메뉴 건너뛰기




Volumn 727, Issue , 2012, Pages 114-130

Notch signaling and the developing skeleton

Author keywords

[No Author keywords available]

Indexed keywords

NOTCH RECEPTOR;

EID: 84859509754     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4614-0899-4_9     Document Type: Article
Times cited : (15)

References (85)
  • 1
    • 0033813919 scopus 로고    scopus 로고
    • Transcriptional mechanisms ofchondrocyte differentiation
    • de Crombrugghe B, Lefebvre V, Behringer RRet al. Transcriptional mechanisms ofchondrocyte differentiation. Matrix Biol 2000; 19(5):389-394.
    • (2000) Matrix Biol , vol.19 , Issue.5 , pp. 389-394
    • De Crombrugghe, B.1    Lefebvre, V.2    Behringer, R.R.3
  • 2
    • 0035574614 scopus 로고    scopus 로고
    • Regulatory mechanisms in the pathways of cartilage and bone formation
    • de Crombrugghe B, Lefebvre V, Nakashima K. Regulatory mechanisms in the pathways of cartilage and bone formation. Cun Opin Cell Biol 2001; 13(6):721-727.
    • (2001) Cun Opin Cell Biol , vol.13 , Issue.6 , pp. 721-727
    • De Crombrugghe, B.1    Lefebvre, V.2    Nakashima, K.3
  • 3
    • 50849125368 scopus 로고    scopus 로고
    • More complicated than it looks: Assembly of Notch pathway transcription complexes
    • Kovall RA. More complicated than it looks: Assembly of Notch pathway transcription complexes. Oncogene 2008; 27(38):5099-5 109.
    • (2008) Oncogene , vol.27 , Issue.38 , pp. 5099-5109
    • Kovall, R.A.1
  • 4
    • 0037363922 scopus 로고    scopus 로고
    • HES and HERP families: Multiple effectors of the Notch signaling pathway
    • Iso T, Kedes L, Hamamori Y. HES and HERP families: Multiple effectors of the Notch signaling pathway. J Cell Physiol 2003; 194(3):237-255.
    • (2003) J Cell Physiol , vol.194 , Issue.3 , pp. 237-255
    • Iso, T.1    Kedes, L.2    Hamamori, Y.3
  • 5
    • 34447332808 scopus 로고    scopus 로고
    • The vertebrate segmentation clock and its role in skeletal birth defects
    • Shifley ET, Cole SE. The vertebrate segmentation clock and its role in skeletal birth defects. Birth Defects Res C Embryo Today 2007; 81(2):121-133.
    • (2007) Birth Defects Res C Embryo Today , vol.81 , Issue.2 , pp. 121-133
    • Shifley, E.T.1    Cole, S.E.2
  • 6
    • 33748300903 scopus 로고    scopus 로고
    • The long and short of it: Somite formation in mice
    • Gridley T. The long and short of it: Somite formation in mice. Dcv Dyn. 2006; 235(9):2330-2336.
    • (2006) Dcv Dyn. , vol.235 , Issue.9 , pp. 2330-2336
    • Gridley, T.1
  • 7
    • 34447316132 scopus 로고    scopus 로고
    • Genetic analysis ofmolecular oscillators inmammalian somitogenesis: Clues for studies of human vertebral disorders
    • SewellW, Kusumi K. Genetic analysis ofmolecular oscillators inmammalian somitogenesis: Clues for studies of human vertebral disorders. Birth Defects Res C Embryo Today 2007; 81(2):111-120.
    • (2007) Birth Defects Res C Embryo Today , vol.81 , Issue.2 , pp. 111-120
    • SewellW Kusumi, K.1
  • 8
    • 0028989016 scopus 로고
    • Notchl is required for the coordinate segmentation of somites
    • Conlon RA, Reaume AG, Rossant J. Notchl is required for the coordinate segmentation of somites. Development 1995; 121(5):1533-1545.
    • (1995) Development , vol.121 , Issue.5 , pp. 1533-1545
    • Conlon, R.A.1    Reaume, A.G.2    Rossant, J.3
  • 9
    • 0034702303 scopus 로고    scopus 로고
    • Embryonic lethality in mice homozygous for a processing-deficient allele ofNotchl
    • Huppert SS, Le A, Schroeter EH et al. Embryonic lethality in mice homozygous for a processing-deficient allele ofNotchl. Nature 2000; 405(6789):966-970.
    • (2000) Nature , vol.405 , Issue.6789 , pp. 966-970
    • Huppert, S.S.1    Le A Schroeter, E.H.2
  • 10
    • 0028971681 scopus 로고
    • Disruption of the mouse RBP-J kappa gene results in early embryonic death
    • Oka C, Nakano T, Wakeham A. et al. Disruption of the mouse RBP-J kappa gene results in early embryonic death. Development 1995; 121(l0):3291-3301.
    • (1995) Development , vol.121 , Issue.10 , pp. 3291-3301
    • Oka, C.1    Nakano, T.2    Wakeham, A.3
  • 11
    • 0032728957 scopus 로고    scopus 로고
    • Mice lacking both presenilin genes exhibit early embryonic patterning defects
    • Donoviel DB, Hadjantonakis AK, Ikeda Metal. Mice lacking both presenilin genes exhibit early embryonic patterning defects. Genes Dcv 1999; 13(21):2801-2810.
    • (1999) Genes Dcv , vol.13 , Issue.21 , pp. 2801-2810
    • Donoviel, D.B.1    Hadjantonakis, A.K.2    Ikeda, M.3
  • 12
    • 0035042946 scopus 로고    scopus 로고
    • The role ofpresenilin 1 during somite segmentation
    • Koizumi K, Nakajima M, Yuasa Set al. The role ofpresenilin 1 during somite segmentation. Development 2001; 128(8):1391-1402.
    • (2001) Development , vol.128 , Issue.8 , pp. 1391-1402
    • Koizumi, K.1    Nakajima, M.2    Yuasa, S.3
  • 13
    • 0030850751 scopus 로고    scopus 로고
    • Mesp2: A novel mouse gene expressed in the presegmented mesoderm and essential for segmentation initiation
    • Saga Y, Hata N, Koseki H et al. Mesp2: A novel mouse gene expressed in the presegmented mesoderm and essential for segmentation initiation. Genes Dcv 1997; 11(14):1827-1839.
    • (1997) Genes Dcv , vol.11 , Issue.14 , pp. 1827-1839
    • Saga, Y.1    Hata, N.2    Koseki, H.3
  • 14
    • 0031684290 scopus 로고    scopus 로고
    • Genetic rescue of segmentation defect in MesP2-deficient mice by MesPl gene replacement
    • Saga Y. Genetic rescue of segmentation defect in MesP2-deficient mice by MesPl gene replacement. Mech Dcv 1998; 75(1-2):53-66.
    • (1998) Mech Dcv , vol.75 , Issue.1-2 , pp. 53-66
    • Saga, Y.1
  • 15
    • 0030976083 scopus 로고    scopus 로고
    • Maintenance of somite borders in mice requires the Delta homologue Dill
    • Hrabe de Angelis M, McIntyre J, 2nd, Gossler A. Maintenance of somite borders in mice requires the Delta homologue Dill. Nature 1997; 386(6626):717-721.
    • (1997) Nature , vol.386 , Issue.6626 , pp. 717-721
    • Hrabe De Angelis, M.1    McIntyre, J.2    Gossler II, A.3
  • 16
    • 17344368196 scopus 로고    scopus 로고
    • The mouse pudgy mutation disrupts Delta homologue D113 and initiation of early somite boundaries
    • Kusumi K, Sun ES, Kerrebrock AW et al. The mouse pudgy mutation disrupts Delta homologue D113 and initiation of early somite boundaries. Nat Genet 1998;19(3):274-278.
    • (1998) Nat Genet , vol.19 , Issue.3 , pp. 274-278
    • Kusumi, K.1    Sun, E.S.2    Kerrebrock, A.W.3
  • 17
    • 0032560766 scopus 로고    scopus 로고
    • Defects in somite formation in lunatic fringe-deficient mice
    • Zhang N, Gridley T. Defects in somite formation in lunatic fringe-deficient mice. Nature 1998; 394(6691):374-377.
    • (1998) Nature , vol.394 , Issue.6691 , pp. 374-377
    • Zhang, N.1    Gridley, T.2
  • 18
    • 0032560814 scopus 로고    scopus 로고
    • Lunatic fringe is an essential mediator of somite segmentation and patterning
    • Evrard YA, Lun Y, Aulehla A et al. lunatic fringe is an essential mediator of somite segmentation and patterning. Nature 1998; 394(6691):377-381.
    • (1998) Nature , vol.394 , Issue.6691 , pp. 377-381
    • Evrard, Y.A.1    Lun, Y.2    Aulehla, A.3
  • 19
    • 0035887251 scopus 로고    scopus 로고
    • Dynamic expression and essential functions of Hes7 in somite segmentation
    • Bessho Y, Sakata R, Komatsu S et al. Dynamic expression and essential functions of Hes7 in somite segmentation. Genes Dcv 2001; 1 5(20):2642-2647.
    • (2001) Genes Dcv , vol.15 , Issue.20 , pp. 2642-2647
    • Bessho, Y.1    Sakata, R.2    Komatsu, S.3
  • 20
    • 0032715827 scopus 로고    scopus 로고
    • HRT1, HRT2 and HRT3: A new subclass of bHLH transcription factors marking specific cardiac, somitic and pharyngeal arch segments
    • Nakagawa O, Nakagawa M, Richardson JA et al. HRT1, HRT2 and HRT3: A new subclass of bHLH transcription factors marking specific cardiac, somitic and pharyngeal arch segments. Dcv Biol 1999; 216(1):72-84.
    • (1999) Dcv Biol , vol.216 , Issue.1 , pp. 72-84
    • Nakagawa, O.1    Nakagawa, M.2    Richardson, J.A.3
  • 21
    • 1942498907 scopus 로고    scopus 로고
    • The Notch target genes Hey 1 and Hey2 are required for embryonic vascular development
    • Fischer A, Schumacher N, Maier Metal. The Notch target genes Hey 1 and Hey2 are required for embryonic vascular development. Genes Dcv 2004; 18(8):901-911.
    • (2004) Genes Dcv , vol.18 , Issue.8 , pp. 901-911
    • Fischer, A.1    Schumacher, N.2    Maier, M.3
  • 22
    • 0034080402 scopus 로고    scopus 로고
    • The paired homeobox gene Uncx4 1 specifies pedicles, transverse processes and proximal ribs of the vertebral colunm
    • 12701
    • Leitges M, Neidhardt L, Haenig B et al. The paired homeobox gene Uncx4. 1 specifies pedicles, transverse processes and proximal ribs of the vertebral colunm. Development 2000; 12701):2259-2267.
    • (2000) Development , pp. 2259-2267
    • Leitges, M.1    Neidhardt, L.2    Haenig, B.3
  • 23
    • 70149123248 scopus 로고    scopus 로고
    • Notch pathway regulation of chondrocyte differentiation and proliferation during appendicular and axial skeleton development
    • Mead TJ, Yutzey KE. Notch pathway regulation of chondrocyte differentiation and proliferation during appendicular and axial skeleton development. Proc Natl Acad Sci USA 2009; 106(34):14420-14425.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.34 , pp. 14420-14425
    • Mead, T.J.1    Yutzey, K.E.2
  • 24
    • 26844502418 scopus 로고    scopus 로고
    • Transcriptional control of chondrocyte fate and differentiation
    • Lefebvre V, Smits P. Transcriptional control of chondrocyte fate and differentiation. Birth Defects Res C Embryo Today 2005; 75(3):200-212.
    • (2005) Birth Defects Res C Embryo Today , vol.75 , Issue.3 , pp. 200-212
    • Lefebvre, V.1    Smits, P.2
  • 25
    • 0036225281 scopus 로고    scopus 로고
    • Reaching a genetic and molecular understanding of skeletal development
    • Karsenty G, Wagner EF. Reaching a genetic and molecular understanding of skeletal development. Dcv Cell 2002; 2(4):389-406.
    • (2002) Dcv Cell , vol.2 , Issue.4 , pp. 389-406
    • Karsenty, G.1    Wagner, E.F.2
  • 26
    • 0023130144 scopus 로고
    • Quantitation of chondrocyte performance in growth-plate cartilage during longitudinal bone growth
    • Hunziker EB, Schenk RK, Cruz-Orive LM. Quantitation of chondrocyte performance in growth-plate cartilage during longitudinal bone growth. J Bone Joint Surg Am 1987; 69(2): 162-173.
    • (1987) J Bone Joint Surg Am , vol.69 , Issue.2 , pp. 162-173
    • Hunziker, E.B.1    Schenk, R.K.2    Cruz-Orive, L.M.3
  • 27
    • 0141866423 scopus 로고    scopus 로고
    • Morphogenesis and dysmorphogenesis of the appendicular skeleton
    • Shum L, Coleman CM, Hatakeyama Y et al. Morphogenesis and dysmorphogenesis of the appendicular skeleton. Birth Defects Res C Embryo Today 2003; 69(2):102-122.
    • (2003) Birth Defects Res C Embryo Today , vol.69 , Issue.2 , pp. 102-122
    • Shum, L.1    Coleman, C.M.2    Hatakeyama, Y.3
  • 28
    • 0033027858 scopus 로고    scopus 로고
    • VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation
    • Gerber HP, Vu TH, Ryan AM et al. VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation. Nat Med 1999; 5(6):623-628.
    • (1999) Nat Med , vol.5 , Issue.6 , pp. 623-628
    • Gerber, H.P.1    Vu, T.H.2    Ryan, A.M.3
  • 29
    • 0038687536 scopus 로고    scopus 로고
    • Developmental regulation of the growth plate
    • Kronenberg HM. Developmental regulation of the growth plate. Nature 2003; 423(6937):332-336.
    • (2003) Nature , vol.423 , Issue.6937 , pp. 332-336
    • Kronenberg, H.M.1
  • 30
    • 9144241202 scopus 로고    scopus 로고
    • Suppressionofdifferentiationandproliferationofearly chondrogenic cells by Notch
    • WatanabeN, TezukaY, Matsuno Ket al. Suppressionofdifferentiationandproliferationofearly chondrogenic cells by Notch. J Bone Miner Metab 2003; 21(6):344-352.
    • (2003) J Bone Miner Metab , vol.21 , Issue.6 , pp. 344-352
    • Watanabe, N.1    Tezuka, Y.2    Matsuno, K.3
  • 31
    • 33847011273 scopus 로고    scopus 로고
    • Notch signaling is required for the chondrogenic specification of mouse mesencephalic neural crest cells
    • Nakanishi K, Chan YS, Ito K. Notch signaling is required for the chondrogenic specification of mouse mesencephalic neural crest cells. Mech Dcv 2007; 124(3):190-203.
    • (2007) Mech Dcv , vol.124 , Issue.3 , pp. 190-203
    • Nakanishi, K.1    Chan, Y.S.2    Ito, K.3
  • 32
    • 33645893493 scopus 로고    scopus 로고
    • Involvement of Notch signaling in initiation of prechondrogenic condensation and nodule formation in limb bud micromass cultures
    • Fujimaki R, Toyama Y, Hozumi Net al. Involvement of Notch signaling in initiation of prechondrogenic condensation and nodule formation in limb bud micromass cultures. J Bone Miner Metab 2006; 24(3):191-198.
    • (2006) J Bone Miner Metab , vol.24 , Issue.3 , pp. 191-198
    • Fujimaki, R.1    Toyama, Y.2    Hozumi, N.3
  • 33
    • 77951229591 scopus 로고    scopus 로고
    • RBPj {kappa}-dependentNotch signalingregulatesmesenchymalprogenitor cellproliferation and differentiation during skeletal development
    • DongY, JesseAM, KohnAetal. RBPj {kappa}-dependentNotch signalingregulatesmesenchymalprogenitor cellproliferation and differentiation during skeletal development. Development 2010; 137(9): 1461-1471.
    • (2010) Development , vol.137 , Issue.9 , pp. 1461-1471
    • Dong, Y.1    Jesse, A.M.2    Kohn, A.3
  • 34
    • 43049138501 scopus 로고    scopus 로고
    • Notch signaling through Jagged-i is necessary to initiate chondrogenesis inhumanbone manow stromal cells butmustbe switched offto complete chondrogenesis
    • Oldershaw RA, Tew SR, Russell AM et al. Notch signaling through Jagged-i is necessary to initiate chondrogenesis inhumanbone manow stromal cells butmustbe switched offto complete chondrogenesis. Stem Cells 2008; 26(3):666-674.
    • (2008) Stem Cells , vol.26 , Issue.3 , pp. 666-674
    • Oldershaw, R.A.1    Tew, S.R.2    Russell, A.M.3
  • 35
    • 0036830491 scopus 로고    scopus 로고
    • The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of SoxS and Soxo
    • Akiyama H, Chaboissier MC, Martin JF et al. The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of SoxS and Soxo. Genes Dcv 2002; 16(21):2813-2828.
    • (2002) Genes Dcv , vol.16 , Issue.21 , pp. 2813-2828
    • Akiyama, H.1    Chaboissier, M.C.2    Martin, J.F.3
  • 36
    • 51849085670 scopus 로고    scopus 로고
    • Repression of chondrogenesis through binding of notch signaling proteins HES-i and HEY-i to N-box domains in the COL2A1 enhancer site
    • Grogan SP, 0lcc T, Hiraoka K et al. Repression of chondrogenesis through binding of notch signaling proteins HES-i and HEY-i to N-box domains in the COL2A1 enhancer site. Arthritis Rheum 2008; 58(9):2754-2763.
    • (2008) Arthritis Rheum , vol.58 , Issue.9 , pp. 2754-2763
    • Grogan, S.P.1    Olcc, T.2    Hiraoka, K.3
  • 37
    • 0033035607 scopus 로고    scopus 로고
    • Delta-i negatively regulates the transition from prehypertrophic to hypertrophic chondrocytes during cartilage formation
    • Crowe R, Zikherman J, Niswander L. Delta-i negatively regulates the transition from prehypertrophic to hypertrophic chondrocytes during cartilage formation. Development 1999; 126(5):987-998.
    • (1999) Development , vol.126 , Issue.5 , pp. 987-998
    • Crowe, R.1    Zikherman, J.2    Niswander, L.3
  • 38
    • 40449084522 scopus 로고    scopus 로고
    • Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation
    • Hilton MJ, Tu X, Wu X et al. Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation. Nat Med 2008; 14(3):306-3 14.
    • (2008) Nat Med , vol.14 , Issue.3 , pp. 306-314
    • Hilton, M.J.1    Tu, X.2    Wu, X.3
  • 39
    • 77953811432 scopus 로고    scopus 로고
    • HES1 andHES5 AreDispensable forCartilage andEndochondral Bone Formation
    • KarlssonC, Brantsing C, KageyamaRet al. HES1 andHES5 AreDispensable forCartilage andEndochondral Bone Formation. Cells Tissues Organs 2010.
    • (2010) Cells Tissues Organs
    • Karlsson, C.1    Brantsing, C.2    Kageyama, R.3
  • 40
    • 38449093315 scopus 로고    scopus 로고
    • Regulation of osteogenic differentiation during skeletal development
    • Deng ZL, SharffKA, Tang Net al. Regulation of osteogenic differentiation during skeletal development. Front Biosci 2005; 13:2001-2021.
    • (2008) Front Biosci , vol.13 , pp. 2001-2021
    • Deng, Z.L.1    Sharff, K.A.2    Tang, N.3
  • 41
    • 26844574574 scopus 로고    scopus 로고
    • Osteo-chondroprogenitor cells are derived from Sox9 expressing precursors
    • Akiyama H, Kim JE, Nakashima K et al. Osteo-chondroprogenitor cells are derived from Sox9 expressing precursors. Proc Natl Acad Sci USA 2005; 102(40:14665-14670.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.41 , pp. 14665-14670
    • Akiyama, H.1    Kim, J.E.2    Nakashima, K.3
  • 42
    • 0142026227 scopus 로고    scopus 로고
    • Osteogenic differentiation of the mesenchymal progenitor cells, Kusa is suppressed by Notch signaling
    • Shindo K, Kawashima N, Sakamoto K et al. Osteogenic differentiation of the mesenchymal progenitor cells, Kusa is suppressed by Notch signaling. Exp Cell Res 2003; 290(2):370-380.
    • (2003) Exp Cell Res , vol.290 , Issue.2 , pp. 370-380
    • Shindo, K.1    Kawashima, N.2    Sakamoto, K.3
  • 43
    • 0345688655 scopus 로고    scopus 로고
    • Notch 1 impairs osteoblastic cell differentiation
    • 14402
    • Sciaudone M, Gazzeno E, Priest L et al. Notch 1 impairs osteoblastic cell differentiation. Endocrinology 2003; 14402):5631-5639.
    • (2003) Endocrinology , pp. 5631-5639
    • Sciaudone, M.1    Gazzeno, E.2    Priest, L.3
  • 44
    • 4444246433 scopus 로고    scopus 로고
    • Coordinated activation of notch Wnt and transforming growth factor-beta signaling pathways in bone morphogenic protein 2-induced osteogenesis. Notch target gene Heyl inhibitsmineralizationandRunx2transcriptionalactivity
    • Zamurovic N, Cappellen D, Rohner D et al. Coordinated activation of notch, Wnt and transforming growth factor-beta signaling pathways in bone morphogenic protein 2-induced osteogenesis. Notch target gene Heyl inhibitsmineralizationandRunx2transcriptionalactivity. JBiolChem2004; 279(36):37704-3771 5.
    • (2004) JBiolChem , vol.279 , Issue.36 , pp. 37704-37715
    • Zamurovic, N.1    Cappellen, D.2    Rohner, D.3
  • 45
    • 47949130093 scopus 로고    scopus 로고
    • Notch inhibits osteoblast differentiation and causes osteopenia
    • Zanotti S, Smerdel-Ramoya A, Stadmeyer L et al. Notch inhibits osteoblast differentiation and causes osteopenia. Endocrinology 2008; 149(8):3890-3899.
    • (2008) Endocrinology , vol.149 , Issue.8 , pp. 3890-3899
    • Zanotti, S.1    Smerdel-Ramoya, A.2    Stadmeyer, L.3
  • 46
    • 33646550902 scopus 로고    scopus 로고
    • Notch 1 overexpression inhibits osteoblastogenesis by suppressing Wnt beta-catenin but not bone morphogenetic protein signaling
    • Deregowski V, Gazzeno E, Priest Let al. Notch 1 overexpression inhibits osteoblastogenesis by suppressing Wnt beta-catenin but not bone morphogenetic protein signaling. J Biol Chem 2006; 28 1(10):6203-6210.
    • (2006) J Biol Chem , vol.281 , Issue.10 , pp. 6203-6210
    • Deregowski, V.1    Gazzeno, E.2    Priest, L.3
  • 47
    • 40449139405 scopus 로고    scopus 로고
    • Dimorphic effects of Notch signaling in bone homeostasis
    • Engin F, Yao Z, Yang T et al. Dimorphic effects of Notch signaling in bone homeostasis. Nat Med 2008; 14(3):299-305.
    • (2008) Nat Med , vol.14 , Issue.3 , pp. 299-305
    • Engin, F.1    Yao, Z.2    Yang, T.3
  • 48
    • 0030678549 scopus 로고    scopus 로고
    • Osf2 Cbfai: A transcriptional activator of osteoblast differentiation
    • Ducy P, Zhang R, Geoffroy V et al. Osf2 Cbfai: A transcriptional activator of osteoblast differentiation. Cell 1997; 89(5):747-754.
    • (1997) Cell , vol.89 , Issue.5 , pp. 747-754
    • Ducy, P.1    Zhang, R.2    Geoffroy, V.3
  • 49
    • 0030666372 scopus 로고    scopus 로고
    • Cbfal, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development
    • Otto F, Thornell AP, Crompton T et al. Cbfal, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell 1997; 89(5):765-771.
    • (1997) Cell , vol.89 , Issue.5 , pp. 765-771
    • Otto, F.1    Thornell, A.P.2    Crompton, T.3
  • 50
    • 0030684749 scopus 로고    scopus 로고
    • Targeted disruption ofCbfal results in a complete lack of bone formation owing to maturational arrest of osteoblasts
    • Komori T, Yagi H, Nomura S et al. Targeted disruption ofCbfal results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell 1997; 89(5):755-764.
    • (1997) Cell , vol.89 , Issue.5 , pp. 755-764
    • Komori, T.1    Yagi, H.2    Nomura, S.3
  • 51
    • 0036155343 scopus 로고    scopus 로고
    • Stimulation of osteoblastic cell differentiation by Notch
    • Tezuka K, Yasuth M, Watanabe Net al. Stimulation of osteoblastic cell differentiation by Notch. J Bone Miner Res 2002; 17(2):231-239.
    • (2002) J Bone Miner Res , vol.17 , Issue.2 , pp. 231-239
    • Tezuka, K.1    Yasuth, M.2    Watanabe, N.3
  • 52
    • 18144384703 scopus 로고    scopus 로고
    • Criticalregulationofbone morphogenetic protein-inducedosteoblastic differentiation by Deltal Jaggedl-activated Notchl signaling
    • Nobta M, Tsukazaki T, ShibataY et al. Criticalregulationofbone morphogenetic protein-inducedosteoblastic differentiation by Deltal Jaggedl-activated Notchl signaling. J Biol Chem 2005; 280(16): 15842-15848.
    • (2005) J Biol Chem , vol.280 , Issue.16 , pp. 15842-15848
    • Nobta, M.1    Tsukazaki, T.2    Shibata, Y.3
  • 53
    • 0043267732 scopus 로고    scopus 로고
    • Genetic regulation of osteoclast development and function
    • Teitelbaum SL, Ross FP. Genetic regulation of osteoclast development and function. Nat Rev Genet 2003; 4(8):638-649.
    • (2003) Nat Rev Genet , vol.4 , Issue.8 , pp. 638-649
    • Teitelbaum, S.L.1    Ross, F.P.2
  • 54
    • 0025332897 scopus 로고
    • The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene
    • Yoshida H, Hayashi S, Kunisada T et al. The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene. Nature 1990; 345(6274):442-444.
    • (1990) Nature , vol.345 , Issue.6274 , pp. 442-444
    • Yoshida, H.1    Hayashi, S.2    Kunisada, T.3
  • 55
    • 0031005576 scopus 로고    scopus 로고
    • Osteoprotegerin: A novel secreted protein involved in the regulation of bone density
    • Simon WS, Lacey DL, Dunstan CR et al. Osteoprotegerin: A novel secreted protein involved in the regulation of bone density. Cell 1997; 89(2):309-319.
    • (1997) Cell , vol.89 , Issue.2 , pp. 309-319
    • Simon, W.S.1    Lacey, D.L.2    Dunstan, C.R.3
  • 56
    • 0037443389 scopus 로고    scopus 로고
    • Regulation of osteoclast development by Notch signaling directed to osteoclast precursors and through stromal cells
    • Yamada T, Yamazaki H, Yamane T et al. Regulation of osteoclast development by Notch signaling directed to osteoclast precursors and through stromal cells. Blood 2003; 101(6):2227-2234.
    • (2003) Blood , vol.101 , Issue.6 , pp. 2227-2234
    • Yamada, T.1    Yamazaki, H.2    Yamane, T.3
  • 57
    • 42749095897 scopus 로고    scopus 로고
    • NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells
    • Bai S, Kopan R, Zou Wet al. NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells. J Biol Chem 2008; 283(10):6509-6518.
    • (2008) J Biol Chem , vol.283 , Issue.10 , pp. 6509-6518
    • Bai, S.1    Kopan, R.2    Zou, W.3
  • 58
    • 53549111642 scopus 로고    scopus 로고
    • The association of Notch2 and NF-kappaB accelerates RANKL-induced osteoclastogenesis
    • Fukushima H, Nakao A, Okamoto F et al. The association of Notch2 and NF-kappaB accelerates RANKL-induced osteoclastogenesis. Mol Cell Biol 2008; 28(20):6402-6412.
    • (2008) Mol Cell Biol , vol.28 , Issue.20 , pp. 6402-6412
    • Fukushima, H.1    Nakao, A.2    Okamoto, F.3
  • 59
    • 34250674386 scopus 로고    scopus 로고
    • Abnormal vertebral segmentation and the notch signaling pathway in man
    • Turnpenny PD, Alman B, Cornier AS et al. Abnormal vertebral segmentation and the notch signaling pathway in man. Dcv Dyn 2007; 236(6):1456-1474.
    • (2007) Dcv Dyn , vol.236 , Issue.6 , pp. 1456-1474
    • Turnpenny, P.D.1    Alman, B.2    Cornier, A.S.3
  • 60
    • 0034028904 scopus 로고    scopus 로고
    • Mutations in the human delta homologue, DLL3, cause axial skeletal defects in spondylocostal dysostosis
    • Bulman MP, Kusumi K, Frayling TM et al. Mutations in the human delta homologue, DLL3, cause axial skeletal defects in spondylocostal dysostosis. Nat Genet 2000; 24(4):438-441.
    • (2000) Nat Genet , vol.24 , Issue.4 , pp. 438-441
    • Bulman, M.P.1    Kusumi, K.2    Frayling, T.M.3
  • 61
    • 0036332950 scopus 로고    scopus 로고
    • Axial skeletal defects caused by mutation inthe spondylocostal dysplasia pudgy gene D113 are associated with disruption ofthe segmentation clock within the presomitic mesoderm
    • Dunwoodie SL, Clements M, SparrowDB etal. Axial skeletal defects caused by mutation inthe spondylocostal dysplasia pudgy gene D113 are associated with disruption ofthe segmentation clock within the presomitic mesoderm. Development 2002; 129(7): 1795-1806.
    • (2002) Development , vol.129 , Issue.7 , pp. 1795-1806
    • Dunwoodie, S.L.1    Clements, M.2    Sparrow, D.B.3
  • 62
    • 2442713782 scopus 로고    scopus 로고
    • Mutated MESP2 causes spondylocostal dysostosis in humans
    • Whittock NV, Sparrow DB, Wouters MA et al. Mutated MESP2 causes spondylocostal dysostosis in humans. Am J Hum Genet 2004; 74(6):1249-1254.
    • (2004) Am J Hum Genet , vol.74 , Issue.6 , pp. 1249-1254
    • Whittock, N.V.1    Sparrow, D.B.2    Wouters, M.A.3
  • 63
    • 29244458644 scopus 로고    scopus 로고
    • Mutation of the LUNATIC FRINGE gene in humans causes spondylocostal dysostosis with a severe vertebral phenotype
    • Sparrow DB, Chapman G, Wouters MA et al. Mutation of the LUNATIC FRINGE gene in humans causes spondylocostal dysostosis with a severe vertebral phenotype. Am J Hum Genet 2006; 78(1):28-37.
    • (2006) Am J Hum Genet , vol.78 , Issue.1 , pp. 28-37
    • Sparrow, D.B.1    Chapman, G.2    Wouters, M.A.3
  • 64
    • 56049123626 scopus 로고    scopus 로고
    • Mutation of Hairy-and-Enhancer-of-Split-7 in humans causes spondylocostal dysostosis
    • Sparrow DB, Guillen-Navano E, Fatkin D et al. Mutation of Hairy-and-Enhancer-of-Split-7 in humans causes spondylocostal dysostosis. Hum Mol Genet 2008; 17(23):3761-3766.
    • (2008) Hum Mol Genet , vol.17 , Issue.23 , pp. 3761-3766
    • Sparrow, D.B.1    Guillen-Navano, E.2    Fatkin, D.3
  • 65
    • 77952674210 scopus 로고    scopus 로고
    • Two novel missense mutations in HAIRY-ANDENHANCER-OF-SPLIT-7 in a family with spondylocostal dysostosis
    • Sparrow DB, Sillence D, Wouters MA et al. Two nove1 missense mutations in HAIRY-ANDENHANCER-OF-SPLIT-7 in a family with spondylocostal dysostosis. Em J Hum Genet 2010.
    • (2010) Em J Hum Genet
    • Sparrow, D.B.1    Sillence, D.2    Wouters, M.A.3
  • 66
    • 35348993727 scopus 로고    scopus 로고
    • Dll3 and Notchl genetic interactions model axial segmental and craniofacial malformations of human birth defects
    • Loomes KM, Stevens SA, O'Brien ML et al. Dll3 and Notchl genetic interactions model axial segmental and craniofacial malformations of human birth defects. Dcv Dyn 2007; 236(10):2943-2951.
    • (2007) Dcv Dyn , vol.236 , Issue.10 , pp. 2943-2951
    • Loomes, K.M.1    Stevens, S.A.2    O'Brien, M.L.3
  • 67
    • 0036065333 scopus 로고    scopus 로고
    • Periodic Lunatic fringe expressionis controlled during segmentation by a cyclic transcriptional enhancer responsive to notch signaling
    • MoralesAV, YasuthY, Ish-Horowicz D. Periodic Lunatic fringe expressionis controlled during segmentation by a cyclic transcriptional enhancer responsive to notch signaling. Dcv Cell 2002; 3(1):63-74.
    • (2002) Dcv Cell , vol.3 , Issue.1 , pp. 63-74
    • Morales, A.V.1    Yasuth, Y.2    Ish-Horowicz, D.3
  • 68
    • 0038875342 scopus 로고    scopus 로고
    • Alagille syndrome is caused by mutations in human Jagged 1, which encodes a ligand for Notchi
    • Li L, Krantz ID, Deng Yet al. Alagille syndrome is caused by mutations in human Jagged 1, which encodes a ligand for Notchi. Nat Genet 1997; 16(3):243-251.
    • (1997) Nat Genet , vol.16 , Issue.3 , pp. 243-251
    • Li, L.1    Krantz, I.D.2    Deng, Y.3
  • 69
    • 0030914459 scopus 로고    scopus 로고
    • Mutations in the human Jaggedi gene are responsible for Alagille syndrome
    • Ellcahloun AG, Pike BL et al. Mutations in the human Jaggedi gene are responsible for Alagille syndrome. Nat Genet 1997; 16(3):235-242.
    • (1997) Nat Genet , vol.16 , Issue.3 , pp. 235-242
    • Ellcahloun, A.G.1    Pike, B.L.2
  • 70
    • 0037390535 scopus 로고    scopus 로고
    • Notch signaling and inherited disease syndromes
    • Spec No 1:R9-13
    • Gridley T. Notch signaling and inherited disease syndromes. Hum Mol Genet 2003; 12 Spec No 1:R9-13. 71.
    • (2003) Hum Mol Genet , vol.12
    • Gridley, T.1
  • 71
    • 33745232796 scopus 로고    scopus 로고
    • NOTCH2 mutations cause Alagille syndrome, a heterogeneous disorder of the notch signaling pathway
    • McDaniell R, War hen DM, Sanchez-Lara PA et al. NOTCH2 mutations cause Alagille syndrome, a heterogeneous disorder of the notch signaling pathway. Am J Hum Genet 2006; 79(1):169-173.
    • (2006) Am J Hum Genet , vol.79 , Issue.1 , pp. 169-173
    • McDaniell, R.1    Warhen, D.M.2    Sanchez-Lara, P.A.3
  • 72
    • 13144290942 scopus 로고    scopus 로고
    • Deficits in size-adjusted bone mass in children with Alagille syndrome
    • Olsen IE, Ittenbach RF, Rovner AJ et al. Deficits in size-adjusted bone mass in children with Alagille syndrome. J Pediatr Gastroenterol Nutr 2005; 40(1):76-82.
    • (2005) J Pediatr Gastroenterol Nutr , vol.40 , Issue.1 , pp. 76-82
    • Olsen, I.E.1    Ittenbach, R.F.2    Rovner, A.J.3
  • 73
    • 0032897080 scopus 로고    scopus 로고
    • Embryonic lethality and vascular defects in mice lacking the Notch ligand Jaggedi
    • Xue Y, Gao X, Lindsell CE et al. Embryonic lethality and vascular defects in mice lacking the Notch ligand Jaggedi. Hum Mol Genet 1999; 8(5):723-730.
    • (1999) Hum Mol Genet , vol.8 , Issue.5 , pp. 723-730
    • Xue, Y.1    Gao, X.2    Lindsell, C.E.3
  • 74
    • 0036339631 scopus 로고    scopus 로고
    • A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jagi haploinsufficiency
    • McCright B, Lozier J, Gridley T. A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jagi haploinsufficiency. Development 2002; 129(4): 1075-1082.
    • (2002) Development , vol.129 , Issue.4 , pp. 1075-1082
    • McCright, B.1    Lozier, J.2    Gridley, T.3
  • 75
    • 0034851142 scopus 로고    scopus 로고
    • Expression of notch homologues in the synovium of rheumatoid arthritis and osteoarthritis patients
    • Ishii H, Nakazawa M, Yoshino S et al. Expression of notch homologues in the synovium of rheumatoid arthritis and osteoarthritis patients. Rheumatol Int 2001; 21(1):10-14.
    • (2001) Rheumatol Int , vol.21 , Issue.1 , pp. 10-14
    • Ishii, H.1    Nakazawa, M.2    Yoshino, S.3
  • 76
    • 51349094632 scopus 로고    scopus 로고
    • Notchi Jaggedi and HESS are abundantly expressedinosteoarthritis
    • KarlssonC, Brantsing C, Egell Set al. Notchi, Jaggedi and HESS are abundantly expressedinosteoarthritis. Cells Tissues Organs 2008; 188(3):287-298.
    • (2008) Cells Tissues Organs , vol.188 , Issue.3 , pp. 287-298
    • Karlsson, C.1    Brantsing, C.2    Egell, S.3
  • 77
    • 74149089912 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 induced chondrocyte cluster formation in experimentally wounded articular cartilage is blocked by soluble Jagged-i
    • Khan IM, Palmer EA, Archer CW. Fibroblast growth factor-2 induced chondrocyte cluster formation in experimentally wounded articular cartilage is blocked by soluble Jagged-i. Osteoarthritis Cartilage 2010; 18(2):208-219.
    • (2010) Osteoarthritis Cartilage , vol.18 , Issue.2 , pp. 208-219
    • Khan, I.M.1    Palmer, E.A.2    Archer, C.W.3
  • 78
    • 64549149292 scopus 로고    scopus 로고
    • Notch signaling contributes to the pathogenesis of human osteosarcomas
    • Engin F, Bertin T, Ma O et al. Notch signaling contributes to the pathogenesis of human osteosarcomas. Hum Mol Genet 2009; 18(8):1464-1470.
    • (2009) Hum Mol Genet , vol.18 , Issue.8 , pp. 1464-1470
    • Engin, F.1    Bertin, T.2    Ma, O.3
  • 79
    • 49649103793 scopus 로고    scopus 로고
    • Critical role of notch signaling in osteosarcoma invasion and metastasis
    • Zhang P, Yang Y, Zweidler-McKay PA et al. Critical role of notch signaling in osteosarcoma invasion and metastasis. Clin Cancer Res 2008; 14(10):2962-2969.
    • (2008) Clin Cancer Res , vol.14 , Issue.10 , pp. 2962-2969
    • Zhang, P.1    Yang, Y.2    Zweidler-McKay, P.A.3
  • 80
    • 67349182923 scopus 로고    scopus 로고
    • Inhibition of Notch pathway prevents osteosarcoma growth by cell cycle regulation
    • Tanaka M, Setoguchi T, Hirotsu M et al. Inhibition of Notch pathway prevents osteosarcoma growth by cell cycle regulation. Br J Cancer 2009; 100(12):1957-1965.
    • (2009) Br J Cancer , vol.100 , Issue.12 , pp. 1957-1965
    • Tanaka, M.1    Setoguchi, T.2    Hirotsu, M.3
  • 81
    • 77952668917 scopus 로고    scopus 로고
    • Regulation of NOTCH signaling by reciprocal inhibition of HES 1 and Deltex 1 and its role in osteosarcoma invasiveness
    • Zhang P, Yang Y, Nob R et al. Regulation of NOTCH signaling by reciprocal inhibition of HES 1 and Deltex 1 and its role in osteosarcoma invasiveness. Oncogene 2010; 29(20):2916-2926.
    • (2010) Oncogene , vol.29 , Issue.20 , pp. 2916-2926
    • Zhang, P.1    Yang, Y.2    Nob, R.3
  • 82
    • 77953674754 scopus 로고    scopus 로고
    • How the NOTCH pathway contributes to the ability of osteosarcoma cells to metastasize
    • Hughes DP. How the NOTCH Pathway Contributes to the Ability of Osteosarcoma Cells to Metastasize. Cancer Treat Res 2010; 152:479-496.
    • (2010) Cancer Treat Res , vol.152 , pp. 479-496
    • Hughes, D.P.1
  • 83
    • 33748335730 scopus 로고    scopus 로고
    • Kinetics of tamoxifen-regulated Crc activity in mice using a cartilage-specific CreER(T) to assay temporal activity windows along the proximodistal limb skeleton
    • Nakamura E, Nguyen MT, Mackem S. Kinetics of tamoxifen-regulated Crc activity in mice using a cartilage-specific CreER(T) to assay temporal activity windows along the proximodistal limb skeleton. Dcv Dyn 2006; 235(9):2603-2612.
    • (2006) Dcv Dyn , vol.235 , Issue.9 , pp. 2603-2612
    • Nakamura, E.1    Nguyen, M.T.2    Mackem, S.3
  • 84
    • 59149096379 scopus 로고    scopus 로고
    • BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway
    • Kamiya N, Ye L, Kobayashi T et al. BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway. Development 2008; 135(22):3801-3811.
    • (2008) Development , vol.135 , Issue.22 , pp. 3801-3811
    • Kamiya, N.1    Ye, L.2    Kobayashi, T.3
  • 85
    • 67650064589 scopus 로고    scopus 로고
    • Mice expressing QJFP and CreER in osteochondro progenitor cells in the periosteum
    • Kawanami A, Matsushita T, Chan YY et al. Mice expressing QJFP and CreER in osteochondro progenitor cells in the periosteum. Biochem Biophys Res Commun 2009; 386(3):477-482.
    • (2009) Biochem Biophys Res Commun , vol.386 , Issue.3 , pp. 477-482
    • Kawanami, A.1    Matsushita, T.2    Chan, Y.Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.