A metabonomic study of biochemical changes characteristic of genetically hypertensive rats based on 1H NMR spectroscopic urinalysis

Hypertension Research

Volumn 35, Issue 4, 2012, Pages 404-412

  Akira, Kazuki ^a   Masu, Shigenori ^b   Imachi, Misako ^c   Mitome, Hidemichi ^a   Hashimoto, Takao ^d  

^a MATSUYAMA UNIVERSITY   (Japan)

^b JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c Bruker Corporation   (United States)

^d TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

metabonomics; NMR; SHR; urine

Indexed keywords

2 OXOGLUTARIC ACID; CITRIC ACID; CREATININE; DICARBOXYLIC ACID; GLUCURONIDE; GLYCINE DERIVATIVE; HIPPURIC ACID; SUCCINIC ACID; TAURINE;

AGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; HYPERTENSION; MALE; METABOLIC ACIDOSIS; METABOLISM; METABOLITE; NONHUMAN; PRINCIPAL COMPONENT ANALYSIS; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; URINALYSIS; URINARY EXCRETION; WISTAR KYOTO RAT;

ANIMALS; CITRIC ACID; CREATINE; DISEASE PROGRESSION; HIPPURATES; HYPERTENSION; MAGNETIC RESONANCE SPECTROSCOPY; METABOLOMICS; RATS; RATS, INBRED SHR; RATS, WISTAR; SUCCINIC ACID; TAURINE; URINALYSIS;

EID: 84859597915     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1038/hr.2011.182     Document Type: Article

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