Activation of target signal transducers utilizing chimeric receptors with signaling-molecule binding motifs

Biotechnology and Bioengineering

Volumn 109, Issue 6, 2012, Pages 1528-1537

  Saka, Koichiro ^a   Kawahara, Masahiro ^a   Ueda, Hiroshi ^a   Nagamune, Teruyuki ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Antibody; Chimeric protein; Receptor; Signal transduction; Tyrosine motif

Indexed keywords

ACTIVATION LEVEL; ANTI-FLUORESCEIN; ARTIFICIAL RECEPTORS; BINDING DOMAIN; BINDING MOTIF; CELL LINES; CHIMERIC PROTEINS; CHIMERIC RECEPTORS; CYTOKINE RECEPTOR; CYTOPLASMIC DOMAINS; INTRACELLULAR DOMAIN; JANUS KINASE; RECEPTOR; RETROVIRAL TRANSDUCTION; SIGNAL TRANSDUCERS; SIGNALING CASCADES; SIGNALING MOLECULES; TARGET MOLECULE; TARGET SIGNALS; TYROSINE MOTIF;

AMINO ACIDS; ANTIBODIES; CELL CULTURE; MOLECULES; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSDUCERS;

SIGNALING;

CYTOKINE RECEPTOR; INTERLEUKIN 3; JANUS KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN SHC; STAT1 PROTEIN; STAT3 PROTEIN; STAT5 PROTEIN; TYROSINE;

ANIMAL CELL; ARTICLE; CELL LINE; CONTROLLED STUDY; CYTOPLASM; DOWNSTREAM PROCESSING; NONHUMAN; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; RETROVIRUS; SIGNAL TRANSDUCTION;

ANIMALS; B-LYMPHOCYTES; BINDING SITES; CELL LINE; CYTOKINES; MICE; RECEPTORS, CYTOKINE; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION;

MURINAE;

EID: 84859885294     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.24421     Document Type: Article

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