Atomic resolution model of the antibody Fc interaction with the complement C1q component

Molecular Immunology

Volumn 51, Issue 1, 2012, Pages 66-72

  Schneider, Sebastian ^a   Zacharias, Martin ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Antibody design; C1 globular domain; C1q Fc structure modeling; Complement activation; Complement component C1; IgG C1q interaction; Protein protein docking

Indexed keywords

COMPLEMENT COMPONENT C1Q; FC RECEPTOR;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; COMPLEMENT ACTIVATION; CONFORMATIONAL TRANSITION; HYDROGEN BOND; MOLECULAR DOCKING; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION;

COMPLEMENT ACTIVATION; COMPLEMENT C1Q; HUMANS; HYDROGEN BONDING; IMMUNOGLOBULIN FC FRAGMENTS; IMMUNOGLOBULIN G; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; PROTEIN BINDING;

EID: 84859567109     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2012.02.111     Document Type: Article

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