메뉴 건너뛰기




Volumn 114, Issue 2, 2009, Pages 100-109

T lymphocyte maturation is impaired in healthy young individuals carrying trisomy 21 (Down syndrome)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 7;

EID: 65549115151     PISSN: 19447558     EISSN: None     Source Type: Journal    
DOI: 10.1352/2009.114.100-109     Document Type: Article
Times cited : (39)

References (45)
  • 1
    • 0031757825 scopus 로고    scopus 로고
    • Role of interleukin-7 in T-cell development from hematopoietic stem cells
    • Akashi, K., Kondo, M., & Weissman, I. L. (1998). Role of interleukin-7 in T-cell development from hematopoietic stem cells. Immunological Reviews, 165, 13-28. (Pubitemid 28524199)
    • (1998) Immunological Reviews , vol.165 , pp. 13-28
    • Akashi, K.1    Kondo, M.2    Weissman, I.L.3
  • 2
    • 0037342104 scopus 로고    scopus 로고
    • Memory lanes
    • DOI 10.1038/ni0303-212
    • Badovinac, V. P., & Harty, J. H. T. (2003). Memory lanes. Nature Immunology 4, 212-213. (Pubitemid 36322128)
    • (2003) Nature Immunology , vol.4 , Issue.3 , pp. 212-213
    • Badovinac, V.P.1    Harty, J.T.2
  • 3
    • 0027362785 scopus 로고
    • + subpopulations expressing CD45RA and CD29 antigens in the peripheral blood of adults and children with Down syndrome
    • Barena, M. J., Echaniz, P., Garciaserrano, C., & Cuadrado, E. (1993). Imbalance of the CD4+ subpopulations expressing CD45RA and CD29 antigens in the peripheral blood adults and children with Down syndrome. Scandinavian Journal of Immunology, 38, 323-326. (Pubitemid 23294772)
    • (1993) Scandinavian Journal of Immunology , vol.38 , Issue.4 , pp. 323-326
    • Barrena, M.J.1    Echaniz, P.2    Garcia-Serrano, C.3    Cuadrado, E.4
  • 4
    • 0021746090 scopus 로고
    • Immunodeficiency in Down's syndrome: Analysis by OKT monoclonal antibodies
    • Bertotto, A., Gerli, R., Fabietti, G., Crupi, S., Arcangeli, C., Cernetti, C., et al. (1984). Immunodeficiency in Down syndrome: Analysis by OKT monoclonal antibodies. Thymus, 6, 365-367. (Pubitemid 15175852)
    • (1984) Thymus , vol.6 , Issue.6 , pp. 365-367
    • Bertotto, A.1    Gerli, R.2    Fabietti, G.3
  • 5
    • 79954598013 scopus 로고    scopus 로고
    • Immune dysregulation and T-cell activation antigens in HIV infection
    • J. P. Robinson & G. Babcock (Eds.), New York: Wiley Liss
    • Biasin, M., Colombo, F., Piconi, S., & Clerici, M. (2000). Immune dysregulation and T-cell activation antigens in HIV infection. In J. P. Robinson & G. Babcock (Eds.), Cellular aspects of HIV infection (pp. 155-178). New York: Wiley Liss.
    • (2000) Cellular Aspects of HIV Infection , pp. 155-178
    • Biasin, M.1    Colombo, F.2    Piconi, S.3    Clerici, M.4
  • 6
    • 0041330412 scopus 로고    scopus 로고
    • + T cells in HIV-infected children
    • DOI 10.1023/A:1025325718213
    • Correa, R., Resino, S., & Munoz-Fernandez, M. A. (2003). Increased interleukin-7 plasma levels are associated with recovery of CD4(+) T cells in HIV-infected children. Journal of Clinical Immunology, 23, 401-406. (Pubitemid 37083194)
    • (2003) Journal of Clinical Immunology , vol.23 , Issue.5 , pp. 401-406
    • Correa, R.1    Resino, S.2    Munoz-Fernandez, M.A.3
  • 7
    • 0025618405 scopus 로고
    • Precocious aging of the immune system in Down syndrome: Alteration of B lymphocytes, T-lymphocyte subsets, and cells with natural killer markers
    • Cossarizza, A., Monti, D., Montagnani, G., Ortolani, O., Masi, M., Zannotti, M., & Franceschi, C. (1990). Precocious aging of the immune system in Down syndrome: Alteration of B lymphocytes, T-lymphocyte subsets, and cells with natural killer markers. American Journal of Medical Genetics (Suppl. 7), 213-218.
    • (1990) American Journal of Medical Genetics , Issue.SUPPL. 7 , pp. 213-218
    • Cossarizza, A.1    Monti, D.2    Montagnani, G.3    Ortolani, O.4    Masi, M.5    Zannotti, M.6    Franceschi, C.7
  • 8
    • 0025732162 scopus 로고
    • Age-related expansion of functionally inefficient cells with markers of natural killer activity in Down syndrome
    • Cossarizza, A., Ortolani, O., Fořti, E., Montagnani, G., Paganelli, R., Zannotti, M., et al. (1991). Age-related expansion of functionally inefficient cells with markers of natural killer activity in Down syndrome. Blood, 77, 1263-1270.
    • (1991) Blood , vol.77 , pp. 1263-1270
    • Cossarizza, A.1    Ortolani, O.2    Fořti, E.3    Montagnani, G.4    Paganelli, R.5    Zannotti, M.6
  • 9
    • 0029871363 scopus 로고    scopus 로고
    • Immune dysfunction in Down's syndrome: Primary immune deficiency or early senescence of the immune system?
    • DOI 10.1006/clin.1996.0031
    • Cuadrado, E., & Barrena, M. J. (1996). Immune dysfunction in Down syndrome: Primary immune deficiency or early senescence of the immune system? Clinical Immunology and Immunopathology, 78, 209-214. (Pubitemid 26127983)
    • (1996) Clinical Immunology and Immunopathology , vol.78 , Issue.3 , pp. 209-214
    • Cuadrado, E.1    Barrena, M.J.2
  • 10
    • 28844486209 scopus 로고    scopus 로고
    • Intrinsic abnormalities of lymphocyte counts in children with Down syndrome
    • DOI 10.1016/j.jpeds.2005.07.022, PII S0022347605006979
    • de Hingh, Y. C., van der Vossen, P. W., Gemen, E. F., Mulder, A. B, Hop, W. C., Brus, F., & de Vries, E. (2005). Intrinsic abnormalities of lymphocyte counts in children with Down syndrome. Journal of Pediatrics, 147, 744-747. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db = pubmed&cmd = Search&itool =pubmed-Abstract & term = %22 van +der+Vossen+PW°/ o22%5BAuthor%5D (Pubitemid 41774828)
    • (2005) Journal of Pediatrics , vol.147 , Issue.6 , pp. 744-747
    • De Hingh, Y.C.M.1    Van Der Vossen, P.W.2    Gemen, E.F.A.3    Mulder, A.B.4    Hop, W.C.J.5    Brus, F.6    De Vries, E.7
  • 11
    • 28844433582 scopus 로고    scopus 로고
    • Down syndrome: Immunologic and epidemiologic associations-Enigmas remain
    • Douglas, S. D. (2005). Down syndrome: Immunologic and epidemiologic associations-Enigmas remain. Journal of Pediatrics, 147, 723-725.
    • (2005) Journal of Pediatrics , vol.147 , pp. 723-725
    • Douglas, S.D.1
  • 12
    • 0020051011 scopus 로고
    • Immunological and virological investigations in Down's syndrome
    • Fekete, G., Kulcsar, G., Dan, P., Nasz, I., Schüler, D., & Dobos, M. (1982). Immunological and virological investigations in Down syndrome. European Journal of Pediatrics, 38, 59-62 (Pubitemid 12171200)
    • (1982) European Journal of Pediatrics , vol.138 , Issue.1 , pp. 59-62
    • Fekete, G.1    Kulcsar, G.2    Dan, P.3
  • 13
    • 31744440030 scopus 로고    scopus 로고
    • Interferon-gamma and interleukin-4-producing T cells in Down's syndrome
    • DOI 10.1016/j.neulet.2005.10.048, PII S0304394005012292
    • Franciotta, D., Verri, A., Cardini, E., Androni, L., De Amici, M., Moratti, R., & Nespoli, L. (2006). Interferon-gamma and interleukin- 4producing T cells in Down syndrome. Neuroscience Letters, 395, 67-70. (Pubitemid 43175804)
    • (2006) Neuroscience Letters , vol.395 , Issue.1 , pp. 67-70
    • Franciotta, D.1    Verri, A.2    Zardini, E.3    Andreoni, L.4    De Amici, M.5    Moratti, R.6    Nespoli, L.7
  • 15
    • 28844476656 scopus 로고    scopus 로고
    • Risk of death for children with Down syndrome and sepsis
    • DOI 10.1016/j.jpeds.2005.06.032, PII S0022347605005871
    • Garrison, M. M., Jeffries, H., & Christakis, D. A. (2005). Risk of death for children with and without Down syndrome who have sepsis. Journal of Pediatrics, 147, 748-752. (Pubitemid 41774829)
    • (2005) Journal of Pediatrics , vol.147 , Issue.6 , pp. 748-752
    • Garrison, M.M.1    Jeffries, H.2    Christakis, D.A.3
  • 16
    • 0035905477 scopus 로고    scopus 로고
    • + T cells
    • DOI 10.1084/jem.194.12.1711
    • Geginat, J., Sallusto, F., & Lanzavecchia, A. (2001). Cytokine-driven proliferation and differentiation of human naive, CM, and EM CD4(+) T cells. Journal of Experimental Medicine, 194, 1711-1719. (Pubitemid 34028651)
    • (2001) Journal of Experimental Medicine , vol.194 , Issue.12 , pp. 1711-1719
    • Geginat, J.1    Sallusto, F.2    Lanzavecchia, A.3
  • 19
    • 0031656033 scopus 로고    scopus 로고
    • + T cells
    • DOI 10.1002/(SICI)1521-4141(199810)28:10<3057::AID-IMMU3057>3.0. CO;2-Z
    • Hassan, J., & Reen, D. J. (1998). IL-7 promotes the survival and maturation but not differentiation of human post-thymic CD4+ T cells. European Journal of Immunology, 28, 3057-3065. (Pubitemid 28470251)
    • (1998) European Journal of Immunology , vol.28 , Issue.10 , pp. 3057-3065
    • Hassan, J.1    Reen, D.J.2
  • 21
    • 0021335943 scopus 로고
    • Cell-mediated immunodeficiency in Down's syndrome: Normal IL-2 production but inverted ratio of T cell subsets
    • Karttunen, R., Nurmi, T., Ilonen, J., & Surcell, H. M. (1984). Cell mediated immunodeficiency in Down syndrome: Normal IL2 production but inverted ratio of T cell subsets. Clinical and Experimental Immunology, 55, 257-263. (Pubitemid 14223461)
    • (1984) Clinical and Experimental Immunology , vol.55 , Issue.2 , pp. 257-263
    • Karttunen, R.1    Nurmi, T.2    Ilonen, J.3    Surcel, H.M.4
  • 22
    • 0036884742 scopus 로고    scopus 로고
    • Progressive differentiation and selection of the fittest in the immune response
    • DOI 10.1038/nri959
    • Lanzavecchia, A., & Sallusto, F. (2002). Progressive differentiation and selection of the fittest in the immune response. Nature Reviews Immunology, 2, 982-987. (Pubitemid 37323221)
    • (2002) Nature Reviews Immunology , vol.2 , Issue.12 , pp. 982-987
    • Lanzavecchia, A.1    Sallusto, F.2
  • 23
    • 0037022910 scopus 로고    scopus 로고
    • Inflammation and atherosclerosis
    • DOI 10.1161/hc0902.104353
    • Libby, P., & Ridker, P. M. (2002). Inflammation and atherosclerosis. Circulation, 105, 1135-1143. (Pubitemid 34212626)
    • (2002) Circulation , vol.105 , Issue.9 , pp. 1135-1143
    • Libby, P.1    Ridker, P.M.2    Maseri, A.3
  • 25
    • 0021274337 scopus 로고
    • + cells
    • Maccario, R., Ugazio, A. G., Nespoli, L., & Bugio, G. R. (1984). Lymphocyte subpopulations in Down syndrome: High percentage of circulating HNK1+, Leu2a+ cells. Clinical and Experimental Immunology, 57, 220-226. (Pubitemid 14083848)
    • (1984) Clinical and Experimental Immunology , vol.57 , Issue.1 , pp. 220-226
    • Maccario, R.1    Ugazio, A.G.2    Nespoli, L.3
  • 26
    • 0035282766 scopus 로고    scopus 로고
    • IL-7 increases both thymic-dependent and thymicindependent T cell regeneration after bone marrow transplantation
    • Mackall, C. L., Fry, T. J., Bare, C., Morgan, P., Galbraith, A., & Gress, R. E. (2001). IL-7 increases both thymic-dependent and thymicindependent T cell regeneration after bone marrow transplantation. Blood, 97, 1491-1499.
    • (2001) Blood , vol.97 , pp. 1491-1499
    • Mackall, C.L.1    Fry, T.J.2    Bare, C.3    Morgan, P.4    Galbraith, A.5    Gress, R.E.6
  • 28
    • 0026515305 scopus 로고
    • Down syndrome (DS) peripheral blood contains phenotypically mature CD3+TCR alpha, beta+ cells but abnormal proportions of TCR alpha, beta+, TCR gamma, delta+, and CD4+ CD45RA+ cells: Evidence for an inefficient release of mature T cells by the Down syndrome thymus
    • Murphy, M., & Epstein, L. B. (1992). Down syndrome (DS) peripheral blood contains phenotypically mature CD3+TCR alpha, beta+ cells but abnormal proportions of TCR alpha, beta+, TCR gamma, delta+, and CD4+ CD45RA+ cells: Evidence for an inefficient release of mature T cells by the Down syndrome thymus. Clinical Immunology and Im munopathology, 62, 245-251.
    • (1992) Clinical Immunology and im Munopathology , vol.62 , pp. 245-251
    • Murphy, M.1    Epstein, L.B.2
  • 29
    • 0026673105 scopus 로고
    • Tumor necrosis factor alpha and interferon gamma expression in hu man thymus: Localization and overexpressior in Down syndrome (trisomy 21)
    • Murphy, M., Friend, D. S., Pike-Nobile, L., & Epstein, L. B. (1992). Tumor necrosis factor alpha and interferon gamma expression in hu man thymus: Localization and overexpressior in Down syndrome (trisomy 21). Journal of, Immunology, 149, 2506-2512.
    • (1992) Journal Of, Immunology , vol.149 , pp. 2506-2512
    • Murphy, M.1    Friend, D.S.2    Pike-Nobile, L.3    Epstein, L.B.4
  • 30
    • 0027160002 scopus 로고
    • Overexpression of LFA-1 and ICAM-1 in Down syndrome thymus: Implications for abnormal thymocyte maturation
    • Murphy, M., Insoft, R. M., Pike-Nobile, L., Derbin, K. S., & Epstein, L. B. (1993). Overexpression of LFA-1 and ICAM-I in Down syndrome thymus. Implications for abnormal thymocyte maturation. Journal of Immunology, 150, 5696-5703. (Pubitemid 23180683)
    • (1993) Journal of Immunology , vol.150 , Issue.12 , pp. 5696-5703
    • Murphy, M.1    Insoft, R.M.2    Pike-Nobile, L.3    Derbin, K.S.4    Epstein, L.B.5
  • 33
    • 0023492605 scopus 로고
    • Altered T-cell subsets and defective T-cell function in young children with Down syndrome (trisomy-21)
    • Noble, R. L., & Warren, R. P. (1987). Altered T-cell subsets and defective T-cell function in young children with Down syndrome (trisomy-21). Immunological Investigations, 16, 371-382. (Pubitemid 18008705)
    • (1987) Immunological Investigations , vol.16 , Issue.5 , pp. 371-382
    • Noble, R.L.1    Warren, R.P.2
  • 34
    • 0034074882 scopus 로고    scopus 로고
    • Partial impairment of immune functions in peripheral blood leukocytes from aged men with Down's syndrome
    • DOI 10.1006/clim.2000.4834
    • Park, E., Alberti, J., Mehta, P., Dalton, A., Sersen, E., & Schuller-Levis, G. (2000). Partial impairment of immune functions in peripheral blood leukocytes from aged men with Down syndrome. Clinical Immunology, 95, 62-69. (Pubitemid 30202818)
    • (2000) Clinical Immunology , vol.95 , Issue.1 , pp. 62-69
    • Park, E.1    Alberti, J.2    Mehta, P.3    Dalton, A.4    Sersen, E.5    Schuller-Levis, G.6
  • 35
    • 0022572635 scopus 로고
    • Abnormalities of the in vitro cellular and humoral responses to tetanus and influenza antigens with concomitant numerical alterations in lymphocyte subsets in down syndrome (trisomy 21)
    • Philip, R., Berger, A. C., McManus, N. H., Warner, N. H., Peacock, M. A., & Epstein, L. B. (1986). Abnormalities of the in vitro cellular and humoral responses to tetanus and influenza antigens with concomitant numerical alterations in lymphocyte subsets in Down syndrome (trisomy 21). Journal of Immunology, 136, 1661-1667. (Pubitemid 16119572)
    • (1986) Journal of Immunology , vol.136 , Issue.5 , pp. 1661-1667
    • Philip, R.1    Berger, A.C.2    McManus, N.H.3
  • 37
    • 31144475596 scopus 로고    scopus 로고
    • Aging of the immune system: A risk factor for autoimmunity?
    • Prelog, M. (2006). Aging of the immune system: A risk factor for autoimmunity? Autoimmunity Reviews, 5, 136-139.
    • (2006) Autoimmunity Reviews , vol.5 , pp. 136-139
    • Prelog, M.1
  • 38
    • 0033554726 scopus 로고    scopus 로고
    • Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
    • Sallusto, F., Lenig, D., Forster, R., Lipp, L., & Lanzavecchia, A. (1999). Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature, 401, 708-712.
    • (1999) Nature , vol.401 , pp. 708-712
    • Sallusto, F.1    Lenig, D.2    Forster, R.3    Lipp, L.4    Lanzavecchia, A.5
  • 39
    • 32044457728 scopus 로고    scopus 로고
    • Increased plasma interleukin-7 level correlates with decreased CD127 and increased CD132 extracellular expression on T cell subsets in patients with HIV-1 infection
    • DOI 10.1086/499309
    • Sasson, S. C., Zaunders, J. J., Zanetti, G., King, E. M., Merlin, K. M., & Smith, D. E., et al. (2006). Increased plasma interleukin-7 level correlates with decreased CD 127 and increased CD 132 extracellular expression on T cell subsets in patients with HIV-1 infection. Journal of Infectious Diseases, 193, 505-514. (Pubitemid 43202741)
    • (2006) Journal of Infectious Diseases , vol.193 , Issue.4 , pp. 505-514
    • Sasson, S.C.1    Zaunders, J.J.2    Zanetti, G.3    King, E.M.4    Merlin, K.M.5    Smith, D.E.6    Stanley, K.K.7    Cooper, D.A.8    Kelleher, A.D.9
  • 40
    • 33846165796 scopus 로고    scopus 로고
    • + T cell differentiation: Contrasting pictures in blood and tonsillar lymphoid tissue
    • DOI 10.1086/510248
    • Sauce, D., Larsen, M., Leese, A. M., Millar, D., Khan, N., Hislop, A. D., & Rickinson, A. B. (2007). IL-7R alpha versus CCR7 and CD45 as markers of virus-specific CD8(+) T cell differentiation: Contrasting pictures in blood and tonsillar lymphoid tissue. Journal of Infectious Diseases, 195, 268-278. (Pubitemid 46080059)
    • (2007) Journal of Infectious Diseases , vol.195 , Issue.2 , pp. 268-278
    • Sauce, D.1    Larsen, M.2    Leese, A.M.3    Millar, D.4    Khan, N.5    Hislop, A.B.6    Rickinson, A.7
  • 41
    • 0031854015 scopus 로고    scopus 로고
    • T cell activation deficiency associated with an aberrant pattern of protein tyrosine phosphorylation after CD3 perturbation in Down's syndrome
    • Scotese, I., Gaetaniello, L., Matarese, G., Lecora, M., Racioppi, L., & Pignata, C. (1998). T cell activation deficiency associated with aberrant pattern of protein tyrosine phosphorylation after CD3 perturbation in Down syndrome. Pediatric Research, 44, 252-258. (Pubitemid 28347905)
    • (1998) Pediatric Research , vol.44 , Issue.2 , pp. 252-258
    • Scotese, I.1    Gaetaniello, L.2    Matarese, G.3    Lecora, M.4    Racioppi, L.5    Pignata, C.6
  • 44
    • 0037340417 scopus 로고    scopus 로고
    • Lineage relationship and protective immunity of memory CD8T cell subsets
    • DOI 10.1038/ni889
    • Wherry, E. J., Teichgraber, V., Becker, T. C., Masopust, D., Kaech, S. M., Antia, R., et al. (2003). Lineage relationship and protective immunity of memory CD8 T cell subsets. Nature Immunology, 4, 225-234. (Pubitemid 36322131)
    • (2003) Nature Immunology , vol.4 , Issue.3 , pp. 225-234
    • Wherry, E.J.1    Teichgraber, V.2    Becker, T.C.3    Masopust, D.4    Kaech, S.M.5    Antia, R.6
  • 45
    • 0037160991 scopus 로고    scopus 로고
    • Mortality associated with Down's syndrome in the USA from 1983 to 1997: A population-based study
    • DOI 10.1016/S0140-6736(02)08092-3
    • Yang, Q., Rasmussen, S. A., & Friedman, J. M. (2002). Mortality associated with Down syndrome in the USA from 1983 to 1997: A population based study. Lancet, 359, 1019-1025. (Pubitemid 34286539)
    • (2002) Lancet , vol.359 , Issue.9311 , pp. 1019-1025
    • Yang, Q.1    Rasmussen, S.A.2    Friedman, J.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.