-
Trabuco, L.G.1
Villa, E.2
Mitra, K.3
Frank, J.4
Schulten, K.5
-
35
-
-
79956303529
-
Structures of the bacterial ribosome in classical and hybrid states of tRNA binding
-
Dunkle JA, et al. (2011) Structures of the bacterial ribosome in classical and hybrid states of tRNA binding. Science 332:981-984.
-
(2011)
Science
, vol.332
, pp. 981-984
-
-
Dunkle, J.A.1
-
36
-
-
80053155455
-
Crystal structure of the hybrid state of ribosome in complex with the guanosine triphosphatase release factor 3
-
Jin H, Kelley AC, Ramakrishnan V (2011) Crystal structure of the hybrid state of ribosome in complex with the guanosine triphosphatase release factor 3. Proc Natl Acad Sci USA 108:15798-15803.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 15798-15803
-
-
Jin, H.1
Kelley, A.C.2
Ramakrishnan, V.3
-
37
-
-
70350602056
-
The structure of the ribosome with elongation factor G trapped in the posttranslocational state
-
Gao YG, et al. (2009) The structure of the ribosome with elongation factor G trapped in the posttranslocational state. Science 326:694-699.
-
(2009)
Science
, vol.326
, pp. 694-699
-
-
Gao, Y.G.1
-
38
-
-
33750488430
-
Structural basis for mRNA and tRNA positioning on the ribosome
-
DOI 10.1073/pnas.0607541103
-
Berk V, Zhang W, Pai RD, Cate JH (2006) Structural basis for mRNA and tRNA positioning on the ribosome. Proc Natl Acad Sci USA 103:15830-15834. (Pubitemid 44657552)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.43
, pp. 15830-15834
-
-
Berk, V.1
Zhang, W.2
Pai, R.D.3
Cate, J.H.D.4
-
39
-
-
0042424707
-
Dynamic reorganization of the functionally active ribosome explored by normal mode analysis and cryo-electron microscopy
-
DOI 10.1073/pnas.1632476100
-
Tama F, Valle M, Frank J, Brooks CL, 3rd (2003) Dynamic reorganization of the functionally active ribosome explored by normal mode analysis and cryo-electron microscopy. Proc Natl Acad Sci USA 100:9319-9323. (Pubitemid 37033926)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.16
, pp. 9319-9323
-
-
Tama, F.1
Valle, M.2
Frankt, J.3
Brooks III, C.L.4
-
40
-
-
36549020733
-
Fluctuations of transfer RNAs between classical and hybrid states
-
DOI 10.1529/biophysj.107.109884
-
Kim HD, Puglisi JD, Chu S (2007) Fluctuations of transfer RNAs between classical and hybrid states. Biophys J 93:3575-3582. (Pubitemid 350190820)
-
(2007)
Biophysical Journal
, vol.93
, Issue.10
, pp. 3575-3582
-
-
Kim, H.D.1
Puglisi, J.D.2
Chu, S.3
-
41
-
-
76249114762
-
Spontaneous formation of the unlocked state of the ribosome is a multistep process
-
Munro JB, et al. (2010) Spontaneous formation of the unlocked state of the ribosome is a multistep process. Proc Natl Acad Sci USA 107:709-714.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 709-714
-
-
Munro, J.B.1
-
42
-
-
81755173676
-
Structure and dynamics of the Mammalian ribosomal pretranslocation complex
-
Budkevich T, et al. (2011) Structure and dynamics of the Mammalian ribosomal pretranslocation complex. Mol Cell 44:214-224.
-
(2011)
Mol Cell
, vol.44
, pp. 214-224
-
-
Budkevich, T.1
|