Nonprocessive [2 + 2]e - off-loading reductase domains from mycobacterial nonribosomal peptide synthetases

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 15, 2012, Pages 5681-5686

  Chhabra, Arush ^a   Haque, Asfarul S ^b   Pal, Ravi Kant ^b   Goyal, Aneesh ^b   Rai, Rajkishore ^c   Joshi, Seema ^d   Panjikar, Santosh ^e,f   Pasha, Santosh ^d   Sankaranarayanan, Rajan ^b   Gokhale, Rajesh S ^a,d,g  

^a NATIONAL INSTITUTE OF IMMUNOLOGY   (India)

^b CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

^c CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

^d CSIR INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY   (India)

^e EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^f AUSTRALIAN SYNCHROTRON   (Australia)

^g JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH   (India)

Author keywords

Chain release; Glycopeptidolipid; NAD(P)H; Tyrosine dependent oxidoreductase

Indexed keywords

ALCOHOL; ALDEHYDE; BACTERIAL ENZYME; GLYCOLIPID; LIPOPEPTIDE; NONRIBOSOMAL PEPTIDE SYNTHETASE; OXIDOREDUCTASE; THIOESTER;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME CONFORMATION; ENZYME MECHANISM; GLYCOPROTEIN SYNTHESIS; MYCOBACTERIUM; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; REDUCTION KINETICS;

ALCOHOLS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ELECTRONS; GLYCOPEPTIDES; LIPOPEPTIDES; MODELS, MOLECULAR; MYCOBACTERIUM TUBERCULOSIS; NADP; OXIDATION-REDUCTION; OXIDOREDUCTASES; PEPTIDE SYNTHASES; PROTEIN STRUCTURE, TERTIARY; SUBSTRATE SPECIFICITY;

CORYNEBACTERINEAE; MYCOBACTERIUM TUBERCULOSIS;

EID: 84859564582     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1118680109     Document Type: Article

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