In vitro evidence for the brain glutamate efflux hypothesis: Brain endothelial cells cocultured with astrocytes display a polarized brain-to-blood transport of glutamate

GLIA

Volumn 60, Issue 6, 2012, Pages 882-893

  Helms, Hans Christian ^a   Madelung, Rasmus ^a   Waagepetersen, Helle Sønderby ^a   Nielsen, Carsten Uhd ^a   Brodin, Birger ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Blood brain barrier model; Central nervous system; Efflux; Endothelial glutamate; L glutamate pharmacology

Indexed keywords

ASPARTIC ACID; EXCITATORY AMINO ACID TRANSPORTER 1; GLUTAMIC ACID; MANNITOL; MESSENGER RNA;

ANIMAL CELL; ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; BRAIN CAPILLARY; BRAIN CELL; CELL ISOLATION; CELL METABOLISM; CELL TRANSPORT; COCULTURE; CONTROLLED STUDY; ENDOTHELIUM CELL; IMMUNOFLUORESCENCE; INTERSTITIAL FLUID; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AMINO ACIDS; ANIMALS; ASPARTIC ACID; ASTROCYTES; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; BRAIN; CATTLE; CELL POLARITY; CELLS, CULTURED; ELECTRIC IMPEDANCE; ENDOTHELIAL CELLS; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMATE PLASMA MEMBRANE TRANSPORT PROTEINS; GLUTAMIC ACID; MANNITOL; RATS; RNA, MESSENGER; SODIUM; TRITIUM;

EID: 84859734572     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.22321     Document Type: Article

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