메뉴 건너뛰기




Volumn 60, Issue 9, 2012, Pages 2136-2147

In vitro fermentation of a red wine extract by human gut microbiota: Changes in microbial groups and formation of phenolic metabolites

Author keywords

Anthocyanins; Fecal bacteria; Fermentation; Flavan 3 ols; Microbial catabolism; Red wine

Indexed keywords

3 ,4-DIHYDROXYPHENYLACETIC ACIDS; BATCH CULTURE; BENZOIC ACID; FECAL BACTERIA; FLAVAN-3-OLS; HUMAN GUTS; IN-VITRO; INOCULA; MICROBIAL CATABOLISM; MICROBIAL GROUPS; MICROBIOTAS; PHENOLIC METABOLITES; POLYPHENOLS; RED WINE; VALERIC ACIDS;

EID: 84859768816     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf2040115     Document Type: Article
Times cited : (156)

References (43)
  • 1
    • 0026651085 scopus 로고
    • Wine alcohol, platelets, and the French paradox for coronary heart disease
    • Renaud, S.; De Lorgeril, M. Wine, alcohol, platelets, and the French paradox for coronary heart disease. Lancet 1992, 339, 1523-1526.
    • (1992) Lancet , vol.339 , pp. 1523-1526
    • Renaud, S.1    De Lorgeril, M.2
  • 5
    • 2942511952 scopus 로고    scopus 로고
    • Different effects of red wine and gin consumption on inflammatory biomarkers of atherosclerosis: A prospective randomized crossover trial: Effects of wine on inflammatory markers
    • DOI 10.1016/j.atherosclerosis.2004.03.006, PII S0021915004001467
    • Estruch, R.; Sacanella, E.; Badia, E.; Antúnez, E.; Nicolás, J. M.; Fernández-Solá, J.; Rotilio, D.; De Gaetano, G.; Rubin, E.; Urbano-Márquez, A. Different effects of red wine and gin consumption on inflammatory biomarkers of atherosclerosis: A prospective randomized crossover trial: Effects of wine on inflammatory markers. Atherosclerosis 2004, 175, 117-123. (Pubitemid 38746918)
    • (2004) Atherosclerosis , vol.175 , Issue.1 , pp. 117-123
    • Estruch, R.1    Sacanella, E.2    Badia, E.3    Antunez, E.4    Nicolas, J.M.5    Fernandez-Sola, J.6    Rotilio, D.7    De Gaetano, G.8    Rubin, E.9    Urbano-Marquez, A.10
  • 7
    • 0032911543 scopus 로고    scopus 로고
    • Study of wine tannin oligomers by on-line liquid chromatography electrospray ionization mass spectrometry
    • DOI 10.1021/jf9805496
    • Fulcrand, H.; Remy, S.; Souquet, J. M.; Cheynier, V.; Moutounet, M. Study of wine tannin oligomers by on-line liquid chromatography electrospray ionization mass spectrometry. J. Agric. Food. Chem. 1999, 47, 1023-1028. (Pubitemid 29182957)
    • (1999) Journal of Agricultural and Food Chemistry , vol.47 , Issue.3 , pp. 1023-1028
    • Fulcrand, H.1    Remy, S.2    Souquet, J.-M.3    Cheynier, V.4    Moutounet, M.5
  • 8
    • 78049432112 scopus 로고    scopus 로고
    • Colonic metabolites of berry polyphenols: The missing link to biological activity ?
    • Williamson, G.; Clifford, M. N. Colonic metabolites of berry polyphenols: the missing link to biological activity ? Br. J. Nutr. 2010, S48-s66.
    • (2010) Br. J. Nutr.
    • Williamson, G.1    Clifford, M.N.2
  • 10
    • 84890305188 scopus 로고    scopus 로고
    • Absorption and metabolism of dietary plant secondary metabolites
    • Crozier, A., Clifford, M. N., Ashihara, H., Eds. Blackwell Publishing Ltd: Oxford, UK
    • Donovan, J. L.; Manach, C.; Faulks, R. M.; Kroon, P. A. Absorption and Metabolism of Dietary Plant Secondary Metabolites. In Plant Secondary Metabolites. Occurrence, Structure and Role in the Human Diet; Crozier, A., Clifford, M. N., Ashihara, H., Eds.; Blackwell Publishing Ltd: Oxford, UK, 2006; pp 303-341.
    • (2006) Plant Secondary Metabolites. Occurrence, Structure and Role in the Human Diet , pp. 303-341
    • Donovan, J.L.1    Manach, C.2    Faulks, R.M.3    Kroon, P.A.4
  • 11
    • 0033745131 scopus 로고    scopus 로고
    • Polymeric proanthocyanidins are catabolized by human colonic microflora into low-molecular-weight phenolic acids
    • Déprez, S.; Brezillon, C.; Rabot, S.; Philippe, C.; Mila, I.; Lapierre, C.; Scalbert, A. Polymeric proanthocyanidins are catabolized by human colonic microflora into low-molecular-weight phenolic acids. J. Nutr. 2000, 130, 2733-2738.
    • (2000) J. Nutr. , vol.130 , pp. 2733-2738
    • Déprez, S.1    Brezillon, C.2    Rabot, S.3    Philippe, C.4    Mila, I.5    Lapierre, C.6    Scalbert, A.7
  • 13
    • 41249083356 scopus 로고    scopus 로고
    • Microbial metabolism of catechin stereoisomers by human faecal microbiota: Comparison of targeted analysis and a non-targeted metabolomics method
    • DOI 10.1016/j.phytol.2007.12.001, PII S1874390007000055
    • Aura, A. M.; Mattila, I.; Seppänen-Laakso, T.; Miettinen, J.; Oksman-Caldentey, K. M.; Oresic, M. Microbial metabolism of catechin stereoisomers by human faecal microbiota: Comparison of targeted analysis and a non-targeted metabolomics method. Phytochem. Lett. 2008, 1, 18-22. (Pubitemid 351445363)
    • (2008) Phytochemistry Letters , vol.1 , Issue.1 , pp. 18-22
    • Aura, A.-M.1    Mattila, I.2    Seppanen-Laakso, T.3    Miettinen, J.4    Oksman-Caldentey, K.-M.5    Oresic, M.6
  • 14
    • 68249114506 scopus 로고    scopus 로고
    • Interaction between phenolics and gut microbiota: Role in human health
    • Selma, M. V.; Espín, J. C.; Tomás-Barberán, F. A. Interaction between phenolics and gut microbiota: Role in human health. J. Agric. Food. Chem. 2009, 57, 6485-6501.
    • (2009) J. Agric. Food. Chem. , vol.57 , pp. 6485-6501
    • Selma, M.V.1    Espín, J.C.2    Tomás-Barberán, F.A.3
  • 16
    • 0031320238 scopus 로고    scopus 로고
    • Influence of tea catechins on the digestive tract
    • DOI 10.1002/(SICI)1097-4644(1997)27+<52::AID-JCB10>3.0.CO;2-N
    • Hara, Y. Influence of tea catechins on the digestive tract. J. Cell. Biochem. 1997, 67, 52-58. (Pubitemid 28222119)
    • (1997) Journal of Cellular Biochemistry , vol.67 , Issue.SUPPL. 27 , pp. 52-58
    • Hara, Y.1
  • 17
    • 77956870901 scopus 로고    scopus 로고
    • The ability of blackcurrant extracts to positively modulate key markers of gastrointestinal function in rats
    • Molan, A. L.; Liu, Z.; Kruger, M. The ability of blackcurrant extracts to positively modulate key markers of gastrointestinal function in rats. World J. Microbiol. Biotechnol. 2011, 26, 1735-1743.
    • (2011) World J. Microbiol. Biotechnol. , vol.26 , pp. 1735-1743
    • Molan, A.L.1    Liu, Z.2    Kruger, M.3
  • 18
    • 79951759025 scopus 로고    scopus 로고
    • Effects of dietary polyphenol-rich grape products on intestinal microflora and gut morphology in broiler chicks
    • Viveros, A.; Chamorro, S.; Pizarro, M.; Arija, I.; Centeno, C.; Brenes, A. Effects of dietary polyphenol-rich grape products on intestinal microflora and gut morphology in broiler chicks. Poult. Sci. 2011, 90, 566-578.
    • (2011) Poult. Sci. , vol.90 , pp. 566-578
    • Viveros, A.1    Chamorro, S.2    Pizarro, M.3    Arija, I.4    Centeno, C.5    Brenes, A.6
  • 19
    • 78651309432 scopus 로고    scopus 로고
    • Prebiotic evaluation of cocoa-derived flavanols in healthy humans by using a randomized, controlled, doubleblind, crossover intervention study
    • Tzounis, X.; Rodriguez-Mateos, A.; Vulevic, J.; Gibson, G. R.; Kwik-Uribe, C.; Spencer, J. P. E. Prebiotic evaluation of cocoa-derived flavanols in healthy humans by using a randomized, controlled, doubleblind, crossover intervention study. Am. J. Clin. Nutr. 2011, 93, 62-72.
    • (2011) Am. J. Clin. Nutr. , vol.93 , pp. 62-72
    • Tzounis, X.1    Rodriguez-Mateos, A.2    Vulevic, J.3    Gibson, G.R.4    Kwik-Uribe, C.5    Spencer, J.P.E.6
  • 21
    • 9344247522 scopus 로고    scopus 로고
    • Application of a suite of 16S rRNA-specific oligonucleotide probes designed to investigate bacteria of the phylum cytophaga-flavobacter-bacteroides in the natural environment
    • Manz, W.; Amann, R.; Ludwig, W.; Vancanneyt, M.; Schleifer, K. H. Application of a suite of 16S rRNA-specific oligonucleotide probes designed to investigate bacteria of the phylum cytophagaflavobacter- bacteroides in the natural environment. Microbiology 1996, 142, 1097-1106. (Pubitemid 26154919)
    • (1996) Microbiology , vol.142 , Issue.5 , pp. 1097-1106
    • Manz, W.1    Amann, R.2    Ludwig, W.3    Vancanneyt, M.4    Schleifer, K.-H.5
  • 22
    • 0033034862 scopus 로고    scopus 로고
    • A 16S rRNA-targeted probe for detection of lactobacilli and enterococci in faecal samples by fluorescent in situ hybridization
    • DOI 10.1080/089106099435862
    • Harmsen, H. J. M.; Elfferich, P.; Schut, F.; Welling, G. W. A 16S rRNA-targeted probe for detection of lactobacilli and enterococci in faecal samples by fluorescent in situ hybridization. Microb. Ecol. Health Dis. 1999, 11, 3-12. (Pubitemid 29248950)
    • (1999) Microbial Ecology in Health and Disease , vol.11 , Issue.1 , pp. 3-12
    • Harmsen, H.J.M.1    Elfferich, P.2    Schut, F.3    Welling, G.W.4
  • 23
    • 0031692488 scopus 로고    scopus 로고
    • Variations of bacterial populations in human feces measured by fluorescent in situ hybridization with group-specific 16S rRNA-targeted oligonucleotide probes
    • Franks, A. H.; Harmsen, H. J. M.; Raangs, G. C.; Jansen, G. J.; Schut, F.; Welling, G. W. Variations of bacterial populations in human feces measured by fluorescent in situ hybridization with group-specific 16S rRNA-targeted oligonucleotide probes. Appl. Environ. Microbiol. 1998, 64, 3336-3345. (Pubitemid 28411456)
    • (1998) Applied and Environmental Microbiology , vol.64 , Issue.9 , pp. 3336-3345
    • Franks, A.H.1    Harmsen, H.J.M.2    Raangs, G.C.3    Jansen, G.J.4    Schut, F.5    Welling, G.W.6
  • 24
    • 0344172842 scopus 로고    scopus 로고
    • The domain-specific probe EUB338 is insufficient for the detection of all bacteria: Development and evaluation of a more comprehensive probe set
    • Daims, H.; Brühl, A.; Amann, R.; Schleifer, K. H.; Wagner, M. The domain-specific probe EUB338 is insufficient for the detection of all bacteria: Development and evaluation of a more comprehensive probe set. Syst. Appl. Microbiol. 1999, 22, 434-444. (Pubitemid 29485930)
    • (1999) Systematic and Applied Microbiology , vol.22 , Issue.3 , pp. 434-444
    • Daims, H.1    Bruhl, A.2    Amann, R.3    Schleifer, K.-H.4    Wagner, M.5
  • 26
    • 80054042848 scopus 로고    scopus 로고
    • Gut microbial catabolism of grape seed flavan-3-ols by human faecal microbiota. Targeted analysis of precursor compounds, intermediate metabolites and end products
    • Sánchez-Patán, F.; Cueva, C.; Monagas, M.; Walton, G. E.; Gibson, G. R.; Martín-A ìlvarez, P. J.; Moreno-Arribas, M.-V.; Bartolomé, B. Gut microbial catabolism of grape seed flavan-3-ols by human faecal microbiota. Targeted analysis of precursor compounds, intermediate metabolites and end products. Food Chem. 2012, 131, 337-347.
    • (2012) Food Chem. , vol.131 , pp. 337-347
    • Sánchez-Patán, F.1    Cueva, C.2    Monagas, M.3    Walton, G.E.4    Gibson, G.R.5    Martín-Aìlvarez, P.J.6    Moreno-Arribas, M.-V.7    Bartolomé, B.8
  • 27
    • 74849092330 scopus 로고    scopus 로고
    • Green tea flavan-3-ols: Colonic degradation and urinary excretion of catabolites by humans
    • Roowi, S.; Stalmach, A.; Mullen, W.; Lean, M. E. J.; Edwards, C. A.; Crozier, A. Green tea flavan-3-ols: Colonic degradation and urinary excretion of catabolites by humans. J. Agric. Food. Chem. 2010, 58, 1296-1304.
    • (2010) J. Agric. Food. Chem. , vol.58 , pp. 1296-1304
    • Roowi, S.1    Stalmach, A.2    Mullen, W.3    Lean, M.E.J.4    Edwards, C.A.5    Crozier, A.6
  • 29
    • 22844442338 scopus 로고    scopus 로고
    • Metabolism of anthocyanins and their phenolic degradation products by the intestinal microflora
    • DOI 10.1016/j.bmc.2005.05.003, PII S0968089605003986
    • Keppler, K.; Humpf, H. U. Metabolism of anthocyanins and their phenolic degradation products by the intestinal microflora. Bioorg. Med. Chem. 2005, 13, 5195-205. (Pubitemid 41039980)
    • (2005) Bioorganic and Medicinal Chemistry , vol.13 , Issue.17 , pp. 5195-5205
    • Keppler, K.1    Humpf, H.-U.2
  • 30
    • 77956170874 scopus 로고    scopus 로고
    • Procyanidin B2 catabolism by human fecal microflora: Partial characterization of 'dimeric' intermediates
    • Stoupi, S.; Williamson, G.; Drynan, J. W.; Barron, D.; Clifford, M. N. Procyanidin B2 catabolism by human fecal microflora: Partial characterization of 'dimeric' intermediates. Arch. Biochem. Biophys. 2010, 501, 73-78.
    • (2010) Arch. Biochem. Biophys. , vol.501 , pp. 73-78
    • Stoupi, S.1    Williamson, G.2    Drynan, J.W.3    Barron, D.4    Clifford, M.N.5
  • 31
    • 0031009218 scopus 로고    scopus 로고
    • Biotransformation of (-)-epicatechin 3-O-gallate by human intestinal bacteria
    • Meselhy, M. R.; Nakamura, N.; Hattori, M. Biotransformation of (-)-epicatechin 3-O-gallate by human intestinal bacteria. Chem. Pharm. Bull. 1997, 45, 888-893. (Pubitemid 27255104)
    • (1997) Chemical and Pharmaceutical Bulletin , vol.45 , Issue.5 , pp. 888-893
    • Meselhy, M.R.1    Nakamura, N.2    Hattori, M.3
  • 32
    • 74849132800 scopus 로고    scopus 로고
    • Metabolism of (-)-epigallocatechin gallate by rat intestinal flora
    • Takagaki, A.; Nanjo, F. Metabolism of (-)-epigallocatechin gallate by rat intestinal flora. J. Agric. Food. Chem. 2010, 58, 1313-1321.
    • (2010) J. Agric. Food. Chem. , vol.58 , pp. 1313-1321
    • Takagaki, A.1    Nanjo, F.2
  • 33
    • 61449211248 scopus 로고    scopus 로고
    • Procyanidin dimers are metabolized by human microbiota with 2-3,4-dihydroxyphenyl)acetic acid and 5-3,4-dihydroxyphenyl)-γ- valerolactone as the major metabolites
    • Appeldoorn, M. M.; Vincken, J. P.; Aura, A. M.; Hollman, P. C. H.; Gruppen, H. Procyanidin dimers are metabolized by human microbiota with 2-(3,4-dihydroxyphenyl)acetic acid and 5-(3,4-dihydroxyphenyl)-γ- valerolactone as the major metabolites. J. Agric. Food. Chem. 2009, 57, 1084-1092.
    • (2009) J. Agric. Food. Chem. , vol.57 , pp. 1084-1092
    • Appeldoorn, M.M.1    Vincken, J.P.2    Aura, A.M.3    Hollman, P.C.H.4    Gruppen, H.5
  • 34
    • 34648835415 scopus 로고    scopus 로고
    • Polyphenols modulate calcium-independent mechanisms in human arterial tissue-engineered vascular media
    • DOI 10.1016/j.jvs.2007.05.031, PII S0741521407009597
    • Diebolt, M.; Laflamme, K.; Labbe, R.; Auger, F. A.; Germain, L.; Andriantsitohaina, R. Polyphenols modulate calcium-independent mechanisms in human arterial tissue-engineered vascular media. J. Vasc. Surg. 2007, 46, 764-72. (Pubitemid 47454691)
    • (2007) Journal of Vascular Surgery , vol.46 , Issue.4 , pp. 764-772
    • Diebolt, M.1    Laflamme, K.2    Labbe, R.3    Auger, F.A.4    Germain, L.5    Andriantsitohaina, R.6
  • 35
    • 48449083346 scopus 로고    scopus 로고
    • Microbial metabolism of dietary phenolic compounds in the colon
    • Aura, A. M. Microbial metabolism of dietary phenolic compounds in the colon. Phytochem. Rev. 2008, 7, 407-429.
    • (2008) Phytochem. Rev. , vol.7 , pp. 407-429
    • Aura, A.M.1
  • 36
    • 0037316953 scopus 로고    scopus 로고
    • Microbial aromatic acid metabolites formed in the gut account for a major fraction of the polyphenols excreted in urine of rats fed red wine polyphenols
    • Gonthier, M. P.; Cheynier, V.; Donovan, J. L.; Manach, C.; Morand, C.; Mila, I.; Lapierre, C.; Rémésy, C.; Scalbert, A. Microbial aromatic acid metabolites formed in the gut account for a major fraction of the polyphenols excreted in urine of rats fed red wine polyphenols. J. Nutr. 2003, 133, 461-467. (Pubitemid 36172900)
    • (2003) Journal of Nutrition , vol.133 , Issue.2 , pp. 461-467
    • Gonthier, M.-P.1    Cheynier, V.2    Donovan, J.L.3    Manach, C.4    Morand, C.5    Mila, I.6    Lapierre, C.7    Remesy, C.8    Scalbert, A.9
  • 37
    • 77956637099 scopus 로고    scopus 로고
    • In vitro bioconversion of polyphenols from black tea and red wine/grape juice by human intestinal microbiota displays strong interindividual variability
    • Gross, G.; Jacobs, D. M.; Peters, S.; Possemiers, S.; Van Duynhoven, J.; Vaughan, E. E.; Van De Wiele, T. In vitro bioconversion of polyphenols from black tea and red wine/grape juice by human intestinal microbiota displays strong interindividual variability. J. Agric. Food. Chem. 2010, 58, 10236-10246.
    • (2010) J. Agric. Food. Chem. , vol.58 , pp. 10236-10246
    • Gross, G.1    Jacobs, D.M.2    Peters, S.3    Possemiers, S.4    Van Duynhoven, J.5    Vaughan, E.E.6    Van De Wiele, T.7
  • 38
    • 0017297766 scopus 로고
    • Study of the intestinal tyrosine metabolism using stable isotopes and gas chromatographymass spectrometry
    • Curtius, H. C.; Mettler, M.; Ettlinger, L. Study of the intestinal tyrosine metabolism using stable isotopes and gas chromatographymass spectrometry. J. Chromatogr., A 1976, 126, 569-580.
    • (1976) J. Chromatogr., A , vol.126 , pp. 569-580
    • Curtius, H.C.1    Mettler, M.2    Ettlinger, L.3
  • 39
    • 32344444354 scopus 로고    scopus 로고
    • Stability and biotransformation of various dietary anthocyanins in vitro
    • DOI 10.1007/s00394-005-0557-8
    • Fleschhut, J.; Kratzer, F.; Rechkemmer, G.; Kulling, S. E. Stability and biotransformation of various dietary anthocyanins in vitro. Eur. J. Nutr. 2006, 45, 7-18. (Pubitemid 43221279)
    • (2006) European Journal of Nutrition , vol.45 , Issue.1 , pp. 7-18
    • Fleschhut, J.1    Kratzer, F.2    Rechkemmer, G.3    Kulling, S.E.4
  • 42
    • 4143081627 scopus 로고    scopus 로고
    • Supplementation with grape seed polyphenols results in increased urinary excretion of 3-hydroxyphenylpropionic acid, an important metabolite of proanthocyanidins in humans
    • Ward, N. C.; Croft, K. D.; Puddey, I. B.; Hodgson, J. M. Supplementation with grape seed polyphenols results in increased urinary excretion of 3-hydroxyphenylpropionic acid, an important metabolite of proanthocyanidins in humans. J. Agric. Food. Chem. 2004, 52, 5545-5549.
    • (2004) J. Agric. Food. Chem. , vol.52 , pp. 5545-5549
    • Ward, N.C.1    Croft, K.D.2    Puddey, I.B.3    Hodgson, J.M.4
  • 43
    • 79958812230 scopus 로고    scopus 로고
    • Isolation of catechin-converting human intestinal bacteria
    • Kutschera, M.; Engst, W.; Blaut, M.; Braune, A. Isolation of catechin-converting human intestinal bacteria. J. Appl. Microbiol. 2011, 111, 165-75.
    • (2011) J. Appl. Microbiol. , vol.111 , pp. 165-175
    • Kutschera, M.1    Engst, W.2    Blaut, M.3    Braune, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.