Glucocorticoid receptor isoform expression does not predict steroid treatment response in IBD [12]

Gut

Volumn 56, Issue 9, 2007, Pages 1328-1329

  Hausmann, M ^b   Herfarth, H ^b   Scholmerich J ^b   Rogler, Gerhard ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOCORTICOID RECEPTOR ALPHA; GLUCOCORTICOID RECEPTOR BETA; STEROID;

ENTERITIS; FOLLOW UP; HUMAN; LETTER; MONONUCLEAR CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA ISOLATION; RNA SPLICING; TREATMENT RESPONSE; ULCERATIVE COLITIS;

GENE EXPRESSION; GLUCOCORTICOIDS; HUMANS; INFLAMMATORY BOWEL DISEASES; RECEPTORS, GLUCOCORTICOID; RNA, MESSENGER; TREATMENT OUTCOME;

EID: 34548127056     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.2006.108035     Document Type: Letter

References (5)

1. Sandborn WJ. Steroid-dependent Crohn's disease. Can J Gastroenterol 2000;14(suppl C):17-22C.
2. Hollenberg SM, Weinberger C, Ong ES, et al. Primary structure and expression of a functional human glucocorticoid receptor cDNA. Nature 1985;318:635-41.
3. Bamberger CM, Bamberger AM, de Castro M, et al. Glucocorticoid receptor beta, a potential endogenous inhibitor of glucocorticoid action in humans. J Clin Invest 1995;95:2435-41.
4. Honda M, Orii F, Ayabe T, et al. Expression of glucocorticoid receptor beta in lymphocytes of patients with glucocorticoid-resistant ulcerative colitis. Gastroenterology 2000;118:859-66.
5. Rogler G, Meinel A, Lingauer A, et al. Glucocorticoid receptors are down-regulated in inflamed colonic mucosa but not in peripheral blood mononuclear cells from patients with inflammatory bowel disease. Eur J Clin Invest 1999;29:330-6.