Chitotriosidase a chitinase, and the 39-kDa human cartilage glycoprotein, a chitin-binding lectin, are homologues of family 18 glycosyl hydrolases secreted by human macrophages

European Journal of Biochemistry

Volumn 251, Issue 1-2, 1998, Pages 504-509

  Renkema, G Herma ^a   Boot, Rolf G ^a   Au, Fung Lin ^a   Donker Koopman, Wilma E ^a   Strijland, Anneke ^a   Muijsers, Anton O ^a   Hrebicek, Martin ^b   Aerts, Johannes M F G ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b CHARLES UNIVERSITY   (Czech Republic)

Author keywords

Chitinase; Chitrotriosidase; Human cartilage glycoprotein of 39 kDa; Lectin; Macrophages

Indexed keywords

CHITIN; CHITINASE; CHITOTRIOSIDASE; GLYCOPROTEIN GP 39; GLYCOSIDASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CARTILAGE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELLS, CULTURED; CHITIN; COS CELLS; GLYCOPROTEINS; HEXOSAMINIDASES; HUMANS; MACROPHAGES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0032518453     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1998.2510504.x     Document Type: Article

References (46)

1. Watanabe, T., Suzuki, K., Oyanagi, W., Ohnishi, K. & Tanaka, H. (1990) Gene cloning of chitinase A1 from Bacillus circulans WL-12 revealed its evolutionary relationship to Serratia chitinase and to the type III homology units of fibronectin, J. Biol. Chem. 265, 15659-15665.
2. Watanabe, T., Oyanagi, W., Suzuki, K., Ohnishi, K. & Tanaka, H. (1992) Structure of the gene encoding chitinase D of Bacillus circulans WL-12 and possible homology of the enzyme to other prokaryotic chitinases and class III plant chitinases, J. Bacteriol. 174, 408-414.
3. Brurberg, M. B., Eijsink, V. C. H. & Nes, I. F. (1994) Characterization of a chitinase gene (chiA) from Serratia marcescens BJL200 and one-step purification of the gene product. FEMS Microbiol. Lett. 124, 399-404.
4. Hayes, C. K., Klemsdal, S., Lorito, M., Di Pietro, A., Peterbauer, C., Nakas, J. P., Tronsino, A. & Harman, G. E. (1994) Isolation and sequencing of an endochitinase-encoding gene from a cDNA library of Trichoderma harziamun, Gene (Amst.) 138, 143-148.
5. Blaiseau, P. & Lafay, J. (1992) Primary structure of a chitinase-encoding gene (chil) from the filamentous fungus Aphanocladium album: similarity to bacterial chitinases. Gene (Amst.) 120, 243-248.
6. Kuranda, M. J. & Robbins, P. W. (1991) Chitinase is required for cell separation during growth of Saccharomyces cerevisiae, J. Biol. Chem. 266, 19758-19767.
7. Kramer, K. J., Corpuz, L., Choi, H. K. & Mathukrishnan, S. (1993) Sequence of a cDNA and expression of the gene encoding epidermal and gut chitinases of Manduca sexta, Insect Biochem. Mol. Biol. 23, 691-701.
8. Fuhrman, J. A., Lane, W. S., Smith, R. R. Piessens, W. F. & Perler, F. B. (1992) Transmission-blocking antibodies recognize microfilarial chitinase in Brugian lymphatic filariasis. Proc. Natl Acad. Sci. USA 89, 1548-1552.
9. Krishnan, A., Nair, P. N. & Jones, D. (1994) Isolation, cloning, and characterization of a new chitinase stored in the active form in chitin-lined venom reservoir, J. Biol. Chem. 269, 20971-20976.
10. Jekel, P. A., Hartman, J. B. H. & Beintema, J. J. (1991) The primary structure of hevamine, an enzyme with lysozyme/chitinase activity from Hevea brasiliensis latex, Eur. J. Biochem. 200, 123-130.
11. Hollak, C. E. M., van Weely, S., van Oers, M. H. J. & Aerts, J. M. F. G. (1994) Marked elevation of plasma chitotriosidase activity, J. Clin. Invest. 93, 1288-1292.
12. Renkema, G. H., Boot, R. G., Muijsers, A. O., Donker-Koopman, W. E. & Aerts, J. M. F. G. (1995) Purification and characterization of human chitotriosidase, a novel member of the chitinase family of proteins. J. Biol Chem. 270, 2198-2202.
13. Boot, R. G., Renkema, G. H., Strijland, A., van Zonneveld, A. J. & Aerts, J. M. F. G. (1995) Cloning of a cDNA encoding chitotriosidase, a human chitinase produced by macrophages, J. Biol. Chem. 270, 26252-26256.
14. Renkema, G. H., Boot, R. G., Strijland, A., Donker-Koopman, W. E., van den Berg, M., Muijsers, A. O. & Aerts, J. M. F. G. (1997) Synthesis, sorting and processing into distinct isoforms of human macrophage chitotriosidase, Eur. J. Biochem. 244, 279-285.
15. Sahai, A. S. & Manocha, M. S. (1993) Chitinases of fungi and plants: their involvement in morphogenesis and host-parasite interaction, FEMS Microbiol. Rev. 11, 317-338.
16. Watanabe, T., Ito, Y., Yamada, T., Hashimoto, M., Sekine, S. & Tanaka, H. (1994) The roles of the C-terminal domain and type III domains of chitinase A1 from Bacillus circulans WL-12 in chitin degradation, J. Bacteriol. 176, 4465-4472.
17. Blaak, H. & Schrempf, H. (1995) Binding and substrate specificities of a Streptomyces olivaceoviridis chitinase in comparison with its proteolytic processed form, Eur. J. Biochem. 229, 132-139.
18. Broekaert, W. F., van Parijs, J., Leyns, F., Joos, H. & Peumans, W. J. (1989) A chitin-binding lectin from stinging nettle rhizomes with antifungal properties. Science 245, 1100-1102.
19. Hakala, B. E., White, C. & Recklies, A. D. (1993) Human cartilage gp-39, a major secretory product of articular chondrocytes and synovial cells, is a mammalian member of a chitinase protein family, J. Biol. Chem. 268, 25803-25810.
20. Johansen, J. S., Cintin, C., Jörgensen, M., Kamby, C. & Price, P. A. (1995) Serum YKL-40: a new potential marker of prognosis and location of metastases of patients with recurrent breast cancer, Eur. J. Cancer 31A, 1437-1442.
21. Hu, B., Trinh, K., Figueira, W. F. & Price, P. A. (1996) Isolation and sequence of a novel human chondrocyte protein related to mammalian members of the chitinase protein family, J. Biol. Chem. 271, 19415-19420.
22. Shackelton, L. M., Mann, D. M. & Millis, A. J. T. (1995) Identification of a 38-kDa heparin-binding glycoprotein (gp38k) in differentiating vascular smooth muscle cells as a marker of a group of proteins associated with tissue remodeling, J. Biol. Chem. 270, 13076-13083.
23. Morrison, B. W. & Leder, P. (1994) Neu and ras initiate murine mammary tumors that share genetic markers generally absent in c-myc and int-2-initiated tumors, Oncogene 9, 3417-3426.
24. Rejman, J. J. & Hurley, W. L. (1988) Isolation and characterization of a novel 39 kilodalton whey protein from bovine mammary secretions collected during the nonlactating period, Biochem. Biophys. Res. Commun. 150, 329-334.
25. Malette, B., Merlen, Y., Bleau, G. & Paquette, Y. (1995) Oviductins posses chitinase- and mucin-like domains: a lead in the search for the biological function of these oviduct-specific ZP-associating glycoproteins, Mol. Reprod. Dev. 41, 384-397.
26. Trudel, J. & Asselin, A. (1989) Detection of chitinase activity after polyacrylamide gel electrophoresis, Anal. Biochem. 178, 362-366.
27. Jonsson, L. M. V., Murray, G. J., Sorrel, S. H., Strijland, A., Aerts, J. M. F. G., Ginns, E. I., Barranger, J. A., Tager, J. M. & Schram, A. W. (1987) Biosynthesis and maturation of glucocerebrosidase in Gaucher fibroblasts, Eur. J. Biochem. 164, 171-179.
28. Laemmli, U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4, Nature 227, 680-685.
29. Lopata, M. A., Cleveland, D. W. & Sollner-Webb, B. (1984) High level transient expression of a chloramphenicol acetyl transferase by DEAE-dextran mediated DNA transfection coupled with dimethyl sulfoxide or glycerol shock treatment, Nucleic Acids Res. 12, 5707-5717.
30. Henrissat, B. (1990) Weak sequence homologies among chitinases detected by clustering analysis, Protein Seq. Data Anal. 3, 523-526.
31. Perrakis, A., Tews, I., Dauter, Z., Oppenheim, A. B., Chet, I., Wilson, K. S. & Vorgias, C. E. (1994) Crystal structure of a bacterial chitinase at 2.3 Ångstrom resolution. Structure 2, 1169-1180.
32. Terwisscha van Scheltinga, A. C., Hennig, M. & Dijkstra, B. W. (1996) The 1.8 A resolution structure of hevamine, a plant chitinase/lysozyme, and analysis of the conserved sequence and structure motifs of glycosyl hydrolase family 18, J. Mol. Biol. 262, 243-257.
33. Johansen, J. S., Williamson, M. K., Rice, J. S. & Price, P. A. (1992) Identification of proteins secreted by human osteoblastic cells in culture, J. Bone Miner. Res. 7, 501-512.
34. Nyirkos, P. & Golds, E. E. (1990) Human synovial cells secrete a 39 kDa protein similar to a bovine mammary protein expressed during the non-lactating period, Biochem. J. 268, 265-268.
35. Kirkpatrick, R. B., Matico, R. E., McNulty, D. E., Rosenberg, M. & Strickler, J. E. (1995) An abundantly secreted glycoprotein from Drosophila melanogaster is related to mammalian secretory proteins produced in rheumatoid tissues and by activated macrophages, Gene (Amst.) 153, 147-154.
36. Krause, S. W., Rehli, M., Kreutz, M., Schwarzfisher, L., Paulauski, J. D. & Andreesen, R. (1996) Differential screening identifies genetic markers of monocyte to macrophage maturation, J. Leukocyte. Biol. 60, 540-545.
37. Johansen, J. S., Jensen, H. S. & Price, P. A. (1993) A new biochemical marker for joint injury. Analysis of YKL-40 in serum and synovial fluid, Br. J. Rheumatol. 32, 949-955.
38. Watanabe, T., Kobori, K., Miyashita, K., Fujii, T., Sakai, H., Uchida, M. & Tanaka, H. (1993) Identification of glutamic acid 204 and aspartic acid 200 in chitinase A1 of Bacillus circulans WL-12 as essential residues for chitinase activity, J. Biol. Cliem. 268, 18567-18572.
39. Watanabe, T., Uchida, M., Kobori, K. & Tanaka, H. (1994) Site-directed mutagenesis of the Asp-197 and Asp-202 residues in chitinase A1 of Bacillus circulans WL-12, Biosci. Biotechnol. Biochem. 58, 2283-2285.
40. Schmidt, B. F., Ashizawa, E., Jarnagin, A. S., Lynn, S., Noto, G., Woodhouse, L., Estell, D. A. & Lad, P. (1994) Identification of two aspartates and a glutamate essential for the activity of endo-β-N-acetylglucosaminidase H from Streptomyces plicatus, Arch. Biochem. Biophys. 311, 350-353.
41. Gilkes, N. R., Henrissat, B., Kilburn, D. G., Miller, R. C. & Warren, R. A. J. (1991) Domains in microbial β-1,4-glycanases: sequence conservation, function, and enzyme families, Microbiol. Rev. 55, 303-315.
42. Venegas, A., Goldstein, J. C., Beauregard, K., Oles, A., Abdulhayoglu, N. & Fuhrman, J. A. (1996) Expression of recombinant microfilarial chitinase and analysis of domain function. Mol. Biochem. Parasitol. 78, 149-159.
43. Turner, M. W. (1996) Mannose-binding lectin: the pluripotent molecule of the innate immune system, Immunol. Today 17, 532-540.
44. Meyer, M. F. & Kreil, G. (1996) Cells expressing the DG42 gene from early Xenopus embryos synthesize hyaluronan, Proc. Natl Acad. Sci. USA 93, 4543-4547.
45. Laurent, T. C., Laurent, U. B. G. & Fraser, J. R. E. (1995) Functions of hyaluronan, Ann. Rheum. Dis. 54, 429-432.
46. Flach, J., Pilet, P.-E. & Jolles, P. (1992) What's new in chitinase research? Experientia 48, 701-716.