Deregulated Stat3 signaling dissociates pulmonary inflammation from emphysema in gp130 mutant mice

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 302, Issue 7, 2012, Pages

  Ruwanpura, Saleela M ^a   McLeod, Louise ^a   Miller, Alistair ^a   Jones, Jessica ^b   Vlahos, Ross ^b   Ramm, Georg ^c   Longano, Anthony ^c   Bardin, Philip G ^c   Bozinovski, Steven ^b   Anderson, Gary P ^b   Jenkins, Brendan J ^a  

^a MONASH UNIVERSITY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c MONASH MEDICAL CENTRE   (Australia)

Author keywords

Apoptosis; Chronic obstructive pulmonary disease; Cytokines; Interleukin 6; Signal transducer and activator of transcription 1

Indexed keywords

GLYCOPROTEIN GP 130; INTERLEUKIN 6; PROTEINASE; STAT3 PROTEIN;

AGED; AIRWAY OBSTRUCTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENETIC COMPLEMENTATION; HUMAN; HUMAN TISSUE; HYPERACTIVITY; IMMUNOHISTOCHEMISTRY; LUNG ALVEOLUS CELL; LUNG EMPHYSEMA; LUNG PARENCHYMA; MALE; MOLECULAR PATHOLOGY; MOUSE; MOUSE MUTANT; NONHUMAN; PHENOTYPE; PNEUMONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; PROTEINASE INHIBITION; SIGNAL TRANSDUCTION; UPREGULATION;

AGED; ANIMALS; APOPTOSIS; CYTOKINE RECEPTOR GP130; EMPHYSEMA; FEMALE; HUMANS; INTERLEUKIN-6; LUNG; MALE; MICE; MICE, TRANSGENIC; PNEUMONIA; PULMONARY ALVEOLI; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR;

EID: 84859472876     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00285.2011     Document Type: Article

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