Understanding mechanisms of vitiligo development in Smyth line of chickens by transcriptomic microarray analysis of evolving autoimmune lesions

BMC Immunology

Volumn 13, Issue , 2012, Pages

  Shi, Fengying ^a   Kong, Byung Whi ^a   Song, Joon J ^a   Lee, Jeong Y ^a   Dienglewicz, Robert L ^a   Erf, Gisela F ^a  

^a UNIVERSITY OF ARKANSAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; TRANSCRIPTOME;

ADAPTIVE IMMUNITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOIMMUNE DISEASE; CELL DEATH; CHICKEN; CONTROLLED STUDY; DNA MICROARRAY; FEATHER; GENE EXPRESSION; GENETIC ANALYSIS; IMMUNE SYSTEM; INNATE IMMUNITY; MELANOCYTE; MICROARRAY ANALYSIS; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; SMYTH LINE; TRANSCRIPTOMICS; VITILIGO; ANIMAL; DISEASE MODEL; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORK; GENETICS; HUMAN; IMMUNOLOGY; REPRODUCIBILITY; SIGNAL TRANSDUCTION;

ANIMALS; AUTOIMMUNE DISEASES; CHICKENS; DISEASE MODELS, ANIMAL; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORKS; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REPRODUCIBILITY OF RESULTS; SIGNAL TRANSDUCTION; TRANSCRIPTOME; VITILIGO;

EID: 84859632804     PISSN: None     EISSN: 14712172     Source Type: Journal    
DOI: 10.1186/1471-2172-13-18     Document Type: Article

References (55)

1. Mattoo SK, Handa S, Kaur I, Gupta N, Malhotra R. Psychiatric morbidity in vitiligo: prevalence and correlates in India. J Eur Acad Dermatol Venereol 2002, 16:573-578. 10.1046/j.1468-3083.2002.00590.x, 12482039.
2. Taylor A, Pawaskar M, Taylor SL, Balkrishnan R, Feldman SR. Prevalence of pigmentary disorders and their impact on quality of life: a prospective cohort study. J Cosmet Dermatol 2008, 7:164-168. 10.1111/j.1473-2165.2008.00384.x, 18789050.
3. van den Boorn JG, Konijnenberg D, Dellemijn TA, van DV, Bos JD, Melief CJ, Vyth-Dreese FA, Luiten RM. Autoimmune destruction of skin melanocytes by perilesional T cells from vitiligo patients. J Invest Dermatol 2009, 129:2220-2232. 10.1038/jid.2009.32, 19242513.
4. Wick G, Andersson L, Hala K, Gershwin ME, Selmi C, Erf GF, Lamont SJ, Sgonc R. Avian models with spontaneous autoimmune diseases. Adv Immunol 2006, 92:71-117. 3292797, 17145302.
5. Erf GF. Animal model. Vitiligo 2010, 205-218. Heidelberg: Springer, Picardo M, Taieb A.
6. Shi F, Erf GF. IFN-gamma, IL-21 and IL-10 co-expression in evolving autoimmune vitiligo lesions of Smyth line chickens. J Invest Dermatol 2011, doi:10. 1038/jid.2011.377.
7. Boissy RE, Moellmann G, Trainer AT, Smyth JR, Lerner AB. Delayed-amelanotic (DAM or Smyth) chicken: melanocyte dysfunction in vivo and in vitro. J Invest Dermatol 1986, 86:149-156. 10.1111/1523-1747.ep12284190, 3091704.
8. Smyth JR. The Smyth chicken: a model for autoimmune amelanosis. Poultry biology 1989, 2:1-19.
9. Sreekumar GP, Smyth JR, Ambady S, Ponce de Leon FA. Analysis of the effect of endogenous viral genes in the Smyth line chicken model for autoimmune vitiligo. Am J Pathol 2000, 156:1099-1107. 10.1016/S0002-9440(10)64978-4, 1876847, 10702426.
10. Austin LM, Boissy RE, Jacobson BS, Smyth JR. The detection of melanocyte autoantibodies in the Smyth chicken model for vitiligo. Clin Immunol Immunopathol 1992, 64:112-120. 10.1016/0090-1229(92)90188-T, 1643744.
11. Austin LM, Boissy RE. Mammalian tyrosinase-related protein-1 is recognized by autoantibodies from vitiliginous Smyth chickens. An avian model for human vitiligo. Am J Pathol 1995, 146:1529-1541. 1870917, 7778691.
12. Searle EA, Austin LM, Boissy YL, Zhao H, Nordlund JJ, Boissy RE. Smyth chicken melanocyte autoantibodies: cross-species recognition, in vivo binding, and plasma membrane reactivity of the antiserum. Pigment Cell Res 1993, 6:145-157. 10.1111/j.1600-0749.1993.tb00594.x, 8234200.
13. Erf GF, Trejo-Skalli AV, Smyth JR. T cells in regenerating feathers of Smyth line chickens with vitiligo. Clin Immunol Immunopathol 1995, 76:120-126. 10.1006/clin.1995.1105, 7614730.
14. Shi F, Plumlee BL, Erf GF. Autoinflammatory/autoimmune vitiligo in Smyth line chickens: immune system- and melanocyte-related activities in feathers and in feather melanocytes isolated by laser capture microdissection [abstract]. Pigment Cell Melanoma Res 2009, 22:495.
15. Shresta S, Smyth JR, Erf GF. Profiles of pulp infiltrating lymphocytes at various times throughout feather regeneration in Smyth line chickens with vitiligo. Autoimmunity 1997, 25:193-201. 10.3109/08916939708994728, 9344327.
16. Wang X, Erf GF. Melanocyte-specific cell mediated immune response in vitiliginous Smyth line chickens. J Autoimmun 2003, 21:149-160. 10.1016/S0896-8411(03)00087-8, 12935784.
17. Wang X, Erf GF. Apoptosis in feathers of Smyth line chickens with autoimmune vitiligo. J Autoimmun 2004, 22:21-30. 10.1016/j.jaut.2003.09.006, 14709410.
18. Erf G, Wijesekera H, Lockhart B. Antioxidant capacity and oxidative stress in the local environment of feather-melanocytes in vitiliginous Smyth line chickens. Pigment Cell Res 2005, 18:69.
19. Erf GF, Bersi TK, Wang X, Sreekumar GP, Smyth JR. Herpesvirus connection in the expression of autoimmune vitiligo in Smyth line chickens. Pigment Cell Res 2001, 14:40-46. 10.1034/j.1600-0749.2001.140107.x, 11277493.
20. Spritz R. Shared genetic relationships underlying generalized vitiligo and autoimmune thyroid disease. Thyroid 2010, 20:745-754. 10.1089/thy.2010.1643, 2935342, 20578892.
21. Spritz R. Genetics. Vitiligo 2010, 155-163. Heidelberg: Springer, Picardo M, Taieb A.
22. Sreekumar GP, Smyth JR, Ponce de Leon FA. Molecular characterization of the Smyth chicken sublines and their parental controls by RFLP and DNA fingerprint analysis. Poult Sci 2001, 80:1-5.
23. Lee JY, Song JJ, Wooming A, Li X, Zhou H, Bottje WG, Kong BW. Transcriptional profiling of host gene expression in chicken embryo lung cells infected with laryngotracheitis virus. BMC Genomics 2010, 11:445. 10.1186/1471-2164-11-445, 3091642, 20663125.
24. Smyth GK. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol 2004, 3:Article 3.
25. Wong ML, Medrano JF. Real-time PCR for mRNA quantitation. Biotechniques 2005, 39:75-85. 10.2144/05391RV01, 16060372.
26. Yuen T, Wurmbach E, Pfeffer RL, Ebersole BJ, Sealfon SC. Accuracy and calibration of commercial oligonucleotide and custom cDNA microarrays. Nucleic Acids Res 2002, 30:e48. 10.1093/nar/30.10.e48, 115302, 12000853.
27. Abbas A, Lichtman A, Pillai S. Cellular and Molecular Immunology 2010, Philadelphia: Saunders Elsevier.
28. Boissy RE, Smyth JR, Fite KV. Progressive cytologic changes during the development of delayed feather amelanosis and associated choroidal defects in the DAM chicken line. A vitiligo model. Am J Pathol 1983, 111:197-212. 1916340, 6846502.
29. Kingo K, Aunin E, Karelson M, Philips MA, Ratsep R, Silm H, Vasar E, Soomets U, Koks S. Gene expression analysis of melanocortin system in vitiligo. J Dermatol Sci 2007, 48:113-122. 10.1016/j.jdermsci.2007.06.004, 17651944.
30. Kitamura R, Tsukamoto K, Harada K, Shimizu A, Shimada S, Kobayashi T, Imokawa G. Mechanisms underlying the dysfunction of melanocytes in vitiligo epidermis: role of SCF/KIT protein interactions and the downstream effector, MITF-M. J Pathol 2004, 202:463-475. 10.1002/path.1538, 15095274.
31. Jimbow K, Chen H, Park JS, Thomas PD. Increased sensitivity of melanocytes to oxidative stress and abnormal expression of tyrosinase-related protein in vitiligo. Br J Dermatol 2001, 144:55-65. 10.1046/j.1365-2133.2001.03952.x, 11167683.
32. Dell'Anna ML, Maresca V, Briganti S, Camera E, Falchi M, Picardo M. Mitochondrial impairment in peripheral blood mononuclear cells during the active phase of vitiligo. J Invest Dermatol 2001, 117:908-913. 10.1046/j.0022-202x.2001.01459.x, 11676831.
33. Koca R, Armutcu F, Altinyazar HC, Gurel A. Oxidant-antioxidant enzymes and lipid peroxidation in generalized vitiligo. Clin Exp Dermatol 2004, 29:406-409. 10.1111/j.1365-2230.2004.01524.x, 15245542.
34. Passi S, Grandinetti M, Maggio F, Stancato A, De LC. Epidermal oxidative stress in vitiligo. Pigment Cell Res 1998, 11:81-85. 10.1111/j.1600-0749.1998.tb00714.x, 9585244.
35. Yildirim M, Baysal V, Inaloz HS, Kesici D, Delibas N. The role of oxidants and antioxidants in generalized vitiligo. J Dermatol 2003, 30:104-108.
36. Kostovic K, Pastar Z, Pasic A, Ceovic R. Treatment of vitiligo with narrow-band UVB and topical gel containing catalase and superoxide dismutase. Acta Dermatovenerol Croat 2007, 15:10-14.
37. Dell'Anna ML, Mastrofrancesco A, Sala R, Venturini M, Ottaviani M, Vidolin AP, Leone G, Calzavara PG, Westerhof W, Picardo M. Antioxidants and narrow band-UVB in the treatment of vitiligo: a double-blind placebo controlled trial. Clin Exp Dermatol 2007, 32:631-636. 10.1111/j.1365-2230.2007.02514.x, 17953631.
38. Schallreuter KU, Moore J, Wood JM, Beazley WD, Gaze DC, Tobin DJ, Marshall HS, Panske A, Panzig E, Hibberts NA. In vivo and in vitro evidence for hydrogen peroxide (H2O2) accumulation in the epidermis of patients with vitiligo and its successful removal by a UVB-activated pseudocatalase. J Investig Dermatol Symp Proc 1999, 4:91-96. 10.1038/sj.jidsp.5640189, 10537016.
39. Yu L, Quinn MT, Cross AR, Dinauer MC. Gp91(phox) is the heme binding subunit of the superoxide-generating NADPH oxidase. Proc Natl Acad Sci USA 1998, 95:7993-7998. 10.1073/pnas.95.14.7993, 20917, 9653128.
40. Capasso M, Bhamrah MK, Henley T, Boyd RS, Langlais C, Cain K, Dinsdale D, Pulford K, Khan M, Musset B, et al. HVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen species. Nat Immunol 2010, 11:265-272. 10.1038/ni.1843, 3030552, 20139987.
41. Maly FE, Cross AR, Jones OT, Wolf-Vorbeck G, Walker C, Dahinden CA, De Weck AL. The superoxide generating system of B cell lines. Structural homology with the phagocytic oxidase and triggering via surface Ig. J Immunol 1988, 140:2334-2339.
42. Muller FL, Liu Y, Van RH. Complex III releases superoxide to both sides of the inner mitochondrial membrane. J Biol Chem 2004, 279:49064-49073. 10.1074/jbc.M407715200, 15317809.
43. Hann S-K, Taieb A, Gauthier Y, Benzekri L, Yu H-S, Lan C-CE, Wu C-S. Segmental vitiligo: a model to understand vitiligo?. vitiligo 2010, 295-310. Heidelberg: Springer, Picardo M, Taieb A.
44. Al'Abadie MS, Senior HJ, Bleehen SS, Gawkrodger DJ. Neuropeptide and neuronal marker studies in vitiligo. Br J Dermatol 1994, 131:160-165.
45. Liu PY, Bondesson L, Lontz W, Johansson O. The occurrence of cutaneous nerve endings and neuropeptides in vitiligo vulgaris: a case-control study. Arch Dermatol Res 1996, 288:670-675. 10.1007/BF02505276, 8931869.
46. Aroni K, Grapsa A, Lazaris AC, Kavantzas N, Kordosis T, Patsouris ES. Tissue estimation of protein gene product 9.5 (PGP 9.5) expression and apoptosis in vitiligo. Int J Dermatol 2008, 47:911-917. 10.1111/j.1365-4632.2008.03723.x, 18937653.
47. Cucchi ML, Frattini P, Santagostino G, Orecchia G. Higher plasma catecholamine and metabolite levels in the early phase of nonsegmental vitiligo. Pigment Cell Res 2000, 13:28-32. 10.1034/j.1600-0749.2000.130106.x, 10761993.
48. Cucchi ML, Frattini P, Santagostino G, Preda S, Orecchia G. Catecholamines increase in the urine of non-segmental vitiligo especially during its active phase. Pigment Cell Res 2003, 16:111-116. 10.1034/j.1600-0749.2003.00015.x, 12622787.
49. Morrone A, Picardo M, De LC, Terminali O, Passi S, Ippolito F. Catecholamines and vitiligo. Pigment Cell Res 1992, 5:65-69. 10.1111/j.1600-0749.1992.tb00003.x, 1321419.
50. Huang CL, Nordlund JJ, Boissy R. Vitiligo: a manifestation of apoptosis?. Am J Clin Dermatol 2002, 3:301-308. 10.2165/00128071-200203050-00001, 12069635.
51. Kingo K, Aunin E, Karelson M, Ratsep R, Silm H, Vasar E, Koks S. Expressional changes in the intracellular melanogenesis pathways and their possible role in the pathogenesis of vitiligo. J Dermatol Sci 2008, 52:39-46. 10.1016/j.jdermsci.2008.03.013, 18514490.
52. Ruiz-Arguelles A, Brito GJ, Reyes-Izquierdo P, Perez-Romano B, Sanchez-Sosa S. Apoptosis of melanocytes in vitiligo results from antibody penetration. J Autoimmun 2007, 29:281-286. 10.1016/j.jaut.2007.07.012, 17888626.
53. Hirobe T. Role of keratinocyte-derived factors involved in regulating the proliferation and differentiation of mammalian epidermal melanocytes. Pigment Cell Res 2005, 18:2-12. 10.1111/j.1600-0749.2004.00198.x, 15649147.
54. Wu CS, Yu CL, Wu CS, Lan CC, Yu HS. Narrow-band ultraviolet-B stimulates proliferation and migration of cultured melanocytes. Exp Dermatol 2004, 13:755-763. 10.1111/j.0906-6705.2004.00221.x, 15560759.
55. Lan CC, Chen GS, Chiou MH, Wu CS, Chang CH, Yu HS. FK506 promotes melanocyte and melanoblast growth and creates a favourable milieu for cell migration via keratinocytes: possible mechanisms of how tacrolimus ointment induces repigmentation in patients with vitiligo. Br J Dermatol 2005, 153:498-505. 10.1111/j.1365-2133.2005.06739.x, 16120133.