Enhanced calcium cycling and contractile function in transgenic hearts expressing constitutively active Gαo* protein

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 294, Issue 3, 2008, Pages

  Zhu, Ming ^a,b   Gach, Agnieszka A ^b   Liu, GongXin ^a,b   Xu, Xiaomei ^b   Chee, Chew Lim ^c   Zhang, Julie X ^b   Mao, Lan ^d   Chuprun, Kurt ^e   Koch, Walter J ^e   Liao, Ronglih ^b,c   Koren, Gideon ^a,b   Blaxall, Burns C ^f   Mende, Ulrike ^a,b,g  

^a BROWN UNIVERSITY   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

^e THOMAS JEFFERSON UNIVERSITY   (United States)

^f UNIVERSITY OF ROCHESTER   (United States)

^g RHODE ISLAND HOSPITAL   (United States)

Author keywords

Calcium; Contraction; G proteins; Signal transduction; Transgenic mice

Indexed keywords

BETA ADRENERGIC RECEPTOR; CALCIUM; CALCIUM CHANNEL L TYPE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; GUANINE NUCLEOTIDE BINDING PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; ISOPRENALINE; PHOSPHOLAMBAN; PHOSPHOPROTEIN PHOSPHATASE 1; RYANODINE RECEPTOR; SODIUM CALCIUM EXCHANGE PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CALCIUM SIGNALING; CELL STRUCTURE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HEART; HEART MUSCLE CELL; HEART VENTRICLE; HEART VENTRICLE CONTRACTILITY; HEART VENTRICLE CONTRACTION; IN VIVO STUDY; MOUSE; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RECEPTOR DENSITY; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ADENOVIRIDAE INFECTIONS; ADRENERGIC BETA-AGONISTS; ANIMALS; ANIMALS, GENETICALLY MODIFIED; BLOTTING, NORTHERN; BLOTTING, WESTERN; CALCIUM; CALCIUM CHANNELS, L-TYPE; CALCIUM SIGNALING; CELL SEPARATION; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYTOCHROMES C; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; ISOPROTERENOL; MICE; MICROFILAMENTS; MYOCARDIAL CONTRACTION; MYOCARDIUM; MYOCYTES, CARDIAC; RATS; RNA, MESSENGER; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SIGNAL TRANSDUCTION;

EID: 41549157712     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00584.2007     Document Type: Article

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