K v7 (KCNQ) channel openers normalize central 2-deoxyglucose uptake in a mouse model of mania and increase prefrontal cortical and hippocampal serine-9 phosphorylation levels of GSK3β

Journal of Neurochemistry

Volumn 121, Issue 3, 2012, Pages 373-382

  Kristensen, Line V ^a   Sandager Nielsen, Karin ^a   Hansen, Henrik H ^a  

^a NEUROSEARCH A S   (Denmark)

Author keywords

2 deoxyglucose; bipolar disease; GSK3beta; KCNQ channel; mania; retigabine

Indexed keywords

CHLORDIAZEPOXIDE; DEOXYGLUCOSE; DEXAMPHETAMINE; GLYCOGEN SYNTHASE KINASE 3BETA; ICA 27243; LITHIUM CHLORIDE; PHOSPHOSERINE; POTASSIUM CHANNEL; POTASSIUM CHANNEL KV7; POTASSIUM CHANNEL KV7.2; POTASSIUM CHANNEL KV7.3; POTASSIUM CHANNEL STIMULATING AGENT; RETIGABINE; UNCLASSIFIED DRUG; VALPROIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN METABOLISM; CHANNEL GATING; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORPUS STRIATUM; DRUG DOSE COMPARISON; FOREBRAIN; GLUCOSE METABOLISM; HEXOSE TRANSPORT; HIPPOCAMPUS; MALE; MANIA; MOUSE; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; THALAMUS;

ANIMALS; ANTIMANIC AGENTS; AUTORADIOGRAPHY; BENZAMIDES; BIPOLAR DISORDER; CARBAMATES; CENTRAL NERVOUS SYSTEM STIMULANTS; CHLORDIAZEPOXIDE; DEOXYGLUCOSE; DEXTROAMPHETAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GLYCOGEN SYNTHASE KINASE 3; HIPPOCAMPUS; HYPNOTICS AND SEDATIVES; KCNQ POTASSIUM CHANNELS; MALE; MICE; MICE, INBRED C57BL; PHENYLENEDIAMINES; PHOSPHORYLATION; PREFRONTAL CORTEX; PYRIDINES; SERINE;

EID: 84859576647     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2012.07704.x     Document Type: Article

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