Mtss1 regulates epidermal growth factor signaling in head and neck squamous carcinoma cells

Oncogene

Volumn 31, Issue 14, 2012, Pages 1781-1793

  Dawson, J C ^a   Timpson, P ^a   Kalna, G ^a   Machesky, L M ^a  

^a BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

Author keywords

epidermal growth factor receptor; HNSCC; Mtss1

Indexed keywords

COLLAGEN; EPIDERMAL GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MTSS1 PROTEIN; ONCOPROTEIN; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER MORPHOLOGY; CELL DENSITY; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; GENE FUNCTION; GENE LOSS; GENETIC REGULATION; HEAD AND NECK CARCINOMA; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; HUMAN CELL; METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA;

ANIMALS; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; EPIDERMAL GROWTH FACTOR; HEAD AND NECK NEOPLASMS; HUMANS; MICE; MICE, NUDE; MICROFILAMENT PROTEINS; NEOPLASM PROTEINS; NEOPLASM TRANSPLANTATION; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION;

EID: 84859571899     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.376     Document Type: Article

References (44)

1. Basu D, Nguyen TT, Montone KT, Zhang G, Wang LP, Diehl JA et al. (2010). Evidence for mesenchymal-like sub-populations within squamous cell carcinomas possessing chemoresistance and phenotypic plasticity. Oncogene 29: 4170-4182.
2. Bershteyn M, Atwood SX, Woo WM, Li M, Oro AE. (2010). MIM and cortactin antagonism regulates ciliogenesis and hedgehog signaling. Dev Cell 19: 270-283.
3. Betson M, Lozano E, Zhang J, Braga VM. (2002). Rac activation upon cell-cell contact formation is dependent on signaling from the epidermal growth factor receptor. J Biol Chem 277: 36962-36969.
4. Boissan M, De Wever O, Lizarraga F, Wendum D, Poincloux R, Chignard N et al. (2010). Implication of metastasis suppressor NM23-H1 in maintaining adherens junctions and limiting the invasive potential of human cancer cells. Cancer Res 70: 7710-7722.
5. Bompard G, Sharp SJ, Freiss G, Machesky LM. (2005). Involvement of Rac in actin cytoskeleton rearrangements induced by MIM-B. J Cell Sci 118: 5393-5403. (Pubitemid 41819600)
6. Bremm A, Walch A, Fuchs M, Mages J, Duyster J, Keller G et al. (2008). Enhanced activation of epidermal growth factor receptor caused by tumor-derived E-cadherin mutations. Cancer Res 68: 707-714. (Pubitemid 351206746)
7. Callahan CA, Ofstad T, Horng L, Wang JK, Zhen HH, Coulombe PA et al. (2004). MIM/BEG4, a Sonic hedgehog-responsive gene that potentiates Gli-dependent transcription. Genes Dev 18: 2724-2729. (Pubitemid 39507765)
8. Canel M, Secades P, Rodrigo JP, Cabanillas R, Herrero A, Suarez C et al. (2006). Overexpression of focal adhesion kinase in head and neck squamous cell carcinoma is independent of fak gene copy number. Clin Cancer Res 12: 3272-3279.
9. Cheng GZ, Chan J, Wang Q, Zhang W, Sun CD, Wang LH. (2007). Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel. Cancer Res 67: 1979-1987. (Pubitemid 46424214)
10. Chung CH, Ely K, McGavran L, Varella-Garcia M, Parker J, Parker N et al. (2006). Increased epidermal growth factor receptor gene copy number is associated with poor prognosis in head and neck squamous cell carcinomas. J Clin Oncol 24: 4170-4176. (Pubitemid 46622295)
11. Cooper JB, Cohen EE. (2009). Mechanisms of resistance to EGFR inhibitors in head and neck cancer. Head Neck 31: 1086-1094.
12. Danglot L, Chaineau M, Dahan M, Gendron MC, Boggetto N, Perez F et al. (2010). Role of TI-VAMP and CD82 in EGFR cell-surface dynamics and signaling. J Cell Sci 123: 723-735.
13. Donev IS, Wang W, Yamada T, Li Q, Takeuchi S, Matsumoto K et al. (2011). Transient PI3K inhibition induces apoptosis and overcomes HGF-mediated resistance to EGFR-TKIs in EGFR mutant lung cancer. Clin Cancer Res 17: 2260-2269.
14. Edward M, Gillan C, Micha D, Tammi RH. (2005). Tumour regulation of fibroblast hyaluronan expression: a mechanism to facilitate tumour growth and invasion. Carcinogenesis 26: 1215-1223. (Pubitemid 41417898)
15. Gan Y, Shi C, Inge L, Hibner M, Balducci J, Huang Y. (2010). Differential roles of ERK and Akt pathways in regulation of EGFR-mediated signaling and motility in prostate cancer cells. Oncogene 29: 4947-4958.
16. Goh LK, Huang F, Kim W, Gygi S, Sorkin A. (2010). Multiple mechanisms collectively regulate clathrin-mediated endocytosis of the epidermal growth factor receptor. J Cell Biol 189: 871-883.
17. Gonzalez-Quevedo R, Shoffer M, Horng L, Oro AE. (2005). Receptor tyrosine phosphatase-dependent cytoskeletal remodeling by the hedgehog-responsive gene MIM/BEG4. J Cell Biol 168: 453-463. (Pubitemid 40205067)
18. Hsia DA, Mitra SK, Hauck CR, Streblow DN, Nelson JA, Ilic D et al. (2003). Differential regulation of cell motility and invasion by FAK. J Cell Biol 160: 753-767. (Pubitemid 36298270)
19. Irie HY, Pearline RV, Grueneberg D, Hsia M, Ravichandran P, Kothari N et al. (2005). Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial-mesenchymal transition. J Cell Biol 171: 1023-1034. (Pubitemid 41815834)
20. Kelley LC, Shahab S, Weed SA. (2008). Actin cytoskeletal mediators of motility and invasion amplified and overexpressed in head and neck cancer. Clin Exp Metast 25: 289-304.
21. Lee SH, Kerff F, Chereau D, Ferron F, Klug A, Dominguez R. (2007). Structural basis for the actin-binding function of missing-inmetastasis. Structure 15: 145-155. (Pubitemid 46209813)
22. Lee YG, Macoska JA, Korenchuk S, Pienta KJ. (2002). MIM, a potential metastasis suppressor gene in bladder cancer. Neoplasia 4: 291-294. (Pubitemid 34755838)
23. Lin J, Liu J, Wang Y, Zhu J, Zhou K, Smith N et al. (2005). Differential regulation of cortactin and N-WASP-mediated actin polymerization by missing in metastasis (MIM) protein. Oncogene 24: 2059-2066. (Pubitemid 40516199)
24. Lin M, Smith LT, Smiraglia DJ, Kazhiyur-Mannar R, Lang JC, Schuller DE et al. (2006). DNA copy number gains in head and neck squamous cell carcinoma. Oncogene 25: 1424-1433. (Pubitemid 43336472)
25. Liu K, Wang G, Ding H, Chen Y, Yu G, Wang J. (2010). Downregulation of metastasis suppressor 1(MTSS1) is associated with nodal metastasis and poor outcome in Chinese patients with gastric cancer. BMC Cancer 10: 428.
26. Loberg RD, Neeley CK, Adam-Day LL, Fridman Y, St John LN, Nixdorf S et al. (2005). Differential expression analysis of MIM (MTSS1) splice variants and a functional role of MIM in prostate cancer cell biology. Int J Oncol 26: 1699-1705.
27. Ma S, Guan XY, Lee TK, Chan KW. (2007). Clinicopathological significance of missing in metastasis B expression in hepatocellular carcinoma. Hum Pathol 38: 1201-1206. (Pubitemid 47058158)
28. Machesky LM, Johnston SA. (2007). MIM: a multifunctional scaffold protein. J Mol Med 85: 569-576. (Pubitemid 46870900)
29. Mattila PK, Pykalainen A, Saarikangas J, Paavilainen VO, Vihinen H, Jokitalo E et al. (2007). Missing-in-metastasis and IRSp53 deform PI(4,5)P2-rich membranes by an inverse BAR domain-like mechanism. J Cell Biol 176: 953-964. (Pubitemid 46506969)
30. Mattila PK, Salminen M, Yamashiro T, Lappalainen P. (2003). Mouse MIM, a tissue-specific regulator of cytoskeletal dynamics, interacts with ATP-actin monomers through its C-terminal WH2 domain. J Biol Chem 278: 8452-8459. (Pubitemid 36800596)
31. Miranti CK. (2009). Controlling cell surface dynamics and signaling: how CD82/KAI1 suppresses metastasis. Cell Signal 21: 196-211.
32. Mosesson Y, Mills GB, Yarden Y. (2008). Derailed endocytosis: an emerging feature of cancer. Nat Rev Cancer 8: 835-850.
33. Parr C, Jiang WG. (2009). Metastasis suppressor 1 (MTSS1) demonstrates prognostic value and anti-metastatic properties in breast cancer. Eur J Cancer 45: 1673-1683.
34. Qian X, Karpova T, Sheppard AM, McNally J, Lowy DR. (2004). E-cadherin-mediated adhesion inhibits ligand-dependent activation of diverse receptor tyrosine kinases. EMBO J 23: 1739-1748. (Pubitemid 38649637)
35. Quinones GA, Jin J, Oro AE. (2010). I-BAR protein antagonism of endocytosis mediates directional sensing during guided cell migration. J Cell Biol 189: 353-367.
36. Sigismund S, Argenzio E, Tosoni D, Cavallaro E, Polo S, Di Fiore PP. (2008). Clathrin-mediated internalization is essential for sustained EGFR signaling but dispensable for degradation. Dev Cell 15: 209-219.
37. Sorkin A, Goh LK. (2009). Endocytosis and intracellular trafficking of ErbBs. Exp Cell Res 315: 683-696.
38. Thurlow JK, Pena Murillo CL, Hunter KD, Buffa FM, Patiar S, Betts G et al. (2010). Spectral clustering of microarray data elucidates the roles of microenvironment remodeling and immune responses in survival of head and neck squamous cell carcinoma. J Clin Oncol 28: 2881-2888.
39. Timpson P, Lynch DK, Schramek D, Walker F, Daly RJ. (2005). Cortactin overexpression inhibits ligand-induced downregulation of the epidermal growth factor receptor. Cancer Res 65: 3273-3280. (Pubitemid 40524611)
40. Timpson P, Wilson AS, Lehrbach GM, Sutherland RL, Musgrove EA, Daly RJ. (2007). Aberrant expression of cortactin in head and neck squamous cell carcinoma cells is associated with enhanced cell proliferation and resistance to the epidermal growth factor receptor inhibitor gefitinib. Cancer Res 67: 9304-9314. (Pubitemid 47535919)
41. Uhlenbrock K, Eberth A, Herbrand U, Daryab N, Stege P, Meier F et al. (2004). The RacGEF Tiam1 inhibits migration and invasion of metastatic melanoma via a novel adhesive mechanism. J Cell Sci 117: 4863-4871. (Pubitemid 39433450)
42. Woodcock SA, Rooney C, Liontos M, Connolly Y, Zoumpourlis V, Whetton AD et al. (2009). SRC-induced disassembly of adherens junctions requires localized phosphorylation and degradation of the rac activator tiam1. Mol Cell 33: 639-653.
43. Woodings JA, Sharp SJ, Machesky LM. (2003). MIM-B, a putative metastasis suppressor protein, binds to actin and to protein tyrosine phosphatase delta. Biochem J 371: 463-471. (Pubitemid 36547630)
44. Yang MH, Wu MZ, Chiou SH, Chen PM, Chang SY, Liu CJ et al. (2008). Direct regulation of TWIST by HIF-1alpha promotes metastasis. Nat Cell Biol 10: 295-305.