Domain motions of hyaluronan lyase underlying processive hyaluronan translocation

Proteins: Structure, Function and Bioinformatics

Volumn 76, Issue 1, 2009, Pages 30-46

  Joshi, Harshad V ^a,b   Jedrzejas, Mark J ^c   De Groot, Bert L ^a  

^a MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^b UNIVERSITY OF CINCINNATI   (United States)

^c CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

Author keywords

Essential dynamics; Force probe; Free energy; Molecular dynamics; Principle component analysis; Processivity; Simulation; Sugar degradation; Umbrella sampling

Indexed keywords

BACTERIAL PROTEIN; CHONDROITIN; CHONDROITIN SULFATE; DISACCHARIDE; HYALURONAN LYASE; HYALURONIC ACID; MEMBRANE PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CATALYSIS; CONFORMATIONAL TRANSITION; CORRELATION ANALYSIS; CRYSTAL STRUCTURE; ENDOLYSIS; ENZYME ACTIVITY; EXOLYSIS; EXTRACELLULAR MATRIX; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NONHUMAN; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN STRUCTURE; STREPTOCOCCUS; STREPTOCOCCUS PNEUMONIAE;

COMPUTER SIMULATION; HYALURONIC ACID; MODELS, MOLECULAR; POLYSACCHARIDE-LYASES; PROTEIN STRUCTURE, TERTIARY; STREPTOCOCCUS PNEUMONIAE; THERMODYNAMICS;

BACTERIA (MICROORGANISMS); STREPTOCOCCUS; STREPTOCOCCUS PNEUMONIAE;

EID: 66249109589     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.22316     Document Type: Article

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