Up-regulation of uPARAP/Endo180 during culture activation of rat hepatic stellate cells and its presence in hepatic stellate cell lines from different species

BMC Cell Biology

Volumn 10, Issue , 2009, Pages

  Mousavi, Seyed A ^a,b   Fønhus, Marita S ^a   Berg, Trond ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PROTEIN ENDO 180; RECEPTOR PROTEIN; UNCLASSIFIED DRUG; UROKINASE RECEPTOR ASSOCIATED PROTEIN; COLLAGEN; ENDO180; LECTIN RECEPTOR; UROKINASE RECEPTOR;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CELL CULTURE; CELL ISOLATION; CELL LINE; CELL STRUCTURE; CELL TRANSDIFFERENTIATION; COLLAGEN DEGRADATION; CONTROLLED STUDY; ENDOCYTOSIS; GENE EXPRESSION; HUMAN; HUMAN CELL; ITO CELL; MALE; MYOFIBROBLAST; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; STELLATE CELL; UPREGULATION; WISTAR RAT; ANIMAL; GENETICS; METABOLISM;

RATTUS;

ANIMALS; CELL LINE; CELL TRANSDIFFERENTIATION; CELLS, CULTURED; COLLAGEN; HEPATIC STELLATE CELLS; HUMANS; RATS; RECEPTORS, MITOGEN; RECEPTORS, UROKINASE PLASMINOGEN ACTIVATOR; RNA, MESSENGER; UP-REGULATION;

EID: 66949168538     PISSN: None     EISSN: 14712121     Source Type: Journal    
DOI: 10.1186/1471-2121-10-39     Document Type: Article

References (59)

1. East L Isacke CM The mannose receptor family Biochimica et biophysica acta 2002, 1572(2-3):364-386 12223280
2. Llorca O Extended and bent conformations of the mannose receptor family Cell Mol Life Sci 2008 18193159
3. Sheikh H Yarwood H Ashworth A Isacke CM Endo180, an endocytic recycling glycoprotein related to the macrophage mannose receptor is expressed on fibroblasts, endothelial cells and macrophages and functions as a lectin receptor Journal of cell science 2000, 113(Pt 6):1021-1032 10683150
4. Isacke CM Geer van der P Hunter T Trowbridge IS p180, a novel recycling transmembrane glycoprotein with restricted cell type expression Mol Cell Biol 1990, 10(6):2606-2618 360619 2188094
5. Wu K Yuan J Lasky LA Characterization of a novel member of the macrophage mannose receptor type C lectin family The Journal of biological chemistry 1996, 271(35):21323-21330 10.1074/jbc.271.35.21323 8702911
6. Behrendt N Jensen ON Engelholm LH Mortz E Mann M Dano K A urokinase receptor-associated protein with specific collagen binding properties The Journal of biological chemistry 2000, 275(3):1993-2002 10.1074/ jbc.275.3.1993 10636902
7. East L McCarthy A Wienke D Sturge J Ashworth A Isacke CM A targeted deletion in the endocytic receptor gene Endo180 results in a defect in collagen uptake EMBO reports 2003, 4(7):710-716 1326321 12835757 10.1038/ sj.embor.embor882
8. Engelholm LH List K Netzel-Arnett S Cukierman E Mitola DJ Aaronson H Kjoller L Larsen JK Yamada KM Strickland DK et al uPARAP/Endo180 is essential for cellular uptake of collagen and promotes fibroblast collagen adhesion The Journal of cell biology 2003, 160(7):1009-1015 2172772 12668656 10.1083/jcb.200211091
9. Howard MJ Chambers MG Mason RM Isacke CM Distribution of Endo180 receptor and ligand in developing articular cartilage Osteoarthritis and cartilage/OARS, Osteoarthritis Research Society 2004, 12(1):74-82 10.1016/j.joca.2003.07.001 14697685
10. Howard MJ Isacke CM The C-type lectin receptor Endo180 displays internalization and recycling properties distinct from other members of the mannose receptor family The Journal of biological chemistry 2002, 277(35):32320-32331 10.1074/jbc.M203631200 12068012
11. Kjoller L Engelholm LH Hoyer-Hansen M Dano K Bugge TH Behrendt N uPARAP/ endo180 directs lysosomal delivery and degradation of collagen IV Experimental cell research 2004, 293(1):106-116 10.1016/ j.yexcr.2003.10.008 14729061
12. Madsen DH Engelholm LH Ingvarsen S Hillig T Wagenaar-Miller RA Kjoller L Gardsvoll H Hoyer-Hansen G Holmbeck K Bugge TH et al Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation The Journal of biological chemistry 2007, 282(37):27037-27045 10.1074/jbc.M701088200 17623673
13. Mousavi SA Sato M Sporstol M Smedsrod B Berg T Kojima N Senoo H Uptake of denatured collagen into hepatic stellate cells: Evidence for the involvement of urokinase plasminogen activator receptor-associated protein/Endo180 The Biochemical journal 2005, 387(Pt 1):39-46 1134930 15506989
14. Sturge J Wienke D Isacke CM Endosomes generate localized Rho-ROCK-MLC2-based contractile signals via Endo180 to promote adhesion disassembly The Journal of cell biology 2006, 175(2):337-347 2064574 17043135 10.1083/jcb.200602125
15. Wienke D MacFadyen JR Isacke CM Identification and characterization of the endocytic transmembrane glycoprotein Endo180 as a novel collagen receptor Molecular biology of the cell 2003, 14(9):3592-3604 196552 12972549 10.1091/mbc.E02-12-0814
16. Sturge J Wienke D East L Jones GE Isacke CM GPI-anchored uPAR requires Endo180 for rapid directional sensing during chemotaxis The Journal of cell biology 2003, 162(5):789-794 2172817 12952933 10.1083/jcb.200302124
17. Thomas EK Nakamura M Wienke D Isacke CM Pozzi A Liang P Endo180 binds to the C-terminal region of type I collagen The Journal of biological chemistry 2005, 280(24):22596-22605 10.1074/jbc.M501155200 15817460
18. Blomhoff R Green MH Berg T Norum KR Transport and storage of vitamin A Science (New York, NY) 1990, 250(4979):399-404
19. Geerts A History, heterogeneity, developmental biology, and functions of quiescent hepatic stellate cells Seminars in liver disease 2001, 21(3):311-335 10.1055/s-2001-17550 11586463
20. Wake K Perisinusoidal stellate cells (fat-storing cells, interstitial cells, lipocytes), their related structure in and around the liver sinusoids, and vitamin A-storing cells in extrahepatic organs International review of cytology 1980, 66:303-353 10.1016/ S0074-7696(08)61977-4 6993411
21. Friedman SL Liver fibrosis - from bench to bedside Journal of hepatology 2003, 38(Suppl 1):S38-53 10.1016/S0168-8278(02)00429-4 12591185
22. Czaja AJ Autoimmune liver disease Current opinion in gastroenterology 2003, 19(3):232-242 10.1097/00001574-200305000-00006 15703563
23. Haber PS Warner R Seth D Gorrell MD McCaughan GW Pathogenesis and management of alcoholic hepatitis Journal of gastroenterology and hepatology 2003, 18(12):1332-1344 10.1046/j.1440-1746.2003.03217.x
24. Rehermann B Nascimbeni M Immunology of hepatitis B virus and hepatitis C virus infection Nature reviews 2005, 5(3):215-229 10.1038/nri1573 15738952
25. Bataller R Brenner DA Liver fibrosis The Journal of clinical investigation 2005, 115(2):209-218 546435 15690074
26. Cassiman D Roskams T Beauty is in the eye of the beholder: Emerging concepts and pitfalls in hepatic stellate cell research Journal of hepatology 2002, 37(4):527-535 10.1016/S0168-8278(02)00263-5 12217608
27. Friedman SL Mechanisms of disease: Mechanisms of hepatic fibrosis and therapeutic implications Nature clinical practice 2004, 1(2):98-105 10.1038/ncpgasthep0055 16265071
28. Gressner AM Bachem MG Molecular mechanisms of liver fibrogenesis - a homage to the role of activated fat-storing cells Digestion 1995, 56(5):335-346 10.1159/000201257 8549875
29. Iredale JP Hepatic stellate cell behavior during resolution of liver injury Seminars in liver disease 2001, 21(3):427-436 10.1055/ s-2001-17557 11586470
30. Saile B Ramadori G Inflammation, damage repair and liver fibrosis - role of cytokines and different cell types Zeitschrift fur Gastroenterologie 2007, 45(1):77-86 10.1055/s-2006-927395 17236124
31. Friedman SL Roll FJ Isolation and culture of hepatic lipocytes, Kupffer cells, and sinusoidal endothelial cells by density gradient centrifugation with Stractan Analytical biochemistry 1987, 161(1):207-218 10.1016/0003-2697(87)90673-7 3578783
32. Herrmann J Gressner AM Weiskirchen R Immortal hepatic stellate cell lines: Useful tools to study hepatic stellate cell biology and function? Journal of cellular and molecular medicine 2007, 11(4):704-722 10.1111/ j.1582-4934.2007.00060.x
33. Wake K Sato T Intralobular heterogeneity of perisinusoidal stellate cells in porcine liver Cell and tissue research 1993, 273(2):227-237 10.1007/BF00312824
34. Ogawa K Suzuki J Mukai H Mori M Sequential changes of extracellular matrix and proliferation of Ito cells with enhanced expression of desmin and actin in focal hepatic injury The American journal of pathology 1986, 125(3):611-619 1888465 3799820
35. Yokoi Y Namihisa T Kuroda H Komatsu I Miyazaki A Watanabe S Usui K Immunocytochemical detection of desmin in fat-storing cells (Ito cells) Hepatology (Baltimore, Md) 1984, 4(4):709-714 10.1002/hep.1840040425 6204917
36. Gard AL White FP Dutton GR Extra-neural glial fibrillary acidic protein (GFAP) immunoreactivity in perisinusoidal stellate cells of rat liver Journal of neuroimmunology 1985, 8(4-6):359-375 10.1016/ S0165-5728(85)80073-4 3891783
37. Neubauer K Knittel T Aurisch S Fellmer P Ramadori G Glial fibrillary acidic protein - a cell type specific marker for Ito cells in vivo and in vitro Journal of hepatology 1996, 24(6):719-730 10.1016/ S0168-8278(96)80269-8 8835748
38. Buniatian GH Stages of activation of hepatic stellate cells: Effects of ellagic acid, an inhibiter of liver fibrosis, on their differentiation in culture Cell proliferation 2003, 36(6):307-319 10.1046/ j.1365-2184.2003.00287.x 14710849
39. Knittel T Aurisch S Neubauer K Eichhorst S Ramadori G Cell-type-specific expression of neural cell adhesion molecule (N-CAM) in Ito cells of rat liver. Up-regulation during in vitro activation and in hepatic tissue repair The American journal of pathology 1996, 149(2):449-462 1865318 8701984
40. Niki T De Bleser PJ Xu G Berg Van Den K Wisse E Geerts A Comparison of glial fibrillary acidic protein and desmin staining in normal and CCl4-induced fibrotic rat livers Hepatology (Baltimore, Md 1996, 23(6):1538-1545 10.1002/hep.510230634 8675175
41. Reynaert H Rombouts K Jia Y Urbain D Chatterjee N Uyama N Geerts A Somatostatin at nanomolar concentration reduces collagen I and III synthesis by, but not proliferation of activated rat hepatic stellate cells British journal of pharmacology 2005, 146(1):77-88 1576247 15980876 10.1038/sj.bjp.0706298
42. Ramadori G Veit T Schwogler S Dienes HP Knittel T Rieder H Meyer zum Buschenfelde KH Expression of the gene of the alpha-smooth muscle-actin isoform in rat liver and in rat fat-storing (ITO) cells Virchows Archiv 1990, 59(6):349-357 1705733
43. Rockey DC Boyles JK Gabbiani G Friedman SL Rat hepatic lipocytes express smooth muscle actin upon activation in vivo and in culture Journal of submicroscopic cytology and pathology 1992, 24(2):193-203
44. Mousavi SA Kjeken R Berg TO Seglen PO Berg T Brech A Effects of inhibitors of the vacuolar proton pump on hepatic heterophagy and autophagy Biochimica et biophysica acta 2001, 1510(1-2):243-257 10.1016/ S0005-2736(00)00354-0 11342162
45. Matrisian LM The matrix-degrading metalloproteinases Bioessays 1992, 14(7):455-463 10.1002/bies.950140705 1445287
46. Vogel WF Collagen-receptor signaling in health and disease Eur J Dermatol 2001, 11(6):506-514 11701397
47. Engelholm LH Nielsen BS Netzel-Arnett S Solberg H Chen XD Lopez Garcia JM Lopez-Otin C Young MF Birkedal-Hansen H Dano K et al The urokinase plasminogen activator receptor-associated protein/endo180 is coexpressed with its interaction partners urokinase plasminogen activator receptor and matrix metalloprotease-13 during osteogenesis Laboratory investigation; a journal of technical methods and pathology 2001, 81(10):1403-1414 11598153
48. Wagenaar-Miller RA Engelholm LH Gavard J Yamada SS Gutkind JS Behrendt N Bugge TH Holmbeck K Complementary roles of intracellular and pericellular collagen degradation pathways in vivo Molecular and cellular biology 2007, 27(18):6309-6322 10.1128/MCB.00291-07
49. Honardoust HA Jiang G Koivisto L Wienke D Isacke CM Larjava H Hakkinen L Expression of Endo180 is spatially and temporally regulated during wound healing Histopathology 2006, 49(6):634-648 10.1111/ j.1365-2559.2006.02559.x 17163848
50. Wienke D Davies GC Johnson DA Sturge J Lambros MB Savage K Elsheikh SE Green AR Ellis IO Robertson D et al The collagen receptor Endo180 (CD280) Is expressed on basal-like breast tumour cells and promotes tumour growth in vivo Cancer research 2007, 67(21):10230-10240 10.1158/ 0008-5472.CAN-06-3496 17974964
51. Curino AC Engelholm LH Yamada SS Holmbeck K Lund LR Molinolo AA Behrendt N Nielsen BS Bugge TH Intracellular collagen degradation mediated by uPARAP/Endo180 is a major pathway of extracellular matrix turnover during malignancy The Journal of cell biology 2005, 169(6):977-985 2171632 15967816 10.1083/jcb.200411153
52. Schnack Nielsen B Rank F Engelholm LH Holm A Dano K Behrendt N Urokinase receptor-associated protein (uPARAP) is expressed in connection with malignant as well as benign lesions of the human breast and occurs in specific populations of stromal cells International journal of cancer 2002, 98(5):656-664 10.1002/ijc.10227
53. Sulek J Wagenaar-Miller RA Shireman J Molinolo A Madsen DH Engelholm LH Behrendt N Bugge TH Increased expression of the collagen internalization receptor uPARAP/Endo180 in the stroma of head and neck cancer J Histochem Cytochem 2007, 55(4):347-353 10.1369/jhc.6A7133.2006 17189524
54. Enzan H Himeno H Iwamura S Onishi S Saibara T Yamamoto Y Hara H Alpha-smooth muscle actin-positive perisinusoidal stromal cells in human hepatocellular carcinoma Hepatology (Baltimore, Md) 1994, 19(4):895-903 8138263
55. Johnson SJ Burr AW Toole K Dack CL Mathew J Burt AD Macrophage and hepatic stellate cell responses during experimental hepatocarcinogenesis Journal of gastroenterology and hepatology 1998, 13(20):145-151 10.1111/ j.1440-1746.1998.tb00629.x
56. Terada T Makimoto K Terayama N Suzuki Y Nakanuma Y Alpha-smooth muscle actin-positive stromal cells in cholangiocarcinomas, hepatocellular carcinomas and metastatic liver carcinomas Journal of hepatology 1996, 24(6):706-712 10.1016/S0168-8278(96)80267-4 8835746
57. Weiskirchen R Gressner AM Isolation and culture of hepatic stellate cells Methods in molecular medicine 2005, 117:99-113 16118448
58. Pittman RC Carew TE Glass CK Green SR Taylor CA Jr Attie AD A radioiodinated, intracellularly trapped ligand for determining the sites of plasma protein degradation in vivo The Biochemical journal 1983, 212(3):791-800 1153156 6882394
59. Mousavi SA Sporstol M Fladeby C Kjeken R Barois N Berg T Receptor-mediated endocytosis of immune complexes in rat liver sinusoidal endothelial cells is mediated by FcgammaRIIb2 Hepatology (Baltimore, Md) 2007, 46(3):871-884 10.1002/hep.21748 17680646