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Volumn 18, Issue 4, 2012, Pages 500-501

Revelations into resveratrol's mechanism

Author keywords

[No Author keywords available]

Indexed keywords

NITRIC OXIDE; PHOSPHODIESTERASE; RESVERATROL; ROLIPRAM; SIRTUIN 1;

EID: 84859586430     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2727     Document Type: Note
Times cited : (15)

References (10)
  • 1
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    • Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases
    • Park, S.J. et al. Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases. Cell 148, 421-433 (2012).
    • (2012) Cell , vol.148 , pp. 421-433
    • Park, S.J.1
  • 2
    • 0141719702 scopus 로고    scopus 로고
    • Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
    • Howitz, K.T. et al. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 425, 191-196 (2003).
    • (2003) Nature , vol.425 , pp. 191-196
    • Howitz, K.T.1
  • 3
    • 20444431507 scopus 로고    scopus 로고
    • Substrate-specific activation of sirtuins by resveratrol
    • Kaeberlein, M. et al. Substrate-specific activation of sirtuins by resveratrol. J. Biol. Chem. 280, 17038-17045 (2005).
    • (2005) J. Biol. Chem. , vol.280 , pp. 17038-17045
    • Kaeberlein, M.1
  • 4
    • 77958488312 scopus 로고    scopus 로고
    • SIRT1 activation by small molecules: Kinetic and biophysical evidence for direct interaction of enzyme and activator
    • Dai, H. et al. SIRT1 activation by small molecules: kinetic and biophysical evidence for direct interaction of enzyme and activator. J. Biol. Chem. 285, 32695-32703 (2010).
    • (2010) J. Biol. Chem. , vol.285 , pp. 32695-32703
    • Dai, H.1
  • 5
    • 34249846128 scopus 로고    scopus 로고
    • Resveratrol stimulates AMP kinase activity in neurons
    • Dasgupta, B. & Milbrandt, J. Resveratrol stimulates AMP kinase activity in neurons. Proc. Natl. Acad. Sci. USA 104, 7217-7222 (2007).
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 7217-7222
    • Dasgupta, B.1    Milbrandt, J.2
  • 6
    • 0037167677 scopus 로고    scopus 로고
    • Resveratrol, a polyphenolic phytoalexin present in red wine, enhances expression and activity of endothelial nitric oxide synthase
    • Wallerath, T. et al. Resveratrol, a polyphenolic phytoalexin present in red wine, enhances expression and activity of endothelial nitric oxide synthase. Circulation 106, 1652-1658 (2002).
    • (2002) Circulation , vol.106 , pp. 1652-1658
    • Wallerath, T.1
  • 7
    • 0038309561 scopus 로고    scopus 로고
    • Resveratrol activates adenylyl-cyclase in human breast cancer cells: A novel, estrogen receptor-independent cytostatic mechanism
    • El-Mowafy, A.M. & Alkhalaf, M. Resveratrol activates adenylyl-cyclase in human breast cancer cells: a novel, estrogen receptor-independent cytostatic mechanism. Carcinogenesis 24, 869-873 (2003).
    • (2003) Carcinogenesis , vol.24 , pp. 869-873
    • El-Mowafy, A.M.1    Alkhalaf, M.2
  • 8
    • 20444444649 scopus 로고    scopus 로고
    • Mechanism of human SIRT1 activation by resveratrol
    • Borra, M.T., Smith, B.C. & Denu, J.M. Mechanism of human SIRT1 activation by resveratrol. J. Biol. Chem. 280, 17187-17195 (2005).
    • (2005) J. Biol. Chem. , vol.280 , pp. 17187-17195
    • Borra, M.T.1    Smith, B.C.2    Denu, J.M.3
  • 9
    • 35349011726 scopus 로고    scopus 로고
    • Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity
    • Kim, E.J., Kho, J.H., Kang, M.R. & Um, S.J. Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity. Mol. Cell 28, 277-290 (2007).
    • (2007) Mol. Cell , vol.28 , pp. 277-290
    • Kim, E.J.1    Kho, J.H.2    Kang, M.R.3    Um, S.J.4
  • 10
    • 36749087548 scopus 로고    scopus 로고
    • Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes
    • Milne, J.C. et al. Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes. Nature 450, 712-716 (2007).
    • (2007) Nature , vol.450 , pp. 712-716
    • Milne, J.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.