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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 9, 2012, Pages 3157-3162

Design and optimization of quinazoline derivatives as melanin concentrating hormone receptor 1 (MCHR1) antagonists

(19) Sasmal, Sanjita a Balaji, Gade a Kanna Reddy, Hariprasada R a Balasubrahmanyam, D a Srinivas, Gujjary a Shiva K, Kyasa a Sasmal, Pradip K a Khanna, Ish a Talwar, Rashmi a Suresh, J a Jadhav, Vikram P a Muzeeb, Syed a Shashikumar, Dhanya a Harinder Reddy, K a Sebastian, V J a Frimurer, Thomas M b Rist, Øystein b Elster, Lisbeth b Högberg, Thomas b,c

a DR REDDY'S LABORATORIES LTD (India)

b 7TM Pharma A S (Denmark)

c LEO PHARMA A S (Denmark)

Author keywords

MCH receptor ensembles; MCHR1 antagonists; Melanin concentrating hormone (MCH); Obesity

Indexed keywords

GW 856464; LEAD; MELANIN CONCENTRATING HORMONE; MELANIN CONCENTRATING HORMONE RECEPTOR 1 ANTAGONIST; QUINAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG DESIGN; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG SYNTHESIS; HOMEOSTASIS; WEIGHT REDUCTION; X RAY ANALYSIS;

EID: 84859811637 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.03.050 Document Type: Article

Times cited : (42)

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