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Volumn 28, Issue 3, 2012, Pages 191-201

Effects of hyperthermia on Hsp27 (HSPB1), Hsp72 (HSPA1A) and DNA repair proteins hMLH1 and hMSH2 in human colorectal cancer hMLH1-deficient and hMLH1-proficient cell lines

Author keywords

comet assay; heat shock proteins; mild hyperthermia; mismatch repair

Indexed keywords

HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 72; PROTEIN MLH1; PROTEIN MSH2;

EID: 84859944588     PISSN: 02656736     EISSN: 14645157     Source Type: Journal    
DOI: 10.3109/02656736.2011.638962     Document Type: Article
Times cited : (21)

References (52)
  • 1
    • 76749158379 scopus 로고    scopus 로고
    • Today's thermal therapy: Not your father's hyperthermia: Challenges and opportunities in application of hyperthermia for the 21st century cancer patient
    • Hurwitz MD. Today's thermal therapy: Not your father' hyperthermia: Challenges and opportunities in application of hyperthermia for the 21st century cancer patient. Am J Clin Oncol 2011;33:96-100.
    • (2011) Am. J. Clin. Oncol. , vol.33 , pp. 96-100
    • Hurwitz, M.D.1
  • 2
    • 65749098039 scopus 로고    scopus 로고
    • Heat-responsive gene expression for gene therapy
    • Walther W, Stein U. Heat-responsive gene expression for gene therapy. Adv Drug Deliv Rev 2009;61:641-649.
    • (2009) Adv. Drug. Deliv. Rev. , vol.61 , pp. 641-649
    • Walther, W.1    Stein, U.2
  • 4
    • 21744445069 scopus 로고    scopus 로고
    • Heat shock proteins in cancer: Diagnostic, prognostic, predictive and treatment implications
    • Ciocca DR, Calderwood SK. Heat shock proteins in cancer: Diagnostic, prognostic, predictive and treatment implications. Cell Stress Chaperones 2005;10:86-103.
    • (2005) Cell Stress Chaperones , vol.10 , pp. 86-103
    • Ciocca, D.R.1    Calderwood, S.K.2
  • 5
    • 34250726554 scopus 로고    scopus 로고
    • Heat-induced alterations of nuclear protein associations and their effects on DNA repair and replication
    • Roti Roti, JL. Heat-induced alterations of nuclear protein associations and their effects on DNA repair and replication. Int J Hyperthermia 2007;23:3-15.
    • (2007) Int. J. Hyperthermia , vol.23 , pp. 3-15
    • Roti Roti, J.L.1
  • 6
    • 1842472960 scopus 로고    scopus 로고
    • Heat induced 'masking' of redox sensitive component(s) of the DNA-nuclear matrix anchoring complex
    • Vanderwaal RP, Roti Roti JL. Heat induced 'masking' of redox sensitive component(s) of the DNA-nuclear matrix anchoring complex. Int J Hyperthermia 2004;20:234-239.
    • (2004) Int. J. Hyperthermia , vol.20 , pp. 234-239
    • Vanderwaal, R.P.1    Roti Roti, J.L.2
  • 7
    • 38649088879 scopus 로고    scopus 로고
    • Cellular responses to hyperthermia (40-46-C): Cell killing and molecular events
    • Roti Roti, JL. Cellular responses to hyperthermia (40-46-C): Cell killing and molecular events. Int J Hypertthermia 2008;24:3-15.
    • (2008) Int. J. Hypertthermia , vol.24 , pp. 3-15
    • Roti Roti, J.L.1
  • 8
    • 10844286478 scopus 로고    scopus 로고
    • Evidence for the involvement of double-strand breaks in heat-induced cell killing
    • Takahashi A, Matsumoto H, Nagayama K, Kitano M, Hirose S, Tanaka H, et al. Evidence for the involvement of double-strand breaks in heat-induced cell killing. Cancer Res 2004;64:8839-8845.
    • (2004) Cancer Res. , vol.64 , pp. 8839-8845
    • Takahashi, A.1    Matsumoto, H.2    Nagayama, K.3    Kitano, M.4    Hirose, S.5    Tanaka, H.6
  • 9
    • 43649100745 scopus 로고    scopus 로고
    • Development of thermotolerance requires interaction between polymerase-beta and heat shock proteins
    • Takahashi A, Yamakawa N, Mori E, Ohnishi K, Yokota S, Sugo N, et al. Development of thermotolerance requires interaction between polymerase-beta and heat shock proteins. Cancer Sci 2008;99:973-978.
    • (2008) Cancer Sci. , vol.99 , pp. 973-978
    • Takahashi, A.1    Yamakawa, N.2    Mori, E.3    Ohnishi, K.4    Yokota, S.5    Sugo, N.6
  • 10
    • 84891980597 scopus 로고    scopus 로고
    • Participation of heat shock proteins in DNA repair mechanisms in cancer
    • Columbus F editor. DNA Repair: Damage Repair Mechanisms and Aging New York Publishers
    • Nadin SB, Ciocca DR. Participation of heat shock proteins in DNA repair mechanisms in cancer. In: Columbus F, editor. DNA Repair: Damage, Repair Mechanisms and Aging. New York: Nova Science Publishers; 2010. pp 165-186.
    • (2010) Nova Science , pp. 165-186
    • Nadin, S.B.1    Ciocca, D.R.2
  • 11
    • 70350001064 scopus 로고    scopus 로고
    • Hsp70 translocates to the nuclei and nucleoli, binds to XRCC1 and PARP-1, and protects HeLa cells from single-strand DNA breaks
    • Kotoglou P, Kalitzakis A, Vezyraki P, Tzavaras T, Michalis LK, Dantzar F, et al. Hsp70 translocates to the nuclei and nucleoli, binds to XRCC1 and PARP-1, and protects HeLa cells from single-strand DNA breaks. Cell Stress Chaperones 2009;14:391-406.
    • (2009) Cell Stress Chaperones , vol.14 , pp. 391-406
    • Kotoglou, P.1    Kalitzakis, A.2    Vezyraki, P.3    Tzavaras, T.4    Michalis, L.K.5    Dantzar, F.6
  • 12
    • 0347356337 scopus 로고    scopus 로고
    • Genomic instability and enhanced radiosensitivity in Hsp70.1- and Hsp70.3-deficient mice
    • Hunt CR, Dix DJ, Sharma GG, Pandita RK, Gupta A, Funk M, et al. Genomic instability and enhanced radiosensitivity in Hsp70.1- and Hsp70.3-deficient mice. Mol Cell Biol 2004;24:899-911.
    • (2004) Mol. Cell Biol. , vol.24 , pp. 899-911
    • Hunt, C.R.1    Dix, D.J.2    Sharma, G.G.3    Pandita, R.K.4    Gupta, A.5    Funk, M.6
  • 13
    • 0037445248 scopus 로고    scopus 로고
    • Role of DNA mismatch repair defects in the pathogenesis of human cancer
    • Peltomaki P. Role of DNA mismatch repair defects in the pathogenesis of human cancer. J Clin Oncol 2003; 21:1174-1179.
    • (2003) J. Clin. Oncol. , vol.21 , pp. 1174-1179
    • Peltomaki, P.1
  • 14
    • 0034597548 scopus 로고    scopus 로고
    • Mismatch repair: The praying hands of fidelity
    • Jiricny J. Mismatch repair: The praying hands of fidelity. Curr Biol 2000;10:788-790.
    • (2000) Curr. Biol. , vol.10 , pp. 788-790
    • Jiricny, J.1
  • 15
    • 0035902108 scopus 로고    scopus 로고
    • Genomic maintenance mechanisms for preventing cancer
    • Hoeijmakers JHJ. Genomic maintenance mechanisms for preventing cancer. Nature 2001;411:366-374.
    • (2001) Nature , vol.411 , pp. 366-374
    • Hoeijmakers, J.H.J.1
  • 16
    • 38049125557 scopus 로고    scopus 로고
    • Mechanisms and functions of DNA mismatch repair
    • Li G-M. Mechanisms and functions of DNA mismatch repair. Cell Res 2008;18:85-98.
    • (2008) Cell Res. , vol.18 , pp. 85-98
    • Li, G.-M.1
  • 17
    • 34248400771 scopus 로고    scopus 로고
    • Hsp27, Hsp70 and mismatch repair proteins hMLH1 and hMSH2 expression in peripheral blood lymphocytes from healthy subjects and cancer patients
    • Nadin SB, Vargas-Roig LM, Drago G, Ibarra J, Ciocca DR. Hsp27, Hsp70 and mismatch repair proteins hMLH1 and hMSH2 expression in peripheral blood lymphocytes from healthy subjects and cancer patients. Cancer Lett 2007; 252:131-146.
    • (2007) Cancer Lett. , vol.252 , pp. 131-146
    • Nadin, S.B.1    Vargas-Roig, L.M.2    Drago, G.3    Ibarra, J.4    Ciocca, D.R.5
  • 18
    • 0028221943 scopus 로고
    • Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary nonpolyposis colon cancer
    • Bronner CE, Baker SM, Morrison PT, Warren G, Smith LG, Lescoe MK, et al. Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary nonpolyposis colon cancer. Nature 1994;368:258-261.
    • (1994) Nature , vol.368 , pp. 258-261
    • Bronner, C.E.1    Baker, S.M.2    Morrison, P.T.3    Warren, G.4    Smith, L.G.5    Lescoe, M.K.6
  • 19
    • 0028784167 scopus 로고
    • Microsatellite instability, mismatch repair deficiency, and genetic defects in human cancer cell lines
    • Boyer JC, Umar A, Risinger JI, Lipford JR, Kane M, Yin S, et al. Microsatellite instability, mismatch repair deficiency, and genetic defects in human cancer cell lines. Cancer Res 1995;55:6063-6070.
    • (1995) Cancer Res. , vol.55 , pp. 6063-6070
    • Boyer, J.C.1    Umar, A.2    Risinger, J.I.3    Lipford, J.R.4    Kane, M.5    Yin, S.6
  • 20
    • 0027936057 scopus 로고
    • Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N'-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation
    • Koi M, Umar A, Chauhan DP, Cherian SP, Carethers JM, Kunkel TA, et al. Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N'-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation. Cancer Res 1994;54:4308-4312.
    • (1994) Cancer Res. , vol.54 , pp. 4308-4312
    • Koi, M.1    Umar, A.2    Chauhan, D.P.3    Cherian, S.P.4    Carethers, J.M.5    Kunkel, T.A.6
  • 21
    • 0025730640 scopus 로고
    • A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells
    • Andrews NC, Faller DV. A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucleic Acids Res 1991;19:2499.
    • (1991) Nucleic. Acids. Res. , vol.19 , pp. 2499
    • Andrews, N.C.1    Faller, D.V.2
  • 22
    • 0026592534 scopus 로고
    • Factors influencing DNA migration from individual cells subjected to gel electrophoresis
    • Olive PL, Wlodek D, Durand RE, Banath JP. Factors influencing DNA migration from individual cells subjected to gel electrophoresis. Exp Cell Res 1992;198:259-267.
    • (1992) Exp. Cell Res. , vol.198 , pp. 259-267
    • Olive, P.L.1    Wlodek, D.2    Durand, R.E.3    Banath, J.P.4
  • 24
    • 0028305534 scopus 로고
    • The effect of various antioxidants and other modifying agents on oxygenradical- generated DNA damage in human lymphocytes in the COMET assay
    • Anderson D, Yu T-W, Phillips BJ, Shemezer P. The effect of various antioxidants and other modifying agents on oxygenradical- generated DNA damage in human lymphocytes in the COMET assay. Mutat Res 1994;307:261-271.
    • (1994) Mutat. Res. , vol.307 , pp. 261-271
    • Anderson, D.1    Yu, T.-W.2    Phillips, B.J.3    Shemezer, P.4
  • 25
    • 11344286813 scopus 로고    scopus 로고
    • DNA damage induced by paclitaxel and DNA repair capability of peripheral blood lymphocytes as evaluated by the alkaline comet assay
    • Branham MT, Nadin SB, Vargas-Roig LM, Ciocca DR. DNA damage induced by paclitaxel and DNA repair capability of peripheral blood lymphocytes as evaluated by the alkaline comet assay. Mutat Res 2004;560:11-17.
    • (2004) Mutat. Res. , vol.560 , pp. 11-17
    • Branham, M.T.1    Nadin, S.B.2    Vargas-Roig, L.M.3    Ciocca, D.R.4
  • 26
    • 0035169329 scopus 로고    scopus 로고
    • Rapid screening assay for mutagen sensitivity and DNA repair capacity in human peripheral blood lymphocytes
    • Schemezer P, Rajaee-Behbahani N, Risch A, Thiel S, Rittgen W, Drings P, et al. Rapid screening assay for mutagen sensitivity and DNA repair capacity in human peripheral blood lymphocytes. Mutagenesis 2001;16:25-30.
    • (2001) Mutagenesis , vol.16 , pp. 25-30
    • Schemezer, P.1    Rajaee-Behbahani, N.2    Risch, A.3    Thiel, S.4    Rittgen, W.5    Drings, P.6
  • 27
    • 33947267567 scopus 로고    scopus 로고
    • High levels of heat shock protein Hsp72 in cancer cells suppress default senescence pathways
    • Yaglom JA, Gabai VL, Sherman MY. High levels of heat shock protein Hsp72 in cancer cells suppress default senescence pathways. Cancer Res 2007;67:2373-2381.
    • (2007) Cancer Res. , vol.67 , pp. 2373-2381
    • Yaglom, J.A.1    Gabai, V.L.2    Sherman, M.Y.3
  • 28
    • 0035827709 scopus 로고    scopus 로고
    • Starvation promotes nuclear accumulation of the Hsp70 Ssa4p in yeast cells
    • Chughtai ZS, Rassadi R, Matusiewicz N, Stochaj U. Starvation promotes nuclear accumulation of the Hsp70 Ssa4p in yeast cells. J Biol Chem 2001;276:20261-20266.
    • (2001) J. Biol. Chem. , vol.276 , pp. 20261-20266
    • Chughtai, Z.S.1    Rassadi, R.2    Matusiewicz, N.3    Stochaj, U.4
  • 30
    • 0028832880 scopus 로고
    • Reversible nucleolar translocation of Epstein-Barr virus-encoded EBNA-5 and Hsp70 proteins after exposure to heat shock or cell density congestion
    • Szekely L, Jiang WQ, Pokrovskaja K, Wiman KG, Klein G, Ringertz N. Reversible nucleolar translocation of Epstein-Barr virus-encoded EBNA-5 and Hsp70 proteins after exposure to heat shock or cell density congestion. J Gen Virol 1995;76:2423-2432.
    • (1995) J. Gen. Virol. , vol.76 , pp. 2423-2432
    • Szekely, L.1    Jiang, W.Q.2    Pokrovskaja, K.3    Wiman, K.G.4    Klein, G.5    Ringertz, N.6
  • 31
    • 0242330183 scopus 로고    scopus 로고
    • Overexpression of Hsp70 is induced by ionizing radiation in C3H 10T1/2 cells and protects from DNA damage
    • Calini V, Urani C, Camatini M. Overexpression of Hsp70 is induced by ionizing radiation in C3H 10T1/2 cells and protects from DNA damage. Toxicol In Vitro 2003;17:561-566.
    • (2003) Toxicol In. Vitro. , vol.17 , pp. 561-566
    • Calini, V.1    Urani, C.2    Camatini, M.3
  • 32
    • 33745330907 scopus 로고    scopus 로고
    • Overexpressed heat shock protein 70 protects cells against DNA damage caused by ultraviolet C in a dose-dependent manner
    • Niu P, Liu L, Gong Z, Tan H, Wang F, Yuan J, et al. Overexpressed heat shock protein 70 protects cells against DNA damage caused by ultraviolet C in a dose-dependent manner. Cell Stress Chaperones 2006;11:162-169.
    • (2006) Cell Stress Chaperones , vol.11 , pp. 162-169
    • Niu, P.1    Liu, L.2    Gong, Z.3    Tan, H.4    Wang, F.5    Yuan, J.6
  • 33
    • 0042527130 scopus 로고    scopus 로고
    • Heat shock protein 70 stimulation of the deoxyribonucleic acid base excision repair enzyme polymerase beta
    • Mendez F, Kozin E, Bases R. Heat shock protein 70 stimulation of the deoxyribonucleic acid base excision repair enzyme polymerase beta. Cell Stress Chaperones 2003;8:153-161.
    • (2003) Cell Stress Chaperones , vol.8 , pp. 153-161
    • Mendez, F.1    Kozin, E.2    Bases, R.3
  • 34
    • 0034951854 scopus 로고    scopus 로고
    • Translocation of MRE11 from the nucleus to the cytoplasm as a mechanism of radiosensitization by heat
    • Zhu WG, Seno JD, Beck BD, Dynlacht JR. Translocation of MRE11 from the nucleus to the cytoplasm as a mechanism of radiosensitization by heat. Radiat Res 2001;156:95-102.
    • (2001) Radiat. Res. , vol.156 , pp. 95-102
    • Zhu, W.G.1    Seno, J.D.2    Beck, B.D.3    Dynlacht, J.R.4
  • 35
    • 34250678489 scopus 로고    scopus 로고
    • The effects of 41 C hyperthermia on the DNA repair protein, MRE11, correlate with radiosensitization in four human tumour cell lines
    • Xu M, Myerson RJ, Xia Y, Whitehead T, Moros EG, Straube WL, et al. The effects of 41 C hyperthermia on the DNA repair protein, MRE11, correlate with radiosensitization in four human tumour cell lines. Int J Hyperthermia 2007;23:343-351.
    • (2007) Int. J. Hyperthermia , vol.23 , pp. 343-351
    • Xu, M.1    Myerson, R.J.2    Xia, Y.3    Whitehead, T.4    Moros, E.G.5    Straube, W.L.6
  • 36
  • 37
    • 79953186673 scopus 로고    scopus 로고
    • Hmsh2 recruits ATR to DNA damage sites for activation during DNA damage-induced apoptosis
    • Pabla N, Ma Z, McIlhatton MA, Fishel R, Dong Z. hMSH2 recruits ATR to DNA damage sites for activation during DNA damage-induced apoptosis. J Biol Chem 2011;286: 10411-10418.
    • (2011) J. Biol. Chem. , vol.286 , pp. 10411-10418
    • Pabla, N.1    Ma, Z.2    McIlhatton, M.A.3    Fishel, R.4    Dong, Z.5
  • 38
    • 78650031418 scopus 로고    scopus 로고
    • A CRM1-dependent nuclear export pathway is involved in the regulation of MutL- subcellular localization
    • Brieger A, Adam R, Passmann S, Plotz G, Zeuzem S, Trojan J. A CRM1-dependent nuclear export pathway is involved in the regulation of MutL subcellular localization. Genes Chromosomes Cancer 2011;50:59-70.
    • (2011) Genes. Chromosomes Cancer , vol.50 , pp. 59-70
    • Brieger, A.1    Adam, R.2    Passmann, S.3    Plotz, G.4    Zeuzem, S.5    Trojan, J.6
  • 39
    • 75149143337 scopus 로고    scopus 로고
    • Nuclear reorganization of DNA mismatch repair proteins in response to DNA damage
    • Mastrocola AS, Heinen CD. Nuclear reorganization of DNA mismatch repair proteins in response to DNA damage. DNA Repair (Amst) 2010;9:120-133.
    • (2010) DNA Repair. (Amst) , vol.9 , pp. 120-133
    • Mastrocola, A.S.1    Heinen, C.D.2
  • 40
    • 0026607443 scopus 로고
    • The effects of hyperthermia on mammalian cell structure and function
    • Laszlo A. The effects of hyperthermia on mammalian cell structure and function. Cell Prolif 1992;25:59-87.
    • (1992) Cell Prolif. , vol.25 , pp. 59-87
    • Laszlo, A.1
  • 41
    • 1842577655 scopus 로고    scopus 로고
    • Mechanism of radiosensitization by hyperthermia (4or -43 C) as derived from studies with DNA repair defective mutant cell lines
    • Kampinga HH, Dynlacht JR, Dikomey E. Mechanism of radiosensitization by hyperthermia (4or -43 C) as derived from studies with DNA repair defective mutant cell lines. Int J Hyperthermia 2004;20:131-139.
    • (2004) Int. J. Hyperthermia , vol.20 , pp. 131-139
    • Kampinga, H.H.1    Dynlacht, J.R.2    Dikomey, E.3
  • 42
    • 0037085734 scopus 로고    scopus 로고
    • Heat-induced formation of reactive oxygen species and 8-oxoguanine, a biomarker of damage to DNA
    • Bruskov VI, Malakhova LV, Masalimov ZK, Chernikov AV. Heat-induced formation of reactive oxygen species and 8-oxoguanine, a biomarker of damage to DNA. Nucleic Acids Res 2002;30:1354-1363.
    • (2002) Nucleic. Acids. Res. , vol.30 , pp. 1354-1363
    • Bruskov, V.I.1    Malakhova, L.V.2    Masalimov, Z.K.3    Chernikov, A.V.4
  • 43
    • 0023612931 scopus 로고
    • Apurinic site induction in the DNA of cells heated at hyperthermic temperatures
    • Warters RL, Brizgys LM. Apurinic site induction in the DNA of cells heated at hyperthermic temperatures. J Cell Physiol 1987;133:144-150.
    • (1987) J. Cell Physiol. , vol.133 , pp. 144-150
    • Warters, R.L.1    Brizgys, L.M.2
  • 44
    • 0016257644 scopus 로고
    • Heat-induced deamination of cytosine residues in deoxyribonucleic acid
    • Lindahl T, Nyberg B. Heat-induced deamination of cytosine residues in deoxyribonucleic acid. Biochemistry 1974;13: 3405-3410.
    • (1974) Biochemistry. , vol.13 , pp. 3405-3410
    • Lindahl, T.1    Nyberg, B.2
  • 45
    • 0028067242 scopus 로고
    • Hyperthermia stimulates nitric oxide formation: Electron paramagnetic resonance detection of NO-heme in blood
    • Hall DM, Buettner GR, Matthes RD, Gisolfi CV. Hyperthermia stimulates nitric oxide formation: Electron paramagnetic resonance detection of NO-heme in blood. J Appl Physiol 1994;77:548-553.
    • (1994) J. Appl. Physiol. , vol.77 , pp. 548-553
    • Hall, D.M.1    Buettner, G.R.2    Matthes, R.D.3    Gisolfi, C.V.4
  • 47
    • 0035866361 scopus 로고    scopus 로고
    • P53 modulates the effect of loss of DNA mismatch repair on the sensitivity of human colon cancer cells to the cytotoxic and mutagenic effects of cisplatin
    • Lin X, Ramamurthi K, Mishima M, Kondo A, Christen RD, Howell SB. p53 modulates the effect of loss of DNA mismatch repair on the sensitivity of human colon cancer cells to the cytotoxic and mutagenic effects of cisplatin. Cancer Res 2001;61:1508-1516.
    • (2001) Cancer Res. , vol.61 , pp. 1508-1516
    • Lin, X.1    Ramamurthi, K.2    Mishima, M.3    Kondo, A.4    Christen, R.D.5    Howell, S.B.6
  • 48
    • 34248158282 scopus 로고    scopus 로고
    • Hyperthermia activates a subset of ataxiatelangiectasia mutated effectors independent of DNA strand breaks and heat shock protein 70 status
    • Hunt CR, Pandita RK, Laszlo A, Higashikubo R, Agarwal M, Kitamura T, et al. Hyperthermia activates a subset of ataxiatelangiectasia mutated effectors independent of DNA strand breaks and heat shock protein 70 status. Cancer Res 2007;67:3010-3017.
    • (2007) Cancer Res. , vol.67 , pp. 3010-3017
    • Hunt, C.R.1    Pandita, R.K.2    Laszlo, A.3    Higashikubo, R.4    Agarwal, M.5    Kitamura, T.6
  • 49
    • 28544446812 scopus 로고    scopus 로고
    • DNA double strand breaks do not play a role in heat-induced cell killing
    • Kampinga HH, Laszlo A. DNA double strand breaks do not play a role in heat-induced cell killing. Cancer Res 2005;65:10632-10633.
    • (2005) Cancer Res. , vol.65 , pp. 10632-10633
    • Kampinga, H.H.1    Laszlo, A.2
  • 50
    • 67949100595 scopus 로고    scopus 로고
    • The heat-induced gamma-H2AX response does not play a role in hyperthermic cell killing
    • Laszlo A, Fleischer I. The heat-induced gamma-H2AX response does not play a role in hyperthermic cell killing. Int J Hyperthermia 2009;25:199-209.
    • (2009) Int. J. Hyperthermia , vol.25 , pp. 199-209
    • Laszlo, A.1    Fleischer, I.2
  • 51
    • 69249127842 scopus 로고    scopus 로고
    • Nucleophosmin redistribution following heat shock: A role in heat-induced radiosensitization
    • Vanderwaal RP, Maggi Jr LB, Weber JD, Hunt CR, Roti Roti JL. Nucleophosmin redistribution following heat shock: A role in heat-induced radiosensitization. Cancer Res 2009;69:6454-6462.
    • (2009) Cancer Res. , vol.69 , pp. 6454-6462
    • Vanderwaal, R.P.1    Maggi, Jr.L.B.2    Weber, J.D.3    Hunt, C.R.4    Roti Roti, J.L.5


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