Chronic receptor-mediated activation of G i/o proteins alters basal t-tubular and sarcolemmal L-type Ca 2+ channel activity through phosphatases in heart failure

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 302, Issue 8, 2012, Pages

  Kashihara, Toshihide ^a   Nakada, Tsutomu ^a   Shimojo, Hisashi ^a   Horiuchi Hirose, Miwa ^a   Gomi, Simmon ^a   Shibazaki, Toshihide ^a,b   Sheng, Xiaona ^a,c   Hirose, Masamichi ^d   Hongo, Minoru ^e   Yamada, Mitsuhiko ^a  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Kissei Pharmaceutical Company Limited   (Japan)

^c SHINSHU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d IWATE MEDICAL UNIVERSITY   (Japan)

^e SHINSHU UNIVERSITY   (Japan)

Author keywords

Protein phosphatase 1; Protein phosphatase 2a; t tubule

Indexed keywords

CALCIUM CHANNEL L TYPE; FOSTRIECIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; ISOPRENALINE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; NIFEDIPINE; PERTUSSIS TOXIN; PHOSPHATASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DENSITY; CHANNEL GATING; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; HEART FAILURE; HEART LEFT VENTRICLE; HEART MUSCLE CELL; KIDNEY PROXIMAL TUBULE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SARCOLEMMA;

3-PYRIDINECARBOXYLIC ACID, 1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-(2-(TRIFLUOROMETHYL)PHENYL)-, METHYL ESTER; ADRENERGIC BETA-AGONISTS; ALGORITHMS; ANIMALS; BLOOD PRESSURE; CALCIUM CHANNEL AGONISTS; CALCIUM CHANNELS, L-TYPE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; HEART FAILURE; HEART RATE; ISOPROTERENOL; MALE; MEMBRANE POTENTIALS; MICE; MICE, INBRED C57BL; MICROTUBULES; MYOCARDIUM; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; PERTUSSIS TOXIN; PHOSPHOPROTEIN PHOSPHATASES; RECEPTORS, G-PROTEIN-COUPLED; SARCOLEMMA;

EID: 84859741029     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00589.2011     Document Type: Article

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