Prevalidation study of the BALB/c 3T3 cell transformation assay for assessment of carcinogenic potential of chemicals

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 744, Issue 1, 2012, Pages 20-29

  Tanaka, Noriho ^a   Bohnenberger, Susanne ^b   Kunkelmann, Thorsten ^b   Munaro, Barbara ^c   Ponti, Jessica ^c   Poth, Albrecht ^b   Sabbioni, Enrico ^c   Sakai, Ayako ^a   Salovaara, Susan ^c   Sasaki, Kiyoshi ^a   Thomas, B Claire ^c   Umeda, Makoto ^a  

^a HATANO RESEARCH INSTITUTE   (Japan)

^b Harlan   (Switzerland)

^c JOINT RESEARCH CENTRE   (Italy)

Author keywords

Alternative methods; Carcinogenicity; Cell transformation assay; In vitro test; Validation

Indexed keywords

2 METHYLANILINE; 3 METHYLCHOLANTHRENE; ANTHRACENE; BENZO[A]PYRENE; N (2 FLUORENYL)ACETAMIDE; PHENANTHRENE;

ANIMAL CELL; ARTICLE; AUDIOVISUAL EQUIPMENT; BAGG ALBINO MOUSE; CARCINOGENESIS; CELL ASSAY; CELL LINE; CELL TRANSFORMATION; CELL TRANSFORMATION ASSAY; CLINICAL PROTOCOL; CONTROLLED STUDY; EVALUATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPRODUCIBILITY; STANDARDIZATION;

ANIMAL TESTING ALTERNATIVES; ANIMALS; BALB 3T3 CELLS; CARCINOGENICITY TESTS; CARCINOGENS; CELL TRANSFORMATION, NEOPLASTIC; MICE; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS; VALIDATION STUDIES AS TOPIC;

ANIMALIA;

EID: 84859432815     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2011.12.008     Document Type: Article

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