Computational modeling for the optimization of a cardiogenic 3D bioprocess of encapsulated embryonic stem cells

Biomechanics and Modeling in Mechanobiology

Volumn 11, Issue 1-2, 2012, Pages 261-277

  Consolo, F ^a   Bariani, C ^b   Mantalaris, A ^c   Montevecchi, F ^b   Redaelli, A ^a   Morbiducci, U ^b  

^a POLITECNICO DI MILANO   (Italy)

^b POLITECNICO DI TORINO   (Italy)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Cardiac tissue engineering; Computational fluid dynamics; Embryonic stem cell cardiogenesis; Microgravity bioreactors; Transport phenomena

Indexed keywords

BIOREACTORS; CELL ENGINEERING; CHEMICAL ANALYSIS; COMPUTATIONAL FLUID DYNAMICS; COST EFFECTIVENESS; CYTOLOGY; DIFFUSION IN LIQUIDS; MICROGRAVITY PROCESSING; ROTATION; STEM CELLS; TISSUE ENGINEERING; TRANSPORT PROPERTIES;

BIOPROCESSES; CARDIAC TISSUE ENGINEERING; CARDIOGENESIS; COMPUTATIONAL MODELLING; CONDITION; EMBRYONIC STEM CELL CARDIOGENESIS; EMBRYONIC STEM CELLS; MICROGRAVITY BIOREACTOR; OPTIMISATIONS; TRANSPORT PHENOMENON;

MICROGRAVITY;

OXYGEN;

ANIMAL; ARTICLE; BIOLOGICAL MODEL; BIOREACTOR; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; COMPUTER SIMULATION; CULTURE TECHNIQUE; CYTOLOGY; EMBRYONIC STEM CELL; GENE EXPRESSION REGULATION; GENETICS; HEART MUSCLE CELL; IMMOBILIZED CELL; KINETICS; METABOLISM; METHODOLOGY; MOUSE; ORGANOGENESIS; PRESSURE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ROTATION; WEIGHTLESSNESS;

ANIMALS; BIOREACTORS; CELL CULTURE TECHNIQUES; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; CELLS, IMMOBILIZED; COMPUTER SIMULATION; EMBRYONIC STEM CELLS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; KINETICS; MICE; MODELS, BIOLOGICAL; MYOCYTES, CARDIAC; ORGANOGENESIS; OXYGEN; PARTIAL PRESSURE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; ROTATION; WEIGHTLESSNESS;

EID: 84859884733     PISSN: 16177959     EISSN: 16177940     Source Type: Journal    
DOI: 10.1007/s10237-011-0308-0     Document Type: Article

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