ORAI1 Ca2+ channels control endothelin-1-induced mitogenesis and melanogenesis in primary human melanocytes

Journal of Investigative Dermatology

Volumn 132, Issue 5, 2012, Pages 1443-1451

  Stanisz, Hedwig ^a   Stark, Alexandra ^a   Kilch, Tatiana ^a   Schwarz, Eva C ^a   Müller, Cornelia S L ^a   Peinelt, Christine ^a   Hoth, Markus ^a   Niemeyer, Barbara A ^a   Vogt, Thomas ^a   Bogeski, Ivan ^a  

^a SAARLAND UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINOETHOXYDIPHENYLBORANE; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL 1; ENDOTHELIN 1; MELANIN; MESSENGER RNA; MONOPHENOL MONOOXYGENASE; SMALL INTERFERING RNA; STROMAL INTERACTION MOLECULE 1; STROMAL INTERACTION MOLECULE 2;

ARTICLE; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN TISSUE; MELANOCYTE; MELANOGENESIS; MITOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 84859764219     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2011.478     Document Type: Article

References (58)

1. Allen DH, Lepple-Wienhues A, Cahalan MD (1997) Ion channel phenotype of melanoma cell lines. J Membr Biol 155:27-34 (Pubitemid 27046529)
2. Arozarena I, Sanchez-Laorden B, Packer L et al. (2011) Oncogenic BRAF induces melanoma cell invasion by downregulating the cGMP-specific phosphodiesterase PDE5A. Cancer Cell 19:45-57
3. Berna-Erro A, Braun A, Kraft R et al. (2009) STIM2 regulates capacitive Ca2+ entry in neurons and plays a key role in hypoxic neuronal cell death. Sci Signal 2:ra67
4. Bogeski I, Kummerow C, Al-Ansary D et al. (2010) Differential redox regulation of ORAI ion channels: a mechanism to tune cellular calcium signaling. Sci Signal 3:ra24
5. Deli T, Varga N Á dám A, Kenessey I et al. (2007) Functional genomics of calcium channels in human melanoma cells. Int J Cancer 121: 55-65 (Pubitemid 46753851)
6. Demunter A, De Wolf-Peeters C, Degreef H et al. (2001) Expression of the endothelin-B receptor in pigment cell lesions of the skin. Virchows Archiv 438:485-91
7. Devi S, Kedlaya R, Maddodi N et al. (2009) Calcium homeostasis in human melanocytes: role of transient receptor potential melastatin 1 (TRPM1) and its regulation by ultraviolet light. Am J Physiol Cell Physiol 297:C679-87
8. Dougherty MK, Ritt DA, Zhou M et al. (2009) KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals. Mol Cell 34:652-62
9. Fazal N, Slominski A, Choudhry MA et al. (1998) Effect of CRF and related peptides on calcium signaling in human and rodent melanoma cells. FEBS Lett 435:187-90 (Pubitemid 28436580)
10. Feldman B, Fedida-Metula S, Nita J et al. (2010) Coupling of mitochondria to store-operated Ca2+-signaling sustains constitutive activation of protein kinase B/Akt and augments survival of malignant melanoma cells. Cell Calcium 47:525-37
11. Feng M, Grice DM, Faddy HM et al. (2010) Store-independent activation of Orai1 by SPCA2 in mammary tumors. Cell 143:84-98
12. Feske S, Gwack Y, Prakriya M et al. (2006) A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. Nature 441:179-85
13. Grynkiewicz G, Poenie M, Tsien RY (1985) A new generation of Ca2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-50 (Pubitemid 15114340)
14. Gwack Y, Srikanth S, Oh-hora M et al. (2008) Hair loss and defective T-and B-cell function in mice lacking ORAI1. Mol Cell Biol 28: 5209-22
15. Hirobe T (2011) How are proliferation and differentiation of melanocytes regulated? Pigment Cell Melanoma Res 24:462-78
16. Hoogduijn MJ, Cemeli E, Ross K et al. (2004) Melanin protects melanocytes and keratinocytes against H2O2-induced DNA strand breaks through its ability to bind Ca2+. Exp Cell Res 294:60-7 (Pubitemid 38229780)
17. Hoth M, Penner R (1992) Depletion of intracellular calcium stores activates a calcium current in mast cells. Nature 355:353-6
18. Imokawa G, Kobayasi T, Miyagishi M (2000) Intracellular signaling mechanisms leading to synergistic effects of endothelin-1 and stem cell factor on proliferation of cultured human melanocytes. Cross-talk via trans-activation of the tyrosine kinase c-kit receptor. J Biol Chem 275:33321-8
19. Imokawa G, Miyagishi M, Yada Y (1995) Endothelin-1 as a new melanogen: coordinated expression of its gene and the tyrosinase gene in UVBexposed human epidermis. J Invest Dermatol 105:32-7
20. Imokawa G, Yada Y, Miyagishi M (1992) Endothelins secreted from human keratinocytes are intrinsic mitogens for human melanocytes. J Biol Chem 267:24675-80
21. Kadekaro AL, Kavanagh R, Kanto H et al. (2005) alpha-Melanocortin and endothelin-1 activate antiapoptotic pathways and reduce DNA damage in human melanocytes. Cancer Res 65:4292-9 (Pubitemid 40775668)
22. Kang H-Y, Kang W-H, Lee CO (1998) Endothelin-B receptor-mediated Ca2+ signaling in human melanocytes. Pflügers Arch 435:350-6 (Pubitemid 28066225)
23. Lahav R, Suvà M-L, Rimoldi D et al. (2004) Endothelin receptor B inhibition triggers apoptosis and enhances angiogenesis in melanomas. Cancer Res 64:8945-53 (Pubitemid 39665502)
24. Levin ER (1995) Endothelins. N Engl J Med 333:356-63
25. Liou J, Kim ML, Heo WD et al. (2005) STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx. Curr Biol 15:1235-41 (Pubitemid 40950523)
26. McCarl CA, Picard C, Khalil S et al. (2009) ORAI1 deficiency and lack of store-operated Ca2+ entry cause immunodeficiency, myopathy, and ectodermal dysplasia. J Allergy Clin Immunol 124:1311-8
27. Motiani RK, Abdullaev IF, Trebak M (2010) A novel native store-operated calcium channel encoded by Orai3. J Biol Chem 285:19173-83
28. Nilius B, Schwarz G, Droogmans G (1993) Control of intracellular calcium by membrane potential in human melanoma cells. Am J Physiol 265:C1501-C10
29. Oancea E, Vriens J, Brauchi S et al. (2009) TRPM1 forms ion channels associated with melanin content in melanocytes. Sci Signal 2:ra21
30. Oh-hora M, Yamashita M, Hogan PG et al. (2008) Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance. Nat Immunol 9:432-43 (Pubitemid 351405113)
31. Parekh AB, Putney Jr JW (2005) Store-operated calcium channels. Physiol Rev 85:757-810 (Pubitemid 40404641)
32. Park CY, Shcheglovitov A, Dolmetsch R (2010) The CRAC channel activator STIM1 binds and inhibits L-Type voltage-gated calcium channels. Science 330:101-5
33. Picard C, McCarl CA, Papolos A et al. (2009) STIM1 mutation associated with a syndrome of immunodeficiency and autoimmunity. N Engl J Med 360:1971-80
34. Prakriya M, Lewis RS (2001) Potentiation and inhibition of Ca(2+) releaseactivated Ca(2+) channels by 2-aminoethyldiphenyl borate (2-APB) occurs independently of IP(3) receptors. J Physiol 536:3-19 (Pubitemid 32952214)
35. Prevarskaya N, Skryma R, Shuba Y (2011) Calcium in tumour metastasis: new roles for known actors. Nat Rev Cancer 11:609-18
36. Rubanyi GM, Polokoff MA (1994) Endothelins: molecular biology, biochemistry, pharmacology, physiology, and pathophysiology. Pharmacol Rev 46:325-415
37. Sato-Jin K, Nishimura EK, Akasaka E et al. (2008) Epistatic connections between microphthalmia-associated transcription factor and endothelin signaling in Waardenburg syndrome and other pigmentary disorders. FASEB J 22:1155-68 (Pubitemid 351519970)
38. Schallreuter KU, Kothari S, Chavan B et al. (2008) Regulation of melanogenesis-controversies and new concepts. Exp Dermatol 17:395-404 (Pubitemid 351513953)
39. Schallreuter KU, Wood JM (1999) The importance of L-phenylalanine transport and its autocrine turnover to L-tyrosine for melanogenesis in human epidermal melanocytes. Biochem Biophys Res Commun 262:423-8 (Pubitemid 29429884)
40. Schallreuter KU, Wood JM, Ehrke C et al. (1992) Calcium transport and regulation in human primary and metastatic melanoma. Biochim Biophys Acta 1160:127-33
41. Slominski A, Tobin DJ, Shibahara S et al. (2004) Melanin pigmentation in mammalian skin and its hormonal regulation. Physiol Rev 84: 1155-228 (Pubitemid 39287950)
42. Slominski A, Wortsman J, Luger T et al. (2000) Corticotropin releasing hormone and proopiomelanocortin involvement in the cutaneous response to stress. Physiol Rev 80:979-1020 (Pubitemid 30452009)
43. Slominski A, Zbytek B, Pisarchik A et al. (2006) CRH functions as a growth factor/cytokine in the skin. J Cell Physiol 206:780-91 (Pubitemid 43191053)
44. Somlyo AP, Somlyo AV (2003) Ca2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase. Physiol Rev 83:1325-58 (Pubitemid 37222274)
45. Spinella F, Rosanò L, Di Castro V et al. (2007) Endothelin-1 and endothelin-3 promote invasive behavior via hypoxia-inducible factor-1a in human melanoma cells. Cancer Res 67:1725-34 (Pubitemid 46383399)
46. Suyama E, Wadhwa R, Kaur K et al. (2004) Identification of metastasis-related genes in a mouse model using a library of randomized ribozymes. J Biol Chem 279:38083-6 (Pubitemid 39295950)
47. Tada A, Pereira E, Beitner-Johnson D et al. (2002) Mitogen-and ultraviolet-Binduced signaling pathways in normal human melanocytes. J Invest Dermatol 118:316-22 (Pubitemid 34158487)
48. Vig M, Peinelt C, Beck A et al. (2006) CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry. Science 312:1220-3 (Pubitemid 43801149)
49. Wang Y, Deng X, Mancarella S et al. (2010) The calcium store sensor, STIM1, reciprocally controls Orai and CaV1.2 channels. Science 330:105-9
50. Watts SW (2010) Endothelin receptors: what's new and what do we need to know? Am J Physiol Regul Integr Comp Physiol 298:R254-60
51. Wiesner B, Roloff B, Fechner K et al. (2003) Intracellular calcium measurements of single human skin cells after stimulation with corticotropin-releasing factor and urocortin using confocal laser scanning microscopy. J Cell Sci 116:1261-8 (Pubitemid 36410664)
52. Worley PF, Zeng W, Huang GN et al. (2007) TRPC channels as STIM1-regulated store-operated channels. Cell Calcium 42:205-11 (Pubitemid 47029603)
53. Yada Y, Higuchi K, Imokawa G (1991) Effects of endothelins on signal transduction and proliferation in human melanocytes. J Biol Chem 266:18352-7 (Pubitemid 21908087)
54. Yanagisawa M, Kurihara H, Kimura S et al. (1988) A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 332:411-5 (Pubitemid 18090241)
55. Yang S, Zhang JJ, Huang X-Y (2009) Orai1 and STIM1 are critical for breast tumor cell migration and metastasis. Cancer Cell 15:124-34
56. Zbytek B, Wortsman J, Slominski A (2006) Characterization of a ultraviolet Binduced corticotropin-releasing hormone-proopiomelanocortin system in human melanocytes. Mol Endocrinol 20:2539-47 (Pubitemid 44496421)
57. Zhang SL, Yeromin AV, Zhang XH et al. (2006) Genome-wide RNAi screen of Ca(2+) influx identifies genes that regulate Ca(2+) release-activated Ca(2+) channel activity. Proc Natl Acad Sci USA 103:9357-62 (Pubitemid 43902581)
58. Zhang SL, Yu Y, Roos J et al. (2005) STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane. Nature 437:902-5 (Pubitemid 41486767)