Induction of an osteoarthritis-like phenotype and degradation of phosphorylated Smad3 by Smurf2 in transgenic mice

Arthritis and Rheumatism

Volumn 58, Issue 10, 2008, Pages 3132-3144

  Wu, Qiuqian ^a   Kim, Kyung Ok ^a   Sampson, Erik R ^a   Chen, Di ^a   Awad, Hani ^a   O'Brien, Todd ^a   Puzas, J Edward ^a   Drissi, Hicham ^a   Schwarz, Edward M ^a   O'Keefe, Regis J ^a   Zuscik, Michael J ^a   Rosier, Randy N ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 10; COLLAGENASE 3; SMAD3 PROTEIN; SMURF2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; COMPUTER ASSISTED TOMOGRAPHY; GENOTYPE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; KNEE; KNEE ARTHROPLASTY; MORPHOMETRICS; MOUSE; NONHUMAN; OSTEOARTHRITIS; OSTEOPHYTE; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SAMPLING; TRANSGENIC MOUSE; UBIQUITINATION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; CELLS, CULTURED; CHONDROCYTES; DISEASE MODELS, ANIMAL; HUMANS; MICE; MICE, TRANSGENIC; OSTEOARTHRITIS, KNEE; SMAD3 PROTEIN; UBIQUITIN-PROTEIN LIGASES; UP-REGULATION;

EID: 54949147630     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.23946     Document Type: Article

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