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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 9, 2012, Pages 3079-3082

Development of rationally designed DNA N6 adenine methyltransferase inhibitors

(6) Hobley, Gerard a McKelvie, Jennifer C a Harmer, Jenny E a Howe, Jason a Oyston, Petra C F b Roach, Peter L a

a UNIVERSITY OF SOUTHAMPTON (United Kingdom)

b DEFENCE SCIENCE AND TECHNOLOGY LABORATORY (United Kingdom)

Author keywords

Antibacterial; DNA methyltransferases; Epigenetics; Inhibitors; Methylation; S Adenosylmethionine

Indexed keywords

DNA METHYLTRANSFERASE; DNA N6 ADENINE METHYLTRANSFERASE INHIBITOR; ENZYME INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; ENZYME INHIBITION; STRUCTURE ACTIVITY RELATION;

BINDING SITES; DRUG DESIGN; ENZYME INHIBITORS; HUMANS; S-ADENOSYLMETHIONINE; SITE-SPECIFIC DNA-METHYLTRANSFERASE (ADENINE-SPECIFIC); STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 84859878034 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.03.072 Document Type: Article

Times cited : (12)

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