myo-inositol uptake is essential for bulk inositol phospholipid but not glycosylphosphatidylinositol synthesis in Trypanosoma brucei

Journal of Biological Chemistry

Volumn 287, Issue 16, 2012, Pages 13313-13323

  Gonzalez Salgado, Amaia ^a   Steinmann, Michael E ^a   Greganova, Eva ^b   Rauch, Monika ^a   Mäser, Pascal ^b   Sigel, Erwin ^a   Bütikofer, Peter ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

DE NOVO SYNTHESIS; DOMESTIC ANIMALS; DOWN-REGULATION; GLYCOSYLPHOSPHATIDYLINOSITOL; INOSITOL PHOSPHATE; MYO-INOSITOL; PARASITE-; PHOSPHATIDYLINOSITOL; RNA INTERFERENCE; SLEEPING SICKNESS; SYMPORTERS; SYMPORTS; TRYPANOSOMA BRUCEI;

AMIDES; CELL MEMBRANES; GLUCOSE; PHOSPHOLIPIDS; RNA;

ALCOHOLS;

CARRIER PROTEIN; GLYCOSYLPHOSPHATIDYLINOSITOL; INOSITOL; INOSITOL PHOSPHORYLCERAMIDE; INOSITOL TRANSPORTER; PHOSPHATIDYLINOSITIDE; RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; DOWN REGULATION; ENZYME SPECIFICITY; FLUOROGRAPHY; GENE SILENCING; GENETIC TRANSFECTION; GOLGI COMPLEX; LIPID ANALYSIS; LIPOGENESIS; NONHUMAN; OOCYTE; PARASITE SURVIVAL; PHYLOGENY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RNA INTERFERENCE; RNA ISOLATION; THIN LAYER CHROMATOGRAPHY; TRYPANOSOMA BRUCEI; XENOPUS LAEVIS;

ANIMALS; CARRIER PROTEINS; DOWN-REGULATION; GENES, PROTOZOAN; GLYCOSYLPHOSPHATIDYLINOSITOLS; INOSITOL; OOCYTES; PHENOTYPE; PHOSPHATIDYLINOSITOLS; PHYLOGENY; RNA INTERFERENCE; RNA, PROTOZOAN; TRITIUM; TRYPANOSOMA BRUCEI BRUCEI; XENOPUS;

ANIMALIA; EUKARYOTA; TRYPANOSOMA BRUCEI;

EID: 84859736494     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.344812     Document Type: Article

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