Molecular dynamics simulations of the coenzyme induced conformational changes of Mycobacterium tuberculosis L-alanine dehydrogenase

Journal of Molecular Graphics and Modelling

Volumn 35, Issue , 2012, Pages 1-10

  Ling, Baoping ^a   Sun, Min ^a   Bi, Siwei ^a   Jing, Zhihong ^a   Liu, Yongjun ^b,c  

^a QUFU NORMAL UNIVERSITY   (China)

^b NORTHWEST INSTITUTE OF PLATEAU BIOLOGY   (China)

^c SHANDONG UNIVERSITY   (China)

Author keywords

Free energy landscape; L Alanine dehydrogenase; Molecular dynamics simulations; Mycobacterium tuberculosis; Principle component analysis

Indexed keywords

FREE ENERGY LANDSCAPE; L-ALANINE; MOLECULAR DYNAMICS SIMULATIONS; MYCOBACTERIUM TUBERCULOSIS; PRINCIPLE COMPONENT ANALYSIS;

MOLECULAR DYNAMICS; NEMATIC LIQUID CRYSTALS; PRINCIPAL COMPONENT ANALYSIS; TUBES (COMPONENTS);

AMINO ACIDS;

ALANINE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE;

AMINO ACID SEQUENCE; ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME BINDING; ENZYME CONFORMATION; ENZYME STABILITY; ENZYME SUBSTRATE COMPLEX; MOLECULAR DYNAMICS; MOLECULAR MODEL; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; PROTEIN DOMAIN;

ALANINE DEHYDROGENASE; ALGORITHMS; BACTERIAL PROTEINS; BINDING SITES; ENZYME STABILITY; HYDROGEN BONDING; MOLECULAR DYNAMICS SIMULATION; MYCOBACTERIUM TUBERCULOSIS; NAD; PRINCIPAL COMPONENT ANALYSIS; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; THERMODYNAMICS; WATER;

MYCOBACTERIUM TUBERCULOSIS;

EID: 84859789791     PISSN: 10933263     EISSN: 18734243     Source Type: Journal    
DOI: 10.1016/j.jmgm.2012.01.005     Document Type: Article

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