YKL-40 Is Differentially Expressed in Human Embryonic Stem Cells and in Cell Progeny of the Three Germ Layers

Journal of Histochemistry and Cytochemistry

Volumn 60, Issue 3, 2012, Pages 188-204

  Brøchner, Christian B ^a   Johansen, Julia S ^b   Larsen, Lars A ^a   Bak, Mads ^a   Mikkelsen, Hanne B ^a   Byskov, Anne Grete ^c   Andersen, Claus Yding ^c   Møllgård, Kjeld ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^c Rigshospitalet   (Denmark)

Author keywords

cell differentiation; development; hESC; histomorphology; YKL 40

Indexed keywords

CD34 ANTIGEN; FIBROBLAST GROWTH FACTOR; GLYCOPROTEIN; HEPATOCYTE NUCLEAR FACTOR 3BETA; MESSENGER RNA; NESTIN; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN P63; PROTEIN YKL 40; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR PAX6; TRANSCRIPTION FACTOR PDX 1; UNCLASSIFIED DRUG; ADIPOCYTOKINE; BIOLOGICAL MARKER; CHI3L1 PROTEIN, HUMAN; LECTIN; OXYGEN;

ANIMAL CELL; ARTICLE; ATMOSPHERE; CELL CULTURE; CELL DIFFERENTIATION; CELL LINE; CELL LINEAGE; CULTURE MEDIUM; EMBRYO; EMBRYONIC STEM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIOID CELL; FEEDER CELL; FIBROBLAST; GERM LAYER; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; NONHUMAN; OXYGEN TENSION; PLURIPOTENT STEM CELL; PREPUCE; PRIORITY JOURNAL; PROGENY; PROTEIN EXPRESSION; PROTEIN SECRETION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN CELL; STAINING; ANIMAL; ANTIBODY SPECIFICITY; BIOSYNTHESIS; CELL HYPOXIA; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM;

ADIPOKINES; ANIMALS; BIOLOGICAL MARKERS; CELL DIFFERENTIATION; CELL HYPOXIA; CELL LINE; CELL PROLIFERATION; EMBRYONIC STEM CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEEDER CELLS; FIBROBLASTS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GERM LAYERS; HUMANS; LECTINS; MICE; ORGAN SPECIFICITY; OXYGEN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 84859640249     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1369/0022155411433331     Document Type: Article

References (49)

1. Adewumi O,Aflatoonian B,Ahrlund-Richter L,Amit M,Andrews PW,Beighton G,Bello PA,Benvenisty N,Berry LS,Bevan S, et al.Characterization of human embryonic stem cell lines by the International Stem Cell Initiative.Nat Biotechnol. 2007;25:803-816.
2. Awan A,Oliveri RS,Jensen PL,Christensen ST,Andersen CY.Immunoflourescence and mRNA analysis of human embryonic stem cells (hESCs) grown under feeder-free conditions.Methods Mol Biol. 2010;584:195-210.
3. Baeten D,Boots AM,Steenbakkers PG,Elewaut D,Bos E,Verheijden GF,Berheijden G,Miltenburg AM,Rijnders AW,Veys EM, et al.Human cartilage gp-39+,CD16+ monocytes in peripheral blood and synovium: correlation with joint destruction in rheumatoid arthritis.Arthritis Rheum. 2000;43:1233-1243.
4. Bigg HF,Wait R,Rowan AD,Cawston TE.The mammalian chitinase-like lectin, YKL-40, binds specifically to type I collagen and modulates the rate of type I collagen fibril formation.J Biol Chem. 2006;281:21082-21095.
5. Brøchner CB,Vestentoft PS,Lynnerup N,Andersen CY,Møllgård K.A two- and three-dimensional approach for visualizing human embryonic stem cell differentiation.Methods Mol Biol. 2010;584:179-193.
6. Bussink AP,Speijer D,Aerts JM,Boot RG.Evolution of mammalian chitinase(-like) members of family 18 glycosyl hydrolases.Genetics. 2007;177:959-970.
7. Chaffer CL,Weinberg RA.A perspective on cancer cell metastasis.Science. 2011;331:1559-1564.
8. Chupp GL,Lee CG,Jarjour N,Shim YM,Holm CT,He S,Dziura JD,Reed J,Coyle AJ,Kiener P, et al.A chitinase-like protein in the lung and circulation of patients with severe asthma.N Engl J Med. 2007;357:2016-2027.
9. Dickey BF.Exoskeletons and exhalation.N Engl J Med. 2007;357:2082-2084.
10. Eastham AM,Spencer H,Soncin F,Ritson S,Merry CL,Stern PL,Ward CM.Epithelial-mesenchymal transition events during human embryonic stem cell differentiation.Cancer Res. 2007;67:11254-11262.
11. Eiselleova L,Peterkova I,Neradil J,Slaninova I,Hampl A,Dvorak P.Comparative study of mouse and human feeder cells for human embryonic stem cells.Int J Dev Biol. 2008;52:353-363.
12. Ezashi T,Das P,Roberts RM.Low O2 tensions and the prevention of differentiation of hES cells.Proc Natl Acad Sci U S A. 2005;102:4783-4788.
13. Faibish M,Francescone RA,Bentley B,Yan W,Shao R.A YKL-40 neutralizing antibody blocks tumor angiogenesis and progression: a potential therapeutic agent in cancers.Mol Cancer Ther. 2011;10:742-751.
14. Forristal CE,Wright KL,Hanley NA,Oreffo RO,Houghton FD.Hypoxia inducible factors regulate pluripotency and proliferation in human embryonic stem cells cultured at reduced oxygen tensions.Reproduction. 2010;139:85-97.
15. Francescone RA,Scully S,Faibish M,Taylor SL,Oh D,Moral L,Yan W,Bentley B,Shao R.Role of YKL-40 in the angiogenesis, radioresistance, and progression of glioblastoma.J Biol Chem. 2011;286:15332-15343.
16. Fusetti F,Pijning T,Kalk KH,Bos E,Dijkstra BW.Crystal structure and carbohydrate-binding properties of the human cartilage glycoprotein-39.J Biol Chem. 2003;278:37753-37760.
17. Hakala BE,White C,Recklies AD.Human cartilage gp-39, a major secretory product of articular chondrocytes and synovial cells, is a mammalian member of a chitinase protein family.J Biol Chem. 1993;268:25803-25810.
18. Harvey S,Weisman M,O'Dell J,Scott T,Krusemeier M,Visor J,Swindlehurst C.Chondrex: new marker of joint disease.Clin Chem. 1998;44:509-516.
19. Hay ED.The mesenchymal cell, its role in the embryo, and the remarkable signaling mechanisms that create it.Dev Dyn. 2005;233:706-720.
20. Hough SR,Laslett AL,Grimmond SB,Kolle G,Pera MF.A continuum of cell states spans pluripotency and lineage commitment in human embryonic stem cells.PLoS One. 2009;4:e7708.
21. Houston DR,Recklies AD,Krupa JC,van Aalten DM.Structure and ligand-induced conformational change of the 39-kDa glycoprotein from human articular chondrocytes.J Biol Chem. 2003;278:30206-30212.
22. Itskovitz-Eldor J,Schuldiner M,Karsenti D,Eden A,Yanuka O,Amit M,Soreq H,Benvenisty N.Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers.Mol Med. 2000;6:88-95.
23. Jacobsen JV,Andersen CY,Hyttel P,Møllgård KEmbryonic stem cells: basic biology to bioengineering. Kallos MS, ed. Rijeka, Croatia: InTech; 2011:171-190.
24. Johansen JS.Studies on serum YKL-40 as a biomarker in diseases with inflammation, tissue remodelling, fibroses and cancer.Dan Med Bull. 2006;53:172-209.
25. Johansen JS,Høyer PE,Larsen LA,Price PA,Møllgård K.YKL-40 protein expression in the early developing human musculoskeletal system.J Histochem Cytochem. 2007;55:1213-1228.
26. Johansen JS,Schultz NA,Jensen BV.Plasma YKL-40: a potential new cancer biomarker?.Future Oncol. 2009;5:1065-1082.
27. Johansen JS,Williamson MK,Rice JS,Price PA.Identification of proteins secreted by human osteoblastic cells in culture.J Bone Miner Res. 1992;7:501-512.
28. Kalluri R,Weinberg RA.The basics of epithelial-mesenchymal transition.J Clin Invest. 2009;119:1420-1428.
29. Lang FF,Gumin J,Amano T,Hata N,Heimberger AB,Marini F,Andreeff M,Aldape KD.Tumor-derived mesenchymal stem cells in human gliomas: isolation and biological properties.J Clin Oncol. 2008;26 (Suppl).
30. Laursen SB,Møllgård K,Olesen C,Oliveri RS,Brøchner CB,Byskov AG,Andersen AN,Høyer PE,Tommerup N,Yding Andersen C.Regional differences in expression of specific markers for human embryonic stem cells.Reprod Biomed Online. 2007;15:89-98.
31. Lee CG,Da Silva CA,Dela Cruz CS,Ahangari F,Ma B,Kang MJ,He CH,Takyar S,Elias JA.Role of chitin and chitinase/chitinase-like proteins in inflammation, tissue remodeling, and injury.Annu Rev Physiol. 2011;73:479-501.
32. Ling H,Recklies AD.The chitinase 3-like protein human cartilage glycoprotein 39 inhibits cellular responses to the inflammatory cytokines interleukin-1 and tumour necrosis factor-alpha.Biochem J. 2004;380:651-659.
33. Liu Q,Nguyen DH,Dong Q,Shitaku P,Chung K,Liu OY,Tso JL,Liu JY,Konkankit V,Cloughesy TF, et al.Molecular properties of CD133+ glioblastoma stem cells derived from treatment-refractory recurrent brain tumors.J Neurooncol. 2009;94:1-19.
34. Lou N,Wang Y,Sun D,Zhao J,Wang Y,Gao Z.Isolation of stem-like cells from human MG-63 osteosarcoma cells using limiting dilution in combination with vincristine selection.Indian J Biochem Biophys. 2010;47:340-347.
35. Malinda KM,Ponce L,Kleinman HK,Shackelton LM,Millis AJ.Gp38k, a protein synthesized by vascular smooth muscle cells, stimulates directional migration of human umbilical vein endothelial cells.Exp Cell Res. 1999;250:168-173.
36. Millman JR,Tan JH,Colton CK.The effects of low oxygen on self-renewal and differentiation of embryonic stem cells.Curr Opin Organ Transplant. 2009;14:694-700.
37. Nishikawa KC,Millis AJ.gp38k (CHI3L1) is a novel adhesion and migration factor for vascular cells.Exp Cell Res. 2003;287:79-87.
38. Recklies AD,Ling H,White C,Bernier SM.Inflammatory cytokines induce production of CHI3L1 by articular chondrocytes.J Biol Chem. 2005;280:41213-41221.
39. Recklies AD,White C,Ling H.The chitinase 3-like protein human cartilage glycoprotein 39 (HC-gp39) stimulates proliferation of human connective-tissue cells and activates both extracellular signal-regulated kinase- and protein kinase B-mediated signalling pathways.Biochem J. 2002;365:119-126.
40. Rehli M,Krause SW,Andreesen R.Molecular characterization of the gene for human cartilage gp-39 (CHI3L1), a member of the chitinase protein family and marker for late stages of macrophage differentiation.Genomics. 1997;43:221-225.
41. Rehli M,Niller HH,Ammon C,Langmann S,Schwarzfischer L,Andreesen R,Krause SW.Transcriptional regulation of CHI3L1, a marker gene for late stages of macrophage differentiation.J Biol Chem. 2003;278:44058-44067.
42. Renkema GH,Boot RG,Au FL,Donker-Koopman WE,Strijland A,Muijsers AO,Hrebicek M,Aerts JM.Chitotriosidase, a chitinase, and the 39-kDa human cartilage glycoprotein, a chitin-binding lectin, are homologues of family 18 glycosyl hydrolases secreted by human macrophages.Eur J Biochem. 1998;251:504-509.
43. Reubinoff BE,Pera MF,Fong CY,Trounson A,Bongso A.Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro.Nat Biotechnol. 2000;18:399-404.
44. Saidi A,Javerzat S,Bellahcene A,De VJ,Bello L,Castronovo V,Deprez M,Loiseau H,Bikfalvi A,Hagedorn M.Experimental anti-angiogenesis causes upregulation of genes associated with poor survival in glioblastoma.Int J Cancer. 2008;122:2187-2198.
45. Schultz NA,Johansen JS.YKL-40-a protein in the field of translational medicine: a role as a biomarker in cancer patients?.Cancers. 2010;2:1453-1491.
46. Shackelton LM,Mann DM,Millis AJ.Identification of a 38-kDa heparin-binding glycoprotein (gp38k) in differentiating vascular smooth muscle cells as a member of a group of proteins associated with tissue remodeling.J Biol Chem. 1995;270:13076-13083.
47. Thiery JP,Acloque H,Huang RY,Nieto MA.Epithelial-mesenchymal transitions in development and disease.Cell. 2009;139:871-890.
48. Thomson JA,Itskovitz-Eldor J,Shapiro SS,Waknitz MA,Swiergiel JJ,Marshall VS,Jones JM.Embryonic stem cell lines derived from human blastocysts.Science. 1998;282:1145-1147.
49. Visvader JE.Cells of origin in cancer.Nature. 2011;469:314-322.